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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

OXALIPLATIN-50MG

Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

CHEMOTHERAPY

Country of origin

India

Manufacturer/Marketer address

A €“ 504, Shapath-4, B/S Hotel Crowne Plaza, Opp. Karnavati Club, S. G. Highway ,Ahmedabad 380 051 Gujarat
Other Info - OXA0052

FAQs

Oxa 50 mg Injection works by killing the cancer cells. Thereby, it helps treat cancer.

Oxa 50 mg Injection may have an anti-fertility effect, which could be irreversible. Therefore, male patients should seek medical advice on the conservation of sperm prior to treatment with Oxa 50 mg Injection.

Avoid drinking or eating anything colder than room temperature. Do not touch any cold objects, wash your hands in cold water, go near air conditioners or freezers, or go outside in cold weather unless absolutely necessary for five days after you receive each dose of Oxa 50 mg Injection. Wear a hat, gloves, and a scarf, and cover your mouth and nose if you must go outside in cold weather.

Oxa 50 mg Injection may decrease the ability to fight infections due to reduced white blood cells. Stay away from sick people during treatment with Oxa 50 mg Injection.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Consult your doctor

It is not known if alcohol affects Oxa 50 mg Injection. Please consult your doctor.

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Pregnancy

Unsafe

Oxa 50 mg Injection may cause foetal harm. Therefore, avoid becoming pregnant during treatment with Oxa 50 mg Injection.

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Breast Feeding

Unsafe

Breastfeeding is not recommended during treatment with Oxa 50 mg Injection and for three months after the last dose.

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Driving

Caution

Oxa 50 mg Injection may cause dizziness or vision problems. Avoid driving or operating machinery if you experience any side effects that might lessen your ability to do so.

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Liver

Consult your doctor

If you have a history of liver disease, inform your doctor before receiving Oxa 50 mg Injection.

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Kidney

Caution

Oxa 50 mg Injection should not be used if you have severe kidney disease. If you have mild or moderate kidney disease, inform your doctor before receiving Oxa 50 mg Injection.

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Children

Unsafe

Oxa 50 mg Injection is not recommended for children as safety and effectiveness have not been established.

About Oxa 50 mg Injection

Oxa 50 mg Injection belongs to the group of medicines called platinum-containing antineoplastic agents used alone or in combination with other anti-cancer medicines to treat cancer of the large bowel/intestine (advanced colon or colorectal cancer). 
 
Oxa 50 mg Injection contains Oxaliplatin, which works by killing the cancer cells. Thereby, it helps treat cancer.
 
In some cases, Oxa 50 mg Injection may cause side effects such as mild nausea, vomiting, diarrhoea, fever, and headache. Most of these side effects may not require medical attention and resolve gradually over time. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.
 
Do not use Oxa 50 mg Injection if you are breastfeeding. Consult a doctor immediately if you become pregnant during treatment with Oxa 50 mg Injection. This medicine is not recommended for children as safety and effectiveness have not been established. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Oxa 50 mg Injection

Colon and rectal cancer

Medicinal Benefits Mweb

Medicinal Benefits

Oxa 50 mg Injection contains Oxaliplatin, which belongs to the group of medicines called platinum-containing antineoplastic agents used to treat stage III colon cancer after complete removal of the primary tumour and metastatic cancer of the colon and rectum. It is used in combination with other anti-cancer medicines, such as 5-fluorouracil and folinic acid. Oxa 50 mg Injection works by killing the cancer cells. Thereby, it helps treat cancer. Oxa 50 mg Injection may also be used with other medicines to prevent colon cancer from spreading in patients who have had surgery to remove the tumour.

Directions for Use

Oxa 50 mg Injection will be administered by a qualified physician; do not self-administer.

Side Effects of Oxa 50 mg Injection

  • Mild nausea
  • Vomiting
  • Diarrhoea
  • Headache
  • Peripheral neuropathy
  • Fatigue
  • Back pain
  • Stomach pain

Drug Warnings

Do not use Oxa 50 mg Injection if you are allergic to any of its components, if you are breastfeeding, have a low blood cell count, have severe kidney problems, tingling and numbness in the fingers/toes, and have difficulty performing fragile tasks, such as buttoning clothes. Inform the doctor if you ever suffered an allergic reaction to platinum-containing medicines, have mild/moderate kidney problems, liver problems or abnormal liver function tests during therapy, or heart disorders like prolongation of the QT interval (abnormal electrical signal), an irregular heartbeat, or a family history of heart problems. Seek immediate medical attention if you experience symptoms of an allergic reaction (rash, itching, hives, reddening of the skin, hoarseness, difficulty breathing or swallowing, feeling as if your throat is closing, dizziness, swelling of the lips and tongue, lightheadedness, or fainting), unpleasant sensation in the throat, rhabdomyolysis (muscle pain and swelling), nerve problems (sensitivity to cold temperature or cold objects, pain, tingling or burning sensation), Posterior Reversible Encephalopathy Syndrome (headache, confusion, seizures, vision problems), myelosuppression (chills or shivering, burning or pain on urination, pain on swallowing, sore throat, cough with mucus, persistent diarrhoea), lung problems (shortness of breath, wheezing, cough), or bleeding problems (vomit that looks like coffee grounds or bloody vomit, pink or brown urine, weakness, dizziness, changes in speech, confusion, unexplained bleeding or dark-coloured/tarry stools).

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Oxa 50 mg Injection 25 ml:
Combining Oxa 50 mg Injection 25 ml with Ziprasidone can increase the risk of QTc prolongation.

How to manage the interaction:
Taking Oxa 50 mg Injection 25 ml with Ziprasidone is not recommended, please consult your doctor before taking it.
How does the drug interact with Oxa 50 mg Injection 25 ml:
Co-administration of Oxa 50 mg Injection 25 ml with Clozapine can increase the risk of neutropenia (low white blood count).

How to manage the interaction:
Although taking Oxa 50 mg Injection 25 ml and Clozapine together can evidently cause an interaction, it can be taken if a doctor has suggested it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Oxa 50 mg Injection 25 ml:
Taking Oxa 50 mg Injection 25 ml with ceritinib can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although there is a interaction between Oxa 50 mg Injection 25 ml and Ceritinib, but it can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
How does the drug interact with Oxa 50 mg Injection 25 ml:
Coadministration of Amiodarone together with Oxa 50 mg Injection 25 ml may raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Even though Amiodarone and Oxa 50 mg Injection 25 ml interact, they can be used if prescribed by a doctor. If you have cardiac problems or electrolyte imbalances, you may be at greater risk. If you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, get medical attention. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Oxa 50 mg Injection 25 ml:
Taking Tofacitinib with Oxa 50 mg Injection 25 ml may increase the risk of infection.

How to manage the interaction:
Although taking Oxa 50 mg Injection 25 ml and Tofacitinib together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without talking to your doctor.
How does the drug interact with Oxa 50 mg Injection 25 ml:
Using Moxifloxacin together with Oxa 50 mg Injection 25 ml can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Oxa 50 mg Injection 25 ml and Moxifloxacin, you can take these medicines together if prescribed by a doctor. However, consult the doctor immediately if you experience dizziness, shortness of breath, or heart palpitations (irregular heartbeat). Do not stop using any medications without a doctor's advice.
How does the drug interact with Oxa 50 mg Injection 25 ml:
Co-administration of Oxa 50 mg Injection 25 ml with mifepristone can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Oxa 50 mg Injection 25 ml with mifepristone together is avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Oxa 50 mg Injection 25 ml:
When Etanercept is used with Oxa 50 mg Injection 25 ml, the likelihood or severity of infection may increase.

How to manage the interaction:
Although there is a possible interaction between Oxa 50 mg Injection 25 ml and Etanercept, you can take these medicines together if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Oxa 50 mg Injection 25 ml:
Co-administration of Oxa 50 mg Injection 25 ml and Haloperidol can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Co-administration of Oxa 50 mg Injection 25 ml and Haloperidol can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Oxa 50 mg Injection 25 ml:
Using ivabradine together with Oxa 50 mg Injection 25 ml can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is a possible interaction between Oxa 50 mg Injection 25 ml and Ivabradine, you can take these medicines together if prescribed by your doctor. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Habit Forming

No

Special Advise

  • Women must use reliable contraception during treatment and for nine months after receiving the last dose.
  • Male patients are advised not to father a child during treatment and for six months after the last dose. Use effective contraception during this time.
  • If you are due to undergo any surgery, including dental surgery, inform the doctor/dentist that you are on treatment with Oxa 50 mg Injection.
  • Avoid eating or drinking anything that is colder than room temperature for five days after receiving each dose of Oxa 50 mg Injection. To reduce side effects caused by cold temperature-cover yourself with a blanket while getting treatment with Oxa 50 mg Injection, wear warm clothing in cold weather at all times, cover your mouth and nose with a scarf and wear gloves whilst touching cold objects. Drink fluid at room/warm temperature and always drink through a straw. Avoid using ice and AC, touching cold metals, and breathing deeply when exposed to cold air.

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include vegetables and fruits in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep; rest well.
  • Drink enough water and eat fibre-rich foods, vegetables and fruits.

Oxa 50 mg Injection Substitute

Always consult your doctor before taking any new medications and supplements

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