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  1. Home
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  3. Primecobal 500Mcg/1Ml Inj

Primecobal 500Mcg/1Ml Inj, Pack of 1 Injection
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
48 Hrs returnable
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COD available

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Whats That

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Composition :

MECOBALAMIN-500MCG

Manufacturer/Marketer :

Starus Pharmaceuticals

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

VITAMINS

Country of origin

India

Manufacturer/Marketer address

STARUS PHARMACEUTICALS PRIVATE LIMITED, 1st FLOOR, MOPARTHY TOWERS, LANE BESIDE KARACHI BAKERY, ROAD NO:1, BANJARA HILLS, HYDERABAD-500034, INDIA
Other Info - PRI0459

Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 8, 2025 | 9:45 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Mecobalamin is a synthetic form of vitamin B12. It works by increasing vitamin B12 levels in your body, assisting in the treatment of anaemias and nerve problems.

Pain, swelling, or itchy skin where your injection was administered; these symptoms are often minimal and should last only a few hours. If the discomfort is affecting you, you might seek a healthcare expert for a mild pain reliever.

When your vitamin B12 (Mecobalamin) blood levels return to normal, you may be able to discontinue taking Mecobalamin. However, if your diet lacks vitamin B12 or you cannot absorb enough vitamin B12 from food, you may need to take it for the rest of your life.

Vitamin B12 deficiency occurs when you don't have enough Methylcobalamin or Mecobalamin levels in the body. You can include natural Vitamin B12 sources like eggs, beef, liver, chicken, trout, salmon, tuna, fish, clams, fortified breakfast cereal, low-fat milk, yoghurt, and cheese in your diet to treat the deficiency. If you still have low levels of B12, please consult your doctor.

Diarrhoea might be a side-effect of Primecobal 500Mcg/1Ml Inj. Drink lots of fluids and eat food rich in fibre. If you find blood in your stools (tarry stools) or if you experience excess diarrhoea, consult your doctor.

If you miss a dose, take it as soon as you remember. However, if it is time for the next scheduled dose, skip the missed dose and follow your usual dosage.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

Alcohol does not affect the results of Primecobal 500Mcg/1Ml Inj. However, excessive alcohol consumption regularly can result in folate-deficient anaemia.

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Pregnancy

Caution

Primecobal 500Mcg/1Ml Inj may be unsafe to take during pregnancy. If you are pregnant, inform your doctor before taking this medicine. Your doctor may prescribe Primecobal 500Mcg/1Ml Inj if the benefits outweigh the risks.

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Breast Feeding

Caution

Primecobal 500Mcg/1Ml Inj is considered safe to be used in breastfeeding. However, if you are breastfeeding, inform your doctor before taking Primecobal 500Mcg/1Ml Inj.

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Driving

Safe if prescribed

Primecobal 500Mcg/1Ml Inj does not impact an ability to drive or operate capabilities.

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Liver

Caution

Primecobal 500Mcg/1Ml Inj should administer with caution in patients with severe liver disease. If you have liver problems, inform your doctor before taking Primecobal 500Mcg/1Ml Inj. Your doctor may adjust the dose of this medicine based on your condition.

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Kidney

Caution

Primecobal 500Mcg/1Ml Inj should administer with caution in patients with kidney disease. If you have kidney problems, inform your doctor before taking Primecobal 500Mcg/1Ml Inj. Your doctor may adjust the dose of this medicine based on your condition.

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Children

Caution

Primecobal 500Mcg/1Ml Inj can be prescribed for children below 12 years, but your doctor made dose adjustments.

Product Substitutes

Reference

  1. https://www.everydayhealth.com/drugs/methylcobalamin-vitamin-b12-oral-injection
  2. https://www.mims.com/india/drug/info/mecobalamin?type=full&mtype=generichttp://peripheralneuropathycenter.uchicago.edu/learnaboutpn/typesofpn/systemic/nutrition.shtml
  3. https://www.healthline.com/health/megaloblastic-anemia
  4. https://www.drugs.com/mtm/methylcobalamin-vitamin-b12.html#interactions
  5. https://www.nhs.uk/medicines/cyanocobalamin

About Primecobal 500Mcg/1Ml Inj

Primecobal 500Mcg/1Ml Inj belongs to the Vitamins class, primarily used to treat peripheral neuropathies and megaloblastic anaemia caused by vitamin B12 deficiency. Vitamin B12 is a vital dietary nutrient, and deficiency of vitamin B12 can lead to peripheral neuropathy, megaloblastic anaemia, and many other serious conditions.

Primecobal 500Mcg/1Ml Inj contains Mecobalamin, a form of vitamin B12 that helps protect the nerves from damage and also helps to promote blood cell production. It regulates body functions, such as cell multiplication, blood formation, and protein synthesis.

Primecobal 500Mcg/1Ml Inj is a prescription-only medication. It will be administered by a healthcare professional; do not self-administer. You may experience pain, itching, swelling or redness around the injection site, nausea, vomiting, diarrhoea, and headache. Most of these side effects do not require medical attention and resolve gradually over time. However, you are advised to talk to your doctor if you have signs of an allergic reaction, such as swelling of the face, lips, or tongue or breathing problems.

To treat your condition effectually, continue taking Primecobal 500Mcg/1Ml Inj for as long as your doctor has prescribed. Please do not stop taking Primecobal 500Mcg/1Ml Inj without consulting your doctor. Do not take Primecobal 500Mcg/1Ml Inj if you are pregnant or breastfeeding unless prescribed by the doctor. Primecobal 500Mcg/1Ml Inj should be given to children as advised by your doctor. Keep your doctor informed about your present and past medical history and ongoing medicines to rule out any side effects.

Uses of Primecobal 500Mcg/1Ml Inj

Peripheral neuropathy, megaloblastic anaemia.

Medicinal Benefits Mweb

Medicinal Benefits

Mecobalamin (Methylcobalamin) is a coenzyme form of vitamin B12. It regulates body functions, such as cell multiplication, blood formation, and protein synthesis. It is also used in the treatment of alcoholic neuropathy, pernicious anaemia (red blood cells are not produced due to Vitamin B12 deficiency), diabetic neuropathy (nerve damage due to high blood sugar levels), and multiple sclerosis (immune system disease affecting the brain).

Directions for Use

Primecobal 500Mcg/1Ml Inj will be administered by a qualified healthcare professional. Hence, do not self-administer.

Side Effects of Primecobal 500Mcg/1Ml Inj

  • Painfulness or tenderness at the injection site
  • Nausea
  • Vomiting
  • Diarrhoea
  • Loss of appetite
  • Headache

Drug Warnings

Do not consume Primecobal 500Mcg/1Ml Inj if you are allergic to any ingredients in Primecobal 500Mcg/1Ml Inj. To treat your condition effectually, continue taking Primecobal 500Mcg/1Ml Inj for as long as your doctor has prescribed. Please do not stop taking Primecobal 500Mcg/1Ml Inj without consulting your doctor. Do not take Primecobal 500Mcg/1Ml Inj if you are pregnant or breastfeeding unless prescribed by the doctor. Primecobal 500Mcg/1Ml Inj should be given to children as advised by your doctor. Inform your doctor if you have low potassium levels in the blood, iron or folic acid deficiency, or if you have had optic nerve damage. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Drug-Drug Interactions

verifiedApollotooltip
MecobalaminChloramphenicol
Moderate
MecobalaminNeomycin
Moderate

Drug-Drug Interactions

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MecobalaminChloramphenicol
Moderate
How does the drug interact with Primecobal 500Mcg/1Ml Inj:
Coadministration of Primecobal 500Mcg/1Ml Inj with Chloramphenicol can impair absorption and increase the levels of Primecobal 500Mcg/1Ml Inj which can increase the risk or severity of side effects.

How to manage the interaction:
Taking Primecobal 500Mcg/1Ml Inj with Chloramphenicol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of Vomiting, Diarrhoea, Nausea, Headache, or Loss of appetite, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
MecobalaminNeomycin
Moderate
How does the drug interact with Primecobal 500Mcg/1Ml Inj:
Coadministration of Primecobal 500Mcg/1Ml Inj with Neomycin can impair the absorption of Primecobal 500Mcg/1Ml Inj and increase its levels which can increase the risk or severity of side effects.

How to manage the interaction:
Taking Primecobal 500Mcg/1Ml Inj with Neomycin together is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of Vomiting, Diarrhoea, Nausea, Headache, or Loss of appetite you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • AMINOSALICYLIC ACID
  • ARSENIC TRIOXIDE
  • CHLORAMPHENICOL

Habit Forming

No

Diet & Lifestyle Advise

  • Take fresh fruits and vegetables into your diet.
  • Eat fortified cereals in your diet.
  • Drink milk and make cheese and yoghurt in your diet.
  • Take eggs, meat, and fish into your diet.
  • Avoid oily and canned foods.
  • Avoid tea and coffee.
  • Quit smoking and avoid drinking alcohol.

Primecobal 500Mcg/1Ml Inj Substitute

Substitutes safety advice

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