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Written By Divya L , PharmaD
Reviewed By Veda Maddala , M Pharmacy
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

CLINDAMYCIN-600MG

Manufacturer/Marketer :

Preyuda Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTIBIOTICS

Country of origin

India

Manufacturer/Marketer address

88, Om Shiv Nagar Lalghati Bhopal Bhopal Mp 462030 In
Other Info - PRE2002

Author Details

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FAQs

Premycin 600 mg Injection 4 ml is an antibiotic that treats bacterial infections. It works by inhibiting bacterial protein synthesis, which retards bacterial growth.

Premycin 600 mg Injection 4 ml should be used with proper caution and doctor consultation if you have any liver disease, kidney disease, gastrointestinal diseases (colitis, severe stomach cramps, diarrhoea), yellow food dye allergy, and allergic conditions (asthma, hay fever, eczema).

Premycin 600 mg Injection 4 ml can affect the live vaccines like typhoid vaccine and decrease its effectiveness. Please consult a doctor before you start Premycin 600 mg Injection 4 ml if you are undergoing any vaccinations.

Premycin 600 mg Injection 4 ml may cause abnormal liver function tests as one of its side effects. Please ask your doctor before starting Premycin 600 mg Injection 4 ml if you have any history of liver problems.

Diarrhoea can be a side-effect of Premycin 600 mg Injection 4 ml. Clostridium difficile-associated diarrhoea (CDAD) is also reported during usage of antibiotics like Premycin 600 mg Injection 4 ml. Therefore, if you experience diarrhoea, you are advised to undergo an examination to rule out the chances of CDAD following Premycin 600 mg Injection 4 ml therapy.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

Avoid taking alcohol while using Premycin 600 mg Injection 4 ml since it may worsen the side effects.

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Pregnancy

Caution

Please consult your doctor before taking Premycin 600 mg Injection 4 ml if you are pregnant or planning to conceive.

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Breast Feeding

Caution

Premycin 600 mg Injection 4 ml can be excreted into breast milk when used by a nursing mother. Please consult your doctor before taking Premycin 600 mg Injection 4 ml if you are breastfeeding.

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Driving

Caution

There is limited data on how Premycin 600 mg Injection 4 ml affects your driving ability. Please seek medical advice for more information.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before taking Premycin 600 mg Injection 4 ml since it may cause jaundice and abnormal liver function tests.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases before taking Premycin 600 mg Injection 4 ml.

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Children

Caution

Premycin 600 mg Injection 4 ml should be used in children only when prescribed by a doctor. Your doctor will prescribe Premycin 600 mg Injection 4 ml depending on the child's age and body weight.

About Premycin 600 mg Injection 4 ml

Premycin 600 mg Injection 4 ml belongs to the class of 'antibiotics', primarily used to treat serious bacterial infections such as lower respiratory tract infections like pneumonia, empyema, and lung abscess; gynaecological infections like endometritis, nongonococcal tubo-ovarian abscess, pelvic cellulitis, and postsurgical vaginal cuff infection; intra-abdominal infections; septicaemia or sepsis (blood poisoning by bacteria), and bone and joint infections. Bacterial infection occurs when harmful bacteria grow in the body and causes illness. It can infect any part of the body and multiply very quickly. 

Premycin 600 mg Injection 4 ml contains 'Clindamycin' that works by preventing bacterial protein synthesis, leading to the inhibition of bacterial growth. It shows a bacteriostatic effect that stops bacterial reproduction. Premycin 600 mg Injection 4 ml effectively treats infections caused by gram-positive and anaerobic (living without air) bacteria, including susceptible strains of Staphylococcus aureus, Streptococcus pneumoniae, and Clostridium perfringens.

Premycin 600 mg Injection 4 ml will be administered by a healthcare professional. Premycin 600 mg Injection 4 ml may cause side effects, although not everybody gets them. Common side effects of Premycin 600 mg Injection 4 ml include stomach pain, nausea, vomiting, diarrhoea, heartburn, skin rash, pain and swelling at the injection site, and vaginal itching or discharge. Most of these side effects do not require medical attention and gradually resolve over time. If these side effects persist longer, please consult your doctor.

Brief your medical history to the doctor if you are allergic to any of the components in Premycin 600 mg Injection 4 ml. Let your doctor know if you have any liver disease, kidney disease, yellow food dye allergy, colitis (colon inflammation), severe stomach cramps, diarrhoea, and allergic conditions (asthma, hay fever, eczema). Do not use Premycin 600 mg Injection 4 ml while getting vaccinated with live bacterial vaccines (typhoid vaccine) since Premycin 600 mg Injection 4 ml may affect the vaccine's activity. Premycin 600 mg Injection 4 ml should be used only with a doctor's advice during pregnancy and breastfeeding.

Uses of Premycin 600 mg Injection 4 ml

Bacterial infections.

Medicinal Benefits Mweb

Medicinal Benefits

Premycin 600 mg Injection 4 ml is an antibiotic that treats severe/serious bacterial infections. It works by inhibiting bacterial protein synthesis, which inhibits bacterial growth. It shows a bacteriostatic effect, which stops bacterial reproduction but doesn't kill them. Premycin 600 mg Injection 4 ml effectively treats infections caused by gram-positive and anaerobic (living without air) bacteria, including susceptible strains of Staphylococcus aureus, Streptococcus pneumoniae, and Clostridium perfringens. Premycin 600 mg Injection 4 ml is useful in treating lower respiratory tract infections like pneumonia, empyema, and lung abscess; gynaecological infections like endometritis, nongonococcal tubo-ovarian abscess, pelvic cellulitis, and postsurgical vaginal cuff infection; intra-abdominal infections; septicaemia or sepsis (blood poisoning by bacteria), and bone and joint infections.

Directions for Use

Premycin 600 mg Injection 4 ml will be injected by a healthcare professional. Do not self-administer.

Side Effects of Premycin 600 mg Injection 4 ml

  • Pain and swelling at the injection site
  • Stomach pain
  • Nausea
  • Vomiting
  • Diarrhoea
  • Heartburn
  • Skin rash
  • Vaginal itching or discharge 

Drug Warnings

Do not use Premycin 600 mg Injection 4 ml if you are allergic to any of its components. Let your doctor know if you have any liver or kidney diseases, gastrointestinal diseases (colitis, Clostridium difficile-associated diarrhoea), yellow food dye allergy, and allergic conditions (asthma, hay fever, eczema). Do not use Premycin 600 mg Injection 4 ml while getting vaccinated with live bacterial vaccines (typhoid vaccine) since Premycin 600 mg Injection 4 ml may affect the vaccine's activity. Pregnant and breastfeeding women should consult their doctor before taking Premycin 600 mg Injection 4 ml. Avoid alcohol consumption to prevent any undesired effects while using Premycin 600 mg Injection 4 ml.

Drug-Drug Interactions

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ClindamycinAtracurium
Severe
ClindamycinIndinavir
Severe

Drug-Drug Interactions

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ClindamycinAtracurium
Severe
How does the drug interact with Premycin 600 mg Injection 4 ml:
Co-administration of Premycin 600 mg Injection 4 ml with Atracurium can increase the risk of muscle weakness.

How to manage the interaction:
Taking Premycin 600 mg Injection 4 ml with Atracurium together can possibly result in an interaction, but it can be taken if a doctor has advised it. "Premycin 600 mg Injection 4 ml can affect the muscles and nerves in your body. When used with other medications that also affect the muscles and nerves, it can cause a serious problem called neuromuscular blockade. If you have trouble breathing or can't breathe at all, please call your doctor right away." Do not stop using any medications without a doctor's advice.
ClindamycinIndinavir
Severe
How does the drug interact with Premycin 600 mg Injection 4 ml:
Concomitant use of Premycin 600 mg Injection 4 ml with indinavir may increase the effects of Premycin 600 mg Injection 4 ml.

How to manage the interaction:
Although there is a possible interaction, Premycin 600 mg Injection 4 ml can be taken with indinavir if prescribed by the doctor. Consult the prescriber if you experience persistent vomiting, nausea, abdominal pain, or diarrhoea.
ClindamycinEthinylestradiol
Severe
How does the drug interact with Premycin 600 mg Injection 4 ml:
When Ethinylestradiol and Premycin 600 mg Injection 4 ml are taken together, the effects of Premycin 600 mg Injection 4 ml can be reduced.

How to manage the interaction:
There may be a possibility of interaction between Ethinylestradiol and Premycin 600 mg Injection 4 ml, but it can be taken if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ClindamycinCapreomycin
Severe
How does the drug interact with Premycin 600 mg Injection 4 ml:
Co-administration of Capreomycin with Premycin 600 mg Injection 4 ml can increase the risk of kidney or nerve damage.

How to manage the interaction:
There may be a possibility of interaction between Premycin 600 mg Injection 4 ml and Capreomycin, but it can be taken if prescribed by a doctor. Do not discontinue any medications without first consulting your doctor.
ClindamycinBalsalazide
Severe
How does the drug interact with Premycin 600 mg Injection 4 ml:
Co-administration of Premycin 600 mg Injection 4 ml with Balsalazide may reduce the effectiveness of Balsalazide.

How to manage the interaction:
Although there is a possible interaction, Premycin 600 mg Injection 4 ml can be taken with balsalazide if prescribed by the doctor. Consult the prescriber if you have any concerns, the doctor may prescribe alternatives that do not interact, dose adjustment, or more frequent monitoring to safely use both medications. Do not discontinue the medication without consulting a doctor.
ClindamycinClarithromycin
Severe
How does the drug interact with Premycin 600 mg Injection 4 ml:
Taking Premycin 600 mg Injection 4 ml with clarithromycin may increase the effects of Premycin 600 mg Injection 4 ml.

How to manage the interaction:
Although there is a possible interaction, Premycin 600 mg Injection 4 ml can be taken with clarithromycin if prescribed by the doctor. Consult the prescriber if you experience persistent vomiting, nausea, abdominal pain, or diarrhea. Do not discontinue the medication without consulting a doctor.
ClindamycinItraconazole
Severe
How does the drug interact with Premycin 600 mg Injection 4 ml:
Concomitant use of Premycin 600 mg Injection 4 ml with itraconazole can reduce the metabolism and increase the levels of Premycin 600 mg Injection 4 ml in the body. This may increase the risk or severity of side effects.

How to manage the interaction:
Although there is a possible interaction, Premycin 600 mg Injection 4 ml can be taken with itraconazole if prescribed by the doctor. Consult a doctor immediately if you experience persistent vomiting, nausea, abdominal pain, or diarrhea. Do not stop using any medications without first talking to your doctor.
ClindamycinCeritinib
Severe
How does the drug interact with Premycin 600 mg Injection 4 ml:
Concomitant use of Premycin 600 mg Injection 4 ml with ceritinib can increase the effects of Premycin 600 mg Injection 4 ml

How to manage the interaction:
Although there is a possible interaction, Premycin 600 mg Injection 4 ml can be taken with ceritinib if prescribed by the doctor. Consult the prescriber if you experience persistent vomiting, nausea, abdominal pain, or diarrhoea.
ClindamycinEstradiol
Severe
How does the drug interact with Premycin 600 mg Injection 4 ml:
When taken in combination, Premycin 600 mg Injection 4 ml can lower the amount or action of estradiol.

How to manage the interaction:
Co-administration of Estradiol with Premycin 600 mg Injection 4 ml can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.
ClindamycinAmprenavir
Severe
How does the drug interact with Premycin 600 mg Injection 4 ml:
Co-administration of Amprenavir together with Premycin 600 mg Injection 4 ml can increase the effects of Premycin 600 mg Injection 4 ml.

How to manage the interaction:
Co-administration of Premycin 600 mg Injection 4 ml with Amprenavir can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have ongoing feelings of sickness, throwing up, having loose stools, or pain in your stomach, it's important to contact your doctor right away. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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CLINDAMYCIN-600MGOther bacterial intestinal infections
Severe
CLINDAMYCIN-600MGDisorders related to short gestation and low birth weight, not elsewhere classified
Severe

Drug-Diseases Interactions

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CLINDAMYCIN-600MGOther bacterial intestinal infections
Severe
How does the disease interact with Premycin 600 mg Injection 4 ml:
Almost all antibacterial medications have been associated with reports of Clostridioides difficile-associated diarrhoea (CDAD), formerly known as pseudomembranous colitis. It can vary from mild diarrhoea to deadly colitis.

How to manage the interaction:
Clostridioides difficile-associated diarrhea (CDAD) ranging from mild diarrhoea to colitis has been reported during treatment with antibacterial agents. Therapy should be administered cautiously in patients with history of gastrointestinal disease, particularly colitis and pseudomembranous colitis. Appropriate fluid and electrolyte management, protein supplementation, and antibacterial treatment of C difficile is advised.
CLINDAMYCIN-600MGDisorders related to short gestation and low birth weight, not elsewhere classified
Severe
How does the disease interact with Premycin 600 mg Injection 4 ml:
Benzyl alcohol is frequently used as a preservative in the formulation of multidose vials for parenteral medicines. Manufacturers of pharmaceuticals believe that using them in neonates, especially preterm and underweight newborns, is contraindicated. In low birth weight preterm newborns, the use of benzyl alcohol in bacteriostatic saline intravascular flush and endotracheal tube lavage solutions has been linked to mortality and serious respiratory and metabolic problems.

How to manage the interaction:
Parenteral medications containing benzyl alcohol as a preservative are contraindicated in neonates, particularly premature infants and infants of low birth weight.
CLINDAMYCIN-600MGOther diseases of liver
Moderate
How does the disease interact with Premycin 600 mg Injection 4 ml:
The liver is the primary site of Premycin 600 mg Injection 4 ml metabolism. Patients with significantly impaired hepatic function may have a rise in the blood concentration of Premycin 600 mg Injection 4 ml and a prolongation of the half-life. Additionally, the drug's usage may result in abnormal liver enzyme levels and jaundice. Patients with liver problems should receive Premycin 600 mg Injection 4 ml therapy with caution. When given every 8 hours, dosage modifications might not be required. However, with high-dose therapy, serum concentrations should be observed, and during prolonged therapy, regular liver function tests should be carried out.

How to manage the interaction:
Premycin 600 mg Injection 4 ml is primarily metabolized by the liver. Therapy with Premycin 600 mg Injection 4 ml should be administered cautiously in patients with liver disease. Serum concentrations should be monitored during high-dose therapy, and periodic liver function tests should be performed during prolonged therapy.
CLINDAMYCIN-600MGOther disorders of kidney and ureter, not elsewhere classified
Moderate
How does the disease interact with Premycin 600 mg Injection 4 ml:
Premycin 600 mg Injection 4 ml is partially removed by the kidney. Premycin 600 mg Injection 4 ml should be used with caution in individuals with significantly impaired renal function. Dosage changes are probably to be required. Serum Premycin 600 mg Injection 4 ml concentrations should be monitored throughout high-dose therapy, and renal function tests should be conducted on a regular basis during extended medication.

How to manage the interaction:
Therapy with Premycin 600 mg Injection 4 ml should be administered cautiously in patients with severely impaired renal function. Serum Premycin 600 mg Injection 4 ml concentrations should be monitored during high-dose therapy, and periodic renal function tests should be performed during prolonged therapy.
CLINDAMYCIN-600MGOther disorders of kidney and ureter, not elsewhere classified
Moderate
How does the disease interact with Premycin 600 mg Injection 4 ml:
Premycin 600 mg Injection 4 ml is partially removed by the kidney. Premycin 600 mg Injection 4 ml should be used with caution in individuals with significantly impaired renal function. Dosage changes are probably to be required. Serum Premycin 600 mg Injection 4 ml concentrations should be monitored throughout high-dose therapy, and renal function tests should be conducted on a regular basis during extended medication.

How to manage the interaction:
Therapy with Premycin 600 mg Injection 4 ml should be administered cautiously in patients with severely impaired renal function. Serum Premycin 600 mg Injection 4 ml concentrations should be monitored during high-dose therapy, and periodic renal function tests should be performed during prolonged therapy.

Drug-Drug Interactions Checker List

  • ERYTHROMYCIN
  • RIFAMPIN
  • ATRACURIUM
  • VECURONIUM

Habit Forming

No

Special Advise

  • Liver and kidney function monitoring (Liver and kidney function tests) are recommended in patients with severe liver and kidney diseases.
  • Clostridium difficile-associated diarrhoea (CDAD) is reported during the usage of antibiotics. Please consult your doctor if you experience prolonged diarrhoea.

Diet & Lifestyle Advise

  • Wash your hands often to maintain cleanliness.
  • Avoid sharing personal items like shaving razors.
  • Include whole-grain foods like multigrain bread and brown rice in your diet. 
  • Taking probiotics after an antibiotic treatment reduces the risk of antibiotic-associated diarrhoea. 
  • Try taking yoghurt, cheese, sauerkraut, and kimchi that help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet that is easily digested by your gut bacteria. Fibre foods may also help restore healthy gut bacteria after a course of antibiotics. 
  • Avoid intake of alcoholic beverages as it may cause dehydration and affect your sleep. 
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep. 

Premycin 600 mg Injection 4 ml Substitute

Substitutes safety advice
  • Clindatec 600 mg Injection 4 ml

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    57.15per tablet
  • Dalcinex 600 mg Injection 4 ml

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    57.27per tablet
  • Humclid 600mg Injection

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    50.85per tablet
  • KLINZ 600MG INJECTION 4ML

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    50.63per tablet
  • Korey Cin 600mg Injection

    by Others

    51.75per tablet

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