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Reviewed By Sunny S , MBBS
48 Hrs returnable
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Composition :

DOXYCYCLINE-100MG

Manufacturer/Marketer :

Cardeon Formulations Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTI- BACTERIALS

Country of origin

India

Manufacturer/Marketer address

No. 28 Sundar Industrial Estate,N.T.Y Layout Mysore Road , Bangalore - 560026, India
Other Info - PEP0136

FAQs

Pepdox 100 Capsule being an antibiotic prevents the growth of bacterial cells (the bad ones!) by preventing the formation of the outer protein layer of bacteria (cell wall) responsible for bacteria's growth and multiplication. It is a broad-spectrum antibiotic, i.e. it acts against various bacteria. It is a bacteriostatic antibiotic, i.e. it stops bacteria growth but does not kill them.

No, Pepdox 100 Capsule should not be stopped even if you feel better as it is an antibiotic medication and completing the full course if very necessary, otherwise the infection might re-appear in a more severe form and will also become difficult to treat due to antibiotic resistance.

The expiration date of any drug is the last day the manufacturer takes a guarantee of the full potency of the drug. Pepdox 100 Capsule should not be taken after its expiry date as it can cause kidney damage if taken after its expiry.

If you are taking Pepdox 100 Capsule , avoid taking antacids containing aluminium, calcium or magnesium or other drugs containing these cations; oral zinc, iron salts or bismuth preparations within 2 hours of consumption of Pepdox 100 Capsule as they may affect the absorption of Pepdox 100 Capsule from the stomach. Avoid taking dairy products within 2 hours of taking Pepdox 100 Capsule as they also impair the absorption of Pepdox 100 Capsule .

Acohol may reduce the effect of Pepdox 100 Capsule . It is therefore advisable to avoid drinking any alcohol while you are taking Pepdox 100 Capsule .

Use of Pepdox 100 Capsule during tooth development (last half of pregnancy, infancy, and childhood to the age of 8 years) may cause permanent staining of teeth (yellow-grey-brown). So, it is not recommended for pregnant women, breastfeeding mothers, and children below 8 years of age.

Yes. Intake of Pepdox 100 Capsule may increase your skin sensitivity to the sun rays or ultraviolet lights. So, it is better to apply any sunscreen lotions on your skin whenever you step out of your home.

Yes. Intake of Pepdox 100 Capsule may lead to overgrowth of fungal skin infections like candida. This happens because Pepdox 100 Capsule also kills good or beneficial bacteria that protect against thrush. If such symptoms occur reach out to your doctor.

Pepdox 100 Capsule generally does not affect any contraception, including the birth control pill and emergency contraceptive pills. However, if you develop vomiting or have diarrhoea, your birth control pill may not protect you from pregnancy. Please consult your doctor if you have any concerns regarding using the Pepdox 100 Capsule .

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

Pepdox 100 Capsule should not be taken until prescribed if you are taking alcohol. Keep your doctor informed if you drink alcohol.

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Pregnancy

Unsafe

Pepdox 100 Capsule is a Pregnancy Category D. There are no adequate and well-controlled studies on the use of doxycycline in pregnant women. In some cases, taking Pepdox 100 Capsule during pregnancy may affect tooth and bone development in the unborn baby. So, if you are pregnant or planning for pregnancy contact the doctor before using a Pepdox 100 Capsule .

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Breast Feeding

Caution

Pepdox 100 Capsule is excreted in the breast milk however, the extent of absorption of Pepdox 100 Capsule , by the breastfed infant is not known. Hence, the nursing mother before using a Pepdox 100 Capsule should contact the doctor.

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Driving

Safe if prescribed

The effect of doxycycline on the ability to drive or operate heavy machinery has not been fully studied but there is no evidence to suggest that doxycycline may affect the ability to drive. Discuss with your doctor if you have any concerns or are having unusual sleepiness or drowsiness after taking Pepdox 100 Capsule .

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Liver

Caution

Pepdox 100 Capsule to be taken with caution, especially if you have a history of liver diseases/conditions. Dose may have to be adjusted by your doctor.

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Kidney

Safe if prescribed

At the recommended doses, Pepdox 100 Capsule is safe to use in patients with kidney disease and no dose adjustment is warranted. If prescribed by a doctor, Pepdox 100 Capsule can be safely used. But it is best to discuss with your doctor if you have a known kidney disease/condition.

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Children

Unsafe

Use of Pepdox 100 Capsule during tooth development in infants and children below 8 years of age may cause permanent staining of teeth (yellow-grey-brown). So, it is not recommended for children below 8 years of age.

About Pepdox 100 Capsule

Pepdox 100 Capsule belongs to a group of medications called tetracycline antibiotics, used to treat bacterial infections. Pepdox 100 Capsule treats urinary tract infections, intestinal infections, respiratory infections, eye infections, sexually transmitted infections (like gonorrhoea, syphilis), gum infections, diseases (like periodontitis), and others. Besides this, Pepdox 100 Capsule also treats acne-like lesions caused by rosacea. However, it does not treat facial redness caused by rosacea. 

Pepdox 100 Capsule being an antibiotic prevents the growth of bacterial cells (the bad ones!) by preventing the formation of the outer protein layer of bacteria (cell wall) responsible for bacteria's growth and multiplication. It is a broad-spectrum antibiotic, i.e. it acts against various bacteria. It is a bacteriostatic antibiotic, i.e. it stops bacteria growth but does not kill them.

Pepdox 100 Capsule should only be taken if advised by your doctor. It can be taken with or without food but should be consumed at a fixed time for the best results. You should complete the course of Pepdox 100 Capsule as your doctor prescribes for better results. Some common side effects of Pepdox 100 Capsule are nausea (feeling or being sick), vomiting, diarrhoea etc. Please consult your doctor if these side effects become troublesome.

Pepdox 100 Capsule is pregnancy category D (high risk) medicines, so its use in pregnant and nursing mothers is not recommended. Use of Pepdox 100 Capsule during tooth development (last half of pregnancy, infancy, and childhood up to the age of 8 years) may cause teeth staining (yellow-grey-brown). Do not consume alcohol as it may cause excessive drowsiness when taken along with Pepdox 100 Capsule . Before using Pepdox 100 Capsule , tell your doctor if you ever had an allergy to Pepdox 100 Capsule , have kidney problems, liver problems, swollen food pipe (esophagitis) or muscle disease (myasthenia gravis). Please do not drink alcohol with Pepdox 100 Capsule as it may increase the unpleasant side effects like drowsiness and dizziness. 

Uses of Pepdox 100 Capsule

Bacterial infections

Medicinal Benefits Mweb

Medicinal Benefits

Pepdox 100 Capsule is a type of tetracycline class of antibiotic which is effective against a wide range of bacteria, including gram-negative, gram-positive bacteria, anaerobes, and some parasites. It is prescribed for treating various bacterial infections of the respiratory tract (influenza, pneumonia), genitourinary area (syphilis, gonorrhoea), anthrax infection, sinuses, eye, and skin. Besides this, it is also indicated in the tick-borne infections (typhus fever) caused by the Rickettsia group of bacteria like typhus fever. Off-label, usage includes the prophylaxis or prevention of malaria in the prone area and the treatment of acne. Sometimes your doctor might prescribe you Pepdox 100 Capsule as an alternative medicine to penicillin when penicillin is contraindicated.

Directions for Use

Tablet/capsule: Swallow it as a whole with water; do not crush, break or chew it.Dispersible Tablet: Check the label for directions before use. Disperse the tablet in the prescribed amount of water and swallow the contents. Do not crush, chew or swallow as a whole.

Side Effects of Pepdox 100 Capsule

  • Nausea (feeling sick)
  • Vomiting
  • Diarrhoea

Drug Warnings

Iron and antacid (like magnesium hydroxide and aluminium hydroxide) may bind to Pepdox 100 Capsule in the gastrointestinal tract, lowering its efficiency. So, a gap of at least 2 hours should be maintained between intake of Pepdox 100 Capsule and iron supplements and antacids. Prolonged use of Pepdox 100 Capsule during tooth development (last half of pregnancy, infancy, and childhood to the age of 8 years) may cause permanent discolouration of the teeth (yellow-grey-brown). Besides this, in some cases, the use of Pepdox 100 Capsule causes antibiotic-associated diarrhoea. Pepdox 100 Capsule may cause sensitive skin to sunlight and ultraviolet rays, causing an exaggerated sunburn reaction. Hence it is advisable to apply sunscreen before going outside. Its use has also been associated with an increased risk of fungal skin infections like (vaginal candidiasis - thrush). Tetracycline and Pepdox 100 Capsule can form a stable calcium complex in bone-forming tissue, thereby affecting the growth of fibula bones in young children and bone development in the foetus. Using a Pepdox 100 Capsule with isotretinoin should be avoided as it has been reported to cause pseudotumor cerebri (increased pressure inside the brain). Long-term use of Pepdox 100 Capsule may affect your blood, kidney, and liver health, so yearly diagnostics test of these parameters is recommended. Pepdox 100 Capsule  does not completely prevent malaria caused by P. falciparum as a Pepdox 100 Capsule is given only for the prophylactic regimen (protection) whenever anyone enters a malaria-prone area.

Drug-Drug Interactions

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DoxycyclineTretinoin
Critical
DoxycyclineAcitretin
Critical

Drug-Drug Interactions

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DoxycyclineTretinoin
Critical
How does the drug interact with Pepdox 100 Capsule:
Coadministration of Tretinoin with Pepdox 100 Capsule can increase the risk of side effects like vision problems.

How to manage the interaction:
Taking Tretinoin with Pepdox 100 Capsule is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden headache, nausea, vomiting, and visual disturbances, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
DoxycyclineAcitretin
Critical
How does the drug interact with Pepdox 100 Capsule:
Coadministration of Acitretin with Pepdox 100 Capsule can increase the risk and severity of vision problems.

How to manage the interaction:
Taking Acitretin with Pepdox 100 Capsule together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience headaches, nausea, vomiting, and visual disturbances, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DoxycyclineEtretinate
Critical
How does the drug interact with Pepdox 100 Capsule:
Taking Pepdox 100 Capsule with etretinate may increase the risk of vision problems.

How to manage the interaction:
Taking Etretinate with Pepdox 100 Capsule is not recommended, but can be taken if prescribed by a doctor. However, consult a doctor if you experience headache, nausea, vomiting, and visual disturbances. Do not discontinue any medication without consulting a doctor.
DoxycyclineIsotretinoin
Critical
How does the drug interact with Pepdox 100 Capsule:
Taking isotretinoin with Pepdox 100 Capsule may increase the risk of a rare condition called pseudotumor cerebri (increased pressure in the brain).

How to manage the interaction:
Although taking isotretinoin and Pepdox 100 Capsule together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as headache, nausea, vomiting, and visual disturbances, consult a doctor. Do not stop using any medications without consulting doctor.
DoxycyclineLomitapide
Severe
How does the drug interact with Pepdox 100 Capsule:
Coadministration of lomitapide with Pepdox 100 Capsule can increase the risk of liver problems.

How to manage the interaction:
There may be a possibility of interaction between Pepdox 100 Capsule and Lomitapide, but it can be taken if prescribed by a doctor. However, contact your doctor if you experience fever, chills, joint pain, swelling, skin rash, itching, feeling tired, feeling sick, stomach ache, and dark urine. Do not stop using any medications without first talking to your doctor.
DoxycyclineRetinol (vit a)
Severe
How does the drug interact with Pepdox 100 Capsule:
Taking vitamin A with Pepdox 100 Capsule may increase the risk of vision problems.

How to manage the interaction:
Although taking Retinol (vitamin A) together with Pepdox 100 Capsule can possibly result in an interaction, they can be taken together if prescribed by your doctor. Do not discontinue using any medications without consulting your doctor.
DoxycyclineAminolevulinic acid
Severe
How does the drug interact with Pepdox 100 Capsule:
Co-administration of aminolevulinic acid with Pepdox 100 Capsule may increase the risk of sunburn.

How to manage the interaction:
Co-administration of Pepdox 100 Capsule with Aminolevulinic acid can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice that your skin is very sensitive to sunlight or if you have a sunburn, it's important to contact your doctor right away. Do not stop using any medications without first talking to your doctor.
DoxycyclineSodium citrate
Severe
How does the drug interact with Pepdox 100 Capsule:
Coadministration of Sodium Citrate with Pepdox 100 Capsule can reduce the effectiveness of Pepdox 100 Capsule.

How to manage the interaction:
Although taking Sodium Citrate with Pepdox 100 Capsule can possibly result in decreased efficacy, they can be taken together if prescribed by a doctor. It is advised to separate sodium citrate and Pepdox 100 Capsule by three to four hours. Do not stop using any medications without consulting a doctor.
DoxycyclineKetoconazole
Severe
How does the drug interact with Pepdox 100 Capsule:
Coadministration of Ketoconazole and Pepdox 100 Capsule may increase the risk of liver problems.

How to manage the interaction:
Although taking Pepdox 100 Capsule with Ketoconazole can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience any symptoms such as joint pain or swelling, skin rash, itching, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not discontinue using any medications without consulting a doctor.
DoxycyclineFerrous fumarate
Severe
How does the drug interact with Pepdox 100 Capsule:
Taking Pepdox 100 Capsule with ferrous fumarate can reduce the levels and effects of Pepdox 100 Capsule.

How to manage the interaction:
Although taking ferrous fumarate and Pepdox 100 Capsule possibly results in an interaction, they can be taken together as advised by your doctor. However, consult a doctor if you experience any unusual symptoms. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • ACITRETIN
  • ISOTRETINOIN
  • WARFARIN
  • DIGOXIN
  • PHENYTOIN
  • CARBAMAZEPINE
  • BISMUTH SUBSALICYLATE

Habit Forming

No

Special Advise

  • Pepdox 100 Capsule is preferably taken empty stomach or 1-2 hours before meals but it can lead to stomach upset. To avoid this, you may take Pepdox 100 Capsule with meals but ensure you drink plenty of water to keep yourself hydrated.
  • To prevent throat irritation take Pepdox 100 Capsule in an upright position. Do not lie down for at least 30 minutes of taking it. 
  • Even if you feel better after taking Pepdox 100 Capsule , do not stop taking it until your doctor says so. This might cause the symptoms to reappear and will make the infection difficult to treat due to antibiotic resistance.
  • Pepdox 100 Capsule can affect growing teeth, so it should be avoided during pregnancy and in children less than 8 years old.
  • Pepdox 100 Capsule should not be consumed beyond its expiry date as after that it breaks down into harmful chemicals which can damage the kidney.
  • Make sure you drink plenty of fluids when you are sick. This will in general help you clear out the infection faster, protect you from dehydration, and will help you overcome some unpleasant side effects of taking Pepdox 100 Capsule .
  • Wear sunglasses and sunscreen when you go out in the sun as Pepdox 100 Capsule can make your skin sensitive to light.

Diet & Lifestyle Advise

  • It would be best to take probiotics after taking the full course of Pepdox 100 Capsule to restore some healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria which helps stimulate their growth. Thus fibre foods may help restore healthy gut bacteria after taking a course of antibiotics. Whole grains like whole-grain bread, and brown rice, should be included in your diet.
  • Avoid taking too much calcium enriched foods and drinks as it might affect the working of Pepdox 100 Capsule .
  • Avoid intake of alcoholic beverages with Pepdox 100 Capsule as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the Pepdox 100 Capsule in fighting off infections.

Pepdox 100 Capsule Substitute

Substitutes safety advice
  • Doxy T 100 Capsule 8's

    by AYUR

    4.50per tablet
  • Minicycline Capsule 10's

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    3.11per tablet
  • Codox Capsule 10's

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    3.11per tablet
  • Nudoxy Capsule 10's

    by Others

    3.28per tablet
  • Doxyday Capsule 8's

    by AYUR

    6.20per tablet
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