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  3. PR-Lupro Injection 1's

PR-Lupro Injection 1's, Pack of 1 INJECTION
Written By ,
Reviewed By Santoshini Reddy G , M Pharmacy
Non returnable*
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Composition :

LEUPROLIDE ACETATE-11.25MG

Manufacturer/Marketer :

Orca Healthcare Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About PR-Lupro Injection

PR-Lupro Injection belongs to the class of medicines called gonadotropin-releasing hormone (GnRH) agonists primarily used to treat prostate cancer and endometriosis. Additionally, it is also used to treat precocious puberty (early puberty) in children. PR-Lupro Injection is used in combination with other medicines to treat anaemia caused by uterine fibroids.

PR-Lupro Injection contains Leuprolide acetate, which is a synthetic hormone that acts similar to the GnRH, produced by the hypothalamus gland in the brain. It works by inhibiting the synthesis of the natural male hormone, testosterone in men and oestrogen in women. This process of lowering hormone levels can decrease cancer cell growth in prostate cancer and helps treat endometriosis.

PR-Lupro Injection will be administered by a healthcare professional. The common side effects of PR-Lupro Injection include hot flashes, decreased sexual interest, dizziness, headache, nausea, vomiting, diarrhoea, upset stomach and injection site reaction. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Avoid taking PR-Lupro Injection if you are pregnant or breastfeeding. Both women and men using PR-Lupro Injection should use effective contraception. PR-Lupro Injection may affect fertility, hence discuss with your doctor if you have any plans to start a family in the future. PR-Lupro Injection is not recommended for children below two years of age. PR-Lupro Injection may cause dizziness, hence drive only if you are alert.

Uses of PR-Lupro Injection

Prostate cancer, Endometriosis, Precocious puberty

Directions for Use

PR-Lupro Injection will be administered by a healthcare professional. Do not self-administer.

Medicinal Benefits

PR-Lupro Injection contains Leuprolide acetate, a gonadotropin-releasing hormone (GnRH) agonist. It treats prostate cancer in men, endometriosis in women and precocious puberty (early puberty) in children. PR-Lupro Injection is a synthetic hormone that acts similar to the GnRH, produced by the hypothalamus gland in the brain. PR-Lupro Injection works by lowering testosterone levels in men that help stop the growth of cancer cells in prostate cancer. PR-Lupro Injection reduces oestrogen (a hormone required for the development and regulation of the female reproductive system and secondary sexual characteristics) levels in women, thus helping in endometriosis.

Storage

Keep PR-Lupro Injection out of reach and sight of children.

Drug Warnings

If you are allergic to PR-Lupro Injection or any other medicines, please tell your doctor. PR-Lupro Injection is not indicated for use in pregnancy and breastfeeding women. If you are using PR-Lupro Injection, make sure to use reliable forms of contraception. PR-Lupro Injection may also affect fertility in men, hence discuss with your doctor if you have any plans to start a family in the future. PR-Lupro Injection is not recommended for children younger than two years of age. If you have a seizure or unusual changes in mood or behaviour, inform your doctor immediately. Before starting PR-Lupro Injection, let your doctor know if you have liver or kidney diseases, heart diseases, recent heart attack, depression, brain tumours, electrolyte imbalance, diabetes, fits, weak bones and high cholesterol levels. PR-Lupro Injection may cause QT prolongation (heart muscle takes longer than normal to recharge between beats) and may affect heart rhythm, hence heart patients should be cautious while taking PR-Lupro Injection. PR-Lupro Injection can make you feel dizzy and affects your mental ability to drive. Do not drive or operate machinery if you are not mentally alert and focused.

Drug-Drug Interactions

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LeuprorelinCisapride
Critical
LeuprorelinNilotinib
Critical

Drug-Drug Interactions

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LeuprorelinCisapride
Critical
How does the drug interact with PR-Lupro Injection:
Taking leuprolide with cisapride can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although taking PR-Lupro Injection with Cisapride is not recommended, it can be taken if prescribed by a doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or an irregular heartbeat. Do not stop taking any medications without consulting a doctor.
LeuprorelinNilotinib
Critical
How does the drug interact with PR-Lupro Injection:
Using nilotinib together with leuprolide can increase the risk of an irregular heart rhythm that may be serious

How to manage the interaction:
Taking PR-Lupro Injection with Nilotinib is not recommended, as it can result in an interaction. It can be taken if your doctor has suggested it. However, if you experience prolonged diarrhea, vomiting, dizziness, lightheadedness, fainting, or difficulty breathing, contact your doctor immediately. Do not stop using any medications without talking to your doctor.
LeuprorelinDofetilide
Critical
How does the drug interact with PR-Lupro Injection:
Taking leuprolide with dofetilide together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Taking PR-Lupro Injection with Dofetilide together can possibly result in an interaction, they can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
LeuprorelinSaquinavir
Critical
How does the drug interact with PR-Lupro Injection:
Taking leuprolide with Saquinavir together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Taking PR-Lupro Injection with Saquinavir together can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop taking any medications without consulting a doctor.
LeuprorelinVandetanib
Critical
How does the drug interact with PR-Lupro Injection:
Taking PR-Lupro Injection with Vandetanib together can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking PR-Lupro Injection with Vandetanib together can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop taking any medications without consulting a doctor.
LeuprorelinPimozide
Critical
How does the drug interact with PR-Lupro Injection:
Taking PR-Lupro Injection with Pimozide together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Taking PR-Lupro Injection with Pimozide together can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop taking any medications without consulting a doctor.
LeuprorelinEliglustat
Critical
How does the drug interact with PR-Lupro Injection:
Taking Leuprolide and Eliglustat together can raise the risk of an abnormal heart rhythm that may be serious.

How to manage the interaction:
Taking PR-Lupro Injection with Eliglustat together can possibly result in an interaction, they can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
LeuprorelinIbutilide
Critical
How does the drug interact with PR-Lupro Injection:
Using ibutilide together with leuprolide can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking PR-Lupro Injection with Ibutilide together can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop taking any medications without consulting a doctor.
LeuprorelinCitalopram
Critical
How does the drug interact with PR-Lupro Injection:
Coadministration of PR-Lupro Injection and citalopram can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking PR-Lupro Injection and citalopram together can possibly result in an interaction; they can be taken together if advised by your doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or an irregular heartbeat. Do not stop taking any medications without consulting a doctor.
LeuprorelinIvabradine
Severe
How does the drug interact with PR-Lupro Injection:
Using ivabradine together with PR-Lupro Injection can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although taking PR-Lupro Injection and ivabradine together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience prolonged diarrhea, vomiting, dizziness, lightheadedness, fainting, or difficulty breathing, contact your doctor immediately. Do not stop using any medications without talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a fibre-rich diet and include fruits, vegetables and whole grains.
  • Include fish, soy, tomatoes, Brussels sprouts, kale, broccoli and oils containing omega-3 fatty acids such as olive oil as these foods may reduce the risk of prostate cancer.
  • Avoid grilled meat, red meat, saturated fat found in animal products, milk and dairy products.
  • Exercise regularly to lose weight as obesity is also considered a risk factor for prostate cancer.
  • Eat at regular intervals.
  • Opt for a diet rich in whole grains, fruits, vegetables, and low-fat dairy products.

Habit Forming

No

Therapeutic Class

HORMONES

PR-Lupro Injection Substitute

Substitutes safety advice

Product Substitutes

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

PR-Lupro Injection contains Leuprolide acetate, a synthetic hormone that helps reduce the testosterone and oestrogen hormones in men and women, respectively. This process of lowering hormone levels can decrease cancer cell growth in prostate cancer in men and shrinks endometriosis in women.

PR-Lupro Injection affects the hair, making it thin which further causes loss of hair. Hair reduction possibly happens due to the estrogen lowering effect of PR-Lupro Injection. These effects are not long-lasting and may return after some time. If you have any concerns, contact your doctor for further advice.

PR-Lupro Injection may cause impotence and affect fertility in men. It is advised to speak to your doctor if you plan to have a family in the future before starting PR-Lupro Injection.

PR-Lupro Injection should be used with caution in diabetic patients as it may increase the risk of high blood sugar levels. Therefore, regular monitoring of blood sugar levels is recommended while taking PR-Lupro Injection and inform your doctor if you have diabetes before taking PR-Lupro Injection.

PR-Lupro Injection may worsen your mood disorders like depression. Hence it is advised to use PR-Lupro Injection only when you are free from any kind of mental problems. Please consult your doctor for more information.

PR-Lupro Injection may cause osteoporosis (bone thinning) due to the reduction of estrogen in the body. Regular bone density tests may help you monitor osteoporosis. Contact your doctor if you observe any sign of tendon pain or swelling while taking PR-Lupro Injection.

PR-Lupro Injection is not recommended for patients suffering from heart rhythm problems such as arrhythmia (irregular heartbeat) as it may increase the risk of cardiac disease. Therefore, inform your doctor if you have any heart problems before taking PR-Lupro Injection.

Drug-Drug Interactions Checker List

  • QUINIDINE
  • PROCAINAMIDE
  • DISOPYRAMIDE
  • AMIODARONE
  • SOTALOL
  • DEXAMETHASONE
  • METHYLPREDNISOLONE
  • MOXIFLOXACIN
  • METHADONE
  • CITALOPRAM
  • ESCITALOPRAM
  • FLUOXETINE
  • SERTRALINE
  • PAROXETINE

Special Advise

  • Your doctor may advise liver function tests to monitor your liver health since PR-Lupro Injection may cause increased liver enzymes (alanine aminotransferase, serum aspartate and serum transaminases).
  • PR-Lupro Injection may cause increased serum glucose levels (hyperglycaemia), hence inform your doctor if you have diabetes before starting PR-Lupro Injection.
  • Your doctor may advise blood tests, electrolyte levels and regular examinations of the prostate.

  • It is advised to get an electrocardiogram (ECG) done timely to monitor your heart health.

Disease/Condition Glossary

Prostate cancer: It is the cancer of the prostate gland (a small gland under the bladder that secretes fluid that nourishes and protects sperm) found in men. The symptoms include difficulty in urination, pain, numbness or sexual problems. It is the most common type of cancer in men.

Endometriosis: It is a disorder in which tissue lining the uterus grows outside the uterine cavity. It commonly involves ovaries, fallopian tubes and the tissue lining the pelvis. Symptoms of endometriosis include pain and irregular periods.

Precocious Puberty: Precocious puberty occurs when a child's body changes into that of an adult or experiences puberty too soon. If puberty begins before age 8 in girls and before age 9 in boys, it is considered precocious puberty. Symptoms in a girl include first period and breast development, whereas, in a boy, it causes enlarged testicles and penis, deepening voice and facial hair.

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