Olsart-H 40 mg Tablet belongs to a group of medications called 'anti-hypertensives' primarily used for lowering high blood pressure (hypertension) by removing extra fluid (electrolytes) from the body. High blood pressure is a chronic condition in which the blood's force against the artery wall is high. As a result, it increases the risk of heart-related diseases like heart attack, heart failure, stroke, irregular heartbeat, and other complications.

Olsart-H 40 mg Tablet is a combination of two medicines: Olmesartan medoximil and Hydrochlorothiazide. Olmesartan medoximil is a prodrug and breaks down into active form, i.e., olmesartan once absorbed in the GIT (Gastrointestinal tract). It is an angiotensin receptor blocker (ARB) that blocks the hormone angiotensin, thereby relaxing and widening the narrowed blood vessels. This allows the blood to flow more smoothly in the blood vessels, and the heart can pump more efficiently. On the other hand, Hydrochlorothiazide is a diuretic or water pill that works by removing extra water/fluid and certain electrolyte overload from the body. Together, Olsart-H 40 mg Tablet lowers the fluid overload, raises blood pressure, improves blood flow, and reduces the future risk of a heart attack and stroke.

You can take Olsart-H 40 mg Tablet with food or without food with a glass of water. Do not chew, bite, or break it. Your doctor will advise you on how often you take your tablets based on your medical condition. In some cases, you may experience nausea, upset stomach, dehydration, headache, diarrhoea, electrolyte imbalance, dizziness, and decreased blood pressure. Most of these side effects of Olsart-H 40 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not use potassium supplements or salt substitutes unless your doctor tells you. In rare cases, Olsart-H 40 mg Tablet can cause a condition that results in a skeletal muscle problem, leading to further kidney failure. If you notice unexplained muscle pain, dark colour urine, tenderness, or weakness, especially if you also have a fever or unexplained tiredness, immediately contact the doctor.

Try not to stop taking this medicine of your own. Let your doctor know about this, as it may cause a rise in blood pressure and increase heart disease and stroke risk. Inform your doctor if you are suffering from kidney, liver, or heart disease or are diabetic. If you are pregnant or breastfeeding, do not take Olsart-H 40 mg Tablet as it is a category D pregnancy drug and may harm the baby. Do not use Olsart-H 40 mg Tablet if you cannot urinate, are dehydrated, have low blood pressure (hypotension), and have or have had cardiogenic shock (sudden stopping of blood flow to the heart). Please tell your doctor if you are taking any other medicines or are allergic to this medicine. Reducing table salt (sodium chloride) in your food often helps lower blood pressure.

Olsart-H 40 mg Tablet is primarily used to treat high blood pressure. Olsart-H 40 mg Tablet is a combination of two medicines: Olmesartan and Hydrochlorothiazide. Olmesartan medoximil is a prodrug and breaks down into active form, i.e., olmesartan once absorbed in the GIT (Gastrointestinal tract). It is an angiotensin receptor blocker (ARB) that blocks the hormone angiotensin and relaxes blood vessels. This allows the blood to flow more smoothly in the blood vessels, and the heart can pump more efficiently. Hydrochlorothiazide (diuretic or water pill); removes extra water and certain electrolytes from the body. Together, both lower fluid overload, and blood pressure, improve blood flow and reduce the future risk of a heart attack.

Do not use Olsart-H 40 mg Tablet if you are pregnant, planning for pregnancy, or unable to urinate (anuria). If you have diabetes and taking Olsart-H 40 mg Tablet with other blood pressure-lowering pills like 'aliskiren', immediately stop taking both together and consult a doctor. Besides this, it is contraindicated in low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart), and aortic stenosis (heart valve problem). Olsart-H 40 mg Tablet may pass into breast milk, so before starting Olsart-H 40 mg Tablet , either you need to stop nursing, or you should not take Olsart-H 40 mg Tablet while breastfeeding. Please inform your doctor before surgery if you are taking Olsart-H 40 mg Tablet as it needs to be stopped because it might lower the blood pressure further if taken along with local anaesthesia. Avoid potassium salt or its substitute intake while using Olsart-H 40 mg Tablet to avoid any electrolyte imbalance.