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Pioplus 2 Tablet is a combination of three antidiabetic medicines, Metformin, Glimepiride, and Pioglitazone. It works by increasing insulin production, helping to restore your body's appropriate response to insulin, especially muscle and fatty tissues, thereby lowering your elevated blood sugar levels.
Patients with type 2 diabetes who have congestive heart failure, kidney problems, liver problems, vision problems, or diabetic ketoacidosis should not take Pioplus 2 Tablet . It is also not given to pregnant, breastfeeding, or a premenopausal woman.
Hypoglycemia refers to low blood glucose levels. Pioplus 2 Tablet may cause hypoglycemia. Hypoglycemia can occur if you miss or delay your food, drink alcohol, intense exercise, or take other antidiabetic medicine along with this medicine. So, take your medicine as advised by your doctor to avoid any unwanted effects of this medicine.
If you feel that your blood sugar levels are dropping, eat glucose tablets or chocolate immediately. This will help to increase your sugar levels instantly. So, it is always advised to carry glucose tablets or sugar candies with you.
Yes, type 2 diabetes may also occur in children. The risk increases if the child is overweight or obese.
You may experience high blood sugar, symptoms such as increased thirst and hunger, frequent urination, weight loss, delayed wound healing, and frequent infections. Consult a doctor or endocrinologist to confirm the diagnosis.
Alcohol
Caution
Alcohol may increase the risk of side-effects and worsen the condition.
Pregnancy
Unsafe
Pioplus 2 Tablet is a category C drug and may cause harmful effects to the unborn baby. So, it is used only when the benefits of this medicine outweigh the risks.
Breast Feeding
Unsafe
Pioplus 2 Tablet should not be used in breastfeeding mothers as it may get secreted in the breast milk and cause unwanted effects in the nursing babies.
Driving
Caution
Pioplus 2 Tablet may cause vision problems. So, do not drive or operate heavy machinery if you have any problems with your vision while using Pioplus 2 Tablet .
Liver
Caution
Pioplus 2 Tablet should be taken with caution in patients with liver diseases. The dose may have to be adjusted by your doctor.
Kidney
Caution
Pioplus 2 Tablet should be taken with caution especially if you have a history of kidney diseases. The dose may have to be adjusted by your doctor.
Children
Caution
Pioplus 2 Tablet is not recommended for use in children below 18 years of age.
About Pioplus 2 Tablet
Pioplus 2 Tablet belongs to the group of medications called ‘antidiabetic agents’ used in the treatment of Type 2 diabetes mellitus. Type 2 diabetes mellitus is a chronic or life-long condition in which blood sugar or glucose levels rise more than normal. It occurs when the body does not produce enough insulin (metabolizes glucose), or if produced, it cannot function properly in the body.
Pioplus 2 Tablet is a combination of three medicines, namely: Metformin, Glimepiride, and Pioglitazone. Metformin acts by decreasing liver glucose production and intestinal glucose uptake. Glimepiride acts by increasing the amount of insulin released by the pancreas. Pioglitazone works by decreasing the amount of glucose released by the liver and also by improving the sensitivity of tissues towards insulin effects.
You should take this medicine as prescribed by your doctor. You may experience side-effects of such as nausea (feeling sick), vomiting (falling sick), diarrhea, headache, stomach ache, respiratory infection, weight gain, sweating, palpitations, and vision problems. Some patients experience decline in blood sugar levels lower than normal (hypoglycemia) resulting in sweating, dizziness, headache, confusion, feeling hungry, temporary changes in vision, uneasiness, irritability, and weakness. In such cases, seek medical attention immediately.
Do not take Pioplus 2 Tablet if you are allergic to any of its contents. Do not use this medicine if you have heart failure, bladder cancer, or diabetic ketoacidosis (a complication of diabetes). Pioplus 2 Tablet may cause ‘lactic acidosis’ (accumulation of lactic acid in the blood), which requires immediate medical attention. The risk increases if you are previously diagnosed with kidney or liver diseases. Do not consume alcohol (risk of lactic acidosis) or fast for prolonged periods (risk of hypoglycemia). Also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
Uses of Pioplus 2 Tablet
Medicinal Benefits
Pioplus 2 Tablet contains Metformin, Glimepiride, and Pioglitazone. Pioplus 2 Tablet is given when single or dual therapy of hypoglycemic agents is not effective in diabetes patients. Metformin acts by decreasing liver glucose production and intestinal glucose uptake. Glimepiride acts by increasing the secretion of insulin by the pancreas. Pioglitazone works by decreasing the amount of glucose released by the liver and improving insulin sensitivity in muscle and fat.
Directions for Use
Side Effects of Pioplus 2 Tablet
Drug Warnings
Pioplus 2 Tablet should be used with caution in patients with heart diseases as it increases the risk of heart failure. Pioplus 2 Tablet may cause ‘lactic acidosis’ (buildup of lactic acid in the blood), characterized by abdominal pain, muscle cramps, vomiting, severe fatigue, and difficulty breathing. It is a life-threatening condition that requires immediate medical attention. Inform your doctor if you have any severe liver or kidney problems as their normal functioning is required to eliminate excess lactic acid from the body. Do not consume excess alcohol as it increases the risk of lactic acidosis. Pioplus 2 Tablet may lower vitamin B12 levels, so it is recommended to take blood tests regularly to identify any vitamin deficiencies.
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