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  3. Preflunase 0.055% Nasal Spray 12 ml

Written By ,
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Manufacturer/Marketer :

Precept Pharma

Consume Type :

NASAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

GLUCOCORTICOIDS

Country of origin

India
Other Info - PRE1131

FAQs

Preflunase 0.055% Nasal Spray works by blocking certain chemical messengers' production that causes inflammation (redness and swelling) and allergies. As a result, the Preflunase 0.055% Nasal Spray provides relief from the discomfort and irritation in the nose caused due to allergies.

Studies have shown that using inhaled glucocorticoids for the long term in children like Preflunase 0.055% Nasal Spray can reduce linear growth. Prolonged exposure to Preflunase 0.055% Nasal Spray may lead to bone thinning. Preflunase 0.055% Nasal Spray might obstruct calcium absorption and inhibit bone cell growth. Your doctor will monitor your child's growth during the treatment with Preflunase 0.055% Nasal Spray. Inform your doctor if you observe any abnormality in your child's growth.

Preflunase 0.055% Nasal Spray may make your blood glucose levels high. Hence treatment with Preflunase 0.055% Nasal Spray is cautiously administered in patients with diabetes. Please monitor your blood glucose levels regularly and inform your doctor so the dose can be adjusted accordingly.

Use the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule.

Preflunase 0.055% Nasal Spray may cause dry mouth as a temporary side effect in some people. These side effects are not common for all. However, to avoid such side effects, drink plenty of water, regularly rinse your mouth, practice good oral hygiene and suck on sugarless candy. However, if the condition persists or worsens, please consult a doctor.

Disclaimer

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Alcohol

Safe if prescribed

No interaction is found. But as a precautionary measure, limit or avoid alcohol consumption.

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Pregnancy

Caution

Preflunase 0.055% Nasal Spray should only be used during pregnancy if the mother's expected benefits outweigh the possible risks to the unborn child.

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Breast Feeding

Caution

It is not known whether Preflunase 0.055% Nasal Spray is secreted in breast milk. A Preflunase 0.055% Nasal Spray should only be used during breastfeeding if the mother's expected benefit outweighs the child's possible risk.

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Driving

Safe if prescribed

Preflunase 0.055% Nasal Spray does not affect your driving ability.

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Liver

Caution

Preflunase 0.055% Nasal Spray should be used with caution, especially if you have a history of liver diseases/conditions. Your doctor may adjust the dose if required based on your condition.

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Kidney

Safe if prescribed

It is generally safe to be used if you have kidney problems. However, before using Preflunase 0.055% Nasal Spray, consult your doctor.

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Children

Caution

Preflunase 0.055% Nasal Spray is not recommended for children below the age of six years. Proper dose monitoring is required in children above the age of six years by a child specialist.

About Preflunase 0.055% Nasal Spray

Preflunase 0.055% Nasal Spray belongs to a group of medications known as glucocorticoids. Preflunase 0.055% Nasal Spray is primarily used to treat allergic rhinitis symptoms (inflammation of the nose's inner mucous membrane), such as sneezing, runny nose, and sinus discomfort in adults and children above six years. An allergy is an immune system response to foreign elements typically not harmful to your body. These foreign elements are known as ‘allergens.’

Preflunase 0.055% Nasal Spray is a glucocorticoid that helps treat nasal allergy symptoms. It works by blocking certain chemical messengers present in the brain, causing pain, inflammation (swelling), and allergies. As a result, the Preflunase 0.055% Nasal Spray provides relief from the discomfort and irritation in the nose caused due to allergies. Preflunase 0.055% Nasal Spray may lower your ability to fight infections, so stay from people who have any infectious and contagious diseases like measles, tuberculosis, and chickenpox. If you have been around someone who has one of these conditions, please be very cautious, as these diseases are highly contagious, and you might catch these infections Preflunase 0.055% Nasal Spray makes you more prone to infections.

Preflunase 0.055% Nasal Spray should be used in dose and duration as prescribed by your doctor. The most common side effects are nasal ulceration, headache, shortness of breath, soreness, or dryness inside the nose. If these effects appear and are bothersome, call your doctor. Try to stay away from dust as it might worsen your symptoms, and also avoid smoking. Inform your doctor if you have or have ever had nose surgery, injury, or nose sores.

Do not use Preflunase 0.055% Nasal Spray if you are allergic to glucocorticoids or Fluticasone furoate. If you are pregnant or breastfeeding, consult your doctor before using this medicine. Before using Preflunase 0.055% Nasal Spray, please tell your doctor if you have or have ever had glaucoma (an eye disease), cataracts (clouding of the lens of the eye), herpes infection of the eye (sore on the eyelid or eye surface), asthma (sudden episodes of shortness of breath, and trouble breathing). Also, tell your doctor if you have (TB, a type of lung infection), chickenpox, measles, or tuberculosis. Do not use Preflunase 0.055% Nasal Spray in children below six years old.

Uses of Preflunase 0.055% Nasal Spray

Nasal allergic symptoms (allergic rhinitis).

Medicinal Benefits Mweb

Medicinal Benefits

Preflunase 0.055% Nasal Spray is a glucocorticoid that helps to treat inflammation (redness and swelling) and allergies. Preflunase 0.055% Nasal Spray works by blocking certain chemical messenger's production that causes inflammation (redness and swelling) and allergies. As a result, the Preflunase 0.055% Nasal Spray provides relief from the discomfort and irritation in the nose caused due to allergies.

Directions for Use

Nasal spray: Insert the tip of the bottle into a nostril while closing the other nostril and spray towards the sides of the nostril. Keep your head straight and breathe gently. Repeat the same process for another nostril.

Side Effects of Preflunase 0.055% Nasal Spray

  • Nosebleeds
  • Nasal ulceration
  • Headache
  • Shortness of breath

Drug Warnings

Inform your doctor if you have or have ever had nose surgery, injury, or nose sores. Before using Preflunase 0.055% Nasal Spray, please inform your doctor if you have or have ever had glaucoma (an eye disease), cataracts (clouding of the lens of the eye), herpes infection of the eye (an infection that causes a sore on the eyelid or eye surface), asthma (sudden episodes of wheezing, shortness of breath, and trouble breathing). Also, tell your doctor if you have (TB, a type of lung infection), chickenpox, measles, or tuberculosis. If you have been around someone who has one of these conditions, as these diseases are highly contagious, and Preflunase 0.055% Nasal Spray makes you more prone to infections. As a precautionary measure, please stay away from dust to help relieve your symptoms more quickly. Before using Preflunase 0.055% Nasal Spray, inform your doctor if you have ever had diabetes or a weak immune system. After using Preflunase 0.055% Nasal Spray, speak to your doctor immediately if you notice serious side effects such as facial pain, painful swallowing, eye pain, white patches in the nose/back of your throat, or persistent sore throat. Do not use Preflunase 0.055% Nasal Spray at the same time as other nasal sprays containing steroid medication.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Preflunase 0.055% Nasal Spray 12 ml:
Co-administration of Preflunase 0.055% Nasal Spray 12 ml with Mifepristone may make Preflunase 0.055% Nasal Spray 12 ml less effective as a therapy.

How to manage the interaction:
Taking Preflunase 0.055% Nasal Spray 12 ml with Mifepristone is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Preflunase 0.055% Nasal Spray 12 ml:
Co-administration of Preflunase 0.055% Nasal Spray 12 ml with Clarithromycin may significantly increase the absorption of Preflunase 0.055% Nasal Spray 12 ml into the blood stream.

How to manage the interaction:
Co-administration of Clarithromycin and Preflunase 0.055% Nasal Spray 12 ml can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like swelling, weight gain, high blood pressure, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
FluticasoneDinutuximab
Severe
How does the drug interact with Preflunase 0.055% Nasal Spray 12 ml:
Co-administration of Dinutuximab and Preflunase 0.055% Nasal Spray 12 ml may increase the risk of serious and potentially infections.

How to manage the interaction:
Co-administration of Dinutuximab and Preflunase 0.055% Nasal Spray 12 ml can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
FluticasoneCobicistat
Severe
How does the drug interact with Preflunase 0.055% Nasal Spray 12 ml:
When Preflunase 0.055% Nasal Spray 12 ml is taken with Cobicistat, it can cause a decrease in the metabolism of Preflunase 0.055% Nasal Spray 12 ml.

How to manage the interaction:
Co-administration of Cobicistat and Preflunase 0.055% Nasal Spray 12 ml can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like swelling, weight gain, high blood pressure, high blood glucose, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
FluticasoneAmprenavir
Severe
How does the drug interact with Preflunase 0.055% Nasal Spray 12 ml:
Co-administration of Amprenavir and Preflunase 0.055% Nasal Spray 12 ml may significantly increase the absorption of Preflunase 0.055% Nasal Spray 12 ml into the blood stream.

How to manage the interaction:
Co-administration of Amprenavir and Preflunase 0.055% Nasal Spray 12 ml can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like swelling, weight gain, high blood pressure, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
FluticasoneMibefradil
Severe
How does the drug interact with Preflunase 0.055% Nasal Spray 12 ml:
Co-administration of Mibefradil may significantly increase the absorption of Preflunase 0.055% Nasal Spray 12 ml into the bloodstream.

How to manage the interaction:
Taking Preflunase 0.055% Nasal Spray 12 ml with Mibefradil together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - swelling, weight gain, high blood pressure, high blood sugar, weak muscles, feeling down, acne, thinning skin, easy bruising, irregular periods, too much facial or body hair, unusual fat distribution, infection, injury, or a bad asthma attack - make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Preflunase 0.055% Nasal Spray 12 ml:
Co-administration of Ketoconazole and Preflunase 0.055% Nasal Spray 12 ml may significantly increase the absorption of Preflunase 0.055% Nasal Spray 12 ml into the bloodstream.

How to manage the interaction:
If you are supposed to take Preflunase 0.055% Nasal Spray 12 ml and Ketoconazole together, doctor may adjust the dose or monitor you more frequently to use both medications safely. However, if you experience side effects such as weight gain, high blood pressure, swelling, muscle weakness, acne, depression, thinning skin, easy bruising, stretch marks, bone density loss, cataracts, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, contact a doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Preflunase 0.055% Nasal Spray 12 ml:
Coadministration of Itraconazole and Preflunase 0.055% Nasal Spray 12 ml may significantly increase the absorption of Preflunase 0.055% Nasal Spray 12 ml into the bloodstream.

How to manage the interaction:
Preflunase 0.055% Nasal Spray 12 ml and itraconazole may interact, but if a doctor prescribes them, you can still use them. Swelling, high blood pressure, high blood sugar, muscle weakness, depression, acne, stretch marks, easy bruising, bone density loss, cataracts, irregular menstruation, and excessive face or body hair growth are all signs that you need to consult a doctor. Never discontinue taking a medication without consulting a doctor.
How does the drug interact with Preflunase 0.055% Nasal Spray 12 ml:
Taking Ceritinib together with Preflunase 0.055% Nasal Spray 12 ml may increase the blood levels of Preflunase 0.055% Nasal Spray 12 ml.

How to manage the interaction:
If you are supposed to take Preflunase 0.055% Nasal Spray 12 ml and Ceritinib together, your doctor may adjust the dose or monitor you more frequently to use both medications safely. However, if you experience side effects such as high blood pressure, swelling, muscle weakness, acne, depression, thinning skin, easy bruising, stretch marks, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, contact a doctor. Do not discontinue the medication without consulting a doctor.
FluticasoneNefazodone
Severe
How does the drug interact with Preflunase 0.055% Nasal Spray 12 ml:
Co-administration of Nefazodone may significantly increase the absorption of Preflunase 0.055% Nasal Spray 12 ml into the bloodstream.

How to manage the interaction:
Co-administration of Preflunase 0.055% Nasal Spray 12 ml with Nefazodone can possibly result in an interaction, but it can be taken if a doctor has advised it. A doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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FLUTICASONE FUROATE-0.055%W/WOther diseases of liver
Moderate
FLUTICASONE FUROATE-0.055%W/WCushing syndrome
Moderate

Drug-Diseases Interactions

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FLUTICASONE FUROATE-0.055%W/WOther diseases of liver
Moderate
How does the disease interact with Preflunase 0.055% Nasal Spray 12 ml:
Corticosteroids are primarily eliminated by hepatic metabolism, hence liver dysfunction may cause them to accumulate. Hepatic disease patients need to be closely watched.

How to manage the interaction:
Liver disease patients using Preflunase 0.055% Nasal Spray 12 ml should be monitored closely.
FLUTICASONE FUROATE-0.055%W/WCushing syndrome
Moderate
How does the disease interact with Preflunase 0.055% Nasal Spray 12 ml:
Rarely, the use of nasal and inhaled corticosteroids may cause hyperadrenocorticism or worsen its symptoms. Corticosteroid side effects can be lessened by administering them locally rather than systemically, although the dangers are still present. Drugs that are applied topically or inhaled may enter the bloodstream, especially when high concentrations are utilised. It is crucial that the lowest effective dosage be used and that the recommended dosages of the various products not be exceeded. During inhaled or nasal corticosteroid medication, the emergence of symptoms such irregular menstruation, acneiform lesions, cataracts, and cushingoid features may signify overuse.

How to manage the interaction:
The use of inhaled and nasal corticosteroids such as Preflunase 0.055% Nasal Spray 12 ml may rarely precipitate or aggravate conditions of hyperadrenocorticism. Hence, you are advised not to use more than the recommended dosages.
FLUTICASONE FUROATE-0.055%W/WGlaucoma
Moderate
How does the disease interact with Preflunase 0.055% Nasal Spray 12 ml:
In patients with ocular herpes simplex, pharmacologic doses of corticosteroids may raise the risk of corneal perforation. In such patients, corticosteroid therapy should be delivered with caution, both orally and inhalation.

How to manage the interaction:
Inhaled and nasal Preflunase 0.055% Nasal Spray 12 ml should be used with caution in patients with ocular herpes simplex (a type of viral eye infection).
FLUTICASONE FUROATE-0.055%W/WOsteoporosis without pathological fracture
Moderate
How does the disease interact with Preflunase 0.055% Nasal Spray 12 ml:
Long-term inhalation of corticosteroids may cause a decline in bone density. This effect, which has mostly been documented with high dosages (>= 800 mcg/day of beclomethasone or similar for >= 1 year), appears to be dose-related. Patients getting lesser dosages have also been shown to have lower levels of total body calcium. Patients with osteoporosis should be treated with inhaled and nasal corticosteroids over the long term with caution. It is crucial that the lowest effective dosage be used and that the recommended dosages of the various products not be exceeded.

How to manage the interaction:
Long-term therapy with inhaled and nasal corticosteroids should be used with caution in patients with osteoporosis. It is advised not to exceed more than the recommended dosages.

Drug-Drug Interactions Checker List

  • KETOCONAZOLE
  • COBICISTAT
  • NELFINAVIR
  • RITONAVIR

Habit Forming

No

Special Advise

  • Do not stop using Preflunase 0.055% Nasal Spray suddenly without talking to your doctor first, as it may worsen your symptoms.
  • Be careful not to get Preflunase 0.055% Nasal Spray into your eyes or mouth.
  • Preflunase 0.055% Nasal Spray may lower your ability to fight infections, so stay from people who have any infectious and contagious diseases like measles, tuberculosis, chickenpox, etc.
  • Though it is unlikely, this medication may temporarily slow down a child's growth if used for a long time. See the doctor regularly so your child's height can be checked.

Diet & Lifestyle Advise

  • Eat a healthy and balanced diet, and make sure you sleep at least 8 hours a day for a speedy recovery.
  • Please avoid contact with dust as it might worsen your symptoms.
  • Try to include heart-healthy omega-3 fatty acid-containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil.
  • Also, please avoid contact with pollen present in the air, as it might worsen your symptoms.
  • Contact with any person who has chickenpox, measles, tuberculosis should be avoided as it might cause you the same infection as Preflunase 0.055% Nasal Spray makes your body prone to infections.

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