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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Consume Type :

ORAL

Return Policy :

Not Returnable

Therapeutic Class

GASTROINTESTINAL AGENTS

Country of origin

India
Other Info - PA10911

Author Details

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FAQs

Paboriv E 30mg/40mg Tablet SR contains Esomeprazole and Domperidone. Esomeprazole works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid. Domperidone works by increasing the movements and contractions of stomach muscles. Together, Paboriv E 30mg/40mg Tablet SR helps in treating acidity.

Diarrhoea might be a side-effect of Paboriv E 30mg/40mg Tablet SR. Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if you experience excessive diarrhoea or if you find blood in your stools.

Avoid lying down immediately after meals to prevent acid reflux. Raise the head of the bed 10-20cm by putting a pillow so that the head and chest are above the waist. This helps in preventing acid reflux.

Dry mouth could be a side-effect of Paboriv E 30mg/40mg Tablet SR. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help stimulate saliva and thereby prevent drying of the mouth.

Paboriv E 30mg/40mg Tablet SR contains domperidone which helps in treating nausea and vomiting by increasing the movements and contractions of stomach muscles.

Do not take Paboriv E 30mg/40mg Tablet SR for longer durations unless prescribed by the doctor. Consult your doctor if your condition does not improve even after taking Paboriv E 30mg/40mg Tablet SR for 14days.

Paboriv E 30mg/40mg Tablet SR should not be taken along with HIV medicines such as atazanavir, ritonavir, nelfinavir, and saquinavir as Paboriv E 30mg/40mg Tablet SR might affect their absorption. Consult your doctor before taking Paboriv E 30mg/40mg Tablet SR with other medicines to avoid unpleasant side-effects.

On long-term treatment, Paboriv E 30mg/40mg Tablet SR might increase the risk of bone fracture in the spine, wrist or hip. Inform your doctor if you have osteoporosis or if you are taking corticosteroids, as they can increase the risk of bone fractures.

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Paboriv E 30mg/40mg Tablet SR. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.

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Pregnancy

Caution

Consult your doctor before taking Paboriv E 30mg/40mg Tablet SR if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Paboriv E 30mg/40mg Tablet SR; your doctor will decide whether Paboriv E 30mg/40mg Tablet SR can be taken by breastfeeding mothers or not.

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Driving

Caution

Paboriv E 30mg/40mg Tablet SR may cause dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed. Consult your doctor before taking Paboriv E 30mg/40mg Tablet SR if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Consult your doctor before taking Paboriv E 30mg/40mg Tablet SR if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Paboriv E 30mg/40mg Tablet SR should not be given to children as safety and effectiveness were not established.

About Paboriv E 30mg/40mg Tablet SR

Paboriv E 30mg/40mg Tablet SR belongs to a group of gastrointestinal agents used to treat gastroesophageal reflux disease (GERD), Zollinger-Ellison syndrome, and stomach ulcers. The stomach is usually protected from acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets eroded, which leads to complications like GERD, acidity, peptic ulcers and Zollinger-Ellison syndrome.

Paboriv E 30mg/40mg Tablet SR is a combination of two drugs: Esomeprazole (proton pump inhibitor) and Domperidone (a dopamine antagonist). Esomeprazole works by blocking an enzyme called gastric proton pump, which is responsible for the production of acid Domperidone works by increasing the movements and contractions of stomach muscle. Together, Paboriv E 30mg/40mg Tablet SR helps in treating acidity-related problems.

You are advised to take Paboriv E 30mg/40mg Tablet SR for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as dry mouth, stomach pain, diarrhoea, headache, and flatulence. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Consult your doctor before taking Paboriv E 30mg/40mg Tablet SR if you are pregnant or breastfeeding. Paboriv E 30mg/40mg Tablet SR may cause dizziness, so drive only if you are alert. Paboriv E 30mg/40mg Tablet SR should not be given to children as safety has not been established. Avoid consuming alcohol and Paboriv E 30mg/40mg Tablet SR as it could lead to increased drowsiness and elevate stomach acid production. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Paboriv E 30mg/40mg Tablet SR

Gastroesophageal reflux disease (GERD), Zollinger-Ellison syndrome, Stomach ulcers

Medicinal Benefits Mweb

Medicinal Benefits

Paboriv E 30mg/40mg Tablet SR is a combination of two drugs: Esomeprazole and Domperidone. Paboriv E 30mg/40mg Tablet SR is used to treat gastroesophageal reflux disease (GERD), Zollinger-Ellison syndrome, and stomach ulcers. It may also be indicated in the treatment of nausea, vomiting, fullness of the stomach, belching, heavy bloating, heartburn, acidity, gas, upper abdominal pain, erosive oesophagitis, and swallowing problems. Esomeprazole is a proton pump inhibitor that blocks an enzyme called gastric proton pump, responsible for acid production. Domperidone is a dopamine antagonist which works by increasing the movements and contractions of stomach muscles. Together, Paboriv E 30mg/40mg Tablet SR helps in treating acidity-related problems.

Directions for Use

Take Paboriv E 30mg/40mg Tablet SR 1 hour prior to food. Swallow Paboriv E 30mg/40mg Tablet SR as a whole with a glass of water; do not chew or crush it.

Side Effects of Paboriv E 30mg/40mg Tablet SR

  • Dry mouth
  • Stomach pain
  • Diarrhoea
  • Headache
  • Flatulence

Drug Warnings

Do not take Paboriv E 30mg/40mg Tablet SR if you are allergic to any of its contents or other proton pump inhibitors (such as pantoprazole, rabeprazole, lansoprazole or omeprazole); if you are taking nelfinavir (used to treat HIV); if you have prolactinoma (tumour of the pituitary gland), blockage in intestines, bleeding in stomach or intestine, moderate to severe liver disease, low level of potassium or magnesium or high levels of magnesium, or heart problems. Inform your doctor before taking Paboriv E 30mg/40mg Tablet SR if you have severe kidney, heart or liver disease, or if you are due to have Chromogranin A blood test; if you have fungal infections, heart problems or HIV infection. Talk to your doctor if you experience weight loss, problems with swallowing, stomach pain, indigestion, vomit food or blood, or if you pass black stools while taking Paboriv E 30mg/40mg Tablet SR. On long-term treatment, Paboriv E 30mg/40mg Tablet SR may cause low magnesium levels, vitamin B12 levels, and might increase the risk of bone fractures; the doctor may advise regular tests for monitoring your condition. Consult your doctor if you are pregnant or breastfeeding. Paboriv E 30mg/40mg Tablet SR may cause dizziness, so drive only if you are alert. Paboriv E 30mg/40mg Tablet SR should not be given to children as safety has not been established. Avoid consuming alcohol along with Paboriv E 30mg/40mg Tablet SR as it could lead to increased drowsiness and can elevate the production of stomach acid. A prolonged intake of Paboriv E 30mg/40mg Tablet SR is linked with a greater risk of Clostridium difficile-associated diarrhoea, so if you develop diarrhoea that does not improve, immediately consult a doctor. 

Drug-Drug Interactions Checker List

  • ATAZANAVIR
  • SAQUINAVIR
  • RITONAVIR
  • NELFINAVIR
  • WARFARIN
  • CLOPIDOGREL
  • KETOCONAZOLE
  • ITRACONAZOLE
  • VORICONAZOLE
  • FLUCONAZOLE
  • ERLOTINIB
  • TOREMIFENE
  • VANDETANIB
  • VINCAMINE
  • DIAZEPAM
  • PHENYTOIN
  • CILOSTAZOL
  • CISAPRIDE
  • DOLASETRON
  • TACROLIMUS
  • RIFAMPICIN
  • ERYTHROMYCIN
  • CLARITHROMYCIN
  • MOXIFLOXACIN
  • PENTAMIDINE
  • TELITHROMYCIN
  • LEVOTHYROXINE
  • METHOTREXATE
  • CITALOPRAM
  • ESCITALOPRAM
  • DIGOXIN
  • HALOFANTRINE
  • HALOPERIDOL
  • PIMOZIDE
  • SERTINDOLE
  • MEQUITAZINE
  • MIZOLASTINE
  • AMIODARONE
  • DRONEDARONE
  • QUINIDINE
  • DISOPYRAMIDE
  • DOFETILIDE
  • SOTALOL
  • DILTIAZEM
  • VERAMAPIL

Habit Forming

No

Special Advise

  • Inform your doctor before taking Paboriv E 30mg/40mg Tablet SR if you are due to have Chromogranin A blood test.
  • Paboriv E 30mg/40mg Tablet SR may cause changes in blood tests. Inform the person doing the tests that you are taking Paboriv E 30mg/40mg Tablet SR.

Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
  • Maintain a healthy weight by regular exercising.
  • Avoid lying down after eating as it causes acid reflux.
  • Avoid tight-fitting clothes as it might increase the pressure on the abdomen leading to acid reflux.
  • Practise relaxation techniques and avoid stress by doing yoga or meditation.
  • Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea and soda. 
  • Avoid sitting continuously as it may trigger acidity. Take a break of 5minutes every hour by doing brisk walking or stretching.

Paboriv E 30mg/40mg Tablet SR Substitute

Substitutes safety advice
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