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  3. Rinodel 100 Injection 5 ml

Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Synonym :

IRINOTECAN HYDROCHLORIDE

Composition :

IRINOTECAN-20MG

Manufacturer/Marketer :

Delarc Pharmaceuticals Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Therapeutic Class

CHEMOTHERAPY

Country of origin

India

Manufacturer/Marketer address

Fliar Business Intelligence Private Limited C-32, Arya Samaj Road, Karol Bagh New Delhi, India - 250011
Other Info - RIN0246

FAQs

Rinodel 100 Injection 5 ml contains Irinotecan works by blocking an enzyme called topoisomerase I. All cells need this enzyme to divide and grow. Irinotecan blocks this enzyme so the cancer cells can't divide. As a result, Irinotecan inhibits cancer cell division and growth.

Rinodel 100 Injection 5 ml should not be used in patients with pulmonary diseases. So, inform your doctor if you have pulmonary disorders (lung problems).

While taking Rinodel 100 Injection 5 ml, make sure you visit your doctor at all the appointments to ensure that treatment works. Regular monitoring of blood and lipid tests and weight checks are required. An effective way of contraception should be used by both men and women while taking the Rinodel 100 Injection 5 ml.

The live vaccine may not work while on treatment with Rinodel 100 Injection 5 ml. Only have immunizations/vaccinations after talking to your doctor first. Also, avoid contact with people who recently had immunizations /vaccinations.

Irinotecan therapy may lead to Neutropenia (an unusually low number of neutrophil cells). Your doctor will order laboratory testing on a regular basis before and during your treatment.

You should know that this medicine may reduce fertility in both men and women. Discuss the risks of taking an irinotecan injection with your doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

Avoid alcohol consumption while on treatment with Rinodel 100 Injection 5 ml.

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Pregnancy

Unsafe

Rinodel 100 Injection 5 ml should not be used during pregnancy. So, inform your doctor if you are pregnant or suspect pregnancy. You or your partner must use a reliable form of contraception to prevent pregnancy while taking these medications.

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Breast Feeding

Unsafe

Rinodel 100 Injection 5 ml should not be used in breastfeeding. Discuss with your doctor if you have any concerns.

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Driving

Caution

Rinodel 100 Injection 5 ml can make you dizzy or impair your vision, especially in the first 24 hours after taking it. Do not drive or operate machinery until you know how this drug affects you.

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Liver

Caution

Rinodel 100 Injection 5 ml should be used with caution if you have liver disease. Inform your doctor before receiving the Rinodel 100 Injection 5 ml if you have had a liver impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

It is not recommended for use in patients on dialysis. Inform your doctor before receiving the Rinodel 100 Injection 5 ml if you have had a kidney impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Caution

Safety and effectiveness in children have not been established. Hence, use is not recommended.

About Rinodel 100 Injection 5 ml

Rinodel 100 Injection 5 ml belongs to a class of antineoplastic medications or chemotherapy drugs primarily used to manage or treat Colorectal cancer (Cancer that develops in the colon or rectal tissue). Colorectal cancer is a disease in which cells in the colon or rectum grow out of control.

Rinodel 100 Injection 5 ml contains Irinotecan works by blocking an enzyme called topoisomerase I. All cells need this enzyme to divide and grow. Irinotecan blocks this enzyme so the cancer cells can not divide. As a result, Irinotecan inhibits cancer cell division and growth.

Rinodel 100 Injection 5 ml should be administered to patients only in a hospital setting under the supervision of a physician qualified by training and experience to administer cancer chemotherapeutic agents. The most common adverse reactions are nausea, vomiting, abdominal pain, diarrhoea, constipation, anorexia (an eating disorder), Neutropenia (an unusually low number of cells called neutrophils), leukopenia (including lymphocytopenia), anaemia (not having enough healthy red blood cells), asthenia (abnormal weakness), fever, weight loss, alopecia (hair loss). You should talk to your doctor if you persistently experience these side effects.

Avoid using Rinodel 100 Injection 5 ml if you are allergic to it. Rinodel 100 Injection 5 ml can cause fetal harm when administered to a pregnant woman. It is critical not to become pregnant or get pregnant while undergoing therapy and for several months after the treatment. Using effective contraceptive methods is recommended while on treatment with Rinodel 100 Injection 5 ml. Contact your doctor immediately if you or your partner becomes pregnant while undergoing therapy. Breastfeeding is usually not advised during this treatment since it is unknown whether this medication passes into breast milk. Alcohol should be avoided during treatment with this medicine. Safety and effectiveness in children have not been established.

Uses of Rinodel 100 Injection 5 ml

Colorectal cancer

Medicinal Benefits Mweb

Medicinal Benefits

Rinodel 100 Injection 5 ml is an antineoplastic medicine or chemotherapeutic treatment used to control or treat colorectal cancer (colon or rectal cancer). Rinodel 100 Injection 5 ml contains Irinotecan acts by inhibiting an enzyme known as topoisomerase I. This enzyme is required for all cells to divide and flourish. Irinotecan inhibits this enzyme, preventing cancer cells from dividing. As a result, Irinotecan inhibits cancer cell division and growth.

Directions for Use

Rinodel 100 Injection 5 ml should be administered in a hospital setting under the supervision of a physician qualified by training and experience to administer cancer chemotherapeutic agents.

Side Effects of Rinodel 100 Injection 5 ml

  • Nausea
  • Vomiting
  • Abdominal pain
  • Diarrhoea
  • Watery eyes
  • Dizziness
  • Sweating
  • Runny nose
  • Increased saliva
  • Shrinking pupils (black circles in the middle of the eyes)
  • Constipation
  • Anorexia (an eating disorder)
  • Neutropenia (an unusually low number of cells called neutrophils)
  • Leukopenia (including lymphocytopenia)
  • Anaemia (not having enough healthy red blood cells)
  • Asthenia (abnormal weakness)
  • Fever
  • Weight loss
  • Alopecia (hair loss)

Drug Warnings

Before taking the Rinodel 100 Injection 5 ml, let your doctor know about all your medical conditions, sensitivities, and medications you are using. Also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Before and during your therapy, your doctor will prescribe laboratory testing on a regular basis. You may also suffer severe diarrhoea (known as ''late diarrhoea'') more than 24 hours after receiving Irinotecan. Your doctor would advise you to take antidiarrheal drugs at regular intervals throughout the day and night. When taking antidiarrheal drugs, always follow your doctor's instructions. During your therapy, your doctor will also inform you which foods to take and which to avoid to reduce diarrhoea. Drink plenty of fluids and strictly adhere to this diet.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Rinodel 100 Injection 5 ml:
Using Rinodel 100 Injection 5 ml together with ketoconazole can increase the risk of side effects.

How to manage the interaction:
Taking Ketoconazole with Rinodel 100 Injection 5 ml is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. However, if you experience any symptoms such as paleness, fatigue, dizziness, fainting, unexpected bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, breathing difficulty, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, consult the doctor immediately.
How does the drug interact with Rinodel 100 Injection 5 ml:
When Rinodel 100 Injection 5 ml is taken with Infliximab, it can make the body process Rinodel 100 Injection 5 ml faster. This can increase the risk or severity of developing serious infections.

How to manage the interaction:
Co-administration of Infliximab with Rinodel 100 Injection 5 ml can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you pee, it's important to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Rinodel 100 Injection 5 ml:
Co-administration of Rinodel 100 Injection 5 ml with Clozapine can increase the risk of neutropenia (low white blood count).

How to manage the interaction:
There may be a possibility of interaction between Rinodel 100 Injection 5 ml and Clozapine, but it can be taken if prescribed by a doctor. If you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, breathing difficulty, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, it is important to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Rinodel 100 Injection 5 ml:
Taking carbamazepine and Rinodel 100 Injection 5 ml may possibly reduce the effects of Rinodel 100 Injection 5 ml, which could reduce its capacity to treat cancer.

How to manage the interaction:
Although taking carbamazepine and Rinodel 100 Injection 5 ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. It is good to inform your doctor if you use any other medications.
How does the drug interact with Rinodel 100 Injection 5 ml:
Coadministration of Phenytoin and Rinodel 100 Injection 5 ml may significantly reduce the blood levels of Rinodel 100 Injection 5 ml.

How to manage the interaction:
Although there is a possible interaction between Rinodel 100 Injection 5 ml and Phenytoin, you can take these medicines together if prescribed by a doctor. Doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without talking to a doctor.
How does the drug interact with Rinodel 100 Injection 5 ml:
Taking Rifabutin and Rinodel 100 Injection 5 ml may significantly reduce the blood levels of Rinodel 100 Injection 5 ml, which may make the medication less effective.

How to manage the interaction:
Although taking Rinodel 100 Injection 5 ml and Rifabutin together can evidently cause an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms consult the doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Rinodel 100 Injection 5 ml:
Taking Ritonavir with Rinodel 100 Injection 5 ml can increase the risk of side effects.

How to manage the interaction:
Although taking Rinodel 100 Injection 5 ml and Ritonavir together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, loose stools, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, and pain or burning during urination contact a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Rinodel 100 Injection 5 ml:
Taking Tofacitinib with Rinodel 100 Injection 5 ml may increase the risk of serious infection.

How to manage the interaction:
Co-administration of Tofacitinib with Rinodel 100 Injection 5 ml can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
How does the drug interact with Rinodel 100 Injection 5 ml:
Co-administration of Gemfibrozil with Rinodel 100 Injection 5 ml can increase the risk or severity of side effects like dehydration, lung or breathing problems, or bleeding problems.

How to manage the interaction:
Although taking Gemfibrozil and Rinodel 100 Injection 5 ml together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms like diarrhea, feeling weak, blood clots, lung problems, feeling sick, throwing up, stomach pain, mouth sores, shortness of breath, looking pale, feeling tired, dizziness, fatigue, fever or chills, a sore throat, muscle pain, bleeding, bruises, losing weight, pain or burning urination consult a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Rinodel 100 Injection 5 ml:
Taking Rinodel 100 Injection 5 ml with Baricitinib can increase the risk of developing serious infections.

How to manage the interaction:
There may be a possibility of interaction between Rinodel 100 Injection 5 ml and Baricitinib, but it can be taken if prescribed by a doctor. However, consult a doctor if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • CLARITHROMYCIN
  • ERYTHROMYCIN
  • DILTIAZEM
  • ITRACONAZOLE
  • KETOCONAZOLE
  • RITONAVIR

Habit Forming

No

Special Advise

Keep all of your doctor's and laboratory appointments. Your doctor will arrange tests to assess your body's reaction to Irinotecan.

Diet & Lifestyle Advise

  • After your treatment begins, several dietary adjustments can help you control side effects.
  • Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
  • Plant-based proteins are among the greatest meals during chemotherapy or other cancer treatments. They have the highest concentrations of vitamins and minerals, such as nuts, seeds, beans and legumes.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugars.

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