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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Non returnable*
COD available

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About Perinerv NT 75mg/10mg/1500mg Tablet

Perinerv NT 75mg/10mg/1500mg Tablet is a combination medicine indicated to manage neuropathic pain associated with diabetic peripheral neuropathy and postherpetic neuralgia. Neuropathic pain is a chronic progressive nerve disease that causes nerve pain due to nerve damage or a malfunctioning nervous system. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, and evoked pain (pain caused by events usually not painful).

Perinerv NT 75mg/10mg/1500mg Tablet is a combination of three drugs: Methylcobalamin (vitamin), Nortriptyline (antidepressant), and Pregabalin (anti-convulsant). Methylcobalamin is a vitamin that aids in producing myelin, a substance that protects nerve fibres and regenerates damaged nerve cells. Nortriptyline works by increasing nerve transmitters (serotonin and noradrenaline) in the brain, thereby reducing the pain messages arriving in the brain. Pregabalin reduces pain by interfering with pain messages travelling through the brain and down the spine. Together, Perinerv NT 75mg/10mg/1500mg Tablet helps to treat neuropathic pain.

Take Perinerv NT 75mg/10mg/1500mg Tablet as prescribed. Based on your medical condition, your doctor will decide the dose and duration. In some cases, Perinerv NT 75mg/10mg/1500mg Tablet may cause dizziness, sleepiness, nausea, blurred vision, peripheral oedema (swelling of the lower legs and hands), weight gain, and dry mouth. The majority of these side effects do not necessitate medical attention and will subside gradually over time. However, if you are experiencing these side effects regularly, you should consult your doctor.

Please do not take Perinerv NT 75mg/10mg/1500mg Tablet if you are allergic to any of its ingredients. Consult your doctor before taking Perinerv NT 75mg/10mg/1500mg Tablet if you are pregnant or breastfeeding. Perinerv NT 75mg/10mg/1500mg Tablet may cause drowsiness and dizziness, so drive only if you are alert. Perinerv NT 75mg/10mg/1500mg Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Perinerv NT 75mg/10mg/1500mg Tablet as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Perinerv NT 75mg/10mg/1500mg Tablet

Neuropathic pain

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Perinerv NT 75mg/10mg/1500mg Tablet is a combination of three drugs: Methylcobalamin (a form of vitamin B), Nortriptyline (antidepressant), and Pregabalin (anti-convulsant). Perinerv NT 75mg/10mg/1500mg Tablet is indicated for the management of neuropathic pain associated with diabetic peripheral neuropathy, postherpetic neuralgia, spinal cord injury, etc. Methylcobalamin aids in producing myelin, a substance that protects nerve fibres and regenerates damaged nerve cells. Nortriptyline works by increasing nerve transmitters (serotonin and noradrenaline) in the brain, thereby reducing the pain messages arriving in the brain. Pregabalin reduces pain by interfering with pain messages travelling through the brain and down the spine. Together, Perinerv NT 75mg/10mg/1500mg Tablet helps to treat neuropathic pain.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are allergic to any of the ingredients in Perinerv NT 75mg/10mg/1500mg Tablet, do not consume it. Please do not stop taking Perinerv NT 75mg/10mg/1500mg Tablet without first consulting your doctor, as this may result in withdrawal symptoms. If you are pregnant or breastfeeding, do not take Perinerv NT 75mg/10mg/1500mg Tablet unless your doctor has prescribed it. Perinerv NT 75mg/10mg/1500mg Tablet may cause drowsiness and dizziness, therefore drive only if you are alert. Perinerv NT 75mg/10mg/1500mg Tablet is not recommended for children as safety and effectiveness have not been established. Avoid drinking alcohol while taking Perinerv NT 75mg/10mg/1500mg Tablet as it may cause drowsiness and sleepiness. If you have suicidal thoughts, consult your doctor right away.

Diet & Lifestyle Advise

  • Include vitamin B and D-rich foods in your diet.
  • Cayenne pepper should be included in your diet because it can help with neuropathic pain.
  • Exercising regularly helps to improve overall health and combat pain.
  • Rest well and get plenty of rest.
  • Taking a warm bath can be very relaxing.
  • Avoid smoking and drinking alcohol.
  • Meditation and yoga can reduce stress, pain sensitivity and improve coping skills.
  • Acupuncture, by stimulating pressure points, can be beneficial.
  • Massages with essential oils can help increase circulation.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS

Author Details

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FAQs

Perinerv NT 75mg/10mg/1500mg Tablet contains Methylcobalamin, Nortriptyline, and Pregabalin. Methylcobalamin aids in producing myelin, a substance that protects nerve fibres and regenerates damaged nerve cells. Nortriptyline alters the way nerves receive pain signals, thereby decreasing pain. Pregabalin reduces pain by interfering with pain messages travelling through the brain and down the spine. Together, Perinerv NT 75mg/10mg/1500mg Tablet helps to treat neuropathic pain.

Perinerv NT 75mg/10mg/1500mg Tablet contains pregabalin. It may cause weight gain due to an increase in appetite. Maintain a healthy weight by regular exercise and following a proper diet.

Dry mouth could be a side-effect of Perinerv NT 75mg/10mg/1500mg Tablet. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

Do not stop taking Perinerv NT 75mg/10mg/1500mg Tablet without consulting your doctor, as this could result in withdrawal symptoms. Continue taking Perinerv NT 75mg/10mg/1500mg Tablet for as long as prescribed to treat your condition effectively. If you experience any difficulty while taking Perinerv NT 75mg/10mg/1500mg Tablet, do not be afraid to speak with your doctor.

Perinerv NT 75mg/10mg/1500mg Tablet is used to treat diabetic neuropathy. Diabetic neuropathy is a condition that causes nerve damage due to high blood glucose levels. It primarily affects the nerves in the legs and feet.

Perinerv NT 75mg/10mg/1500mg Tablet may cause peripheral oedema. The swelling of the hands and lower legs are known as peripheral oedema. If you experience oedema, avoid sitting or standing for extended periods. Raise your legs by laying down and placing a pillow under them.

Drug-Drug Interactions Checker List

  • DULOXETINE
  • SERTRALINE
  • ESCITALOPRAM
  • CODEINE
  • HYDROCODONE
  • MORPHINE
  • OXYCODONE
  • TRAMADOL
  • ACETAMINOPHEN
  • TOPIRAMATE
  • ALPRAZOLAM
  • ZOLPIDEM
  • DIPHENHYDRAMINE
  • CETIRIZINE
  • CYCLOBENZAPRINE
  • ONDANSETRON
  • ST JOHN'S WORT

Special Advise

Perinerv NT 75mg/10mg/1500mg Tablet contains Nortriptyline (antidepressant), which can lead to suicidal thoughts. Suicidal thoughts or behaviour should be closely monitored in people taking Perinerv NT 75mg/10mg/1500mg Tablet. If you have suicidal thoughts, don't be afraid to talk to your doctor right away.

Disease/Condition Glossary

Neuropathic pain: Neuropathic pain is caused due to damaged sensory nerves. It is caused by chronic progressive nerve disease or due to infection or injury. The pain could be intermittent or continuous, which is felt as prickling, stabbing, tingling or burning sensation. A feeling of numbness and loss of sensations is also familiar with neuropathic pain. Usually, the body sends the pain signals when there is an injury, but with neuropathic pain, the pain is not triggered by an injury. The body unpromptedly sends the pain signals. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping and evoked pain (pain caused by events usually not painful).

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