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  3. Refra 2.5 Tablet 15's

Not for online sale
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Sureshvarma D , MPharma
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

MIDODRINE-2.5MG

Manufacturer/Marketer :

Sanfegan Biotech Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Therapeutic Class

ANTIHYPOTENSIVES

Country of origin

India

Manufacturer/Marketer address

Wall Frames,2B, Ayyappankavu, Kochi, Kerala 682018
Other Info - REF0142

Author Details

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FAQs

Refra 2.5 Tablet 15's contains the active ingredient midodrine hydrochloride, which acts on the blood vessels via the sympathetic nervous system to correct imbalances of blood distribution. This should help relieve the symptoms you might suffer, such as dizziness, fainting, blurred vision, and weakness when sitting or standing up.

Do not stop taking Refra 2.5 Tablet 15's on your own. Depending on your medical condition, you are advised to take Refra 2.5 Tablet 15's for as long as your doctor has prescribed it for you. Do not hesitate to speak with your doctor if you experience difficulty while taking Refra 2.5 Tablet 15's.

Do not take Refra 2.5 Tablet 15's if you are pregnant or planning for pregnancy unless prescribed by a doctor. Your doctor will prescribe Refra 2.5 Tablet 15's only if the benefits outweigh the risks.

Refra 2.5 Tablet 15's is contraindicated in patients with severe organic heart disease, congestive heart failure, thyrotoxicosis, phaeochromocytoma, acute renal disease, severe renal insufficiency, urinary retention, narrow-angle glaucoma, hyperthyroidism, known hypersensitivity to any component of the product. And also, Patients with a history of CVA should be monitored closely.

Refra 2.5 Tablet 15's is metabolised to desglymidodrine, an active metabolite that activates alpha-1-adrenergic receptors on arterioles and venules, causing smooth muscle contraction and blood pressure increase. Midodrine may cause a drop in heart rate due to the vagal reflex.

Disclaimer

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Alcohol

Caution

Consuming alcohol along with Refra 2.5 Tablet 15's is not advisable as it may cause unpleasant side effects.

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Pregnancy

Caution

Please consult the doctor. There are no adequate and well-controlled studies on pregnant women. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor, and there is no substantial research yet on the use of Refra 2.5 Tablet 15's in breastfeeding/nursing mothers.

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Driving

Caution

Patients who experience dizziness or lightheadedness while receiving Midodrine should refrain from operating machinery.

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Liver

Caution

Limited information is available on the use of Refra 2.5 Tablet 15's in patients with liver disease. Your doctor will weigh the benefits and potential risks before prescribing them. Please consult your doctor.

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Kidney

Caution

Limited information is available on the use of Refra 2.5 Tablet 15's in patients with Kidney disease. Your doctor will weigh the benefits and potential risks before prescribing them. Please consult your doctor.

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Children

Unsafe

Refra 2.5 Tablet 15's is not recommended for children below 18 years of age.

About Refra 2.5 Tablet 15's

Refra 2.5 Tablet 15's belongs to a category of medications called ‘Antihypotensives’ primarily used to treat hypotension (low blood pressure). Hypotension is when blood pressure drops below the normal range, reducing cardiac output and hypovolemia (low blood volume). It can cause dizziness, weakness, fainting, and risk of injury from falls.

Refra 2.5 Tablet 15's contains the active ingredient midodrine hydrochloride, which acts on the blood vessels via the sympathetic nervous system to correct imbalances of blood distribution. This should help relieve the symptoms you might suffer, such as dizziness, fainting, blurred vision, and weakness when sitting or standing up.

Take Refra 2.5 Tablet 15's as prescribed by your doctor. Depending on your medical condition, you are advised to take Refra 2.5 Tablet 15's for as long as your doctor prescribes it. Some people may experience Supine hypertension, Reflex bradycardia, Arrhythmias, Rash, Nausea, Vomiting, Dyspepsia, Headache, and Urinary retention. Most of these side effects of Refra 2.5 Tablet 15's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Inform your doctor if you are allergic to Refra 2.5 Tablet 15's or other medicines. If you are a pregnant woman or nursing mother, do not consume Refra 2.5 Tablet 15's without first consulting your doctor. It should not be used in children below 18 years. Midodrine is contraindicated in patients with severe organic heart disease, congestive heart failure, thyrotoxicosis, phaeochromocytoma, acute renal disease, severe renal insufficiency, urinary retention, narrow-angle glaucoma, hyperthyroidism, known hypersensitivity to any component of the product. And also, Patients with a history of CVA should be monitored closely.

Uses of Refra 2.5 Tablet 15's

Idiopathic postural hypotension or hypotension

Medicinal Benefits Mweb

Medicinal Benefits

Refra 2.5 Tablet 15's contains the active ingredient midodrine hydrochloride, which acts on the blood vessels via the sympathetic nervous system to correct imbalances of blood distribution. This should help relieve the symptoms you might suffer, such as dizziness, fainting, blurred vision, and weakness when sitting or standing up.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Side Effects of Refra 2.5 Tablet 15's

  • Supine hypertension
  • Chest pain
  • Palpitations
  • Headache
  • Blurred vision
  • Reflex bradycardia
  • Arrhythmias
  • Rash
  • Nausea
  • Vomiting
  • Dyspepsia
  • Urinary retention

Drug Warnings

If you are known to be allergic to Refra 2.5 Tablet 15's or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine. If you get pregnant during treatment with Midodrine, you must stop the treatment immediately once the pregnancy is confirmed. It should not be used in children below 18 years. Midodrine is contraindicated in patients with severe organic heart disease, congestive heart failure, thyrotoxicosis, phaeochromocytoma, acute renal disease, severe renal insufficiency, urinary retention, narrow-angle glaucoma, hyperthyroidism, known hypersensitivity to any component of the product. And also, Patients with a history of CVA should be monitored closely.

Drug-Drug Interactions

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MidodrineDihydroergotamine
Critical
MidodrineErgotamine
Severe

Drug-Drug Interactions

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MidodrineDihydroergotamine
Critical
How does the drug interact with Refra 2.5 Tablet:
Coadministration of Dihydroergotamine with Refra 2.5 Tablet can increase the risk or severity of high blood pressure.

How to manage the interaction:
Taking Dihydroergotamine with Refra 2.5 Tablet together is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any of these symptoms like headaches, abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discolouration of fingers or toes, pale or cold skin, chest pain or tightness, severe or throbbing headache, irregular heartbeat, shortness of breath, blurred vision, eye redness, confusion, or slurred speech, consult a doctor right away. Do not discontinue any medications without consulting a doctor.
MidodrineErgotamine
Severe
How does the drug interact with Refra 2.5 Tablet:
Using ergotamine together with Refra 2.5 Tablet can increase the risk or severity of high blood pressure.

How to manage the interaction:
There may be a possibility of interaction between Refra 2.5 Tablet and Ergotamine, but it can be taken if prescribed by a doctor. If you're having any of these symptoms like abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discolouration of fingers or toes, pale or cold skin, chest pain or tightness, severe or throbbing headache, irregular heartbeat, shortness of breath, blurred vision, confusion, and/or slurred speech, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
MidodrineMethysergide
Severe
How does the drug interact with Refra 2.5 Tablet:
Using methysergide maleate together with Refra 2.5 Tablet may cause significant increases in blood pressure.

How to manage the interaction:
Co-administration of Refra 2.5 Tablet with Methysergide can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discolouration of fingers or toes, pale or cold skin, chest pain or tightness, severe or throbbing headache, irregular heartbeat, shortness of breath, blurred vision, confusion, and/or slurred speech, contact a doctor immediately. Do not discontinue any medications without first consulting a doctor.
How does the drug interact with Refra 2.5 Tablet:
Taking Refra 2.5 Tablet along with linezolid could increase the risk or severity of high blood pressure.

How to manage the interaction:
Although taking linezolid with Refra 2.5 Tablet together can result in an interaction, they can be taken if a doctor has prescribed it. However, if you experience abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, severe or throbbing headache, irregular heartbeat, shortness of breath, blurred vision, confusion, and/or slurred speech, contact a doctor immediately. Do not discontinue any medication without consulting a doctor.
MidodrineDoxapram
Severe
How does the drug interact with Refra 2.5 Tablet:
Coadministration of Refra 2.5 Tablet with doxapram can increase effect of Doxapram.

How to manage the interaction:
Taking Doxapram with Refra 2.5 Tablet together can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
MidodrineIobenguane (131i)
Severe
How does the drug interact with Refra 2.5 Tablet:
Coadministration of Refra 2.5 Tablet with Iobenguane can cause a decrease in the absorption of Iobenguane resulting in a low treatment outcomes.

How to manage the interaction:
Co-administration of Refra 2.5 Tablet with Iobenguane (131i) can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • DULOXETINE
  • FLUDROCORTISONE
  • METOPROLOL

Habit Forming

No

Diet & Lifestyle Advise

  • Add foods with high vitamin B12, including eggs, fortified cereals, and nutritional yeast, to your daily diet.
  • Salty foods can increase blood pressure. Try eating canned soup, cottage cheese, olives, and pickled items.
  • Drink coffee and caffeinated tea, which may increase blood pressure by stimulating the cardiovascular system.
  • Eat small meals more frequently; large meals may drop in blood pressure as your body works harder to digest larger meals.
  • Drink more water and limit alcohol; dehydration lowers blood pressure.
  • Change body position by standing up slowly.
  • Avoid prolonged bed rest.
  • If you exercise outdoors in extreme heat, take frequent breaks.
  • Avoid spending a long time in saunas, hot tubs, and steam rooms which cause dehydration.

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