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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

QUETIAPINE-300MG

Manufacturer/Marketer :

Crescent Formulations Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTIPSYCHOTICS

Country of origin

India
Other Info - PSY0068

FAQs

Psynil SR 300 mg Tablet contains 'quetiapine' that works by blocking dopamine receptors in the brain. By inhibiting the synthesis of the dopamine hormone, there will be a decrease in the occurrence of symptoms in patients with schizophrenia and bipolar depression. Psynil SR 300 mg Tablet  also has effects on other neurotransmitters in the brain, such as serotonin, and its beneficial effects may also be related to this. Altogether Psynil SR 300 mg Tablet  rebalances dopamine and serotonin to improve thinking, mood and behaviour.

Psynil SR 300 mg Tablet increases blood pressure. So, it is advisable to monitor your blood pressure while taking Psynil SR 300 mg Tablet frequently.

Psynil SR 300 mg Tablet may cause dizziness and may increase the risk of falls. So, stand up slowly when rising from a sitting or lying position.

Psynil SR 300 mg Tablet should not drive or operate heavy machinery after taking Psynil SR 300 mg Tablet as it causes drowsiness.

The long-term use of Psynil SR 300 mg Tablet may cause potential side effects such as tardive dyskinesia (uncontrolled movements of arms and legs), increased blood sugar, vision impairment, and weight gain. However, if the benefits outweigh the risks, your doctor prescribes Psynil SR 300 mg Tablet for a prolonged period.

Psynil SR 300 mg Tablet is not recommended for use in children and adolescents under the age of 18 years. In children, it may cause potential side effects such as swelling of breasts in boys and girls, irregular periods and weight gain.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

Alcohol may worsen the condition and increase the risk of side effects while using Psynil SR 300 mg Tablet .

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Pregnancy

Caution

Psynil SR 300 mg Tablet is a category C medicine. It should be used in pregnant women only when prescribed by a doctor.

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Breast Feeding

Caution

Psynil SR 300 mg Tablet should not be given to breastfeeding mothers unless prescribed by a doctor.

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Driving

Caution

Psynil SR 300 mg Tablet may cause dizziness. So, it is not recommended to drive or operate heavy machinery when you take Psynil SR 300 mg Tablet .

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Liver

Caution

Psynil SR 300 mg Tablet should be used with caution in patients with liver diseases. Dose adjustments may be necessary.

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Kidney

Caution

Psynil SR 300 mg Tablet should be used with caution in patients with kidney diseases. Dose adjustments may be necessary.

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Children

Unsafe

Psynil SR 300 mg Tablet is not recommended for use in children under 12 years of age.

About Psynil SR 300 mg Tablet

Psynil SR 300 mg Tablet belongs to a group of medications called ‘antipsychotics’. It is used in the treatment of bipolar depression, mania and schizophrenia. Bipolar disorder is characterized by manic episodes of excitement or euphoria and depression. Schizophrenia is characterized by symptoms of hallucinations (seeing or hearing things that are not real) and delusions (wrong beliefs).

Psynil SR 300 mg Tablet contains ‘quetiapine’, which is an antipsychotic drug. It acts by blocking dopamine, a hormone in the brain responsible for developing symptoms of schizophrenia and bipolar disorder. Psynil SR 300 mg Tablet  also affects other neurotransmitters in the brain, such as serotonin, and its beneficial effects may also be related to this. Altogether  Psynil SR 300 mg Tablet  rebalances dopamine and serotonin to improve thinking, mood and behaviour.

Psynil SR 300 mg Tablet should be taken as prescribed by the doctor. Common side-effects of Psynil SR 300 mg Tablet are dizziness, drowsiness, headache, dry mouth, abnormal muscle movements such as difficulty moving muscles, tremors and muscle stiffness,  change in cholesterol levels, weight gain, and decrease in haemoglobin (protein in blood that carries oxygen) levels. Additionally, in children and adolescents, swelling of breasts in boys and girls and production of breast milk (due to an increase in prolactin hormone (helps in producing breast milk)) and irregular menstruation can be seen. Please do not stop taking Psynil SR 300 mg Tablet without your doctor’s advice, as it may lead to withdrawal symptoms.

Do not take Psynil SR 300 mg Tablet if you are allergic to quetiapine or any other ingredients present in it. Before taking Psynil SR 300 mg Tablet , inform your doctor if you have problems associated with the liver, kidney or heart. Also, inform your doctor if you have any sleeping difficulties. It is not recommended for use in children under 18 years of age. Tell your doctor immediately if you develop suicidal thoughts, or your depression worsens after taking Psynil SR 300 mg Tablet . Psynil SR 300 mg Tablet contains lactose, so it should not be given to people who are intolerant to some sugars. Tell your doctor if you are pregnant or breastfeeding.

Uses of Psynil SR 300 mg Tablet

Bipolar depression, mania, schizophrenia

Medicinal Benefits Mweb

Medicinal Benefits

Psynil SR 300 mg Tablet contains ‘quetiapine’ that belongs to the class of antipsychotics. It works by blocking the dopamine receptors preventing the excessive activity of dopamine. Dopamine is a ‘feel-good hormone’ that promotes happiness, excitement and pleasure. It alters brain function, improving mood, thinking ability and social behaviour. It reduces the development of symptoms in patients with schizophrenia, bipolar disorder or other mood disorders. Psynil SR 300 mg Tablet  also has effects on other neurotransmitters in the brain, such as serotonin, and its beneficial effects may also be related to this. Altogether  Psynil SR 300 mg Tablet  rebalances dopamine and serotonin to improve thinking, mood and behaviour.

Directions for Use

Tablet: Swallow it as a whole with water; do not crush, break or chew it.Oral Suspension/syrup: Shake the bottle well before each use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper.

Drug Warnings

Do not take Psynil SR 300 mg Tablet if you are allergic to quetiapine or any ingredients present in it. Before taking Psynil SR 300 mg Tablet , inform your doctor if you have low blood pressure, stroke, liver problems, seizures, diabetes, dementia (memory loss), alcohol or drug abuse, sleep apnea (a sleep disorder) and urinary retention. Psynil SR 300 mg Tablet contains lactose, so it should not be given to people with lactose intolerance. Do not abruptly stop taking the medication as it may cause withdrawal symptoms, especially suicidal thoughts in young adults.

Drug-Drug Interactions

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QuetiapineZiprasidone
Critical
QuetiapineMetoclopramide
Critical

Drug-Drug Interactions

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QuetiapineZiprasidone
Critical
How does the drug interact with Psynil SR 300 mg Tablet:
Co-administration of Psynil SR 300 mg Tablet with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Psynil SR 300 mg Tablet with Ziprasidone together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
QuetiapineMetoclopramide
Critical
How does the drug interact with Psynil SR 300 mg Tablet:
Coadministration of metoclopramide with Psynil SR 300 mg Tablet can increase the risk of side effects like uncontrolled movement disorder.

How to manage the interaction:
Taking Metoclopramide with Psynil SR 300 mg Tablet is generally avoided as it can possibly result in an interaction. They can be taken together if advised by your doctor. However, contact a doctor if you experience any symptoms like muscle spasms or movements that you can't stop or control, such as lip smacking, chewing, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, restlessness, pacing, and foot tapping. Do not stop taking any medications without consulting a doctor.
QuetiapineArsenic trioxide
Severe
How does the drug interact with Psynil SR 300 mg Tablet:
Coadministration of Psynil SR 300 mg Tablet with arsenic trioxide can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Co-administration of Arsenic trioxide with Psynil SR 300 mg Tablet can possibly result in an interaction, they can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
QuetiapinePhenobarbital
Severe
How does the drug interact with Psynil SR 300 mg Tablet:
Coadministration of Psynil SR 300 mg Tablet and phenobarbital may significantly reduce the blood levels of Psynil SR 300 mg Tablet, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although taking phenobarbital and Psynil SR 300 mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without first talking to a doctor.
QuetiapineGatifloxacin
Severe
How does the drug interact with Psynil SR 300 mg Tablet:
Taking gatifloxacin and Psynil SR 300 mg Tablet can increase the risk or severity of an irregular heart rhythm.

How to manage the interaction:
Taking gatifloxacin and Psynil SR 300 mg Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, severe or prolonged diarrhea or vomiting, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
QuetiapineSotalol
Severe
How does the drug interact with Psynil SR 300 mg Tablet:
Using sotalol together with Psynil SR 300 mg Tablet can increase the risk or severity of irregular heart rhythms which can be severe.

How to manage the interaction:
Although there is a possible interaction between Sotalol and Psynil SR 300 mg Tablet, you can take these medicines together if prescribed by a doctor. If you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations consult a doctor. Do not stop using any medications without talking to a doctor.
QuetiapineHaloperidol
Severe
How does the drug interact with Psynil SR 300 mg Tablet:
Coadministration of Psynil SR 300 mg Tablet and haloperidol can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Co-administration of Psynil SR 300 mg Tablet and haloperidol can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
QuetiapineOxycodone
Severe
How does the drug interact with Psynil SR 300 mg Tablet:
Coadministration of Psynil SR 300 mg Tablet with oxycodone can increase the risk and severity of side effects.

How to manage the interaction:
Co-administration of Psynil SR 300 mg Tablet with Oxycodone can possibly result in an interaction, they can be taken together if prescribed by a doctor. However, consult your doctor if you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment. Do not discontinue any medications without consulting a doctor.
QuetiapineClarithromycin
Severe
How does the drug interact with Psynil SR 300 mg Tablet:
Co-administration of clarithromycin with Psynil SR 300 mg Tablet may increase the blood levels and effects of Psynil SR 300 mg Tablet.

How to manage the interaction:
Although there is a possible interaction, clarithromycin can be taken with Psynil SR 300 mg Tablet if prescribed by the doctor. Consult the prescriber if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or fast or pounding heartbeats during treatment with these medications. Do not stop using any medications without a doctor's advice.
QuetiapineKetoconazole
Severe
How does the drug interact with Psynil SR 300 mg Tablet:
Coadministration of Psynil SR 300 mg Tablet and Ketoconazole may increase the blood levels of Psynil SR 300 mg Tablet.

How to manage the interaction:
Although taking ketoconazole and Psynil SR 300 mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, tiredness, dry mouth, constipation, increased hunger, or weight gain, contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • CITALOPRAM
  • ESCITALOPRAM
  • BUPROPION
  • ACETAMINOPHEN
  • HYDROCODONE
  • TRAMADOL

Habit Forming

No

Special Advise

  • Psynil SR 300 mg Tablet may increase blood sugar levels even if you don't have diabetes, especially in patients with schizophrenia. So, it is recommended to immediately inform your doctor if you have symptoms such as increased thirst, frequent urination, fatigue or increased appetite.
  • If you are having a urine drug screen (an analysis to determine the presence of illegal drugs or drugs that are mostly abused, such as methadone or tricyclic antidepressants in the blood), the test results may show positive when certain test methods are used. A more specific test may be required in such cases.

Diet & Lifestyle Advise

  • Do not take grapefruit or grapefruit juice while using Psynil SR 300 mg Tablet as it may alter the effects of the medicine.
  • Avoid intense exercise as it is harder for the body to cool down when it gets very hot. So, drink plenty of fluids and avoid going out in hot weather.
  • Do not take alcohol as it increases drowsiness and also worsens the disease condition. 
  • Eat healthily and keep a check on your weight regularly.

Psynil SR 300 mg Tablet Substitute

Substitutes safety advice
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