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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Synonym :

RECOMBINANT TISSUE PLASMINOGEN ACTIVATOR

Composition :

RETEPLASE-18GM

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

MISCELLANEOUS

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country of Origin: India
Other Info - RET0089

FAQs

RETEFUSE KIT INJECTION works by dissolving the blood clot that is blocking the heart's blood vessels.

RETEFUSE KIT INJECTION may increase the risk of bleeding. The sites of bleeding could be internal or external. Talk to your doctor if you have any concerns.

Heparin and RETEFUSE KIT INJECTION are incompatible. RETEFUSE KIT INJECTION should not be administered through an intravenous line containing heparin. Please consult your doctor if you have any concerns.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Consult your doctor

Limited information is available. Please consult your doctor.

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Pregnancy

Caution

Please consult your doctor if you are pregnant. Your doctor will prescribe only if the potential benefits outweigh the potential risk to the foetus.

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Breast Feeding

Caution

Please consult your doctor if you are breastfeeding. Caution should be exercised whilst administering RETEFUSE KIT INJECTION to a nursing mother.

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Driving

Consult your doctor

Limited information is available. Please consult your doctor.

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Liver

Caution

The potential risks with the therapy of RETEFUSE KIT INJECTION may be increased in patients with severe liver dysfunction and should be weighed against the anticipated benefits. Please consult your doctor.

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Kidney

Caution

The potential risks of RETEFUSE KIT INJECTION therapy may be increased in patients with severe renal dysfunction and should be weighed against the anticipated benefits. Please consult your doctor.

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Children

Caution

The efficacy and safety of RETEFUSE KIT INJECTION in children have not been established.

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Keep Refrigerated. Do not freeze.Prepaid payment required.

About RETEFUSE KIT INJECTION

RETEFUSE KIT INJECTION is a tissue plasminogen activator indicated for the treatment of acute ST-elevation myocardial infarction (STEMI) to lower the risk of heart failure and death. STEMI is a very serious type of heart attack that occurs due to blockage of the heart’s major arteries.
 
RETEFUSE KIT INJECTION contains Reteplase, which works by dissolving the blood clot that is blocking the heart blood vessel.
 
In some cases, RETEFUSE KIT INJECTION may cause side effects such as bleeding, bruising at the injection site, nausea or vomiting. You are advised to talk to your doctor if any of the side effects persist or worsen.
 
Consult your doctor if you are pregnant or breastfeeding. The efficacy and safety of RETEFUSE KIT INJECTION in children have not been established. Inform your doctor about all the medicines you are taking and your health condition to rule out any unpleasant side effects/interactions.

Uses of RETEFUSE KIT INJECTION

ST-elevation myocardial infarction (STEMI)

Medicinal Benefits Mweb

Medicinal Benefits

RETEFUSE KIT INJECTION is a tissue plasminogen activator indicated for the treatment of acute ST-elevation myocardial infarction (STEMI) to reduce the risk of heart failure and death. RETEFUSE KIT INJECTION contains Reteplase that works by dissolving the blood clot that is blocking the heart blood vessel. It may also be indicated in the treatment of a recent left bundle branch block (a delay/blockage of electrical impulses to the left side of the heart).

Directions for Use

RETEFUSE KIT INJECTION will be administered by a healthcare professional; do not self-administer.

Side Effects of RETEFUSE KIT INJECTION

  • Bleeding
  • Bruising at the injection site
  • Vomiting
  • Nausea

Drug Warnings

RETEFUSE KIT INJECTION should not be used if you are allergic to any of the components in RETEFUSE KIT INJECTION, in patients with active internal bleeding, recent stroke, recent intracranial or intraspinal surgery or serious head trauma, intracranial neoplasm (brain tumour), arteriovenous malformation, or aneurysm (ballooning and weakened area in an artery), known bleeding diathesis (tendency to bleed or bruise easily), or severe uncontrolled hypertension. RETEFUSE KIT INJECTION may cause bleeding, hypersensitivity reactions, or cholesterol embolism. Inform your doctor if you have/had recent major surgery, cerebrovascular disease, recent gastrointestinal/genitourinary bleeding, hypertension, subacute bacterial endocarditis, severe hepatic or renal disease, if you are over 75 years or if you are taking any oral anticoagulants. Consult your doctor if you are pregnant or breastfeeding. The safety and effectiveness of RETEFUSE KIT INJECTION in children have not been established.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Retefuse Kit Injection:
Taking Retefuse Kit Injection with fondaparinux can increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between fondaparinux and Retefuse Kit Injection, you can take these medicines together if prescribed by your doctor. However, if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Retefuse Kit Injection:
Taking Dabigatran etexilate with Retefuse Kit Injection can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabigatran etexilate with Retefuse Kit Injection together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Retefuse Kit Injection:
Co-administration of Ibrutinib with Retefuse Kit Injection can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Ibrutinib with Retefuse Kit Injection together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Retefuse Kit Injection:
Co-administration of Cangrelor with Retefuse Kit Injection can increase the risk of bleeding.

How to manage the interaction:
Although taking Cangrelor and Retefuse Kit Injection together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you notice any of these signs, it's important to contact a doctor right away: difficulty with bleeding, complications, bruising, feeling dizzy or lightheaded, dark or sticky stools, intense headache, weakness, or bleeding or vomiting. Do not stop using any medications without talking to a doctor.
How does the drug interact with Retefuse Kit Injection:
Taking Prasugrel with Retefuse Kit Injection can increase the risk of bleeding.

How to manage the interaction:
Co-administration of Prasugrel with Retefuse Kit Injection can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Retefuse Kit Injection:
Combining Retefuse Kit Injection with Enoxaparin can increase the risk or severity of bleeding.

How to manage the interaction:
Although there is a possible interaction between Enoxaparin and Retefuse Kit Injection, you can take these medicines together if prescribed by your doctor. If you notice any symptoms like bleeding, bruising, dizziness, or severe headache, it's important to call a doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Retefuse Kit Injection:
Coadministration of Retefuse Kit Injection and Apixaban co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Retefuse Kit Injection and Apixaban may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • HEPARIN
  • ENOXAPARIN
  • WARFARIN
  • PHENINDIONE
  • ASPIRIN
  • DIPYRIDAMOLE
  • TICLOPIDINE
  • CLOPIDOGREL

Habit Forming

No

Diet & Lifestyle Advise

  • Include vegetables, fruits and whole grains in your diet.
  • Stop smoking.
  • Be physically active every day.
  • Aim for a healthy weight.
  • Limit the consumption of alcohol.
  • Manage stress with meditation.

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