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  3. Promigra F 20mg/10mg Tablet

Written By Divya L , PharmaD
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
48 Hrs returnable
COD available

Online payment accepted

rxMedicinePrescription drug

Whats That

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Consume Type :

ORAL

Return Policy :

Not Returnable

Therapeutic Class

ANTIMIGRAINE AGENTS

Country of origin

India
Other Info - PR77677

Author Details

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FAQs

Promigra F 20mg/10mg Tablet is a combination of two drugs: Propranolol and Flunarizine. Promigra F 20mg/10mg Tablet treats migraine by reducing the blood flow to the brain, and inhibits cortical spreading depression, electrical activity in the brain that causes pain and inflammation.

Promigra F 20mg/10mg Tablet may sometimes cause weight gain during its prolonged use. It is always advised to maintain a well-balanced, healthy diet and exercise regularly.

Promigra F 20mg/10mg Tablet does not work for a sudden migraine attack. It is helpful in only preventing new episodes of migraine headaches. Please let your doctor know if you have sudden attacks to be prescribed other suitable medications.

Promigra F 20mg/10mg Tablet is contraindicated in asthma, slow heart rate, abnormal heart rhythms, heart conditions like AV (Atrioventricular) block or sick sinus syndrome, depression, and Parkinson's disease. Please consult your doctor before starting Promigra F 20mg/10mg Tablet if you have a medical history.

Your doctor will prescribe Promigra F 20mg/10mg Tablet to prevent any new episodes of migraine. Please do not stop taking this medicine unless advised by your doctor since it may lead to recurrent episodes of migraine. Promigra F 20mg/10mg Tablet also contains Propranolol, and its sudden withdrawal may cause sweating, shaking, irregular heartbeat, and worsening of underlying angina or heart attack. Hence, do not stop using Promigra F 20mg/10mg Tablet unless advised by your doctor.

Disclaimer

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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Promigra F 20mg/10mg Tablet. Alcohol intake, along with Promigra F 20mg/10mg Tablet, may cause increased dizziness and drowsiness.

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Pregnancy

Caution

Please consult your doctor if you are pregnant or planning to conceive before using Promigra F 20mg/10mg Tablet.

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Breast Feeding

Caution

Please consult your doctor before taking Promigra F 20mg/10mg Tablet if you are a lactating mother.

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Driving

Caution

Promigra F 20mg/10mg Tablet may make you feel drowsy. Do not drive or operate machinery if you experience drowsiness.

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Liver

Caution

Therapy with propranolol should be administered cautiously in patients with liver disease. Please consult your doctor if you have a history of liver impairment/liver disease.

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Kidney

Caution

Plasma clearance of Propranolol in Promigra F 20mg/10mg Tablet is reduced in patients with renal failure. Please consult your doctor if you have a history of kidney impairment/kidney disease.

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Children

Safe if prescribed

Promigra F 20mg/10mg Tablet is safe to use for children below 12 years of age when prescribed by the doctor.

About Promigra F 20mg/10mg Tablet

Promigra F 20mg/10mg Tablet belongs to the class of 'anti-migraine drugs' primarily used to treat migraine. Migraine is a medical condition that involves severe throbbing pain or a pulsing sensation on one side of the head. Severe and recurrent headaches are one of the characteristic symptoms of migraine. Its symptoms include nausea, vomiting, difficulty speaking, numbness or tingling, and sensitivity to light and sound.

Promigra F 20mg/10mg Tablet consists of 'Propranolol' (beta-blocker) and 'Flunarizine' (calcium channel blocker). Propranolol has anxiolytic (anxiety-reducing), anti-arrhythmic (treats abnormal heart rhythms), and antihypertensive (reduces blood pressure) properties. Propranolol works by reducing cerebral (brain) blood flow by directly acting on the brain's blood vessels. It also inhibits cortical spreading depression, electrical activity in the brain that causes pain and inflammation. It effectively treats and reduces the severity and frequency of migraine headaches. Flunarizine belongs to the class of calcium channel blockers. It improves blood flow and dilates blood vessels in the brain, thereby preventing headaches caused due to migraine. It is also used to treat vertigo (spinning sensation).

Your doctor will decide the dose and duration based on the severity of your pain. Common side effects of Promigra F 20mg/10mg Tablet include dry weight gain, slow heart rate, tiredness, depression, drowsiness, abnormal dreams, and cold extremities (hands and feet). These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Let your doctor know if you use any prescription and non-prescription medications you are taking, including other vitamins, before starting Promigra F 20mg/10mg Tablet. Promigra F 20mg/10mg Tablet may cause weight gain in some cases, so avoid eating junk and eat a healthy, balanced diet, including home-cooked food. Consult your doctor before taking Promigra F 20mg/10mg Tablet if you are pregnant, planning for pregnancy or breastfeeding. Avoid consuming alcohol along with Promigra F 20mg/10mg Tablet as it could lead to increased drowsiness.

Uses of Promigra F 20mg/10mg Tablet

Migraine.

Medicinal Benefits Mweb

Medicinal Benefits

Promigra F 20mg/10mg Tablet is used to treat migraine. It consists of 'Propranolol' and 'Flunarizine'. Propranolol is a beta-blocker and has anxiolytic (anxiety-reducing), anti-arrhythmic, and antihypertensive properties. It works by lowering cerebral (brain) blood flow and inhibits cortical spreading depression, electrical activity in the brain that causes pain and inflammation. It reduces the severity and frequency of migraine headaches. Flunarizine is a channel blocker that improves blood flow and dilates blood vessels in the brain, thereby preventing headaches caused due to migraine. 

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water; do not chew, crush or break it.

Side Effects of Promigra F 20mg/10mg Tablet

  • Weight gain
  • Slow heart rate
  • Tiredness
  • Depression
  • Drowsiness
  • Abnormal dreams
  • Cold extremities (hands and feet)

Drug Warnings

Inform your doctor if you have any history of liver or kidney diseases, breathing problems (asthma, bronchitis, emphysema), diabetes, heart failure, heart rhythm problems (sinus bradycardia, Wolff-Parkinson-White syndrome, atrioventricular block), overactive thyroid, blood circulation problems (Raynaud's disease), adrenal gland tumour (pheochromocytoma), depression, metabolic acidosis (excess acid in the blood), and myasthenia gravis (muscle weakness) before starting Promigra F 20mg/10mg Tablet. Please consult your doctor if you are pregnant and planning to conceive if the doctor advised you Promigra F 20mg/10mg Tablet. Avoid consuming alcohol along with Promigra F 20mg/10mg Tablet as it could lead to increased dizziness and drowsiness.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Promigra F 20mg/10mg Tablet:
Coadministration of thioridazine with Promigra F 20mg/10mg Tablet may increase the blood levels of thioridazine and cause an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is an interaction between Promigra F 20mg/10mg Tablet and thioridazine, they can be taken together if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, and shortness of breath contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Promigra F 20mg/10mg Tablet:
Taking atenolol and Promigra F 20mg/10mg Tablet together may lower your blood pressure excessively which may lead to side effects.

How to manage the interaction:
Combined use of atenolol and Promigra F 20mg/10mg Tablet may result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Promigra F 20mg/10mg Tablet:
Co-administration of Clonidine and Promigra F 20mg/10mg Tablet may lower blood pressure and slower heart rate.

How to manage the interaction:
Although there is a possible interaction between Clonidine and Promigra F 20mg/10mg Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience headaches, slow heartbeat, dizziness, or feeling like you might pass out, contact your doctor.
How does the drug interact with Promigra F 20mg/10mg Tablet:
Using Promigra F 20mg/10mg Tablet and verapamil together may lead to increased side effects.

How to manage the interaction:
Although taking Promigra F 20mg/10mg Tablet together with Verapamil can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fatigue, headache, fainting, swelling of the extremities, weight gain, shortness of breath, chest pain, increased or decreased heartbeat, or irregular heartbeat. Do not stop taking any medication without consulting a doctor.
How does the drug interact with Promigra F 20mg/10mg Tablet:
Using Promigra F 20mg/10mg Tablet together with terbutaline may reduce the benefits of both medications, since they have opposing effects in the body. In addition, Promigra F 20mg/10mg Tablet can sometimes cause breathing problems.

How to manage the interaction:
Although taking Promigra F 20mg/10mg Tablet together with Terbutaline can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Promigra F 20mg/10mg Tablet:
Using Promigra F 20mg/10mg Tablet together with Theophylline makes the Promigra F 20mg/10mg Tablet less effective in controlling blood pressure, and it also increases the effects of theophylline

How to manage the interaction:
Although taking Promigra F 20mg/10mg Tablet together with Theophylline can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, consult your doctor if you experience nausea, vomiting, sleeplessness, tremors, restlessness, irregular heartbeats, or difficulty breathing. Do not stop using any medication without consulting a doctor.
How does the drug interact with Promigra F 20mg/10mg Tablet:
Taking Promigra F 20mg/10mg Tablet with Labetalol can potentially enhance the effects of orthostatic hypotension (low blood pressure that happens when standing after sitting or lying down).

How to manage the interaction:
Although taking Promigra F 20mg/10mg Tablet together with Labetalol can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience lightheadedness or dizziness upon standing, blurred vision, weakness, fainting, or confusion. Do not discontinue any medicine without consulting a doctor.
PropranololIobenguane (131i)
Severe
How does the drug interact with Promigra F 20mg/10mg Tablet:
Coadministration of iobenguane (131i) and Promigra F 20mg/10mg Tablet may interfere with the effects of iobenguane I-131 in treating your condition.

How to manage the interaction:
Although there is a possible interaction between Promigra F 20mg/10mg Tablet and Iobenguane (131i), you can take these medicines together if prescribed by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Promigra F 20mg/10mg Tablet:
Co-administration of Bisoprolol with Promigra F 20mg/10mg Tablet may increase the risk or severity of adverse effects.

How to manage the interaction:
Although there may be an interaction, bisoprolol can be taken with Promigra F 20mg/10mg Tablet if prescribed by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
PropranololIndacaterol
Severe
How does the drug interact with Promigra F 20mg/10mg Tablet:
Using Promigra F 20mg/10mg Tablet together with indacaterol may reduce the benefits of both medications, since they have opposing effects in the body. In addition, Promigra F 20mg/10mg Tablet can cause breathing problems.

How to manage the interaction:
Although taking Promigra F 20mg/10mg Tablet together with Indacaterol can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • ALPRAZOLAM
  • QUETIAPINE
  • ARIPIPRAZOLE
  • ZOLPIDEM
  • DIPHENHYDRAMINE
  • SERTRALINE
  • DULOXETINE
  • FLUOXETINE
  • CARBAMAZEPINE
  • PHENYTOIN

Habit Forming

No

Special Advise

  • Let your doctor know that you are taking Promigra F 20mg/10mg Tablet if you are undergoing any medical tests.
  • Beta-blockers like Propranolol can mask hypoglycaemia symptoms (low blood sugar) or hyperthyroidism (high thyroid levels).
  • It is advised to inform your doctor if you have diabetes or thyroid disease before using Promigra F 20mg/10mg Tablet.
  • Beta-blockers can also cause changes in serum lipid profiles. Patients with pre-existing hyperlipidaemia (high lipid levels) should be closely monitored if using Promigra F 20mg/10mg Tablet.

Diet & Lifestyle Advise

  • Avoid chocolates, junk food, cheese, processed food, alcohol, and smoking. Instead, eat a healthy diet and do regular exercise to avoid weight gain caused due to Promigra F 20mg/10mg Tablet.
  • Avoid loud music, extreme temperatures, bright lights, and noisy places as it can increase headache.
  • You can try increasing your mindfulness by doing yoga, meditation, mindfulness-based cognitive therapy, and stress reduction techniques.
  • Drink enough water to stay hydrated and limit or avoid alcohol and caffeine to relieve headaches.
  • Include a diet rich in whole grains, vegetables, and fruits. This is a healthier option than eating a lot of simple carbohydrates found in processed foods.
  • You can include antioxidants in your daily diet like ashwagandha, omega-3 fatty acids, green tea, and lemon balm.
  • Try to spend time with your friends and family. Having a strong social network may help you lower your risk of anxiety.

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