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Written By ,
Reviewed By Sunny S , MBBS
48 Hrs returnable
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Whats That

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Composition :

SPIRONOLACTONE-25MG

Manufacturer/Marketer :

Zeelab Pharmacy Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Therapeutic Class

DIURETIC

Country of origin

India
Other Info - ON65165

FAQs

Onoctone 25 Tablet contains spironolactone, which is a short-acting diuretic prescribed for the treatment of resistant oedema (fluid overload) associated with pulmonary hypertension (high blood pressure in the lungs), heart failure, and hepatic cirrhosis (chronic liver damage). Onoctone 25 Tablet works by increasing the amount of urine that is passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, it helps lower high blood pressure, reducing the chances of heart attack, stroke, or angina (chest pain) in the future.

Yes, Onoctone 25 Tablet may cause changes in the menstrual cycle. It can lead to irregular and painful periods. In addition to this, taking Onoctone 25 Tablet can also lead to pain and swelling of the breast. If any of these problems persist and discomfort increases, please consult your doctor for the best advice.

Onoctone 25 Tablet is known to increase the blood potassium level. So, if you take any extra potassium supplements or potassium-rich foods such as bananas and broccoli, it may lead to an excessive increase in potassium level and lead to hyperkalemia.

It is a condition in which people are unable to urinate. If you have anuria, please be very cautious while taking Onoctone 25 Tablet to lead to kidney damage.

Gynecomastia is an enlargement of the breast, especially in males. Onoctone 25 Tablet may cause enlarged breasts in both males and females. If you feel breast enlargement, please stop taking Onoctone 25 Tablet as stopping Onoctone 25 Tablet may help in this symptom going away.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

You are recommended not to consume alcohol along with Onoctone 25 Tablet to avoid unpleasant side effects.

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Pregnancy

Caution

Onoctone 25 Tablet is not suggested during pregnancy since there is insufficient evidence on how it may impact a growing infant.

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Breast Feeding

Unsafe

Breast-feeding must be avoided during treatment with Onoctone 25 Tablet.

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Driving

Unsafe

It is not recommended to drive after taking Onoctone 25 Tablet as it may occasionally cause drowsiness due to orthostatic hypotension (sudden drop in blood pressure on standing from a lying position).

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Liver

Caution

Onoctone 25 Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. Your doctor may adjust your dose depending upon your current liver conditions.

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Kidney

Caution

Onoctone 25 Tablet to be taken with caution, especially if you have a history of kidney diseases/conditions. Your doctor may adjust your dose depending upon your current liver conditions.

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Children

Unsafe

Onoctone 25 Tablet is not recommended for children below 12 years of age.

About Onoctone 25 Tablet

Onoctone 25 Tablet belongs to a class of medicine called 'diuretics' (water pills), primarily used to remove excess water from the body and treat fluid overload (oedema). It also maintains the bloodstream's potassium level and prevents hypertension (high blood pressure due to oedema (fluid retention). Oedema or fluid overload is associated with pulmonary hypertension (high blood pressure in the lung) or heart failure (irregular heart pumping). Leg swelling is the main characteristic of oedema, accompanied by shortness of breath, chest pain (angina), abnormal heart rhythms (arrhythmia), and swelling in other hands or abdomen areas.

Onoctone 25 Tablet contains spironolactone, which is a short-acting diuretic prescribed for the treatment of resistant oedema (fluid overload) associated with pulmonary hypertension (high blood pressure in the lungs), heart failure, and hepatic cirrhosis (chronic liver damage). Onoctone 25 Tablet works by increasing the amount of urine that is passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, it helps lower high blood pressure, reducing the chances of heart attack, stroke, or angina (chest pain) in the future.

Your doctor will advise you how often you take Onoctone 25 Tablet based on your medical condition. In some cases, you may experience low blood pressure (hypotension), dehydration, dizziness, electrolyte disturbances (potassium and sodium), increased creatinine level in the blood, headache, nausea, and breast enlargement in males. Most of these side effects of Onoctone 25 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking Onoctone 25 Tablet of your own as doing so may raise your blood pressure, thereby increasing the risk of heart disease and stroke. Inform your doctor if you are suffering from any kidney, liver, or heart disease. If you are pregnant or breastfeeding, please tell your doctor so that the dosage of Onoctone 25 Tablet can be prescribed accordingly. Please tell your doctor if you are taking any other medicines or are allergic to Onoctone 25 Tablet. Reducing the amount of table salt (sodium chloride) in your food often relieves the body's swelling.

Uses of Onoctone 25 Tablet

Hypertension (high blood pressure), Edema/Oedema (fluid overload)

Medicinal Benefits Mweb

Medicinal Benefits

Onoctone 25 Tablet contains 'Spironolactone', which acts as a short-acting diuretic (water pill) prescribed for the treatment of resistant oedema (fluid overload) associated with pulmonary hypertension (high blood pressure in the lungs), heart failure, and hepatic cirrhosis (chronic liver damage). Onoctone 25 Tablet works by increasing the amount of urine that is passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, it helps lower high blood pressure, reducing the chances of heart attack, stroke, or angina (chest pain) in the future.

Directions for Use

Tablet: Swallow it as a whole with water; do not crush, break or chew it.Oral Suspension: Shake the bottle well before each use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper.

Side Effects of Onoctone 25 Tablet

  • Low blood pressure (hypotension)
  • Dehydration
  • Dizziness
  • Electrolyte disturbances (potassium and sodium)
  • Increased creatinine level in the blood
  • Headache
  • Nausea
  • Breast enlargement in males

Drug Warnings

Onoctone 25 Tablet should not be given to the people allergic to Onoctone 25 Tablet, have low blood pressure (less than 90 mm of Hg), have had a heart attack, kidney disease (with creatinine clearance less than 30 mL/min), liver disease, pregnant women, or planning to get pregnant and breastfeeding women. Besides this, it is contraindicated in low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart), anuria (unable to urinate), diabetes, and aortic stenosis (heart valve problem). Onoctone 25 Tablet can pass into breast milk, but its effect on the baby is unknown, so it is better to tell your doctor if you are taking Onoctone 25 Tablet and breastfeeding. Do not take any extra potassium supplements or potassium-rich foods (bananas, broccoli) with Onoctone 25 Tablet, as it may lead to an excessive increase in blood potassium level (hyperkalemia).
 

Drug-Drug Interactions

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SpironolactoneEplerenone
Critical
SpironolactoneAmiloride
Critical

Drug-Drug Interactions

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SpironolactoneEplerenone
Critical
How does the drug interact with Onoctone 25 Tablet:
Combining Eplerenone with Spiranolactone may significantly increase potassium levels in the blood which can lead to kidney issues and irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Onoctone 25 Tablet and eplerenone, it is not recommended as it can lead to an interaction. You can take these medicines if prescribed by a doctor. Consult a doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or an irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
SpironolactoneAmiloride
Critical
How does the drug interact with Onoctone 25 Tablet:
Coadministration of Amiloride with Onoctone 25 Tablet may increase potassium levels in the blood.

How to manage the interaction:
Taking Amiloride with Onoctone 25 Tablet is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop taking any medication without doctor's advice.
SpironolactonePotassium citrate
Severe
How does the drug interact with Onoctone 25 Tablet:
Taking Onoctone 25 Tablet with potassium citrate may increase potassium levels in the blood which can lead to kidney problems and abnormal heart rhythm.

How to manage the interaction:
Although taking Onoctone 25 Tablet and potassium citrate together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. It is advised to reduce the intake of potassium-rich foods. Do not discontinue any medications without a doctor's advice.
SpironolactoneLisinopril
Severe
How does the drug interact with Onoctone 25 Tablet:
Using lisinopril together with Onoctone 25 Tablet may cause hyperkalemia (increase the levels of potassium in your blood).

How to manage the interaction:
Taking Lisinopril with Onoctone 25 Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feeling of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop taking any medication without doctor's advise.
SpironolactoneTacrolimus
Severe
How does the drug interact with Onoctone 25 Tablet:
Taking Onoctone 25 Tablet with tacrolimus may increase potassium levels in the blood and even kidney and heart problems.

How to manage the interaction:
Although taking Onoctone 25 Tablet and tacrolimus together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without consulting doctor.
SpironolactoneFosinopril
Severe
How does the drug interact with Onoctone 25 Tablet:
Using fosinopril together with Onoctone 25 Tablet may cause hyperkalemia (increase the levels of potassium in your blood).

How to manage the interaction:
Taking Fosinopril with Onoctone 25 Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feeling of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop taking any medication without doctor's advise.
SpironolactonePotassium chloride
Severe
How does the drug interact with Onoctone 25 Tablet:
Taking Onoctone 25 Tablet with Potassium chloride may increase potassium levels in the blood which can lead to kidney problems and abnormal heart rhythm.

How to manage the interaction:
Taking Potassium chloride with Onoctone 25 Tablet can possibly result in an interaction, it can be taken if a doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feeling of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop taking any medication without doctor's advise.
SpironolactoneLosartan
Severe
How does the drug interact with Onoctone 25 Tablet:
Coadministration of Losartan with Onoctone 25 Tablet can increase potassium levels in blood which can lead to severe conditions like kidney problems and irregular heart rhythm.

How to manage the interaction:
Taking Losartan with Onoctone 25 Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feeling of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop taking any medication without doctor's advise.
SpironolactoneCiclosporin
Severe
How does the drug interact with Onoctone 25 Tablet:
Taking Onoctone 25 Tablet with ciclosporin may increase potassium levels in the blood.

How to manage the interaction:
Although taking Onoctone 25 Tablet and ciclosporin together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience slow, fast, or uneven heartbeat, rapid breathing, numbness or tingly feeling, and muscle pain or weakness. Do not stop using any medications without consulting a doctor.
SpironolactoneTelmisartan
Severe
How does the drug interact with Onoctone 25 Tablet:
Taking Onoctone 25 Tablet with telmisartan may increase potassium levels in the blood.

How to manage the interaction:
Although there is a possible interaction, telmisartan can be taken with Onoctone 25 Tablet if prescribed by the doctor. Consult the prescriber if you experience symptoms of high potassium such as nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. Maintain adequate fluid intake during treatment with these medications. Do not discontinue the medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • METOPROLOL
  • RAMIPRIL
  • HYDROCHLOROTHIAZIDE
  • ATORVASTATIN
  • CARBAMAZEPINE
  • PHENOBARBITAL
  • ALPRAZOLAM
  • CYCLOSPORINE
  • IBUPROFEN
  • ASPIRIN

Habit Forming

No

Special Advise

  • Treatment with Onoctone 25 Tablet requires regular monitoring of serum potassium, sodium, and creatinine level. Besides this, your kidney function tests should be done regularly.

Diet & Lifestyle Advise

  • Consume antioxidant-rich food. Blueberries, cherries, tomatoes, squash, and bell peppers are high in antioxidants.
  • Eat natural diuretic foods. Asparagus, beets, green beans, grapes, onion, leafy greens, pineapple, leeks, pumpkin, and garlic are all-natural diuretic foods.
  • Use healthy cooking oils like soybean, olive, canola, and coconut oil.
  • You should avoid refined foods such as white bread, spaghetti, sugar, and red meat.
  • Reduce or eliminate Trans fatty acids, which are found in commercially baked items such as cookies, cakes, crackers, French fries, onion rings, doughnuts, and processed foods.
  • Avoid consumption of too much salt or salty food.
  • Keep your weight under control with a BMI of 19.5-24.9.
  • Regular physical activity or exercise like walking improves your blood flow.
  • When possible, elevate your legs or the swollen area on a chair or pillows.
  • Avoid standing or sitting for extended periods of time.
  • Avoid chronic stress as it can raise your blood pressure.
  • Spend time with your loved ones to cope with stress and practice mindfulness techniques.
  • Quitting smoking and alcohol consumption is the best strategy to lower the risk of many health complications.

Onoctone 25 Tablet Substitute

Substitutes safety advice
  • Aldactone Tablet 15's

    by Others

    2.19per tablet
  • Spironot-25 Tablet 10's

    by Others

    1.92per tablet
  • Spirolact 25mg Tablet

    by Others

    1.93per tablet
  • Silectone 25 Tablet

    by Others

    1.92per tablet
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