PR-Lupro Injection belongs to the class of medicines called gonadotropin-releasing hormone (GnRH) agonists primarily used to treat prostate cancer and endometriosis. Additionally, it is also used to treat precocious puberty (early puberty) in children. PR-Lupro Injection is used in combination with other medicines to treat anaemia caused by uterine fibroids.

PR-Lupro Injection contains Leuprolide acetate, which is a synthetic hormone that acts similar to the GnRH, produced by the hypothalamus gland in the brain. It works by inhibiting the synthesis of the natural male hormone, testosterone in men and oestrogen in women. This process of lowering hormone levels can decrease cancer cell growth in prostate cancer and helps treat endometriosis.

PR-Lupro Injection will be administered by a healthcare professional. The common side effects of PR-Lupro Injection include hot flashes, decreased sexual interest, dizziness, headache, nausea, vomiting, diarrhoea, upset stomach and injection site reaction. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Avoid taking PR-Lupro Injection if you are pregnant or breastfeeding. Both women and men using PR-Lupro Injection should use effective contraception. PR-Lupro Injection may affect fertility, hence discuss with your doctor if you have any plans to start a family in the future. PR-Lupro Injection is not recommended for children below two years of age. PR-Lupro Injection may cause dizziness, hence drive only if you are alert.

PR-Lupro Injection contains Leuprolide acetate, a gonadotropin-releasing hormone (GnRH) agonist. It treats prostate cancer in men, endometriosis in women and precocious puberty (early puberty) in children. PR-Lupro Injection is a synthetic hormone that acts similar to the GnRH, produced by the hypothalamus gland in the brain. PR-Lupro Injection works by lowering testosterone levels in men that help stop the growth of cancer cells in prostate cancer. PR-Lupro Injection reduces oestrogen (a hormone required for the development and regulation of the female reproductive system and secondary sexual characteristics) levels in women, thus helping in endometriosis.

If you are allergic to PR-Lupro Injection or any other medicines, please tell your doctor. PR-Lupro Injection is not indicated for use in pregnancy and breastfeeding women. If you are using PR-Lupro Injection, make sure to use reliable forms of contraception. PR-Lupro Injection may also affect fertility in men, hence discuss with your doctor if you have any plans to start a family in the future. PR-Lupro Injection is not recommended for children younger than two years of age. If you have a seizure or unusual changes in mood or behaviour, inform your doctor immediately. Before starting PR-Lupro Injection, let your doctor know if you have liver or kidney diseases, heart diseases, recent heart attack, depression, brain tumours, electrolyte imbalance, diabetes, fits, weak bones and high cholesterol levels. PR-Lupro Injection may cause QT prolongation (heart muscle takes longer than normal to recharge between beats) and may affect heart rhythm, hence heart patients should be cautious while taking PR-Lupro Injection. PR-Lupro Injection can make you feel dizzy and affects your mental ability to drive. Do not drive or operate machinery if you are not mentally alert and focused.

• Your doctor may advise liver function tests to monitor your liver health since PR-Lupro Injection may cause increased liver enzymes (alanine aminotransferase, serum aspartate and serum transaminases).
• PR-Lupro Injection may cause increased serum glucose levels (hyperglycaemia), hence inform your doctor if you have diabetes before starting PR-Lupro Injection.
• Your doctor may advise blood tests, electrolyte levels and regular examinations of the prostate.

• It is advised to get an electrocardiogram (ECG) done timely to monitor your heart health.