Pepsigard-P Suspension belongs to a class of medication called gastrointestinal agents used to treat duodenal ulcers, nausea, and vomiting. Duodenal ulcer is a peptic ulcer that develops in the duodenum (first part of the small intestine) due to erosion of the stomach's protective lining. Nausea is a feeling of uneasiness in the stomach that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth.

Pepsigard-P Suspension is a combination of two drugs: Sucralfate (gastrointestinal protectant) and Domperidone (antinausea agent). Sucralfate belongs to the protectants class which forms a protective layer over the ulcer and protects the stomach from an ulcer due to excess stomach acid, thereby healing it. Domperidone belongs to the dopamine antagonist class that works by blocking dopamine receptors that stimulate the vomiting center (chemoreceptor trigger zone – CTZ) located in the brain. Together they prevent ulcers, nausea, and vomiting.

Take Pepsigard-P Suspension as prescribed by your doctor. You are advised to take Pepsigard-P Suspension for as long as your doctor has prescribed it for you based on your medical condition. You may experience dry mouth, diarrhea, constipation, drowsiness, dizziness, or headache in some cases. Most of these side effects of Pepsigard-P Suspension do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Pepsigard-P Suspension or any other medicines, please tell your doctor. Pepsigard-P Suspension is not recommended for children below 18 years and those weighing less than 35 kg as the safety and effectiveness were not established. If you are pregnant or breastfeeding, please inform your doctor before taking $your name. Drive only if you are alert as Pepsigard-P Suspension may cause drowsiness or dizziness. Avoid alcohol consumption as it may increase adverse effects or irritate the stomach lining. Avoid taking Pepsigard-P Suspension if you have black, tarry stools or notice blood in stools as these might be signs of bleeding in the stomach or intestines.

Pepsigard-P Suspension is a combination of two drugs: Sucralfate and Domperidone used to treat duodenal ulcers, nausea, and vomiting. Sucralfate is a protectant that forms a protective layer over the ulcer and protects the ulcer from stomach acid. Thereby, it allows healing. Domperidone is a dopamine antagonist that works by blocking dopamine receptors that stimulate the vomiting center (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting. Also, domperidone acts as a prokinetic agent that increases muscle movements and contractions in the stomach. Thereby prevents vomiting and reduces bloating, nausea and fullness. 

If you are allergic to Pepsigard-P Suspension or any other medicines, please tell your doctor. Pepsigard-P Suspension is not recommended for children below 18 years and those weighing less than 35 kg as the safety and effectiveness were not established. If you are pregnant or breastfeeding, please inform your doctor before taking Pepsigard-P Suspension . If you have a prolactinoma (tumor of the pituitary gland), kidney, liver, or heart problems, diabetes, high potassium levels in the blood, or black tarry stools, inform your doctor before taking Pepsigard-P Suspension . Drive only if you are alert as Pepsigard-P Suspension may cause drowsiness or dizziness. Avoid alcohol consumption as it may increase adverse effects or irritate the stomach lining. If you experience heart rhythm disorders like difficulty in breathing, loss of consciousness, or palpitations (strong or irregular heartbeat) while taking Pepsigard-P Suspension , contact your doctor immediately. You are not recommended to take antacids such as cimetidine and sodium bicarbonate with Pepsigard-P Suspension simultaneously as it may affect the absorption of Pepsigard-P Suspension . Avoid taking Pepsigard-P Suspension if you have black, tarry stools or notice blood in stools as these might be signs of bleeding in the stomach or intestines.

• Pepsigard-P Suspension may increase the risk of cardiac arrest and heart rhythm disorder, especially in the elderly aged over 60 years, when taken with other medicines.
• If you experience heart rhythm disorders like difficulty in breathing, loss of consciousness or palpitations (strong or irregular heartbeat) while taking Pepsigard-P Suspension , contact your doctor immediately.