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Author Details
_0.jpg?tr=q-85,f-webp,w-100,dpr-1,c-at_max "Santoshini Reddy G")
Drug-Drug Interactions
Severe
ParacetamolValdecoxib
Severe
Drug-Drug Interactions
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Severe
How does the drug interact with PA 12 mg Tablet:
Co-administration of PA 12 mg Tablet may decrease the excretion rate of Oxazepam which could result in a higher serum level.
How to manage the interaction:
Although there is a possible interaction between Oxazepam and PA 12 mg Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
Co-administration of PA 12 mg Tablet may decrease the excretion rate of Oxazepam which could result in a higher serum level.
How to manage the interaction:
Although there is a possible interaction between Oxazepam and PA 12 mg Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolValdecoxib
Severe
How does the drug interact with PA 12 mg Tablet:
Co-administration of PA 12 mg Tablet and Valdecoxib may increase the risk or severity of adverse effects.
How to manage the interaction:
Although there is a possible interaction between PA 12 mg Tablet and Valdecoxib, you can take these medicines together if prescribed by a doctor. However, if the side effects worsen, please consult a doctor.
Co-administration of PA 12 mg Tablet and Valdecoxib may increase the risk or severity of adverse effects.
How to manage the interaction:
Although there is a possible interaction between PA 12 mg Tablet and Valdecoxib, you can take these medicines together if prescribed by a doctor. However, if the side effects worsen, please consult a doctor.
ParacetamolLomitapide
Severe
How does the drug interact with PA 12 mg Tablet:
Co-administration of Lomitapide and PA 12 mg Tablet may increase the risk of severity of liver injury.
How to manage the interaction:
Although there is a possible interaction between PA 12 mg Tablet and Lomitapide, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
Co-administration of Lomitapide and PA 12 mg Tablet may increase the risk of severity of liver injury.
How to manage the interaction:
Although there is a possible interaction between PA 12 mg Tablet and Lomitapide, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with PA 12 mg Tablet:
Co-administration of ketamine and PA 12 mg Tablet may decrease the effectiveness of Ketamine which could result in a higher blood level.
How to manage the interaction:
Although taking Ketamine and PA 12 mg Tablet together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you're feeling very sleepy or having trouble breathing, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.
Co-administration of ketamine and PA 12 mg Tablet may decrease the effectiveness of Ketamine which could result in a higher blood level.
How to manage the interaction:
Although taking Ketamine and PA 12 mg Tablet together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you're feeling very sleepy or having trouble breathing, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with PA 12 mg Tablet:
Co-administration of Teriflunomide with PA 12 mg Tablet may increase the risk or severity of Liver problems.
How to manage the interaction:
Taking PA 12 mg Tablet with Teriflunomide together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
Co-administration of Teriflunomide with PA 12 mg Tablet may increase the risk or severity of Liver problems.
How to manage the interaction:
Taking PA 12 mg Tablet with Teriflunomide together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with PA 12 mg Tablet:
Co-administration of PA 12 mg Tablet and Leflunomide may increase the risk of liver problems.
How to manage the interaction:
Although there is a possible interaction between PA 12 mg Tablet and Leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Co-administration of PA 12 mg Tablet and Leflunomide may increase the risk of liver problems.
How to manage the interaction:
Although there is a possible interaction between PA 12 mg Tablet and Leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with PA 12 mg Tablet:
Co-administration of PA 12 mg Tablet and Ketoconazole may increase the risk of liver injury.
How to manage the interaction:
Although there is a possible interaction between PA 12 mg Tablet and Ketoconazole, you can take these medicines together if prescribed by a doctor. However, if you have joint pain or swelling, fever, chills, unusual bleeding or bruising, skin rash, itching, over-tiredness, nausea, vomiting, loss of appetite, stomach pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact a doctor immediately as these may be signs and symptoms of liver damage. Do not discontinue the medication without consulting a doctor.
Co-administration of PA 12 mg Tablet and Ketoconazole may increase the risk of liver injury.
How to manage the interaction:
Although there is a possible interaction between PA 12 mg Tablet and Ketoconazole, you can take these medicines together if prescribed by a doctor. However, if you have joint pain or swelling, fever, chills, unusual bleeding or bruising, skin rash, itching, over-tiredness, nausea, vomiting, loss of appetite, stomach pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact a doctor immediately as these may be signs and symptoms of liver damage. Do not discontinue the medication without consulting a doctor.
ParacetamolMipomersen
Severe
How does the drug interact with PA 12 mg Tablet:
Co-administration of Mipomersen with PA 12 mg Tablet may increase the risk or severity of liver injury.
How to manage the interaction:
There may be a possibility of interaction between PA 12 mg Tablet and Mipomersen, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
Co-administration of Mipomersen with PA 12 mg Tablet may increase the risk or severity of liver injury.
How to manage the interaction:
There may be a possibility of interaction between PA 12 mg Tablet and Mipomersen, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
Drug-Food Interactions
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.
Drug-Food Interactions
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Drug-Diseases Interactions
PARACETAMOL-1000MGMental and behavioural disorders due to use of alcohol
Severe
PARACETAMOL-1000MGHepatic failure, not elsewhere classified
Severe
Drug-Diseases Interactions
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PARACETAMOL-1000MGMental and behavioural disorders due to use of alcohol
Severe
How does the disease interact with PA 12 mg Tablet:
Chronic alcoholics may have a higher risk of hepatotoxicity when using PA 12 mg Tablet. Patients using PA 12 mg Tablet may cause severe liver damage, including acute liver failure that required a liver transplant and resulted in death.
How to manage the interaction:
PA 12 mg Tablet should be used with caution in patients who consume three or more alcoholic drinks a day. Avoid alcohol consumption while taking PA 12 mg Tablet. If you have nausea, vomiting, fever, rash, anorexia (eating disorder), over-tiredness, upper right stomach pain, dark urine, and jaundice, contact your doctor as these may be signs and symptoms of liver injury.
Chronic alcoholics may have a higher risk of hepatotoxicity when using PA 12 mg Tablet. Patients using PA 12 mg Tablet may cause severe liver damage, including acute liver failure that required a liver transplant and resulted in death.
How to manage the interaction:
PA 12 mg Tablet should be used with caution in patients who consume three or more alcoholic drinks a day. Avoid alcohol consumption while taking PA 12 mg Tablet. If you have nausea, vomiting, fever, rash, anorexia (eating disorder), over-tiredness, upper right stomach pain, dark urine, and jaundice, contact your doctor as these may be signs and symptoms of liver injury.
PARACETAMOL-1000MGHepatic failure, not elsewhere classified
Severe
How does the disease interact with PA 12 mg Tablet:
The liver predominantly converts PA 12 mg Tablet to inactive forms. Patients with hepatic impairment may be more prone to toxicity because their minor metabolic pathways are more active.
How to manage the interaction:
PA 12 mg Tablet should be used with caution in patients with kidney insufficiency. Also, it is recommended to avoid drinking alcohol while taking PA 12 mg Tablet.
The liver predominantly converts PA 12 mg Tablet to inactive forms. Patients with hepatic impairment may be more prone to toxicity because their minor metabolic pathways are more active.
How to manage the interaction:
PA 12 mg Tablet should be used with caution in patients with kidney insufficiency. Also, it is recommended to avoid drinking alcohol while taking PA 12 mg Tablet.
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