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Therapeutic Class

MULTIMINERALS

Drug-Drug Interactions Checker List

  • ESTRAMUSTINE
  • CHOLESTYRAMINE
  • DIGITALIS
  • CIPROFLOXACIN
  • LEVOFLOXACIN
  • GATIFLOXACIN
  • SPARFLOXACIN
  • OFLOXACIN
  • KETOCONAZOLE

Drug-Drug Interactions

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CalcitriolCalcifediol
Severe
CalcitriolColecalciferol
Severe

Drug-Drug Interactions

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CalcitriolCalcifediol
Severe
How does the drug interact with Problast Capsule:
Co-administration of Calcifediol and Problast Capsule are forms of vitamin D, and taking too much vitamin D may lead to toxic effects related to increased calcium levels in the blood and urine.

How to manage the interaction:
Taking Calcifediol with Problast Capsule can lead to an interaction, it can be taken if advised by a doctor. Consult the prescriber if you experience symptoms of vitamin D intoxication such as weakness, headache, fatigue, drowsiness, vertigo, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, metallic taste, muscle pain, bone pain, muscle incoordination, and low muscle tone. Do not discontinue the medication without consulting a doctor.
CalcitriolColecalciferol
Severe
How does the drug interact with Problast Capsule:
Co-administration of Cholecalciferol and Problast Capsule are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.

How to manage the interaction:
Although there is a possible interaction between colecalciferol and Problast Capsule, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
CalcitriolRifapentine
Severe
How does the drug interact with Problast Capsule:
Co-administration of Rifapentine with Problast Capsule may decrease the effects of Problast Capsule.

How to manage the interaction:
Although there is an interaction, Problast Capsule can be taken with Rifapentine if prescribed by the doctor. The doctor may recommend dose adjustment or special tests to use both medicines safely. Do not discontinue the medication without consulting a doctor.
CalcitriolDigitoxin
Severe
How does the drug interact with Problast Capsule:
Co-administration of Problast Capsule with Digitoxin may increase the risk or severity of digitoxin toxicity and irregular heart rhythm.

How to manage the interaction:
Although there is an interaction, Problast Capsule can be taken with Digitoxin if prescribed by the doctor. Consult the prescriber if you experience symptoms that could indicate high blood calcium, such as weakness, fatigue, headache, dizziness, drowsiness, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, a metallic taste in the mouth, bone or muscle pain, incoordination, frequent urination, and weight loss. Also, seek medical attention if you experience symptoms of digitoxin toxicity, such as blurred vision, slow pulse, or irregular heartbeats. Do not discontinue the medication without consulting a doctor.
CalcitriolDihydrotachysterol
Severe
How does the drug interact with Problast Capsule:
Co-administration of Problast Capsule with Dihydrotachysterol can increase the risk of adverse effects.

How to manage the interaction:
Co-administration of Dihydrotachysterol with Problast Capsule can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, throwing up, constipation, dry mouth, strange taste in your mouth, muscle or bone pain, trouble coordinating movements, weak muscles, peeing a lot, feeling very thirsty, losing weight, eye infection, sensitivity to light, itching, or a higher body temperature - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
CalcitriolIsoniazid
Severe
How does the drug interact with Problast Capsule:
Co-administration of Isoniazid with Problast Capsule may decrease the effects of Problast Capsule.

How to manage the interaction:
Although there is an interaction, Problast Capsule can be taken with isoniazid if prescribed by the doctor. Do not stop using any medications without talking to a doctor. Do not discontinue the medication without consulting a doctor.
CalcitriolCarbamazepine
Severe
How does the drug interact with Problast Capsule:
Co-administration of Problast Capsule with Carbamazepine may decrease the effects of Problast Capsule.

How to manage the interaction:
Although there is an interaction, Problast Capsule can be taken with Carbamazepine if prescribed by the doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
CalcitriolAmobarbital
Severe
How does the drug interact with Problast Capsule:
Co-administration of Amobarbital and Problast Capsule may decrease the effects of Problast Capsule.

How to manage the interaction:
Co-administration of Problast Capsule with Amobarbital can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms, it's important to contact a doctor right away. Do not stop using any medications without talking to a doctor.
CalcitriolBurosumab
Severe
How does the drug interact with Problast Capsule:
Co-administration of Problast Capsule and Burosumab may cause increases in phosphorus and vitamin D levels in the blood, which may lead to an increased risk of kidney stones.

How to manage the interaction:
There may be a possibility of interaction between Problast Capsule and Burosumab, but it can be taken if prescribed by a doctor. If you have any of these symptoms like kidney stones, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice. Do not discontinue the medication without consulting a doctor.
CalcitriolOrlistat
Severe
How does the drug interact with Problast Capsule:
Co-administration of Orlistat with Problast Capsule may reduce the levels of Problast Capsule which can lead to low treatment outcomes.

How to manage the interaction:
Although there is an interaction, Problast Capsule can be taken with Orlistat when prescribed by the doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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CALCITRIOL-0.25MCG+CALCIUM CARBONATE-500MG+ZINC-7.5MGFiber rich foods, Potassium rich foods
Moderate

Drug-Food Interactions

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CALCITRIOL-0.25MCG+CALCIUM CARBONATE-500MG+ZINC-7.5MGFiber rich foods, Potassium rich foods
Moderate
Common Foods to Avoid:
Spinach

How to manage the interaction:
foods high in oxalic acid (spinach) may decrease calcium absorption. Consider taking calcium at least 2 hours before or after eating meals high in oxalic acid or phytic acid.

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug Warnings

If you are known to be allergic to Problast Capsule or any other medicines, please tell your doctor. If you are pregnant or planning to become pregnant, it is advised to inform your doctor before using Problast Capsule . Higher doses of Vitamin D than the recommended daily dose should be used in pregnant women only when advised by the doctor. Calcitriol in higher doses may harm the fetus. Problast Capsule may pass into the breast milk; hence consult your doctor before taking Problast Capsule if you are a breastfeeding mother. Problast Capsule should be used with caution in children and only if recommended by a doctor. Calcitriol in Problast Capsule can affect growth in children. Inform your doctor if your child is not growing at a normal rate while using Problast Capsule . Problast Capsule is not recommended if you have hypercalcemia (high calcium levels), metastatic calcification (extra deposits of calcium in the body), hypervitaminosis D (high vitamin D levels), and malabsorption syndrome (difficulty absorbing nutrition from food). Inform your doctor before taking Problast Capsule if you have any heart/kidney/liver/blood vessel diseases, kidney stones, sarcoidosis (growth of inflammatory cells in different parts of the body), Crohn's disease (inflammatory bowel disease), Whipple's disease (bacterial infection affecting joints and digestive system), achlorhydria (little or no stomach acid), low levels of bile, and phosphate imbalance. Problast Capsule contains sugar or sorbitol; hence caution should be taken to have an intolerance to sugars, diabetes, and phenylketonuria (increased levels of an amino acid called phenylalanine).

Side Effects of Problast Capsule

  • Nausea
  • Vomiting
  • Headache
  • Stomach pain
  • Constipation
  • Mood changes
  • Tiredness/ weakness
  • Fast or pounding heartbeat

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water. Do not crush, chew, or break it. Liquid: Shake the bottle well before use. Take the recommended dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Medicinal Benefits Mweb

Medicinal Benefits

Problast Capsule is a combination of three drugs, namely; Calcium carbonate (mineral), Calcitriol (Vitamin D3) and Zinc (mineral) used to treat low blood calcium levels and various associated conditions caused by low calcium levels in the body, such as osteoporosis (weak and brittle bones), osteomalacia/rickets (weak bones), hypoparathyroidism (low levels of parathyroid hormone), and tetany (a muscle disease with low blood calcium levels). Calcium carbonate is a mineral and prevents or treats calcium deficiency. It helps to maintain bone and teeth health. Calcitriol, a synthetic form of Vitamin D3, treats calcium deficiency with hypoparathyroidism (the parathyroid glands' decreased activity) and metabolic bone diseases in people with chronic kidney failure. Zinc is an important mineral in the normal growth and development of the skeletal system. It helps maintain bone density by increasing protein synthetase, which helps protect bone health.

Uses of Problast Capsule

Osteoporosis, Postmenopausal osteoporosis Osteomalacia, Rickets, Calcium deficiency and Tetany 

About Problast Capsule

Problast Capsule belongs to the class of ‘Multi-minerals’ primarily used to treat low blood calcium levels. Problast Capsule effectively treats various conditions caused by low calcium levels in the body, such as osteoporosis (weak and brittle bones), osteomalacia/rickets (weak bones), hypoparathyroidism (low levels of parathyroid hormone), and latent tetany (a muscle disease with low blood calcium levels). Problast Capsule can also be given to pregnant, nursing, and postmenopausal women to ensure that they are getting enough calcium. Additionally, Problast Capsule is used to treat hyperparathyroidism (overactive parathyroid glands) and metabolic bone disease in people with chronic kidney disease, surgery, or other conditions.

Problast Capsule consists of three medicines, namely: Calcium carbonate (mineral), Calcitriol (Vitamin D3), and  Zinc (mineral). Calcium is a mineral that is used to prevent or treat a calcium deficiency. It provides essential nutrients to maintain bone formation and maintenance. Calcitriol is a synthetic version of Vitamin D3 and treats calcium deficiency with hypoparathyroidism (the parathyroid glands' decreased activity) and metabolic bone diseases in people with chronic kidney failure. It raises Vitamin D levels and thereby increases calcium levels in the blood. This helps in improving the absorption rate of calcium from the intestine. Zinc is a mineral that has an essential role in bone health. Zinc helps to stimulate osteoblastic bone formation and mineralization.

Take Problast Capsule as instructed by your doctor. In some cases, Problast Capsule can cause side effects like constipation or stomach upset, nausea, vomiting, loss of appetite, mood changes, weakness, tiredness, fast or pounding heartbeat, bone/muscle pain, and headache. Most of these side effects of Problast Capsule do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

If you are known to be allergic to Problast Capsule or its inactive components, please inform your doctor. Pregnant or breastfeeding women should consult their doctor before taking Problast Capsule . Higher doses of Vitamin D than the recommended daily dose should be used in pregnant women only when advised by the doctor. Problast Capsule may pass into the breast milk. Hence breastfeeding mothers need to seek medical advice before starting Problast Capsule . Problast Capsule may contain sugar or sorbitol; hence caution should be taken to have sugar intolerance, diabetes, and phenylketonuria (increased levels of an amino acid called phenylalanine).

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Therapeutic Class

MULTIMINERALS

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