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Reviewed By Sunny S , MBBS
48 Hrs returnable
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Composition :

CYCLOSPORINE-50MG

Manufacturer/Marketer :

Panacea Biotec Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

IMMUNOSUPPRESSANTS

Country of origin

INDIA

Manufacturer/Marketer address

Ambala- Chandigarh Highway, Lalru – 140501, Punjab
Other Info - PAN0072

FAQs

Panimun Bioral 50 mg Capsule acts as an immunosuppressant, which helps in reducing inflammation and prevents joint stiffness, thereby provides relief from rheumatoid arthritis.

If you miss a dose of Panimun Bioral 50 mg Capsule, take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and take the scheduled dose instead.

Diarrhoea might be a side effect of Panimun Bioral 50 mg Capsule. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Yes, the use of Panimun Bioral 50 mg Capsule may cause abnormal facial and body hair growth as a common side effect. Please consult your doctor if you have any concerns.

Panimun Bioral 50 mg Capsule is known to suppress the immune system. As a result, it increases the risk of infections and developing cancers, especially of the skin. Therefore, avoid prolonged exposure to sunlight by wearing suitable protective clothing and use sunscreen regularly.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Panimun Bioral 50 mg Capsule. It could lead to increased dizziness.

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Pregnancy

Caution

Panimun Bioral 50 mg Capsule belongs to pregnancy category C. Consult your doctor before taking Panimun Bioral 50 mg Capsule if you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Panimun Bioral 50 mg Capsule passes into breast milk. Avoid breastfeeding while taking Panimun Bioral 50 mg Capsule.

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Driving

Caution

Panimun Bioral 50 mg Capsule may cause dizziness. Drive or operate machinery only if you are alert.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Panimun Bioral 50 mg Capsule is not recommended for children as efficacy and safety have not been established.

About Panimun Bioral 50 mg Capsule

Panimun Bioral 50 mg Capsule belongs to the class of medicines called 'immunosuppressant' used to prevent organ rejection after a transplant. Also, it helps to reduce the pain/inflammation in rheumatoid arthritis conditions and in the treatment of psoriasis. Organ rejection occurs when patient’s immune system recognizes the donor organ as foreign and tries to eliminate it.

Panimun Bioral 50 mg Capsule contains 'cyclosporine' which works by suppressing the body's immune system. Thereby, prevents organ rejection. It helps decrease pain and swelling, thus providing relief from the symptoms of rheumatoid arthritis.

Take Panimun Bioral 50 mg Capsule as prescribed. You are advised to take Panimun Bioral 50 mg Capsule for as long as your doctor has prescribed it for you depending on your medical conditions. In some cases, Panimun Bioral 50 mg Capsule may cause headache, vomiting nausea, high blood pressure, loss of appetite (feeling unwell and upset stomach), and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Before taking Panimun Bioral 50 mg Capsule inform your doctor if you have any allergy, kidney disease, uncontrolled high blood pressure, or any type of cancer. Consult your doctor before taking Panimun Bioral 50 mg Capsule if you are pregnant or breastfeeding. Panimun Bioral 50 mg Capsule increases the risk of infections and skin cancer. Therefore, stay cautious and avoid prolonged exposure to sunlight. Inform your doctor about your health condition and medicines you are taking to rule out any unpleasant side effects.

Uses of Panimun Bioral 50 mg Capsule

Prevent organ rejection, Rheumatoid arthritis, psoriasis (a skin disease that causes itchy and dry patches)

Medicinal Benefits Mweb

Medicinal Benefits

Panimun Bioral 50 mg Capsule belongs to the class of medicines called 'immunosuppressant' used to prevent organ rejection after a transplant. Also, it helps to reduce the pain/inflammation in rheumatoid arthritis and is used in the treatment of severe cases of skin diseases such as eczema, psoriasis and atopic dermatitis, nephrotic syndrome (kidney disease), and eye problems such as endogenous uveitis and Behçet's uveitis. Cyclosporine works by suppressing the body's immune system. Thereby, prevents organ rejection. Also, it reduces the function of the cells that cause inflammation, especially in the joint tissues. Thereby, decreasing pain, inflammation, slowing down the joint damage and disease progression over time.

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water; do not break or chew the tablet/capsule.Oral solution: Take the prescribed dose by mouth using the measuring cup provided by the pack. Shake the pack well before use.

Side Effects of Panimun Bioral 50 mg Capsule

  • Headache
  • Vomiting
  • Nausea
  • High blood pressure
  • Loss of appetite
  • Diarrhea

Drug Warnings

Do not take Panimun Bioral 50 mg Capsule if you are allergic to any of the components. Let your doctor know before using Panimun Bioral 50 mg Capsule if you have liver or kidney problems, high blood pressure, low levels of magnesium, and high levels of potassium. Panimun Bioral 50 mg Capsule may make you more susceptible to infections; consult your doctor if you develop any signs of severe conditions such as fever, sore throat, breathlessness, jaundice, unexplained bleeding, or bruising. Before taking Panimun Bioral 50 mg Capsule inform your doctor if you have any type of cancer. Do not take Panimun Bioral 50 mg Capsule if you are pregnant or planning for pregnancy. Panimun Bioral 50 mg Capsule should not be taken by breastfeeding mothers as it passes into breast milk. Inform your doctor about your health condition and medicines to rule out any unpleasant side effects.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Panimun Bioral 50 mg Capsule:
Taking cyclosporine with cidofovir can increase the risk of kidney problems.

How to manage the interaction:
Taking Panimun Bioral 50 mg Capsule with Cidofovir is not recommended, but can be taken be together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact the doctor immediately. Do not discontinue any medications without consulting a doctor
How does the drug interact with Panimun Bioral 50 mg Capsule:
Coadministration of pitavastatin with Panimun Bioral 50 mg Capsule may significantly increase the blood levels of pitavastatin which can increase the risk of side effects such as liver problems and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Pitavastatin with Panimun Bioral 50 mg Capsule is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms like unexpected bruising or bleeding, skin rash, itching, tiredness, nausea, vomiting, yellowing of the skin or eyes, unexplained muscular pain, tenderness, or weakness, fever, dark urine, chills, joint pain, or swelling, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Panimun Bioral 50 mg Capsule:
Co-administration of Baricitinib with Cyclosporine can increase the risk of infections as well as some cancers.

How to manage the interaction:
Taking Panimun Bioral 50 mg Capsule with Baricitinib is not recommended as it can cause an interaction, but it can be taken together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Panimun Bioral 50 mg Capsule:
Combining Panimun Bioral 50 mg Capsule and Simvastatin can increase the blood levels and effects of Simvastatin. This can increase the risk of side effects such as liver damage and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Panimun Bioral 50 mg Capsule and Simvastatin together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, and yellowing of the skin or eyes, contact the doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Panimun Bioral 50 mg Capsule:
When Bosentan is taken with Cyclosporine, it may increase the risk of side effects.

How to manage the interaction:
Taking Panimun Bioral 50 mg Capsule with Bosentan is not recommended, but it can be taken if prescribed by the doctor. However, if you experience any symptoms like severe headache, nausea, or an increased heart rate, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Panimun Bioral 50 mg Capsule:
When etanercept is taken with cyclosporine, it can increase the risk of infections.

How to manage the interaction:
Although taking etanercept and Panimun Bioral 50 mg Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, contact a doctor immediately if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
CiclosporinVenetoclax
Severe
How does the drug interact with Panimun Bioral 50 mg Capsule:
Co-administration of venetoclax with Panimun Bioral 50 mg Capsule may significantly increase the blood levels and effects of venetoclax.

How to manage the interaction:
Although there is a possible interaction between venetoclax and Panimun Bioral 50 mg Capsule, they can be taken together if your doctor has prescribed them. However, contact your doctor immediately if experience any symptoms such as nausea, paleness, vomiting, diarrhea and weakness. Do not stop using any medications without talking to a doctor.
How does the drug interact with Panimun Bioral 50 mg Capsule:
The combined use of aliskiren and Panimun Bioral 50 mg Capsule can significantly increase the blood levels and effects of aliskiren, which may lead to low blood pressure, hyperkalemia (high potassium levels) in the body. High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscular paralysis, abnormal heart rhythms. If you are elderly, dehydrated, or have kidney disease, diabetes, or severe heart failure, you are more prone to develop hyperkalemia while taking these medications.

How to manage the interaction:
Taking aliskiren and Panimun Bioral 50 mg Capsule will lead to an interaction, they can be taken together if your doctor has prescribed them. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. It is advised to reduce intake of potassium-rich foods such as tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes, and potassium-containing salt substitutes.
How does the drug interact with Panimun Bioral 50 mg Capsule:
Using atazanavir with ciclosporine may increase the blood levels and effects of Panimun Bioral 50 mg Capsule

How to manage the interaction:
Although there is a interaction between Panimun Bioral 50 mg Capsule and atazanavir, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience nausea, vomiting, diarrhea, abdominal pain, dizziness, weakness, headache, shaking, fits, fever, sore throat, unusual bruising or bleeding, and increased or decreased urination. Do not discontinue any medications without consulting a doctor.
CiclosporinEdoxaban
Severe
How does the drug interact with Panimun Bioral 50 mg Capsule:
Taking edoxaban and Panimun Bioral 50 mg Capsule can significantly increase the blood levels of edoxaban.

How to manage the interaction:
Taking Panimun Bioral 50 mg Capsule with edoxaban together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience bleeding, bruising, blood in stools or urine, dizziness, severe headache, weakness, or vomiting contact a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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CYCLOSPORINE-50MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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CYCLOSPORINE-50MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consuming grapefruit and grapefruit juice while taking Panimun Bioral 50 mg Capsule can increase the effects of Panimun Bioral 50 mg Capsule. Avoid consuming grapefruit and grapefruit juice while taking Panimun Bioral 50 mg Capsule.

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • TACROLIMUS
  • AMILORIDE
  • SPIRONOLACTONE
  • ALISKIREN
  • ATORVASTATIN
  • PITAVASTATIN
  • SIMVASTATIN
  • ERYTHROMYCIN
  • AZITHROMYCIN
  • VORICONAZOLE
  • ITRACONAZOLE
  • DILTIAZEM
  • VERAPAMIL
  • DANAZOL
  • ALLOPURINOL
  • COLCHICINE
  • TELAPREVIR

Habit Forming

No

Diet & Lifestyle Advise

  • Eat foods rich in quercetin (a flavonoid) such as apples, cherries, broccoli, spinach, and blueberries.
  • Consuming food rich in probiotics helps in developing the ing immune system against allergies.
  • Limit intake of food that might trigger allergies such as dairy products, soy, eggs, and nuts.
  • Avoid consumption of foods with excess sugar as flare-up inflammation.
  • Include fruits, vegetables, whole grains, healthy fats and fish in your diet.
  • Reducing stress and maintaining a regular sleep pattern would be helpful.
  • Avoid getting in contact with harsh soaps, detergents, and rough fabrics.

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