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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Hari Kumar , MBBS
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

PIRFENIDONE-801MG

Manufacturer/Marketer :

Zydus Healthcare Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

MISCELLANEOUS

Country of origin

India

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.
Other Info - PIR0150

Author Details

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FAQs

Pirfetab 801 Tablet helps in reducing the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, thereby helps you breathe better.

Pirfetab 801 Tablet might make you photosensitive (sensitivity to sunlight). Avoid exposure to sunlight and sunlamps. Wear SPF 50+ sunscreen and protective clothing to reduce exposure to sunlight. Talk to your doctor if you are taking any medicines known to cause photosensitivity. If you notice any symptoms of photosensitivity, consult a doctor.

Do not discontinue Pirfetab 801 Tablet without consulting your doctor. To treat your condition effectually, continue taking Pirfetab 801 Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Pirfetab 801 Tablet .

Diarrhoea might be a side-effect of Pirfetab 801 Tablet . Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you have severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

No, avoid smoking prior to the start of the treatment and while taking Pirfetab 801 Tablet as smoking might alter the effectiveness of Pirfetab 801 Tablet .

Weight loss could occur due to loss of appetite. Maintain proper weight by eating healthy food. Your doctor might monitor your weight whilst taking Pirfetab 801 Tablet . Consult your doctor if you notice severe weight loss.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

It is not known if alcohol interacts with Pirfetab 801 Tablet . However, avoid consumption of alcohol while taking Pirfetab 801 Tablet as it may cause increased dizziness.

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Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor if you are breastfeeding; your doctor will decide whether Pirfetab 801 Tablet can be taken by breastfeeding mothers or not.

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Driving

Caution

Pirfetab 801 Tablet might cause dizziness and tiredness. Drive or operate machinery only if you are alert.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor if you have a liver impairment or any concerns regarding this. Pirfetab 801 Tablet is not recommended for patients with severe hepatic impairment.

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have kidney impairment or any concerns. Pirfetab 801 Tablet is not recommended for patients with an end-stage renal disease requiring dialysis.

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Children

Unsafe

Pirfetab 801 Tablet is not recommended for children below 18years as the safety and effectiveness has not been established.

About Pirfetab 801 Tablet

Pirfetab 801 Tablet is an anti-fibrotic medicine used to treat idiopathic pulmonary fibrosis (IPF) in adults. IPF is an irreversible disease that is marked by a progressive decline in lung function. The tissues in the lungs become swollen and scarred over time, due to which it gets difficult to breathe deeply. The scarring makes it hard for the lungs to work properly.
 
Pirfetab 801 Tablet contains ‘Pirfenidone’, which helps in reducing the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, thereby helps you breathe better. Pirfetab 801 Tablet helps in slowing down the progress of idiopathic pulmonary fibrosis. 

In some cases, you may experience certain common side effects such as nausea, tiredness, diarrhoea, indigestion, loss of appetite, headache, and photosensitivity. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult your doctor before taking Pirfetab 801 Tablet if you are pregnant or breastfeeding. Pirfetab 801 Tablet may cause tiredness and dizziness, so drive with caution. Avoid consuming alcohol with Pirfetab 801 Tablet as it could lead to increased dizziness. Pirfetab 801 Tablet is not recommended for children below 18 years as safety and effectiveness have not been established. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Pirfetab 801 Tablet

Idiopathic pulmonary fibrosis

Medicinal Benefits Mweb

Medicinal Benefits

Pirfetab 801 Tablet is an anti-fibrotic medicine used to treat idiopathic pulmonary fibrosis (IPF) in adults. Pirfetab 801 Tablet can help effectively slow the rate of lung function decline by 50%. Pirfetab 801 Tablet helps reduce the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, thereby helps you breathe better. Pirfetab 801 Tablet helps in slowing down the progress of idiopathic pulmonary fibrosis.

Directions for Use

Take Pirfetab 801 Tablet with food. Swallow Pirfetab 801 Tablet as a whole with a glass of water; do not chew or crush it.

Side Effects of Pirfetab 801 Tablet

  • Nausea
  • Tiredness
  • Diarrhoea
  • Indigestion/Stomach upset
  • Loss of appetite
  • Headache
  • Photosensitivity

Drug Warnings

Do not take Pirfetab 801 Tablet if you are allergic to any of its components; if you have a severe or end-stage liver impairment or kidney disease requiring dialysis; if you are taking fluvoxamine (anti-depressant). Inform your doctor if you are taking any medicines that might make you photosensitive, if you smoke or have kidney or liver problems. Consult your doctor before taking Pirfetab 801 Tablet if you are pregnant or breastfeeding. Pirfetab 801 Tablet may cause tiredness and dizziness, so drive with caution. Avoid consuming alcohol with Pirfetab 801 Tablet as it could lead to increased dizziness. Pirfetab 801 Tablet is not recommended for children below 18 years as safety and effectiveness have not been established.

Drug-Drug Interactions

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PirfenidoneCarbamazepine
Critical
PirfenidonePrimidone
Critical

Drug-Drug Interactions

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PirfenidoneCarbamazepine
Critical
How does the drug interact with Pirfetab 801 Tablet:
Taking Pirfetab 801 Tablet with Carbamazepine it reduces the levels and effects of Pirfetab 801 Tablet.

How to manage the interaction:
Taking Pirfetab 801 Tablet with Carbamazepine is not recommended but can be taken if prescribed by the doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
PirfenidonePrimidone
Critical
How does the drug interact with Pirfetab 801 Tablet:
Coadministration of Pirfetab 801 Tablet with primidone can reduce levels and the effects of Pirfetab 801 Tablet.

How to manage the interaction:
Although there is an interaction between Pirfetab 801 Tablet and primidone, they can be taken together if advised by your doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PirfenidonePhenobarbital
Critical
How does the drug interact with Pirfetab 801 Tablet:
When Pirfetab 801 Tablet is taken with Phenobarbital, it can decrease the effects of Pirfetab 801 Tablet.

How to manage the interaction:
Taking Pirfetab 801 Tablet with Phenobarbital is not recommended but can be taken if prescribed by the doctor. Do not discontinue any medication without consulting a doctor.
PirfenidoneRifampicin
Critical
How does the drug interact with Pirfetab 801 Tablet:
Taking Pirfetab 801 Tablet with rifampicin can reduce the levels and effects of Pirfetab 801 Tablet

How to manage the interaction:
Although there is an interaction between Pirfetab 801 Tablet and rifampicin, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PirfenidoneCiprofloxacin
Severe
How does the drug interact with Pirfetab 801 Tablet:
When ciprofloxacin is taken Pirfetab 801 Tablet, the blood levels of Pirfetab 801 Tablet may increase, which may lead to side effects.

How to manage the interaction:
Although taking ciprofloxacin and Pirfetab 801 Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you have any of the following symptoms, fever, chills, joint pain or swelling, unusual bleeding or wounds, skin rash, itching, tiredness, nausea, vomiting, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor. Do not discontinue any medications without a doctor's advice.
PirfenidoneKetoconazole
Severe
How does the drug interact with Pirfetab 801 Tablet:
Coadministration of Ketoconazole and Pirfetab 801 Tablet may increase the risk of liver damage.

How to manage the interaction:
Although taking Ketoconazole and Pirfetab 801 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of appetite, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
PirfenidoneRucaparib
Severe
How does the drug interact with Pirfetab 801 Tablet:
Taking Pirfetab 801 Tablet with Rucaparib can increase the risk or severity of its side effects such as liver disease or gastric problems.

How to manage the interaction:
Co-administration of Pirfetab 801 Tablet with Rucaparib can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of appetite, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately.
PirfenidoneEnoxacin
Severe
How does the drug interact with Pirfetab 801 Tablet:
When Enoxacin is taken with Pirfetab 801 Tablet, it can increase the levels of Pirfetab 801 Tablet, which may lead to side effects.

How to manage the interaction:
Although taking Pirfetab 801 Tablet and Enoxacin together can cause an interaction, it can be taken if your doctor has suggested it. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of appetite, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
PirfenidoneAminolevulinic acid
Severe
How does the drug interact with Pirfetab 801 Tablet:
Co-administration of Aminolevulinic acid and Pirfetab 801 Tablet may increase the risk of skin burn.

How to manage the interaction:
There may be a possibility of interaction between Pirfetab 801 Tablet and Aminolevulinic acid, but it can be taken if prescribed by a doctor. Avoid exposure of the eyes and skin to sunlight or bright indoor lights for 48 hours after treatment. Do not discontinue any medications without consulting a doctor.
PirfenidoneLeflunomide
Severe
How does the drug interact with Pirfetab 801 Tablet:
Taking Leflunomide with Pirfetab 801 Tablet may increase the risk of liver damage.

How to manage the interaction:
Co-administration of Pirfetab 801 Tablet with Leflunomide can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of appetite, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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PIRFENIDONE-801MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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PIRFENIDONE-801MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking grape fruit and its products while using Pirfetab 801 Tablet can increase the risk of side effects. Avoid grape fruit and its products during treatment with Pirfetab 801 Tablet.

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • FLUVOXAMINE
  • CIPROFLOXACIN
  • ENOXACIN
  • RIFAMPICIN
  • AMIODARONE
  • PROPAFENONE
  • OMEPRAZOLE

Habit Forming

No

Special Advise

  • Your doctor may advise liver function tests prior to the start of the treatment.
  • Regular blood tests are advised at the start of treatment with Pirfetab 801 Tablet and monthly for every 6 months, and then for every 3 months thereafter to check the liver functioning.

Diet & Lifestyle Advise

  • Watch out for triggers that make the cough worse, such as smoke, foods, air-conditioning, high altitude, etc.
  • Exercise moderately. Eat healthily.
  • Follow the pulmonary rehabilitation program. It includes exercise, disease education, and group therapy.
  • Quit smoking.
  • Get ample rest.
  • Include green leafy vegetables, sweet potatoes, broccoli, tomatoes, carrots, mangoes, citrus fruits, berries, and cocoa.
  • Lean proteins such as fish, meat, and poultry are the best.
  • Hydration is important. Drink plenty of water, herbal tea, and fruit juices.
  • Avoid processed and refined foods.

Pirfetab 801 Tablet Substitute

Substitutes safety advice
  • Pirfenex 801 Tablet 10's

    by Others

    70.20per tablet
  • Fibrodone 801 Tablet 10's

    by AYUR

    68.04per tablet
  • Pulmofib 801 Tablet 10's

    by AYUR

    65.25per tablet
  • Fiboresp Forte Tablet 10's

    by AYUR

    58.50per tablet
  • Pirfact 801 Tablet 10's

    by AYUR

    9.54per tablet
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