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  3. Posacad Oral Suspension 105 ml

Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

POSACONAZOLE-40MG

Manufacturer/Marketer :

Cadila Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTIFUNGALS

Country of origin

India

Manufacturer/Marketer address

Sarkhej-Dholka Road, Bhat, Ahmedabad-382 210, India.
Other Info - POS0108

FAQs

Posacad Oral Suspension contains a medicine called posaconazole. It is a triazole antifungal agent and exerts its antifungal activity through the blockage of certain enzymes (P-450 dependent enzyme, sterol 14α-demethylase). This leads to inhibiting the synthesis of ergosterol, a key component of the fungal cell membrane, and the accumulation of methylated sterol precursors. This results in inhibiting fungal cell growth and, ultimately, cell death. Thus, it treats infections.

Posacad Oral Suspension is not recommended for coadministration with anticoagulants, So if you are under anticoagulant therapy, inform your doctor before prescribing Posacad Oral Suspension .

If you are allergic to posaconazole or similar antifungals such as fluconazole, itraconazole, ketoconazole, or voriconazole, you should not use it. When combined with certain medications, posaconazole can have unfavourable or dangerous side effects.

Like all medicines, this medicine may cause side effects such as diarrhoea, nausea, fever, vomiting, headache, coughing and low potassium levels in the blood, although not everybody gets them. Most of these side effects of Posacad Oral Suspension do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Take Posacad Oral Suspension as prescribed by your doctor. You are advised to take Posacad Oral Suspension for as long as your doctor has prescribed it for you based on your medical condition.

Disclaimer

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Alcohol

Caution

It is unknown whether Posacad Oral Suspension alters the ability to drive, so do not drive or operate machinery if you experience any symptoms affecting your ability to concentrate and react.

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Pregnancy

Caution

Posacad Oral Suspension should not be used when pregnancy unless clearly necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Posacad Oral Suspension .

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Breast Feeding

Caution

There is no substantial research yet on using Posacad Oral Suspension in breastfeeding/nursing mothers. Inform your doctor if you are a nursing mother before taking Posacad Oral Suspension ; your doctor will decide whether Posacad Oral Suspension can be taken by breastfeeding mothers.

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Driving

Caution

It is unknown whether Posacad Oral Suspension alters the ability to drive, so do not drive or operate machinery if you experience any symptoms affecting your ability to concentrate and react.

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Liver

Caution

Inform your doctor before receiving the Posacad Oral Suspension if you have a liver impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Inform your doctor before receiving the Posacad Oral Suspension if you have a kidney impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Safe if prescribed

Your doctor will weigh the benefits and potential risks before prescribing Posacad Oral Suspension .

About Posacad Oral Suspension

Posacad Oral Suspension is in a class of medications called azole antifungals. It is used to prevent and treat fungal infections when other antifungal medicines have not worked, or you have had to stop taking them. It is also indicated for preventing invasive Aspergillus and Candida infections in patients at high risk of developing these infections due to being severely immunocompromised, such as hematopoietic stem cell transplant (HSCT) recipients with graft-versus-host disease (GVHD) or those with hematologic malignancies with prolonged neutropenia from chemotherapy.

Posacad Oral Suspension contains a medicine called posaconazole. It is a triazole antifungal agent and exerts its antifungal activity through the blockage of certain enzymes (P-450 dependent enzyme, sterol 14α-demethylase). This leads to inhibiting the synthesis of ergosterol, a key component of the fungal cell membrane, and the accumulation of methylated sterol precursors. This results in the inhibition of fungal cell growth and cell death. Thus, it treats infections.

Take Posacad Oral Suspension as prescribed by your doctor. You are advised to take Posacad Oral Suspension for as long as your doctor has prescribed it based on your medical condition. In some cases, you may experience diarrhoea, nausea, fever, vomiting, headache, coughing and low potassium levels in the blood. Most of these side effects of Posacad Oral Suspension do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Inform your doctor if you are allergic or hypersensitive to any component present in Posacad Oral Suspension or if you are pregnant, suspect you are pregnant, plan to have a baby or are breastfeeding; your doctor will prescribe Posacad Oral Suspension only if the benefits outweigh the risk. Before taking the Posacad Oral Suspension , inform your doctor about your medical history and ongoing therapies to rule out any potential adverse effects or interactions.

Uses of Posacad Oral Suspension

Fungal infectionsProphylaxis of invasive Aspergillus and Candida infections in severely immunocompromised patients.

Medicinal Benefits Mweb

Medicinal Benefits

Posaconazole is an antifungal medication present in Posacad Oral Suspension . It is effective in treating fungal infections in adults. It is also indicated for preventing invasive Aspergillus and Candida infections in patients who are severely immunocompromised and at high risk of developing these infections, such as hematopoietic stem cell transplant (HSCT) recipients with graft-versus-host disease (GVHD) or those with hematologic malignancies with prolonged neutropenia from chemotherapy.

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it.Oral Suspension/syrup: Shake the bottle well before each use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper.

Side Effects of Posacad Oral Suspension

  • Diarrhoea
  • Nausea
  • Fever
  • Vomiting
  • Headache
  • Coughing
  • Low potassium levels in the blood

Drug Warnings

Inform your doctor if you are allergic or hypersensitive to any component present in Posacad Oral Suspension or if you are pregnant, suspect you are pregnant, plan to have a baby or are breastfeeding; your doctor will prescribe Posacad Oral Suspension only if the benefits outweigh the risk. Before taking the Posacad Oral Suspension , inform your doctor about your medical history and ongoing therapies to rule out any potential adverse effects or interactions. And also, let your doctor know before prescribing Posacad Oral Suspension if you have Arrhythmias and QTc Prolongation, liver problems, or low potassium, magnesium, or calcium levels in your blood.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Posacad Oral Suspension 105 ml:
Taking atorvastatin with Posacad Oral Suspension 105 ml can increase the blood levels of atorvastatin. This can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Posacad Oral Suspension 105 ml with atorvastatin, they can be taken together if advised by your doctor. However, contact the doctor if you experience unexplained muscle pain, weakness, fever, chills, joint pain or swelling, unusual bleeding, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark coloured urine, or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Posacad Oral Suspension 105 ml:
Coadministration of Posacad Oral Suspension 105 ml with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Posacad Oral Suspension 105 ml with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Posacad Oral Suspension 105 ml:
Taking lovastatin with Posacad Oral Suspension 105 ml can increase the levels of lovastatin in the blood which can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Lovastatin and Posacad Oral Suspension 105 ml, they can be taken together if advised by a doctor. However, contact a doctor if you experience ever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Posacad Oral Suspension 105 ml:
When Posacad Oral Suspension 105 ml is taken with Cisapride, it can lower the rate at which Cisapride is broken down in the body.

How to manage the interaction:
Taking Posacad Oral Suspension 105 ml with Cisapride is not recommended, please consult your doctor before taking it. They can be taken together if advised by your doctor. However, contact your doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Posacad Oral Suspension 105 ml:
Using ivabradine together with Posacad Oral Suspension 105 ml may significantly increase the blood levels and effects of ivabradine.

How to manage the interaction:
Taking Ivabradine with Posacad Oral Suspension 105 ml together is generally not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Posacad Oral Suspension 105 ml:
When Posacad Oral Suspension 105 ml is taken with Ranolazine, may significantly increase the blood levels and effects of Ranolazine.

How to manage the interaction:
Although there is an interaction between Posacad Oral Suspension 105 ml and ranolazine, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Posacad Oral Suspension 105 ml:
When Isavuconazole is taken with Posacad Oral Suspension 105 ml, it can increase the levels of isavuconazole in the blood.

How to manage the interaction:
Although there is an interaction between isavuconazole and Posacad Oral Suspension 105 ml, it can be taken if prescribed by the doctor. However, if you experience nausea, vomiting, diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Posacad Oral Suspension 105 ml:
Taking pimozide with Posacad Oral Suspension 105 ml can increase the levels of pimozide in the blood, which can lead to an increased risk of abnormal heart rhythm.

How to manage the interaction:
Although there is an interaction between Posacad Oral Suspension 105 ml and pimozide, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience severe or prolonged diarrhea, vomiting dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Posacad Oral Suspension 105 ml:
Coadministration of silodosin and Posacad Oral Suspension 105 ml may significantly increase the blood levels and effects of silodosin.

How to manage the interaction:
Although there is an interaction between Posacad Oral Suspension 105 ml and Silodosin, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, nasal congestion, and headache. Do not discontinue any medications without consulting a doctor.
PosaconazoleConivaptan
Critical
How does the drug interact with Posacad Oral Suspension 105 ml:
When Posacad Oral Suspension 105 ml is taken with Conivaptan, it can increase the blood levels and effects of conivaptan.

How to manage the interaction:
Although there is an interaction between Posacad Oral Suspension 105 ml and conivaptan, they can be taken together if prescribed by a doctor. However, contact a doctor if you experience difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, or mood changes. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • TERFENADINE
  • ASTEMIZOLE
  • CISAPRIDE
  • PIMOZIDE
  • HALOFANTRINE
  • QUINIDINE

Habit Forming

No

Special Advise

  • Regular blood tests are recommended before and while taking Posacad Oral Suspension to monitor liver functioning, especially if you have any liver problems.

Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals if you take Posacad Oral Suspension for more than one day.
  • Do not use other over-the-counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Posacad Oral Suspension .
  • Continue taking your normal regular diet unless your doctor prescribes a specific diet.
  • It is advisable to follow a candida diet during yeast infections. This diet excludes sugar, gluten, certain dairy products, alcohol and switches to low-sugar fruits, non-starchy vegetables, and gluten-free foods.
  • A very high sugar or high-carbohydrate diet may increase the count of Candida in some people. It is better to avoid or limit alcohol and caffeine intake during Posacad Oral Suspension treatment to enhance a healthy lifestyle practice.

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