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  1. Home
  2. Medicine

  3. Open UP 150 Tablet 10's

Open UP 150 Tablet 10's, Pack of 10 TABLETS
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Know More

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Composition :

URSODEOXYCHOLIC ACID-150MG

Manufacturer/Marketer :

Albert David Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

BILE ACID SEQUESTRANTS

Country of origin

INDIA

Manufacturer/Marketer address

D' Block, 3rd Floor, Gillander House, Netaji Subhas Road, Kolkata - 700001 (WB)
Other Info - OPE0029

Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 8, 2025 | 9:31 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Open UP 150 Tablet works in decreasing the production of cholesterol and by dissolving the cholesterol in bile, thereby prevents the formation of gallstones. Open UP 150 Tablet decreases the toxic levels of bile acids that accumulate in primary biliary cirrhosis.

Do not discontinue Open UP 150 Tablet without consulting your doctor. To treat your condition effectually continue taking Open UP 150 Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Open UP 150 Tablet .

Diarrhoea might be a side-effect of Open UP 150 Tablet . Drink lots of fluids and eat food rich in fibre if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience excess diarrhoea consult your doctor. Do not take anti-diarrheal medicine on your own.

Avoid taking aluminium-containing antacids along with Open UP 150 Tablet as they might interfere with the absorption of Open UP 150 Tablet . Maintain a gap of 2 hours between both.

Open UP 150 Tablet might reduce the absorption of antibiotics (ciprofloxacin and dapsone) and antihypertensive agents (nitrendipine). Open UP 150 Tablet might increase the effect of immunosuppressants (cyclosporine). Cholesterol-lowering agents (clofibrate) might promote the formation of gallstones. Inform your doctor before taking Open UP 150 Tablet with other medicines to avoid unpleasant side-effects.

Oral contraceptives (oestrogen) might promote the formation of gallstones. Consult your doctor if you have any concerns regarding this, your doctor may advise other contraception methods.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Open UP 150 Tablet as it may cause increased dizziness and liver damage.

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Pregnancy

Caution

Open UP 150 Tablet belongs to pregnancy category B. Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Open UP 150 Tablet ; your doctor will decide whether Open UP 150 Tablet can be taken by breastfeeding mothers or not.

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Driving

Caution

Open UP 150 Tablet does not affect your ability to drive. However, you are advised to be cautious while driving if you experience dizziness.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Open UP 150 Tablet can be given to children with caution above 6 years and only if prescribed by the doctor.

Product Substitutes

Reference

  1. https://www.medicines.org.uk/emc/files/pil.10065.pdf
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/020675s017lbl.pdf
  3. https://medlineplus.gov/druginfo/meds/a699047.html
  4. https://www.drugs.com/mtm/ursodiol.html

About Open UP 150 Tablet

Open UP 150 Tablet belongs to a group of medicines called the biliary agents or gall stone dissolution agents used to treat gall stones, primary biliary cholangitis (an autoimmune disease of the liver), excess cholesterol in bile and children above 6years with biliary and liver diseases caused by cystic fibrosis. 

Open UP 150 Tablet contains ursodeoxycholic acid, which is a naturally-occurring bile acid. Open UP 150 Tablet helps decrease the production of cholesterol in the blood, thereby dissolving gall bladder stones composed mainly of cholesterol. Open UP 150 Tablet has a protective effect on the liver cells from injury caused due to toxic bile acids and improves liver function.

Take Open UP 150 Tablet with food. You are advised to take Open UP 150 Tablet for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as abdominal discomfort, abdominal pain, diarrhoea, nausea, rash, dizziness, indigestion and weakness. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Inform your doctor before taking Open UP 150 Tablet if you have variceal bleeding (high blood pressure in portal veins), ascites (excess abdominal fluid), liver encephalopathy or liver disease. Do not take Open UP 150 Tablet if you are pregnant or breastfeeding unless prescribed. Open UP 150 Tablet can be given to children above 6 years if prescribed by the doctor. Avoid consuming alcohol along with Open UP 150 Tablet as it could lead to increased drowsiness and liver damage. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Open UP 150 Tablet

Gall stones, primary biliary cholangitis and biliary and liver diseases caused by cystic fibrosis.

Medicinal Benefits Mweb

Medicinal Benefits

Open UP 150 Tablet contains ursodeoxycholic acid, which is a naturally-occurring bile acid. It belongs to a group of medicines called the biliary agent or gall stone dissolution agents used to treat gall stones, primary biliary cholangitis (an autoimmune disease of the liver), excess cholesterol in bile children above 6 years with biliary and liver diseases caused by cystic fibrosis. Open UP 150 Tablet breaks down the cholesterol that has formed into gall bladder stones, thereby dissolves the stones. Open UP 150 Tablet has a protective effect on the liver cells and the immune system, thereby improving liver function. Open UP 150 Tablet decreases the amount of cholesterol produced by the liver and absorbed by the intestine. In patients with primary biliary cirrhosis, Open UP 150 Tablet increases the bile flow.

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water; do not chew, or crush the tablet/capsule.Syrup/Suspension/Drops: Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper; shake the pack well before each use.Dispersible tablet: Disperse the tablet in water and consume it.

Side Effects of Open UP 150 Tablet

  • Abdominal discomfort
  • Abdominal pain
  • Diarrhoea
  • Nausea
  • Fever
  • Cough
  • Rash
  • Dizziness
  • Indigestion
  • Black or tarry stools
  • Frequent and painful urination
  • Weakness

Drug Warnings

Do not take Open UP 150 Tablet if you are allergic to any of its contents, if you have inflammation of gall bladder and bile ducts, narrowing or blockage bile ducts, biliary colic, calcified gallstones, improper constriction of the gallbladder, gastric or duodenal ulcer. Inform your doctor before taking Open UP 150 Tablet if you have variceal bleeding (high blood pressure in portal veins), ascites (excess abdominal fluid), liver encephalopathy or liver disease. Consult your doctor before taking Open UP 150 Tablet with other medicines as Open UP 150 Tablet might reduce the absorption of antibiotics (ciprofloxacin and dapsone) and antihypertensive agents (nitrendipine), increase the effect of immunosuppressants (cyclosporine), oral contraceptives (oestrogen) and cholesterol-lowering agents (clofibrate) might promote the formation of gallstones. Do not take Open UP 150 Tablet if you are pregnant or breastfeeding unless prescribed. Open UP 150 Tablet can be given to children above 6 years if prescribed by the doctor. Avoid consuming alcohol along with Open UP 150 Tablet as it could lead to increased drowsiness and liver damage. Keep your doctor informed about your health condition and medicines to rule out any unpleasant side-effects.

Drug-Drug Interactions Checker List

  • CIPROFLOXACIN
  • DAPSONE
  • CYCLOSPORINE
  • ESTROGEN
  • ALUMINUM HYDROXIDE
  • ALUMINUM CARBONATE
  • NITRENDIPINE
  • MAGALDRATE

Habit Forming

No

Special Advise

  • Your doctor may advice regular liver function test to monitor the function of the liver and the progress of the treatment.
  • Open UP 150 Tablet may rarely cause thinning and loss of hair, if there is excessive loss of hair consult your doctor for further advice.

Diet & Lifestyle Advise

  • Include foods such as bell peppers, citrus fruits, leafy vegetables, tomatoes, milk, fish, low-fat dairy, beans, nuts, lentils, tofu and tempeh in your diet.
  • Eat a healthy, well-balanced diet which includes fruits and vegetables.
  • Foods rich in Vitamin B, C and calcium, are good for gallbladder.
  • Plant-based protein foods such as beans, nuts, lentils, tofu and tempeh help prevent gallbladder disease.
  • Avoid high-fat, trans-fat and processed foods.
  • White bread, white pasta and sugars should be avoided.
  • Avoid tobacco and alcohol consumption.

Open UP 150 Tablet Substitute

Substitutes safety advice

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