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Reviewed By Sunny S , MBBS
48 Hrs returnable
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Whats That

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Composition :

VINCRISTINE-1MG

Manufacturer/Marketer :

Neon Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTINEOPLASTIC

Country of origin

India

Manufacturer/Marketer address

140, Damji Samji Industrial Complex, Mahakali Caves Rd., Andheri(East), Mumbai-93.
Other Info - ONV0004

FAQs

Onvinc 1mg Injection contains Vincristine, which works by blocking DNA replication (genetic material) in the cancer cells. Hence, this stops the further growth and multiplication of the cancer cells. 

Onvinc 1mg Injection if not administered properly, and if it leaks from the vein, it may cause tissue damage. So, if you see any redness, pain, swelling, burning, skin sores or leaking of fluid from where the drug is going into your body, please tell your nurse.

The most common side effects of Onvinc 1mg Injection are hair loss, constipation, headache, peripheral neuropathy (tingling and numbness of feet and hand), stomach cramps, feeling tired or weak, back, bone, joint or muscle pain, mouth irritation or mouth sores​​​​​​​. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently. 

Onvinc 1mg Injection is a vesicant (irritant) and can damage the tissues and blood vessels if it is not administered correctly, which can be fatal. So, it should be given by a trained professional in the hospital.

Yes, Onvinc 1mg Injection is a cytotoxic (toxic to living cells) medicine. So, it is advised to be very cautious while taking Onvinc 1mg Injection.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

Avoid consumption of alcohol while taking Onvinc 1mg Injection as it may increase drowsiness.

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Pregnancy

Unsafe

Onvinc 1mg Injection is a pregnancy category D drug. It should not be used in pregnancy as it is known to cause fetal damage. Also, maintain a gap of 6 months between the last dose of Onvinc 1mg Injection and your next pregnancy.

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Breast Feeding

Unsafe

Onvinc 1mg Injection is known to pass through breast milk and it may cause harm to the baby. So, it is advised not to breastfeed while taking Onvinc 1mg Injection.

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Driving

Unsafe

Onvinc 1mg Injection may cause weakness, dizziness and drowsiness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

The safety and efficacy of Onvinc 1mg Injection are not known in children. It should be taken only if prescribed by a doctor.

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Keep Refrigerated. Do not freeze.

About Onvinc 1mg Injection

Onvinc 1mg Injection belongs to a class of drugs known as 'anti-cancer medication,' primarily used to treat various types of cancer. It is used to treat cancer of the breast, pancreas, kidney, blood, bone, lung. Cancer is a genetic change in which our cells divide uncontrollably and spread into surrounding tissues. There are more than 100 types of cancer, including blood cancer, lung cancer, breast cancer.

Onvinc 1mg Injection contains Vincristine, which is primarily used to treat cancer. It works by blocking the replication of DNA (genetic material) in the cancer cells. Hence, this stops the further growth and multiplication of the cancer cells. 

Take Onvinc 1mg Injection as prescribed by your doctor. You are advised to take Onvinc 1mg Injection for as long as your doctor has prescribed it for you, depending upon your medical condition. In some cases, you may experience hair loss, constipation, headache, peripheral neuropathy (tingling and numbness of feet and hand), stomach cramps, feeling tired or weak, back, bone, joint, or muscle pain, mouth irritation, or mouth sores. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently. 

Do not take Onvinc 1mg Injection if you are allergic to Onvinc 1mg Injection or any of its ingredients. Onvinc 1mg Injection is a pregnancy category D drug, so it should not be used in pregnant women or if you are planning for pregnancy as Onvinc 1mg Injection causes serious congenital disabilities. You should use an effective way for birth control to avoid pregnancy (both men and women) while taking Onvinc 1mg Injection. Avoid consuming alcohol along with Onvinc 1mg Injection as it could lead to increased dizziness. Onvinc 1mg Injection may make you more susceptible to infections; consult your doctor if you develop any signs of fever, sore throat, breathlessness, jaundice, unexplained bleeding or bruising. Your doctor may advise you to undergo regular blood tests, kidney and liver tests to monitor your condition. 

Uses of Onvinc 1mg Injection

Various types of cancer

Medicinal Benefits Mweb

Medicinal Benefits

Onvinc 1mg Injection contains Vincristine, an anti-cancer medicine used to treat various types of cancer. It is used to treat cancers of the blood (leukemia or lymphomas), breast, head and neck or lung. It may be used to treat multiple myeloma (a cancer of plasma cells), and it may also be used in the treatment of some cancers in children. It is also used in a blood disorder known as idiopathic thrombocytopenic purpura (ITP) after another medication has become unsuccessful in treating it.

Directions for Use

Onvinc 1mg Injection comes in injection form. So, it should be administered by a doctor or trained professional at a hospital. Never self administer.

Side Effects of Onvinc 1mg Injection

  • Constipation
  • Headache
  • Hair loss
  • Peripheral neuropathy (tingling and numbness of feet and hand)
  • Stomach cramps
  • Feeling tired or weak
  • Mouth irritation or mouth sores
  • Back, bone, joint, or muscle pain

Drug Warnings

Do not take Onvinc 1mg Injection if you are allergic to Onvinc 1mg Injection or any of its ingredients. You should use an effective way for birth control to avoid pregnancy (both men and women) while taking Onvinc 1mg Injection. Do not take Onvinc 1mg Injection if you are pregnant or planning for pregnancy as Onvinc 1mg Injection causes serious congenital disabilities. Onvinc 1mg Injection should not be taken by breastfeeding mothers as it is not known whether it passes through breast milk or not. Talk to your doctor before taking Onvinc 1mg Injection if you have/had liver or kidney problems, ulceration in stomach or bowels, poor general condition, received any vaccinations or if are due to have any, diabetes mellitus treated with insulin. Onvinc 1mg Injection causes dizziness and drowsiness, so drive with caution. Onvinc 1mg Injection should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol along with Onvinc 1mg Injection as it could lead to increased dizziness. Onvinc 1mg Injection may make you more susceptible to infections; consult your doctor if you develop any signs of infections such as fever, sore throat, breathlessness, jaundice, unexplained bleeding or bruising. Your doctor may advise you to undergo regular blood tests, kidney and liver tests to monitor your condition. 

Drug-Drug Interactions

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VincristineThalidomide
Severe
VincristineKetoconazole
Severe

Drug-Drug Interactions

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VincristineThalidomide
Severe
How does the drug interact with Onvinc 1mg Injection:
Taking thalidomide together with Onvinc 1mg Injection may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking thalidomide and Onvinc 1mg Injection together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
VincristineKetoconazole
Severe
How does the drug interact with Onvinc 1mg Injection:
When Onvinc 1mg Injection is taken with Ketoconazole, it can increase the blood levels of Onvinc 1mg Injection which may lead to side effects.

How to manage the interaction:
Taking Ketoconazole with Onvinc 1mg Injection together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience constipation, stomach pain or bloating, difficulty urinating, numbness or tingling in hands and feet, muscle weakness, difficulty walking, hearing loss, seizures(fits), unexpected or excessive bleeding, easy bruising, paleness, fatigue, fainting, infection, fever, chills, sore throat, or other flu-like symptoms, consult the doctor. Do not discontinue any medications without a doctor's advice.
VincristineBaricitinib
Severe
How does the drug interact with Onvinc 1mg Injection:
Coadministration of Onvinc 1mg Injection with Baricitinib can increase the risk of developing serious infections.

How to manage the interaction:
Although taking Baricitinib and Onvinc 1mg Injection together can cause an interaction, it can be taken if your doctor has suggested it. However, consult a doctor if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate. Do not stop using any medications without a doctor's advice.
VincristineVoriconazole
Severe
How does the drug interact with Onvinc 1mg Injection:
Using Onvinc 1mg Injection together with voriconazole may significantly increase the blood levels and effects of Onvinc 1mg Injection.

How to manage the interaction:
Although taking Voriconazole and Onvinc 1mg Injection together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience abdominal pain, difficulty urinating, hearing loss, fever contact a doctor right away. Do not discontinue any medications without consulting a doctor.
VincristineClozapine
Severe
How does the drug interact with Onvinc 1mg Injection:
When Onvinc 1mg Injection and Clozapine are taken together, can increase the effect of Onvinc 1mg Injection.

How to manage the interaction:
Taking Clozapine with Onvinc 1mg Injection together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having any of these symptoms like fever, chills, sore throat, or muscle aches, it's important to contact your doctor right away. They may be able to recommend other options for you that won't cause any problems. Don't worry, there are solutions available to help you feel better. Do not stop using any medications without first talking to your doctor.
VincristineInfliximab
Severe
How does the drug interact with Onvinc 1mg Injection:
When Onvinc 1mg Injection is taken with Infliximab, it can lead to or increase the risk or severity of developing serious infections.

How to manage the interaction:
There may be a possibility of interaction between Infliximab and Onvinc 1mg Injection, but it can be taken if prescribed by a doctor. However, if you experience symptoms of fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in sputum, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
VincristineRitonavir
Severe
How does the drug interact with Onvinc 1mg Injection:
Taking Ritonavir and Onvinc 1mg Injection may significantly increase the blood levels and effects of Onvinc 1mg Injection.

How to manage the interaction:
Although there is a possible interaction between Onvinc 1mg Injection and Ritonavir, you can take these medicines together if prescribed by your doctor. However, if you experience constipation, abdominal pain or bloating, difficulty urinating, numbness or tingling in hands and feet, muscle weakness, difficulty walking, hearing loss, fits, unusual or excessive bleeding, easy bruising, paleness, tiredness, fainting, infection, fever, chills, sore throat contact a doctor. Do not stop using any medications without a doctor's advice.
VincristineCladribine
Severe
How does the drug interact with Onvinc 1mg Injection:
Combining Cladribine with Onvinc 1mg Injection can increase the risk and severity of developing serious infections.

How to manage the interaction:
Although taking Cladribine and Onvinc 1mg Injection together can cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms, it's important to contact a doctor right away. These symptoms include infection, fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning when you pee. Do not stop using any medications without a doctor's advice.
VincristineEtanercept
Severe
How does the drug interact with Onvinc 1mg Injection:
When Etanercept is used with Onvinc 1mg Injection, the likelihood or severity of infection may increase.

How to manage the interaction:
Although there is a possible interaction between Etanercept and Onvinc 1mg Injection, you can take these medicines together if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
VincristineCeritinib
Severe
How does the drug interact with Onvinc 1mg Injection:
Taking Onvinc 1mg Injection with Ceritinib significantly increase the blood levels and effects of Onvinc 1mg Injection which may increase the risk of side effects.

How to manage the interaction:
There may be a possibility of interaction between Onvinc 1mg Injection and Ceritinib, but it can be taken if prescribed by a doctor. If you experience any of these symptoms constipation, abdominal pain or bloating, difficulty urinating, numbness or tingling in hands and feet, muscle weakness, difficulty walking, hearing loss, fits, unusual or excessive bleeding, easy bruising, paleness, weakness, fainting, infection, fever, chills, sore throat, call a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • ISONIAZID
  • DACTINOMYCIN
  • ITRACONAZOLE
  • FLUCONAZOLE
  • ASPARAGINASE

Habit Forming

No

Special Advise

  • Regularly monitor your blood cell count, platelet count and liver function.
  • If you see any redness, pain, swelling, burning, skin sores, or leaking of fluid from where the drug is going into your body, please tell your nurse as this could mean that Onvinc 1mg Injection is not being administered properly which could lead to tissue damage.

Diet & Lifestyle Advise

  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listen to soothing music.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, and high fiber content. Also, eat small and frequent meals for a speedy recovery.
  • Avoid smoking and alcohol consumption. Also, avoid high fat and cholesterol diet.

Onvinc 1mg Injection Substitute

Substitutes safety advice
  • Vincihal 1 mg Injection 1 ml

    by Others

    54.00per tablet
  • Vincristine Gls 1 mg Injection 1's

    by Others

    54.00per tablet
  • Alcrist 1mg Injection

    by Others

    46.74per tablet
  • Biocristin AQ 1 mg Injection 1 ml

    by Others

    45.19per tablet
  • Cytocristin 1mg Injection

    by Others

    43.82per tablet
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