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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
COD available

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Manufacturer/Marketer :

Suzikem Drugs Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Pymet 5mg/500mg Tablet

Pymet 5mg/500mg Tablet belongs to the group of medicines called anti-migraine agents used to treat signs of migraine such as headache, being sick (vomiting), and feeling sick (nausea). Migraine is a neurological condition which is characterised by an intense pulsating, throbbing, pounding, debilitating headache which generally occurs on one side of the head; however, it can occur on both sides or shift.

Pymet 5mg/500mg Tablet is a combination of two drugs: Metoclopramide (anti-emetics) and Paracetamol (analgesics). Metoclopramide works on the part of the brain and prevents the symptoms of nausea and vomiting. It also works on the muscles in the upper part of the digestive system, this helps in emptying the stomach. Paracetamol works by blocking the effect of a chemical messenger known as prostaglandins which cause pain. Together Pymet 5mg/500mg Tablet helps in relieving the symptoms of migraine.

Take Pymet 5mg/500mg Tablet as prescribed. You are advised to take Pymet 5mg/500mg Tablet for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as dizziness, sleepiness, diarrhoea, irregular periods, weakness, nervousness and breast enlargement in men. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Consult your doctor before taking Pymet 5mg/500mg Tablet if you are pregnant or breastfeeding. Pymet 5mg/500mg Tablet should not be taken during the first 6 months of pregnancy. Pymet 5mg/500mg Tablet may cause drowsiness and sleepiness, so drive with caution. Pymet 5mg/500mg Tablet is not recommended for children below 18 years as safety and efficacy have not been established. Avoid consuming alcohol with Pymet 5mg/500mg Tablet as it could lead to increased drowsiness and sleepiness. Inform your doctor about your health condition and medicines you are taking to rule out unpleasant side-effects. 

Uses of Pymet 5mg/500mg Tablet

Migraine

Directions for Use

Tablet/capsule: Swallow it as a whole with water; do not crush, break or chew it.Syrup: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Medicinal Benefits

Pymet 5mg/500mg Tablet is a combination of two drugs, namely: Metoclopramide and Paracetamol. Pymet 5mg/500mg Tablet is used to treat migraine signs such as headache, being sick (vomiting) and feeling sick (nausea). Metoclopramide is an anti-emetic that works on the part of the brain, thereby prevents the symptoms of nausea and vomiting. It also works on the muscles in the upper part of the digestive system, this helps in the emptying of the stomach. Paracetamol is an analgesic that works by blocking the effect of a chemical messenger known as prostaglandins which cause pain. Thereby, helps in relieving pain. Together Pymet 5mg/500mg Tablet helps relieve the symptoms of migraine such as headache, nausea and vomiting.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Pymet 5mg/500mg Tablet if you are allergic to any of its contents; if you have/had blockage or bleeding in your stomach, epilepsy/fits, phaeochromocytoma (tumour of the adrenal gland), uncontrollable movements of the face, arms or legs after taking metoclopramide or medicines used to calm mental problems, if you had an operation on stomach or intestine or if you are taking levodopa. Inform your doctor before taking Pymet 5mg/500mg Tablet if you have/had severe kidney or liver problems; if you are 65 years or older. Consult your doctor if you are pregnant or breastfeeding. Pymet 5mg/500mg Tablet should not be taken during the first 6 months of pregnancy.  Pymet 5mg/500mg Tablet may cause sleepiness and dizziness, so drive only if you are alert. Pymet 5mg/500mg Tablet is not recommended for children below 18 years as safety and effectiveness have not been established. Avoid consuming alcohol with Pymet 5mg/500mg Tablet as it could lead to increased sleepiness. Pymet 5mg/500mg Tablet contains paracetamol, do not take any other medicines containing paracetamol along with Pymet 5mg/500mg Tablet unless prescribed.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Pymet 5mg/500mg Tablet:
Coadministration of Pymet 5mg/500mg Tablet with Pimozide can increase the risk of negative side effects.

How to manage the interaction:
Taking Pimozide with Pymet 5mg/500mg Tablet is not recommended, as it can possibly lead to an interaction, but it can be taken if prescribed by the doctor. However, if you experience muscle pain or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping, consult a doctor. Do not stop using any medications without a doctor’s advice.
How does the drug interact with Pymet 5mg/500mg Tablet:
Taking Pymet 5mg/500mg Tablet with Amisulpride may increase the risk or severity of side effects.

How to manage the interaction:
Taking Amisulpride with Pymet 5mg/500mg Tablet is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you have muscle spasms or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Pymet 5mg/500mg Tablet:
Taking Methyldopa and Pymet 5mg/500mg Tablet together can decrease the levels and effects of Methyldopa.

How to manage the interaction:
Taking Pymet 5mg/500mg Tablet with Methyldopa is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Pymet 5mg/500mg Tablet:
Coadministration of Pymet 5mg/500mg Tablet with duloxetine increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Pymet 5mg/500mg Tablet with Duloxetine is not recommended, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Pymet 5mg/500mg Tablet:
The combination of Lurasidone and Pymet 5mg/500mg Tablet may result in significantly increased Lurasidone blood levels. This may raise the possibility of undesirable consequences such as Parkinson's disease. (It is a neurological condition that causes uncontrollable movements)and Tardive dyskinesia (uncontrollable movements, particularly of the lower face).

How to manage the interaction:
Lurasidone and Pymet 5mg/500mg Tablet is not recommended, as they may interact, but can be used if a doctor prescribes them. Consult a doctor if you have muscle spasms, or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning, tongue thrusting, teeth clenching, jaw twitching, jitteriness, restlessness, pacing, and foot tapping. Do not stop taking any medications without visiting a doctor.
How does the drug interact with Pymet 5mg/500mg Tablet:
Coadministration of Pymet 5mg/500mg Tablet and prochlorperazine can increase the risk of side effects.

How to manage the interaction:
Taking Pymet 5mg/500mg Tablet with Prochlorperazine together is generally avoided as it can possibly result in an interaction, they can be taken together if advised by your doctor. However, if you experience muscle spasm or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping, consult the doctor. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Pymet 5mg/500mg Tablet:
Co-administration of Pymet 5mg/500mg Tablet with Bupropion can increase the levels of Pymet 5mg/500mg Tablet and increase the risk or severity of developing seizures (fits).

How to manage the interaction:
Taking Pymet 5mg/500mg Tablet with Bupropion is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
MetoclopramideNefazodone
Critical
How does the drug interact with Pymet 5mg/500mg Tablet:
Coadministration of Pymet 5mg/500mg Tablet with Nefazodone can cause serotonin syndrome. Serotonin syndrome is a condition in which a chemical called serotonin builds up in your body, causing signs and symptoms ranging from mild (shivering and diarrhoea) to severe (muscle rigidity, fever, and seizures).

How to manage the interaction:
Taking Pymet 5mg/500mg Tablet with Nefazodone is generally avoided as it can possibly lead to an interaction, it can be taken if prescribed by your doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, incoordination, stomach pain, nausea, vomiting, and diarrhoea, consult the doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Pymet 5mg/500mg Tablet:
Co-administration of Pymet 5mg/500mg Tablet with Clozapine can increase the risk of side effects.

How to manage the interaction:
Taking Pymet 5mg/500mg Tablet with Clozapine is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Pymet 5mg/500mg Tablet:
Coadministration of Pymet 5mg/500mg Tablet with quetiapine can increase the risk of side effects like uncontrolled movement disorder.

How to manage the interaction:
Taking Pymet 5mg/500mg Tablet with Quetiapine is generally avoided as it can possibly result in an interaction. They can be taken together if advised by your doctor. However, contact a doctor if you experience any symptoms like muscle spasms or movements that you can't stop or control, such as lip smacking, chewing, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, restlessness, pacing, and foot tapping. Do not stop taking any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly as it helps in improving overall health and boosts self-esteem.
  • Avoid bright lights, loud noise, and extreme temperatures.
  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.
  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.
  • Massage your scalp to ease the pain.
  • Lie down in a quiet, dark room.
  • Place a cold cloth over your forehead or neck.
  • Avoid smoking, alcohol, and caffeinated drinks. 
  • Learn what triggers your migraine and try avoiding them.
  • Stay hydrated. Drink plenty of fluids.
  • Learn relaxation skills as they help in reducing stress.

Habit Forming

No

Therapeutic Class

ANTIMIGRAINE AGENTS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Pymet 5mg/500mg Tablet contains Metoclopramide and Paracetamol. Metoclopramide works on the part of the brain, thereby prevents the symptoms of nausea and vomiting. It also works on the muscles in the upper part of the digestive system, this helps in emptying the stomach. Paracetamol works by blocking the effect of a chemical messenger known as prostaglandins which cause pain. Thereby, helps in relieving pain.

Consult your doctor before taking oral contraceptive pills along with Pymet 5mg/500mg Tablet as they might decrease the effectiveness of Pymet 5mg/500mg Tablet. Talk to your doctor, he/she may advise you to use an alternate method of contraception.

Pymet 5mg/500mg Tablet contains Paracetamol, an analgesic used to provide relief from pain. Therefore, please consult your doctor before taking any pain killer medicines, fever-reducing medicines, medicines for cold or sleeping problems along with Pymet 5mg/500mg Tablet as they may also contain paracetamol.

If you had an operation on your stomach or intestine, do not take Pymet 5mg/500mg Tablet during the first 3-4days after the surgery. However, please talk to your doctor before taking Pymet 5mg/500mg Tablet if you have had surgery.

Diarrhoea could be a side-effect of Pymet 5mg/500mg Tablet. Drink plenty of liquids to replace the lost fluids if you experience diarrhoea. Consult your doctor if the condition persists or worsens.

Pymet 5mg/500mg Tablet may cause irregular periods or loss of periods. Please consult your doctor if you experience this for longer than a few days.

Drug-Drug Interactions Checker List

  • LEVODOPA
  • MIRTAZAPINE
  • TRAZODONE
  • CHLORAMPHENICOL
  • WARFARIN
  • CYCLOSPORINE
  • CLONIDINE
  • CODEINE
  • CHLORPHENIRAMINE
  • PROMETHAZINE
  • DIGOXIN
  • DOMPERIDONE
  • CHOLESTYRAMINE
  • MEBEVERINE
  • HYOSCYAMINE
  • OXYBUTYNIN
  • TOLTERODINE
  • DIHYDROCODEINE
  • DEXTROPROPOXYPHENE
  • PROPIVERINE

Special Advise

Metoclopramide in Pymet 5mg/500mg Tablet may decreases the gastric absorption of digoxin. Therefore, inform your doctor if you take digoxin.

Disease/Condition Glossary

Migraine: Migraine is a neurological condition which is characterised by an intense, debilitating headache. Hormonal changes, stress, lack or excess of sleep, bright lights, loud sounds, certain foods and drinks can trigger migraine headaches. Warning symptoms precede migraine headache one or two days before the headache itself. The warning symptoms include food cravings, depression, fatigue, hyperactivity, irritability and neck stiffness. Symptoms of migraine include throbbing pain in one particular area with varying intensity, nausea, vomiting, numbness or tingling sensation, difficulty speaking, sensitivity to sound and light.

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