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Written By ,
Reviewed By Sunny S , MBBS
48 Hrs returnable
COD available

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Whats That

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Composition :

ESTRADIOL-2MG

Manufacturer/Marketer :

Zydus Cadila

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

HORMONES

Country of origin

INDIA

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India
Other Info - PRI0403

FAQs

Primiwal-E2 Tablet works by replacing the normal hormone estrogen functions in the body and treats symptoms associated with menopause.

Do not use Primiwal-E2 Tablet if you are allergic to peanuts, have unusual vaginal bleeding, have/had any cancer (breast or uterus cancer), or undergoing any other estrogen treatment. Tell your doctor if you had a heart attack, stroke, blood clot, or liver problems, if you are pregnant, breastfeeding, or planning to get pregnant.

No, Primiwal-E2 Tablet should not be taken if you are undergoing surgery. You should inform your doctor, and he might ask you to stop hormone replacement therapy about 4 to 6 weeks before surgery to reduce the risk of blood clots.

Primiwal-E2 Tablet may cause either weight gain or weight loss. It is a common side effect of Primiwal-E2 Tablet . Regular exercise and eating a healthy diet can help prevent weight gain.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

You are recommended not to consume alcohol along with Primiwal-E2 Tablet to avoid unpleasant side effects.

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Pregnancy

Unsafe

Primiwal-E2 Tablet is not recommended during pregnancy as it may harm the baby and cause serious complications for the baby and mother.

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Breast Feeding

Unsafe

Primiwal-E2 Tablet is not recommended for breastfeeding mothers as it is known to cause harm to the baby.

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Driving

Safe if prescribed

It is not known to cause any side effects which may affect driving.

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Liver

Caution

Primiwal-E2 Tablet should be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Primiwal-E2 Tablet should be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Caution

Primiwal-E2 Tablet is not recommended for children below 12 years of age.

About Primiwal-E2 Tablet

Primiwal-E2 Tablet contains a semi-synthetic female hormone Estradiol, indicated for hormonal replacement therapy for treating hypoestrogenism (estrogen deficiency), osteoporosis (thinning of bones) and symptoms associated with menopause (itching, dryness in the vagina, hot flashes). In addition to this, it also helps in preventing osteoporosis. Primiwal-E2 Tablet is prescribed when the body is not producing a sufficient amount of natural estrogen.

Primiwal-E2 Tablet contains estradiol which regulates the menstrual cycle and ovulation. Primiwal-E2 Tablet works by replacing the normal hormone estrogen functions in the body and treats symptoms associated with menopause. 

You are advised to take Primiwal-E2 Tablet for as long as your doctor has prescribed it for you, depending upon your medical condition. You may experience headache, bloating, hair loss, nausea, breast pain, weight gain, and irregular vaginal bleeding in some cases. Most of these side effects of Primiwal-E2 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Inform your doctor if you have any history of vaginal bleeding, breast cancer, or blood clot in the legs or lungs. If you are pregnant or breastfeeding, please do not take Primiwal-E2 Tablet . While taking Primiwal-E2 Tablet , your doctor may advise regular tests to monitor its working. Grapefruit juice and St.John’s wort (a natural remedy for depression) should not be taken along with Primiwal-E2 Tablet . 

Uses of Primiwal-E2 Tablet

Hormonal replacement therapy, Hypoestrogenism (estrogen deficiency), Osteoporosis (thinning of bones), Symptoms associated with menopause (itching, dryness in vagina, hot flushes)

Medicinal Benefits Mweb

Medicinal Benefits

Primiwal-E2 Tablet contains a synthetic female hormone that regulates ovulation and menstruation in women. Primiwal-E2 Tablet is given as a hormone replacement therapy for estrogen. It is also used in the treatment to relieve symptoms of menopause, such as mood swings, reduced sex drive, hot flashes, night sweats and vaginal dryness. 

Directions for Use

Swallow Primiwal-E2 Tablet as a whole with a glass of water, do not chew or crush it.

Side Effects of Primiwal-E2 Tablet

  • Headache
  • Bloating
  • Hair loss
  • Nausea
  • Weight gain
  • Breast pain
  • Irregular vaginal bleeding

Drug Warnings

Do not take Primiwal-E2 Tablet if you are allergic to any of its ingredients. Inform your doctor if you have breast cancer, vaginal bleeding, blood clot in the leg (deep venous thrombosis), lungs (pulmonary embolism), vein (thrombosis), cancer of the endometrium (womb lining), any blood clotting disorder, recently had a heart attack, liver or kidney disease, porphyria (a group of liver disease), high blood pressure, if you are pregnant or breastfeeding. Avoid smoking as it greatly increases the risk of blood clots, stroke, and heart attack while taking Primiwal-E2 Tablet . Grapefruit juice and St. John’s wort (a natural remedy for depression) should not be taken along with Primiwal-E2 Tablet . 

Drug-Drug Interactions

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EstradiolBivalirudin
Critical
EstradiolClindamycin
Severe

Drug-Drug Interactions

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EstradiolBivalirudin
Critical
How does the drug interact with Primiwal-E2 Tablet:
When Etodolac is taken with Bivalirudin, the risk or severity of bleeding and haemorrhage increases.

How to manage the interaction:
Taking Bivalirudin with Primiwal-E2 Tablet can cause an interaction, consult a doctor before taking it. Do not discontinue any medications without a doctor's advice.
EstradiolClindamycin
Severe
How does the drug interact with Primiwal-E2 Tablet:
When taken in combination, clindamycin can lower the amount or action of Primiwal-E2 Tablet.

How to manage the interaction:
Co-administration of Primiwal-E2 Tablet with Clindamycin can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.
EstradiolCarfilzomib
Severe
How does the drug interact with Primiwal-E2 Tablet:
Carfilzomib can cause serious blood clots and taking it alongside Primiwal-E2 Tablet may enhance the risk.

How to manage the interaction:
Co-administration of Primiwal-E2 Tablet with Carfilzomib can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience symptoms like chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness, or swelling in an arm or leg, or numbness or weakness on one side of the body, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
EstradiolLenalidomide
Severe
How does the drug interact with Primiwal-E2 Tablet:
Coadministration of Primiwal-E2 Tablet and Lenalidomide can increase the risk of blood clots.

How to manage the interaction:
Although there is an interaction between lenalidomide and Primiwal-E2 Tablet, it can be taken if your doctor has advised it. However, if you experience chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
EstradiolPomalidomide
Severe
How does the drug interact with Primiwal-E2 Tablet:
Co-administration of Primiwal-E2 Tablet and Pomalidomide can increase the risk of serious blood clots.

How to manage the interaction:
There may be a possibility of interaction between Primiwal-E2 Tablet and Pomalidomide, but it can be taken if prescribed by a doctor. However, if you experience symptoms like chest pain, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness, or swelling in an arm or leg, or numbness or weakness on one side of the body, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EstradiolThalidomide
Severe
How does the drug interact with Primiwal-E2 Tablet:
Taking thalidomide together with Primiwal-E2 Tablet may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking Primiwal-E2 Tablet and thalidomide together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
EstradiolLetrozole
Severe
How does the drug interact with Primiwal-E2 Tablet:
Letrozole may have a negative effect when used with Primiwal-E2 Tablet, making it less effective in treating your disease.

How to manage the interaction:
Although taking Letrozole and Primiwal-E2 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
EstradiolAnastrozole
Severe
How does the drug interact with Primiwal-E2 Tablet:
Primiwal-E2 Tablet may interfere with anastrozole's function and make it less effective in treating your condition.

How to manage the interaction:
Co-administration of Anastrozole with Primiwal-E2 Tablet can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.
EstradiolDantrolene
Severe
How does the drug interact with Primiwal-E2 Tablet:
The usage of Primiwal-E2 Tablet with dantrolene might have significant adverse effects on your liver.

How to manage the interaction:
Taking Primiwal-E2 Tablet with Dantrolene together can result in an interaction, but it can be taken if a doctor has advised it. However, if you have a fever, chills, joint pain or swelling, severe fatigue or weakness, unusual bleeding or bruising, skin rash or itching, lack of appetite, nausea, vomiting, or yellowing of the skin or whites of your eyes, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
EstradiolExemestane
Severe
How does the drug interact with Primiwal-E2 Tablet:
Using Primiwal-E2 Tablet with Exemestane may interfere with Exemestane's activity and make it less effective in treating the condition.

How to manage the interaction:
Although there is a possible interaction between Exemestane and Primiwal-E2 Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • CARBAMAZEPINE
  • PHENYTOIN
  • GRISEOFULVIN
  • RIFAMPICIN
  • RITONAVIR
  • NELFINAVIR
  • EFAVIRENZ
  • BOSENTAN
  • ASPIRIN

Habit Forming

No

Diet & Lifestyle Advise

  • Do regular exercise and physical activity to minimize hot flashes and improve sleep. Besides this, weight-bearing exercises can help in making your bone strong. Aerobics, yoga, and activities like tai chi may help relax the body and mind.
  • Try to wear loose clothes before going to bed and sleep in a cool, well-ventilated room. Doing this can prevent symptoms of hot flashes and night sweats. Take minimum sleep of 8 hours. 
  • Avoid or limit intake of caffeine-containing beverages, alcohol, and spicy food, as these are known triggering agents for hot flushes.
  • Try to be stress-free to improve your mood swings due to hormonal fluctuations. 
  • Quitting smoking will help reduce hot flashes and your risk of developing chronic conditions like heart disease, stroke, and cancer.

Primiwal-E2 Tablet Substitute

Substitutes safety advice
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