Perindosyl-Am 4/5Mg Tablet belongs to the class of 'anti-hypertensive drugs', primarily used to treat hypertension (high blood pressure). Hypertension is a medical condition, in which the blood exerts high pressure (force exerted by circulating blood) against blood vessel's walls. This condition makes the heart work harder in pumping the blood to the whole body. Hypertension can cause severe health complications, including stroke, heart failure, heart attack and kidney failure.

Perindosyl-Am 4/5Mg Tablet is a combination of medicine that consists of Amlodipine (calcium channel blocker) and Perindopril (angiotensin-converting enzyme inhibitor). Amlodipine belongs to the class of 'calcium channel blockers' and is used to treat high blood pressure, Prinzmetal's or variant angina (chest pain) and other conditions caused by coronary artery disease. It relaxes blood vessels, so that blood passes through them easily, thereby lowering the blood pressure. It also improves blood supply to the heart muscle to receive more oxygen and thus preventing chest pain. On the other hand, Perindopril is an angiotensin-converting enzyme (ACE) inhibitor, it reduces increased blood pressure by blocking a naturally occurring substance known as angiotensin II (that tightens your blood vessels). It relaxes and widens the blood vessels. This lowers your blood pressure and makes it easier for your heart to pump blood around your body. Thus, collectively, both help lower high blood pressure, reducing heart attack or stroke chances. 

Take Perindosyl-Am 4/5Mg Tablet as prescribed by your doctor. You are advised to take Perindosyl-Am 4/5Mg Tablet for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience ankle swelling, tiredness, headache, palpitations (irregular heartbeat), sleepiness, the increased potassium level in the blood, cough, flushing (sense of heat in the face, ears, neck, and trunk), Taste change, decreased blood pressure, and upset stomach.

Do not stop taking Perindosyl-Am 4/5Mg Tablet without consulting your doctor since it may worsen your condition and increase the risk of future heart problems. If you have angioedema (Painless swelling under the skin), diabetes then inform your doctor immediately. If you have kidney disease, you may not use Perindosyl-Am 4/5Mg Tablet with aliskiren (other blood pressure-lowering pills). Reducing the amount of table salt (sodium chloride) in your food. Immediately contact your doctor if you have heart disease, kidney disease, liver disease, and high potassium level in your blood. If you are pregnant or breastfeeding, please tell your doctor so that the dosage of Perindosyl-Am 4/5Mg Tablet can be prescribed accordingly.

Perindosyl-Am 4/5Mg Tablet treats hypertension (high blood pressure) and consists of Amlodipine (calcium channel blocker) and Perindopril (angiotensin-converting enzyme inhibitor). Amlodipine is a 'calcium channel blocker' and treats high blood pressure, Prinzmetal's or variant angina (chest pain), and other conditions caused by coronary artery disease. It relaxes blood vessels, so that blood passes through them easily, thereby lowering the blood pressure. It also treats chest pain by improving blood supply to the heart muscle to receive more oxygen. Amlodipine also improves a person's tolerance to exercise and keeps the blood pressure at acceptable levels. On the other hand, Perindopril is an angiotensin-converting enzyme (ACE) inhibitor, it reduces increased blood pressure by blocking a naturally occurring substance known as angiotensin II (that tightens your blood vessels). It relaxes and widens the blood vessels. This lowers your blood pressure and makes it easier for your heart to pump blood around your body. However, Perindosyl-Am 4/5Mg Tablet does not cure high blood pressure (hypertension) but does help control it. In addition to this, Perindosyl-Am 4/5Mg Tablet also reduces the physical effects of anxiety.

Do not stop taking Perindosyl-Am 4/5Mg Tablet without consulting your doctor since it may worsen your condition and increase the risk of future heart problems. If you have angioedema (Painless swelling under the skin), diabetes then inform your doctor immediately. If you have kidney disease, you may not use Perindosyl-Am 4/5Mg Tablet with aliskiren (other blood pressure-lowering pills). Reducing the amount of table salt (sodium chloride) in your food.  Avoid potassium, containing food. Immediately contact your doctor if you have heart disease, kidney disease, liver disease, diabetes, and high potassium level in your blood. If you are pregnant or breastfeeding, please tell your doctor so that the dosage of Perindosyl-Am 4/5Mg Tablet can be prescribed accordingly.

• Monitor your blood pressure regularly and seek medical advice if you notice any drastic fluctuations.
• Perindosyl-Am 4/5Mg Tablet may affect patients with hepatic impairment, and hence it is used cautiously, and Liver function monitoring and Liver Function Tests are advised to monitor the liver enzyme changes.
• Your doctor may advise you to get a regular kidney function test, blood examinations for potassium levels and other electrolytes while using Perindosyl-Am 4/5Mg Tablet to rule out any renal impairment.
• Do not take this medicine within 36 hours before or after taking medicine that contains sacubitril (antihypertensive drug).