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  3. Parextin Cr-25 Tab 10'S

Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
COD available

Online payment accepted

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Whats That

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Composition :

PAROXETINE-25MG

Manufacturer/Marketer :

Exizen Lifesciences Llp

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Parextin Cr-25 Tab

Parextin Cr-25 Tab belongs to a group of medicines called antidepressants used to treat a major depressive disorder, obsessive-compulsive disorder (OCD), panic disorder, social anxiety disorder, post-traumatic stress disorder, premenstrual dysphoria disorder and generalised anxiety disorder. Depression is a mood disorder characterised by sadness, unhappiness, anger, hopelessness or loss that interferes with a person’s daily activities.

Parextin Cr-25 Tab contains ‘Paroxetine’, which is a selective serotonin reuptake inhibitor. It works by inhibiting serotonin's reuptake, a mood-enhancing chemical messenger in the brain that communicates between brain cells. This helps increase serotonin concentrations in the nerve synapse, thereby regulating mood and treating depression and anxiety disorders.

Take Parextin Cr-25 Tab as prescribed. You are advised to take Parextin Cr-25 Tab for as long as your doctor has prescribed it for you depending on your medical condition and response to the treatment. In some cases, you may experience certain common side-effects such as insomnia (difficulty sleeping), dizziness, headache, diarrhoea, nausea, fatigue, dry mouth, loss of appetite, and sexual disturbances. You are advised to talk to your doctor if the side effects persist or worsen.

Do not take Parextin Cr-25 Tab if you are pregnant, as it may cause harm to the foetus. Consult your doctor before taking Parextin Cr-25 Tab if you are breastfeeding. Avoid driving or operating machinery as Parextin Cr-25 Tab may cause dizziness, confusion, sleepiness and blurred vision. Parextin Cr-25 Tab is not recommended for children below 18 years as the safety and effectiveness have not been established. Avoid consumption of alcohol while taking Parextin Cr-25 Tab as it may make your symptoms or side-effects worse. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Parextin Cr-25 Tab

Major depressive disorder, obsessive-compulsive disorder (OCD), panic disorder, social anxiety disorder, post-traumatic stress disorder, premenstrual dysphoric disorder, and generalised anxiety disorder.

Directions for Use

Take Parextin Cr-25 Tab in the morning with food to prevent stomach upset.Tablet/Capsule: Swallow it as a whole with a glass of water; do not chew or crush the tablet/capsule.Liquid: Take the prescribed dose/quantity using the measuring cup/dosing syringe/dropper provided by the pack; shake the bottle well before use.

Medicinal Benefits

Parextin Cr-25 Tab belongs to a group of antidepressant medicines called selective serotonin reuptake inhibitors. Parextin Cr-25 Tab is used to treat major depressive disorder, obsessive-compulsive disorder (OCD), panic disorder, social anxiety disorder, post-traumatic stress disorder, premenstrual dysphoric disorder, and generalised anxiety disorder. Parextin Cr-25 Tab works by inhibiting serotonin's reuptake by nerves, a mood-enhancing chemical messenger in the brain that communicates between brain cells. This helps increase serotonin concentrations in the nerve synapse, thereby regulating mood and treating depression and anxiety disorders. Parextin Cr-25 Tab has fewer unwanted side effects than older antidepressants and helps people recover from depression.

Storage

Store in a cool and dry place away from sunlight
Side effects of Parextin Cr-25 Tab
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Drug Warnings

Do not take Parextin Cr-25 Tab if you are allergic to any of its contents; if you are taking monoamine oxidase inhibitors (MAOI) or have taken them in the last 14 days, or if you are taking antipsychotic medicines such as thioridazine or pimozide. Consult your doctor immediately if you have suicidal thoughts, such as killing or harming yourself. Inform your doctor if you have/had epilepsy, mania, diabetes, low sodium levels in blood, glaucoma, or are undergoing treatment for severe depression called electro-convulsive therapy. Do not take Parextin Cr-25 Tab if you are pregnant, as it may cause harm to the foetus. Consult your doctor before taking Parextin Cr-25 Tab if you are breastfeeding. Avoid driving or operating machinery as Parextin Cr-25 Tab may cause dizziness, confusion, sleepiness and blurred vision. Parextin Cr-25 Tab is not recommended for children below 18 years as the safety and effectiveness have not been established. Avoid consumption of alcohol while taking Parextin Cr-25 Tab as it may make your symptoms or side-effects worse.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Parextin Cr-25 Tab:
Using tranylcypromine with Parextin Cr-25 Tab can increase the risk of side effects.

How to manage the interaction:
Taking Parextin Cr-25 Tab with Tranylcypromine is not recommended, but should be taken if advised by a doctor. However, if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Parextin Cr-25 Tab:
When Parextin Cr-25 Tab is taken with Selegiline, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Parextin Cr-25 Tab with Selegiline can possibly lead to an interaction but it can be taken if your doctor has advised it. If you notice any of these symptoms like confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramps, nausea, vomiting, diarrhea, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Parextin Cr-25 Tab:
Using Linezolid together with Parextin Cr-25 Tab can increase the risk of a serious condition called serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is a chemical that plays a role in overall wellbeing and especially a mood stabilizer).

How to manage the interaction:
Taking Parextin Cr-25 Tab with Linezolid is not recommended but should be taken if advised by a doctor. However, if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Parextin Cr-25 Tab:
Taking Furazolidone with Parextin Cr-25 Tab can increase the risk of side effects

How to manage the interaction:
Taking Parextin Cr-25 Tab with Furazolidone is not recommended, but should be taken if advised by a doctor. However, if you experience confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, or blurred vision contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Parextin Cr-25 Tab:
Using Metoclopramide with Parextin Cr-25 Tab can cause serotonin syndrome. Serotonin syndrome is a condition in which a chemical called serotonin builds up in your body, causing signs and symptoms ranging from mild (shivering and diarrhoea) to severe (muscle rigidity, fever, and seizures).

How to manage the interaction:
Taking Metoclopramide with Parextin Cr-25 Tab is not recommended, as it can possibly lead to an interaction, it can be taken if prescribed by your doctor. Do not stop using any medications without a doctor’s advice.
How does the drug interact with Parextin Cr-25 Tab:
Coadministration of Parextin Cr-25 Tab with Thioridazine can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Thioridazine with Parextin Cr-25 Tab is not recommended, but should be taken if advised by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
ParoxetineIsocarboxazid
Critical
How does the drug interact with Parextin Cr-25 Tab:
Using isocarboxazid with Parextin Cr-25 Tab can increase the risk of side effects.

How to manage the interaction:
Taking Parextin Cr-25 Tab with Isocarboxazid is not recommended, but should be taken if advised by a doctor. However, if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
ParoxetineEliglustat
Critical
How does the drug interact with Parextin Cr-25 Tab:
Coadministration of Parextin Cr-25 Tab with eliglustat can increase the risk of irregular heart rhythm

How to manage the interaction:
Although there is an interaction between Parextin Cr-25 Tab and Eliglustat, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Parextin Cr-25 Tab:
Using procarbazine together with Parextin Cr-25 Tab can increase the risk of a serious condition called the serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Parextin Cr-25 Tab with Procarbazine is not recommended, but should be taken if advised by a doctor. However, if you experience confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, or blurred vision contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Parextin Cr-25 Tab:
Combining Parextin Cr-25 Tab with Pimozide can effect the rhythm of the heart

How to manage the interaction:
Taking Parextin Cr-25 Tab with Pimozide is not recommended, but should be taken if advised by a doctor. However, if you experience chest tightness, irregular heartbeat, blurred vision and nausea contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly as it helps in improving overall health and boosts self-esteem.
  • Regularly attend therapy sessions.
  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.
  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.
  • Include foods rich in omega fatty acids such as fish, nuts, fresh fruits, vegetables and olive oils.
  • Neurotransmitters are made up of amino acids. Amino acid-rich foods such as meat, dairy products, and certain fruits and vegetables help in the proper maintenance of neurotransmitters. 
  • Complex carbohydrates help in stimulating serotonin (a feel-good neurotransmitter). These include whole grains, legumes, spinach, broccoli, oranges and pears.
  • Exercising helps in the production of the body’s natural antidepressants. It also helps in relieving stress, improving mood, boosting self-esteem, and providing restful sleep.
  • Avoid smoking and alcohol consumption.
  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

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No

Therapeutic Class

PSYCHOTHERAPEUTICS

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Parextin Cr-25 Tab works by inhibiting serotonin's reuptake by nerves, a mood-enhancing chemical messenger in the brain that communicates between brain cells. This increases serotonin concentrations in the nerve synapse, thereby helping in regulating mood.

Parextin Cr-25 Tab is used to treat anxiety disorders such as obsessive-compulsive disorder (OCD), panic disorder, social anxiety disorder, post-traumatic stress disorder, premenstrual dysphoric disorder, and generalised anxiety disorder.

Do not discontinue Parextin Cr-25 Tab without consulting your doctor as it could lead to withdrawal effects. To treat your condition effectually, continue taking Parextin Cr-25 Tab for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Parextin Cr-25 Tab ; the doctor may reduce the dose gradually.

Parextin Cr-25 Tab may cause decreased libido (sex drive), impotence (erectile dysfunction), abnormal ejaculation and problems with orgasm. Consult your doctor if you have any concerns regarding this.

Dry mouth could be a side-effect of Parextin Cr-25 Tab . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

Please consult your doctor before taking Parextin Cr-25 Tab if you have glaucoma as Parextin Cr-25 Tab might cause increased pressure in the eye.

Consult your doctor before taking Parextin Cr-25 Tab if you have diabetes as Parextin Cr-25 Tab might fluctuate blood glucose levels. Regular monitoring of blood sugar levels is advised if you are taking Parextin Cr-25 Tab . Talk to your doctor if your blood sugar levels are unstable.

People taking antidepressants such as Parextin Cr-25 Tab are more likely at risk of developing suicidal thoughts. Talk to your doctor immediately if you have thoughts of harming or killing yourself.

Consult your doctor before taking tamoxifen (used to treat cancer) along with Parextin Cr-25 Tab as Parextin Cr-25 Tab might make tamoxifen less effective.

Parextin Cr-25 Tab may cause unusual bleeding or bruising such as vomiting blood or passing blood in stools. Therefore, talk to your doctor before taking Parextin Cr-25 Tab if you have a history of bleeding disorders or if you are taking medicines that might increase the risk of bleeding such as blood thinners (warfarin), anti-psychotics (perphenazine or clozapine), tricyclic antidepressants (clomipramine), or NSAID’s (acetylsalicylic acid, ibuprofen, celecoxib, etodolac, diclofenac, meloxicam).

Drug-Drug Interactions Checker List

  • WARFARIN
  • CLOPIDOGREL
  • PERPHENAZINE
  • THIORIDAZINE
  • CLOZAPINE
  • LITHIUM
  • RISPERIDONE
  • CLOMIPRAMINE
  • MOCLOBEMIDE
  • METHYLENE BLUE
  • NORTRIPTYLINE
  • DESIPRAMINE
  • ASPIRIN
  • IBUPROFEN
  • CELECOXIB
  • ETODOLAC
  • DICLOFENAC
  • MELOXICAM
  • TRAMADOL
  • PETHIDINE
  • TAMOXIFEN
  • SUMATRIPTAN
  • FENTANYL
  • RITONAVIR
  • PHENOBARBITAL
  • PHENYTOIN
  • CARBAMAZEPINE
  • PROPAFENONE
  • FLECAINIDE
  • METOPROLOL
  • RIFAMPICIN
  • LINEZOLID
  • PRAVASTATIN
  • MIVACURIUM
  • ATOMOXETINE
  • PROCYCLIDINE
  • TRYPTOPHAN
  • FOSAMPRENAVIR
  • SUXAMETHONIUM

Special Advise

  • Close monitoring of patients taking Parextin Cr-25 Tab for suicidal behaviour is advised. Talk to your doctor immediately if you have thoughts of harming or killing yourself.

Disease/Condition Glossary

Major depressive disorder: Major depressive disorder, also known as clinical depression, is a mental health disorder characterised by a persistent and intense feeling of sadness for an extended duration of time. It mainly impacts mood, behaviour, and other physical functions, such as sleep and appetite. Symptoms include sadness, loss of interest, appetite changes, sleep problems, restlessness, lack of energy, feeling worthless or guilty, thoughts of harming oneself, difficulty in concentrating, making decisions, and thinking. The exact cause of depression is unknown. However, factors such as stress, changes in hormone levels, alcohol or drug abuse, abuse during childhood, certain medical conditions and medications might increase the risk of developing depression. 

Obsessive-Compulsive Disorder (OCD): It is a mental disorder that is associated with repetitive thoughts (obsessions) and the urge to do things over and again (compulsions). Symptoms include fear of germs or the need to arrange objects in a specific manner.

Panic disorder: It is a type of anxiety disorder that causes panic attacks. In this condition, a person experiences a sudden feeling of fear, when, in reality, there is no danger. Symptoms include fast heartbeat, breathing difficulty, chest or stomach pain, weakness or dizziness, and sweating.

Social anxiety disorder: It is a chronic mental health condition that causes extreme fear, anxiety, embarrassment, and self-consciousness in social gatherings. Symptoms include excessive fear, worry about humiliation or embarrassment, concern about offending someone, and fear about being judged. 

Post-traumatic stress disorder (PTSD): It is a disorder that is characterised by failure to recover after witnessing or experiencing a terrifying event. This condition may last for a few months or years with triggers that could bring back the memories of trauma accompanied by intense physical and emotional reactions. Symptoms include nightmares, flashbacks, anxiety or depressed mood, heightened reactivity to a stimulus, and avoidance of situations that can bring back trauma. 

Generalised anxiety disorder: It is a mental health disorder characterised by feelings of anxiety, worry or fear that are strong enough to interfere with one’s daily activities. Anxiety is the body’s natural response to stress, in which the feeling of fear may be intense and debilitating. It is the most common form of emotional disorder and can affect anyone at any age. Symptoms of anxiety include rapid breathing, increased heart rate, restlessness, trouble concentrating, and difficulty falling asleep.

Premenstrual dysphoric disorder: It is a severe form of premenstrual syndrome, which includes physical and behavioural symptoms that usually resolve after the period's onset. Premenstrual dysphoric disorder causes extreme mood shifts that can disrupt work and relationships. Symptoms include irritability, anger, hopelessness, sadness, bloating, and breast tenderness.

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