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Written By Divya L , PharmaD
Reviewed By Sunny S , MBBS
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Manufacturer/Marketer :

Saffron Therapeutics Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

GASTROINTESTINAL AGENTS

Country of origin

India

Manufacturer/Marketer address

4603/2, Shanti Estate, Ghanshyam Estate,Aslali, Ta Daskroi ,Ahmedabad -382425.
Other Info - RAF0043

Author Details

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FAQs

Rafron Total Tablet works by reducing the amount of acid produced in the stomach and blocks the action of certain chemical messengers that trigger nausea and vomiting. Thus, Rafron Total Tablet relieves stomach ulcers, heartburn, GERD, nausea, vomiting and other gastrointestinal discomforts.

Rafron Total Tablet should be used with caution and only under doctor’s supervision if you have any liver, kidney or heart diseases, stomach and intestinal problems, recent abdominal surgery, Vitamin B12 deficiency, risk of bone fractures and autoimmune diseases like lupus.

Talk to your doctor if you do not feel better even after taking Rafron Total Tablet for 14 days. Do not take Rafron Total Tablet for longer durations unless prescribed by the doctor. If Rafron Total Tablet is prescribed for longer durations, a regular check-up is advised.

Antacids do not interfere with the absorption of Rafron Total Tablet . However, it is advised to take antacid and Rafron Total Tablet at different times. Please seek medical advice on how to use other medicines like antacids while using Rafron Total Tablet .

Diarrhoea might be a side-effect of Rafron Total Tablet . Drink lots of fluids and eat foods rich in fibre if you experience diarrhoea. If you find blood in stools (tarry stools) or experience excess diarrhoea, consult your doctor. Prolonged intake of Rafron Total Tablet is linked with a greater risk of Clostridium difficile-associated diarrhoea, so if you develop diarrhoea that does not improve, immediately consult a doctor.

On long term treatment, Rabeprazole in Rafron Total Tablet may increase the risk of fractures of the hip, spine, and wrist. Inform your doctor if you have osteoporosis, bone-related problems, or taking any corticosteroids. Your doctor may suggest supplements like Calcium citrate and Vitamin D.

Rabeprazole in Rafron Total Tablet may cause low Vitamin B12 levels on long term usage. Your doctor may adjust the dose of Rafron Total Tablet accordingly and may also suggest Vitamin B12 supplements.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

Alcohol consumption may increase acid production in the stomach. It is advised to avoid alcohol intake to prevent any undesirable side effects of Rafron Total Tablet and further worsening of your disease. Please consult your doctor for more information before using Rafron Total Tablet .

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Pregnancy

Caution

Rafron Total Tablet is not recommended for use in pregnancy since Ondansetron may cause harmful effects on the developing baby. It is advised to consult your doctor if you plan to conceive or already pregnant before starting Rafron Total Tablet .

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Breast Feeding

Caution

It is not known if Rafron Total Tablet passes into breast milk. Please consult your doctor before taking Rafron Total Tablet if you are a nursing mother.

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Driving

Safe if prescribed

Rafron Total Tablet is probably safe to use and doesn’t affect driving. However, please do not drive or operate machines if you experience any side effects that affect your ability to drive.

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Liver

Caution

Let your doctor know if you have any history of liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Rafron Total Tablet .

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing Rafron Total Tablet .

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Children

Caution

Ondansetron in Rafron Total Tablet may not be suitable for children below four years of age. Please consult your doctor before giving Rafron Total Tablet to your child. Your doctor will decide the dose and duration based on your child’s age and medical condition.

About Rafron Total Tablet

Rafron Total Tablet is a gastrointestinal medication, primarily used to treat nausea, vomiting, stomach ulcers, gastro-oesophageal reflux disease (GERD), heartburn, and erosive oesophagitis (acid-related damage to the lining of the oesophagus). Rafron Total Tablet is also used to treat infections caused by Helicobacter pylori and Zollinger-Ellison syndrome. GERD is a condition that occurs when stomach acid frequently flows back into the food pipe (oesophagus). Zollinger Ellison syndrome is a rare condition in which a gastrin-secreting tumour of the pancreas causes excessive acid production leading to peptic ulcers.

Rafron Total Tablet contains two medicines: Rabeprazole and Ondansetron. Rabeprazole belongs to the group of drugs called ‘proton pump inhibitors.’ It blocks the action of the gastric proton pump that is responsible for the production of acid in the stomach. This reduces the amount of acid produced, heals the ulcers, and prevents the formation of new ulcers. Ondansetron belongs to the class of anti-emetics (prevents vomiting). It works by blocking the action of serotonin (chemical messenger) that triggers nausea and vomiting.

Take Rafron Total Tablet as advised by the doctor. Your doctor will advise the appropriate dose that suits your medical condition. Common side effects of Rafron Total Tablet include nausea, vomiting, constipation, headache, fatigue, diarrhoea, sore throat, and abdominal pain. These side effects may not occur in every patient using this medication and differ individually. If the side effects persist longer or worsen, please seek a doctor’s advice.

Let your doctor know if you are sensitive or allergic to Rafron Total Tablet or any other medications. Before using Rafron Total Tablet , let your doctor know if you have any liver, kidney or heart diseases, and gastrointestinal problems. Pregnant and breastfeeding women should consult their doctor before using Rafron Total Tablet . Avoid alcohol intake while using Rafron Total Tablet since it can increase acid production in the stomach. Ondansetron in Rafron Total Tablet is not recommended for children below four years of age.

Uses of Rafron Total Tablet

Nausea, vomiting, stomach ulcers, gastro-oesophageal reflux disease (GERD), heartburn, erosive oesophagitis, and Zollinger-Ellison syndrome.

Medicinal Benefits Mweb

Medicinal Benefits

Rafron Total Tablet is used to treat nausea, vomiting, stomach ulcers, gastro-oesophageal reflux disease (GERD), heartburn and erosive oesophagitis. It contains Rabeprazole and Ondansetron. Rabeprazole is a proton pump inhibitor that blocks the action of the gastric proton pump that is responsible for acid production in the stomach. Ondansetron is an anti-emetic drug. It works by blocking the action of serotonin (chemical messenger) that triggers nausea and vomiting. Thus, collectively Rafron Total Tablet prevents nausea and vomiting, reduces the amount of acid produced, heals the ulcers, and prevents new ulcers. Rafron Total Tablet is also used to treat infections caused by Helicobacter pylori and Zollinger-Ellison syndrome.

Directions for Use

Swallow Rafron Total Tablet as a whole with a glass of water. You can take it with or without food at regular intervals, as prescribed by the doctor. Do not crush, chew or break it.

Side Effects of Rafron Total Tablet

  • Nausea
  • Vomiting
  • Constipation
  • Headache
  • Fatigue
  • Diarrhoea
  • Sore throat
  • Abdominal pain

Drug Warnings

Let your doctor know if you are sensitive to Rafron Total Tablet or its components. Rafron Total Tablet should be used with caution and only under doctor’s supervision if you have stomach/intestinal problems, liver, kidney or heart diseases, recent abdominal surgery, risk of bone fractures and autoimmune diseases like lupus. Long term treatment with Rafron Total Tablet may increase the risk of fractures of the hip, spine, and wrist. Hence, inform your doctor if you have osteoporosis, bone-related problems, or taking any corticosteroids before starting Rafron Total Tablet . Let your doctor know if you are pregnant or a nursing mother before starting Rafron Total Tablet . Avoid alcohol intake while using Rafron Total Tablet since it can increase acid production in the stomach.

Drug-Drug Interactions

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OndansetronZiprasidone
Critical
RabeprazoleRilpivirine
Critical

Drug-Drug Interactions

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OndansetronZiprasidone
Critical
How does the drug interact with Rafron Total Tablet:
Taking Rafron Total Tablet with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Rafron Total Tablet with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
RabeprazoleRilpivirine
Critical
How does the drug interact with Rafron Total Tablet:
Co-administration of Rafron Total Tablet can make Rilpivirine less effective by reducing its absorption in the body.

How to manage the interaction:
Taking Rafron Total Tablet with Rilpivirine is not recommended, but can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
RabeprazoleErlotinib
Critical
How does the drug interact with Rafron Total Tablet:
When used in combination with erlotinib, Rafron Total Tablet may prevent the absorption of erlotinib into the circulation, which might make erlotinib less effective in treating cancer.

How to manage the interaction:
Taking Rafron Total Tablet with Erlotinib is not recommended as it can result in an interaction, it should be taken only if a doctor has advised it. Do not stop using any medications without consulting a doctor.
OndansetronOsimertinib
Severe
How does the drug interact with Rafron Total Tablet:
Taking Rafron Total Tablet with Osimertinib increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Rafron Total Tablet along with Osimertinib can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without a doctor's advice.
OndansetronRibociclib
Severe
How does the drug interact with Rafron Total Tablet:
Taking Rafron Total Tablet with ribociclib increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Rafron Total Tablet along with ribociclib can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without a doctor's advice.
OndansetronFentanyl
Severe
How does the drug interact with Rafron Total Tablet:
Taking fentanyl with Rafron Total Tablet may increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although taking fentanyl with Rafron Total Tablet can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience confusion, hallucinations (seeing and hearing things that do not exist), increased heart rate, fever, excessive sweating, muscle pain or stiffness, stomach cramps, vomiting, or diarrhoea, consult a doctor. Do not discontinue any medications without consulting your doctor.
OndansetronBedaquiline
Severe
How does the drug interact with Rafron Total Tablet:
Taking Rafron Total Tablet with bedaquiline increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Rafron Total Tablet along with bedaquiline can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, get medical help immediately. Do not discontinue any medications without a doctor's advice.
OndansetronToremifene
Severe
How does the drug interact with Rafron Total Tablet:
Taking Rafron Total Tablet with toremifene increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Although taking Rafron Total Tablet along with toremifene can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without a doctor's advice.
OndansetronVilazodone
Severe
How does the drug interact with Rafron Total Tablet:
When Vilazodone is taken with Rafron Total Tablet, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in body).

How to manage the interaction:
There may be a possibility of interaction between Vilazodone and Rafron Total Tablet, but it can be taken if prescribed by a doctor. If you notice any of these signs - like confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea-call a doctor right away. Do not stop using any medications without a doctor's advice.
OndansetronPentazocine
Severe
How does the drug interact with Rafron Total Tablet:
Taking Pentazocine with Rafron Total Tablet may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increase in body).

How to manage the interaction:
Taking Rafron Total Tablet with Pentazocine together can result in an interaction but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination (seeing and hearing things that do not exist), fits, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • ACETAMINOPHEN
  • IBUPROFEN
  • PREGABALIN
  • DIAZEPAM
  • APOMORPHINE
  • DULOXETINE
  • CLOPIDOGREL
  • LEVOTHYROXINE
  • ATAZANAVIR
  • KETOCONAZOLE
  • METHOTREXATE
  • CYANOCOBALAMIN

Habit Forming

No

Special Advise

  • It is advised to monitor your blood pressure and blood glucose levels regularly while using Rafron Total Tablet .
  • Your doctor may suggest diagnostic procedures like endoscopy or colonoscopy to understand your disease and its severity.
  • Rafron Total Tablet may cause abnormal blood and liver enzyme tests. Inform your doctor and laboratory staff that you are taking Rafron Total Tablet before undergoing any examinations.

Diet & Lifestyle Advise

  • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increases acidity and heartburn.
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
  • Limit taking high fibre foods, foods and drinks that contain chocolate, alcohol, caffeine, fructose, or sorbitol, carbonated drinks, fried, and fatty foods. 
  • Do not have large meals at a time, instead try having small and simpler meals at regular intervals, including fresh fruits and vegetables in your diet.
  • Practice yoga and recreation techniques to manage your emotional stress.
  • If you are lactose intolerant, avoid using dairy products since it can worsen your stomach discomforts.
  • If you cannot take dairy products, it is advised to include other calcium-rich foods like leafy greens, beans, nuts, and seeds.
  • Drink plenty of fluids to prevent dehydration.

Rafron Total Tablet Substitute

Substitutes safety advice
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