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Written By ,
Reviewed By Hari Kumar , MBBS
48 Hrs returnable
COD available

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Whats That

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Composition :

PALBOCICLIB-125MG

Manufacturer/Marketer :

Hetero Drugs Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

CHEMOTHERAPY

Country of origin

India

Manufacturer/Marketer address

2Nd Floor, 8-3-166/7/1 Erragadda, Hyderabad-500018
Other Info - PIC0199

FAQs

Piclib 125 mg Capsule works blocking proteins responsible for cell growth and division, thereby arresting the progression of cancer cells.

Do not stop taking Piclib 125 mg Capsule on your own. You are advised to take Piclib 125 mg Capsule for as long as your doctor has prescribed it for you depending on your medical condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Piclib 125 mg Capsule .

A fibroadenoma is a benign state. Piclib 125 mg Capsule is indicated only in case of cancers. Please consult your doctor in case of any concerns.

Piclib 125 mg Capsule can reduce fertility in men. Therefore, consider sperm preservation before starting Piclib 125 mg Capsule if you wish to father a child in the future. Effects on female fertility have not been established. Please consult your doctor before using Piclib 125 mg Capsule .

Piclib 125 mg Capsule may reduce white blood cell count, thereby weakening the immune system. This might increase your risk of infections. If you notice any signs or symptoms of infections, consult your doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

It is not recommended to use alcohol with Piclib 125 mg Capsule . Please consult your doctor if you have any concerns.

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Pregnancy

Unsafe

Piclib 125 mg Capsule is not recommended for use in pregnancy. Please consult your doctor if you have any concerns.

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Breast Feeding

Unsafe

Piclib 125 mg Capsule is not recommended during breastfeeding. Please consult your doctor in case of any concerns.

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Driving

Caution

Piclib 125 mg Capsule may cause tiredness and lethargy, which may affect your ability to drive. Do not drive if you experience any side effects after using Piclib 125 mg Capsule .

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Liver

Caution

Exercise caution before using Piclib 125 mg Capsule in case of established liver disease. Please consult your doctor to address any concerns.

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Kidney

Caution

Exercise caution before using Piclib 125 mg Capsule in case of established kidney disease. Please consult your doctor to address any concerns.

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Children

Unsafe

Piclib 125 mg Capsule is not recommended for use in children under 18 years of age. Please consult your doctor in case of any concerns.

About Piclib 125 mg Capsule

Piclib 125 mg Capsule belongs to the group of anti-cancer drugs used to treat certain types of breast cancer. Cancer is the uninhibited and uncontrolled growth of cells in the body. Breast cancer is cancer that forms in the cells of the breast. It can form in the lobules, ducts or tubules of the breast or in the breast tissue itself.

Piclib 125 mg Capsule contains Palbociclib that works by blocking proteins necessary for cell growth, thereby causing cell death and arresting the uncontrolled production of new cells. Thus, Piclib 125 mg Capsule is effective in controlling cancer cells from multiplying and is used in the treatment of breast cancer. 

Take Piclib 125 mg Capsule as prescribed. In some cases, Piclib 125 mg Capsule may cause certain common side effects such as weakness, loss of appetite, infections and dry skin. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist or worsen. 

It is advisable to inform the doctor if you are allergic to any of its components. Do not take Piclib 125 mg Capsule if you are pregnant or breastfeeding. Piclib 125 mg Capsule may cause tiredness, so drive only if you are alert. Piclib 125 mg Capsule is not recommended for use in children below 18years. Keep your doctor informed about your health condition and medications to rule out any interactions.

Uses of Piclib 125 mg Capsule

Breast Cancer

Medicinal Benefits Mweb

Medicinal Benefits

Piclib 125 mg Capsule is an anti-cancer drug used in the treatment of a particular type of breast cancer that is hormone receptor-positive and human epidermal growth factor receptor-2-negative. Piclib 125 mg Capsule works by blocking the production of proteins called cyclin-dependent kinase 4 and 6 that are responsible for cell growth and division. By blocking them, Piclib 125 mg Capsule nips cell growth in the bud and prevents cancer cells from spreading further. Thus, Piclib 125 mg Capsule helps treat breast cancer.

Directions for Use

Take Piclib 125 mg Capsule preferably with a meal. Swallow it as a whole with water. Do not crush, chew or break it.

Side Effects of Piclib 125 mg Capsule

  • Loss of appetite
  • Dry skin
  • Weakness
  • Infection
  • Hair loss
  • Fever
  • Inflammation of the mouth and lips

Drug Warnings

Do not take St. John's wort or grapefruit/grapefruit juice with Piclib 125 mg Capsule . It is advisable to inform the doctor if you are allergic to any of its components. Do not take Piclib 125 mg Capsule if you are pregnant or breastfeeding. Piclib 125 mg Capsule may cause tiredness, so drive only if you are alert. Piclib 125 mg Capsule is not recommended for use in children below 18years. If you experience any signs or symptoms of infections, inform your doctor. Keep your doctor informed about your health condition and medications to rule out any interactions. Consult your doctor immediately if you experience symptoms such as dry cough, chest pain, difficulty breathing or shortness of breath as it could be an indication of lung inflammation

Drug-Drug Interactions

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PalbociclibPosaconazole
Severe
PalbociclibKetoconazole
Severe

Drug-Drug Interactions

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PalbociclibPosaconazole
Severe
How does the drug interact with Piclib 125 mg Capsule:
When Piclib 125 mg Capsule is taken with Posaconazole can increase the blood levels of Piclib 125 mg Capsule.

How to manage the interaction:
Although there is an interaction between posaconazole and Piclib 125 mg Capsule, it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, diarrhea, less desire to eat, mouth sores, hair loss, weakness, pain, numbness, or tingling in the hands and feet contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PalbociclibKetoconazole
Severe
How does the drug interact with Piclib 125 mg Capsule:
Coadministration of Ketoconazole and Piclib 125 mg Capsule may increase the blood level of Piclib 125 mg Capsule.

How to manage the interaction:
Although taking Ketoconazole and Piclib 125 mg Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience nausea, vomiting, diarrhea, loss of appetite, mouth sores, hair loss, weakness, pain, numbness, or tingling in the hands and feet, more severely, consult a doctor. Without consulting a doctor, never stop taking any drugs.
PalbociclibCladribine
Severe
How does the drug interact with Piclib 125 mg Capsule:
Taking Cladribine with Piclib 125 mg Capsule can increase the risk of developing serious infections.

How to manage the interaction:
Taking Cladribine with Piclib 125 mg Capsule together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
PalbociclibMorphine
Severe
How does the drug interact with Piclib 125 mg Capsule:
Co-administration of Piclib 125 mg Capsule with Morphine may increase the blood levels and side effects of morphine.

How to manage the interaction:
Taking Morphine with Piclib 125 mg Capsule can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like trouble breathing, feeling tired, or having a cough, dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination, make sure to contact a doctor immediately. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • RITONAVIR
  • NELFINAVIR
  • SAQUINAVIR
  • LOPINAVIR
  • TELAPREVIR
  • ITRACONAZOLE
  • KETOCONAZOLE
  • VORICONAZOLE
  • POSACONAZOLE
  • CLARITHROMYCIN
  • TELITHROMYCIN
  • ABATACEPT
  • QUINIDINE
  • COLCHICINE
  • ALFENTANIL
  • FENTANYL
  • TACROLIMUS
  • CYCLOSPORINE
  • PIMOZIDE
  • ERGOTAMINE

Habit Forming

No

Special Advise

  • Discuss contraception with your doctor while taking Piclib 125 mg Capsule .
  • People on treatment with Piclib 125 mg Capsule should use additional contraception (barrier method such as condoms). Contraception should be continued 3 weeks post-treatment for women and 14 weeks post-treatment for men.
  • You may want to consider sperm storage before starting Piclib 125 mg Capsule . Seek counsel on the same from a qualified healthcare individual and/or sperm bank. 
  • Regular complete blood count monitoring is advised.

Diet & Lifestyle Advise

  • Meditation and yoga have been proven very effective in helping cancer patients maintain a healthy attitude and body.
  • Eat more lean meats, healthy fats, fruits, vegetables and whole-grain foods to give you more energy. 
  • Stay hydrated by drinking plenty of water as dehydration is often seen in cancers.
  • Taking a stroll in the garden, or spending 30 minutes of your time doing some light physical activity can be very useful. However, do not over-exert yourself if you feel too tired. 
  • Avoid smoking and alcohol consumption.

Piclib 125 mg Capsule Substitute

Substitutes safety advice
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  • Palnat 125 mg Capsule 21's

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    175.71per tablet
  • Palbo 125 mg Capsule 21's

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    239.17per tablet
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