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  1. Home
  2. OTC

  3. P-Cool Cream 20 gm

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About P-Cool Cream

P-Cool Cream is a combination medicine used to treat pain and bleeding associated with anal fissures and haemorrhoids (piles). An anal fissure is a small tear in the mucosa that lines the anus. Haemorrhoids, also known as piles, are the inflamed and swollen veins in the rectum and anus that cause pain, discomfort, and bleeding.
 
P-Cool Cream is a combination of three drugs, namely: Calamine (anti-pruritic), phenylephrine (sympathomimetic agent), and lidocaine (local anaesthetic). Calamine has antiseptic and anti-pruritic properties. Phenylephrine decreases swelling by shrinking the blood vessels in the affected area. Lidocaine blocks the pain signals from the nerves to the brain, thereby decreases the sensation of pain. 
 
In some cases, you may experience certain common side-effects such as burning sensation, irritation, itching and redness at the application site. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Let your doctor know if you are using prescription/nonprescription drugs and herbal products before starting P-Cool Cream. If you are known to be allergic to any of the components in P-Cool Cream, please inform your doctor. Consult your doctor before using P-Cool Cream if you are pregnant or breastfeeding. P-Cool Cream should not be used in children unless prescribed by a doctor. 

Uses of P-Cool Cream

Piles and anal fissures

Medicinal Benefits

P-Cool Cream is a combination of three drugs, namely: Calamine, phenylephrine, and lidocaine. P-Cool Cream is used to treat pain and bleeding associated with anal fissures, external or internal haemorrhoids (piles), post-haemorrhoidectomy pain (pain after operation done to remove piles), and minor degrees of proctitis (inflammation of the rectum). Calamine has antiseptic and anti-pruritic properties. Phenylephrine is a sympathomimetic agent which decreases swelling by shrinking the blood vessels in the affected area. Lidocaine is a local anaesthetic that blocks the pain signals from the nerves to the brain, thereby decreasing the pain sensation.

Directions for Use

Clean and dry the affected area. Take the prescribed amount onto the applicator and apply it to the rectal area.

Storage

Store in a cool and dry place away from sunlight

Side Effects of P-Cool Cream

  • Burning sensation
  • Irritation
  • Itching
  • Redness

Drug Warnings

Do not use P-Cool Cream if you are allergic to any of its components. Inform your doctor if you have high blood pressure, diabetes, thyroid problems, porphyria, fits, heart, kidney, or liver problems. Consult your doctor if you are pregnant or breastfeeding. Let your doctor know if you are using prescription/nonprescription drugs or herbal products before starting P-Cool Cream.

Drug Interactions

Drug-Drug Interactions: No interactions found/established.

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: No interactions found/established.

Habit Forming

No

Diet & Lifestyle Advise

  • Eat fiber-rich food and drink plenty of fluids. This helps to keep the stools soft.
  • A warm bath helps in easing pain and itching.
  • Keep your bottom dry and clean.
  • Regular exercise is recommended.
  • Avoid or limit alcohol and caffeinated products to prevent constipation.
  • Empty your bowels whenever your body tells you to.
  • Avoid pushing too hard while pooping as it can cause tearing of tissues.
  • Include vegetables, fruits, and whole wheat grains in your diet.

Special Advise

  • Clean and dry the affected area before using P-Cool Cream.
  • If P-Cool Cream comes in contact with eyes, nose, or mouth, rinse with water immediately.
  • Wash your hands before and after using P-Cool Cream.

Disease/Condition Glossary

Piles: Hemorrhoids, also known as piles, are the inflamed and swollen veins in the rectum and anus that cause pain, discomfort, and bleeding. Haemorrhoids can be external or internal. Internal haemorrhoids develop within the rectum and anus, whereas external haemorrhoids develop outside of the anus region. Piles cause pain, itching and bleeding. They also cause trouble in sitting. Symptoms include itching, irritation, pain around the anus, swelling near the anus region, painful bowel movements, and blood in stools.

Anal fissure: Anal fissure is a small tear in the mucosa that lines the anus. This causes pain and bleeding during or after a bowel movement. Anal fissures generally heal on their own. If the condition lasts for more than 8 weeks, it can be considered chronic. Sometimes surgery may also be needed depending on the condition. Symptoms include tear of skin around the anus region, burning sensation, pain, and blood during bowel movement.

Consult Doctor

About P-Cool Cream

P-Cool Cream is a combination medicine used to treat pain and bleeding associated with anal fissures and haemorrhoids (piles). An anal fissure is a small tear in the mucosa that lines the anus. Haemorrhoids, also known as piles, are the inflamed and swollen veins in the rectum and anus that cause pain, discomfort, and bleeding.
 
P-Cool Cream is a combination of three drugs, namely: Calamine (anti-pruritic), phenylephrine (sympathomimetic agent), and lidocaine (local anaesthetic). Calamine has antiseptic and anti-pruritic properties. Phenylephrine decreases swelling by shrinking the blood vessels in the affected area. Lidocaine blocks the pain signals from the nerves to the brain, thereby decreases the sensation of pain. 
 
In some cases, you may experience certain common side-effects such as burning sensation, irritation, itching and redness at the application site. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Let your doctor know if you are using prescription/nonprescription drugs and herbal products before starting P-Cool Cream. If you are known to be allergic to any of the components in P-Cool Cream, please inform your doctor. Consult your doctor before using P-Cool Cream if you are pregnant or breastfeeding. P-Cool Cream should not be used in children unless prescribed by a doctor. 

P-Cool Cream 20 gm, Pack of 1 CREAM
P-Cool Cream 20 gm, Pack of 1 CREAM
Non returnable*
Know More
COD available

Online payment accepted

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Composition :

CALAMINE-5%W/W + LIDOCAINE-3%W/W + PHENYLEPHRINE-0.1%W/W

Manufacturer/Marketer :

Group Pharmaceuticals Ltd

Consume Type :

RECTAL

Return Policy :

Not Returnable

Expires on or after :

Country of origin

India

Manufacturer/Marketer address

No. 159- B, 22nd Cross Street PIPDIC INDUSTRIAL ESTATE, PIPDIC Industrial Estate,, Mottoupalayam, Pondicherry-605009, India
Other Info - PCO0001

FAQs

P-Cool Cream contains calamine, phenylephrine and lidocaine. Calamine has antiseptic and anti-pruritic properties. Phenylephrine decreases swelling by shrinking the blood vessels in the affected area. Lidocaine blocks the pain signals from the nerves to the brain, thereby decreases the sensation of pain.

P-Cool Cream should not be used for longer durations unless prescribed by a doctor. If your condition does not improve despite using P-Cool Cream for a week, consult your doctor, he/she may prescribe you an alternate medicine.

No, P-Cool Cream should not be used on the face or any other body parts. It is intended to treat pain and bleeding in case of piles and anal fissures.

The symptoms of anal fissures and piles are similar. However, an anal fissure is a small tear in the mucosa that lines the anus, whereas piles are the inflamed and swollen veins in the rectum and anus that cause discomfort, pain, and bleeding.

To treat your condition effectually, continue using P-Cool Cream for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while using P-Cool Cream.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

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Alcohol

Caution

It is not known whether P-Cool Cream interacts with alcohol. Please consult your doctor.

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Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Breast Feeding

Caution

Please consult your doctor if you have any concerns regarding this; your doctor will decide whether P-Cool Cream can be used by breastfeeding mothers or not.

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Driving

Safe if prescribed

P-Cool Cream does not affect your ability to drive.

bannner image

Liver

Caution

Please consult your doctor if you have a liver impairment or any concerns regarding this.

bannner image

Kidney

Caution

Please consult your doctor if you have any concerns regarding the usage of P-Cool Cream in patients with kidney impairment.

bannner image

Children

Caution

Please consult your doctor if you have any concerns regarding the usage of P-Cool Cream in children.

Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Sureshvarma D

Reviewed By

Sureshvarma D

MPharma

Last Updated

Jul 8, 2025 | 9:39 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.drugs.com/mtm/calamine-topical.html
  2. https://www.drugs.com/mtm/phenylephrine-rectal.html
  3. https://www.nhs.uk/medicines/lidocaine-for-piles-and-itchy-bottom/

Uses of P-Cool Cream

Piles and anal fissures

Medicinal Benefits

P-Cool Cream is a combination of three drugs, namely: Calamine, phenylephrine, and lidocaine. P-Cool Cream is used to treat pain and bleeding associated with anal fissures, external or internal haemorrhoids (piles), post-haemorrhoidectomy pain (pain after operation done to remove piles), and minor degrees of proctitis (inflammation of the rectum). Calamine has antiseptic and anti-pruritic properties. Phenylephrine is a sympathomimetic agent which decreases swelling by shrinking the blood vessels in the affected area. Lidocaine is a local anaesthetic that blocks the pain signals from the nerves to the brain, thereby decreasing the pain sensation.

Directions for Use

Clean and dry the affected area. Take the prescribed amount onto the applicator and apply it to the rectal area.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not use P-Cool Cream if you are allergic to any of its components. Inform your doctor if you have high blood pressure, diabetes, thyroid problems, porphyria, fits, heart, kidney, or liver problems. Consult your doctor if you are pregnant or breastfeeding. Let your doctor know if you are using prescription/nonprescription drugs or herbal products before starting P-Cool Cream.

Therapeutic Class

ANORECTAL PREPARATIONS

Drug-Drug Interactions

verifiedApollotooltip
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Diet & Lifestyle Advise

  • Eat fiber-rich food and drink plenty of fluids. This helps to keep the stools soft.
  • A warm bath helps in easing pain and itching.
  • Keep your bottom dry and clean.
  • Regular exercise is recommended.
  • Avoid or limit alcohol and caffeinated products to prevent constipation.
  • Empty your bowels whenever your body tells you to.
  • Avoid pushing too hard while pooping as it can cause tearing of tissues.
  • Include vegetables, fruits, and whole wheat grains in your diet.

Habit Forming

No

Special Advise

  • Clean and dry the affected area before using P-Cool Cream.
  • If P-Cool Cream comes in contact with eyes, nose, or mouth, rinse with water immediately.
  • Wash your hands before and after using P-Cool Cream.

Disease/Condition Glossary

Piles: Hemorrhoids, also known as piles, are the inflamed and swollen veins in the rectum and anus that cause pain, discomfort, and bleeding. Haemorrhoids can be external or internal. Internal haemorrhoids develop within the rectum and anus, whereas external haemorrhoids develop outside of the anus region. Piles cause pain, itching and bleeding. They also cause trouble in sitting. Symptoms include itching, irritation, pain around the anus, swelling near the anus region, painful bowel movements, and blood in stools.

Anal fissure: Anal fissure is a small tear in the mucosa that lines the anus. This causes pain and bleeding during or after a bowel movement. Anal fissures generally heal on their own. If the condition lasts for more than 8 weeks, it can be considered chronic. Sometimes surgery may also be needed depending on the condition. Symptoms include tear of skin around the anus region, burning sensation, pain, and blood during bowel movement.

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