apollo
0

Welcome User

Login/Sign Up

Home
Buy Medicines
Lab Tests
Doctor Consult
Circle Membership
Insurance
Blogs
Contact Us
Privacy Policy
Return & Refunds
Need Help
Terms and Conditions
  1. Home
  2. Medicine

  3. Rioteph 0.5mg Tablet 10's

Rioteph 0.5mg Tablet 10's, Pack of 10 TabletS
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Sureshvarma D , MPharma
48 Hrs returnable
Know More
COD available

Online payment accepted

rxMedicinePrescription drug

Whats That

tooltip

Composition :

RIOCIGUAT-0.50MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTI- HYPERTENSIVES

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - RIO0051

Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Sureshvarma D

Reviewed By

Sureshvarma D

MPharma

Last Updated

Jul 8, 2025 | 9:40 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Rioteph 0.5mg Tablet contains ‘Riociguat’. It works by relaxing the blood vessels in the lungs to allow blood to flow easily. Thereby, it increases the blood supply to the lungs.

Please do not stop using Rioteph 0.5mg Tablet without consulting your doctor on your own. Continue using Rioteph 0.5mg Tablet for as long as your doctor has prescribed it to treat your condition effectually. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Rioteph 0.5mg Tablet .

Rioteph 0.5mg Tablet is safe if used in the dose and duration recommended by your doctor. Take it exactly as directed, and do not skip any dose. Follow your doctor's guidelines carefully and inform your doctor if any of the side effects disturb you.

Take the missed dose as soon as possible. However, skip the missed dose and return to your regular dosing schedule if it is time for the next dose.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
bannner image

Alcohol

Caution

It is advised to limit alcohol intake since alcohol consumption with Rioteph 0.5mg Tablet may increase the risk of low blood pressure and cause adverse effects, such as dizziness, fainting, light-headedness or headache.

bannner image

Pregnancy

Caution

Consult your doctor, and there is no substantial research yet on the use of Rioteph 0.5mg Tablet in pregnant women.

bannner image

Breast Feeding

Caution

Consult your doctor, and there is no substantial research yet on the use of Rioteph 0.5mg Tablet in breastfeeding/nursing mothers.

bannner image

Driving

Caution

It is not known whether Rioteph 0.5mg Tablet alters the ability to drive. Do not drive or operate machinery if you experience any symptoms that affect your ability to concentrate and react. Seek medical attention if the symptoms persist longer.

bannner image

Liver

Caution

Please consult your doctor if you have any concerns regarding using Rioteph 0.5mg Tablet in patients with liver impairment. Your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Kidney

Caution

Please consult your doctor if you have any concerns regarding using Rioteph 0.5mg Tablet in patients with kidney impairment. Your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Children

Caution

There is limited information available on the use of Rioteph 0.5mg Tablet in children. Please consult your doctor.

Product Substitutes

Reference

  1. https://phassociation.org/patients/treatments/riociguat/
  2. https://reference.medscape.com/drug/adempas-riociguat-999863

About Rioteph 0.5mg Tablet

Rioteph 0.5mg Tablet belongs to the class of medications called soluble guanylate cyclase stimulators. It is also used to treat adults with Pulmonary Arterial Hypertension (PAH), alone or in combination with other medications. Pulmonary hypertension is a type of high blood pressure that affects the arteries in your lungs and the right side of your heart.

Rioteph 0.5mg Tablet contains ‘Riociguat’. It works by relaxing the blood vessels in the lungs. This leads to the relaxation or widening of those vessels. Relaxing and widening the blood vessels in the lungs decreases the pulmonary blood pressure to the heart and improves its function. This reduces blood pressure in the lungs, which generally results in the ability to be more active.

Rioteph 0.5mg Tablet is taken dose and duration as advised by the doctor. Rioteph 0.5mg Tablet may be prescribed alone or in combination with other blood pressure-lowering medicines depending upon your blood pressure levels. In some cases, Rioteph 0.5mg Tablet can cause side effects like headache, diarrhoea, decreased blood pressure, dizziness, vomiting, nausea, anaemia (low number of red blood cells), gastro-oesophageal reflux disease, and constipation. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Inform your doctor if you have had an allergic reaction to Rioteph 0.5mg Tablet or any ingredients in it. Let your doctor know if you have any liver disease, kidney disease, heart failure, heart valve problem or history of a heart attack. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. You must closely monitor your blood pressure if you have ever had a stroke or heart attack or currently taking other blood pressure-lowering pills. It is advised to continue taking this drug and not stop taking it suddenly without consulting your doctor. Keep your doctor informed about your health condition and all the medicines you take before taking Rioteph 0.5mg Tablet to rule out any side effects.

Uses of Rioteph 0.5mg Tablet

Pulmonary hypertension

Medicinal Benefits Mweb

Medicinal Benefits

Rioteph 0.5mg Tablet  belongs to the class of medications called soluble guanylate cyclase stimulators. Cyclic guanosine monophosphate (cyclic GMP) is a substance produced in the lungs and other parts of the body by an enzyme called guanylate cyclase in response to nitric oxide. Cyclic GMP causes the blood vessels (arteries) to relax and widen. Riociguat increases guanylate cyclase activity in two ways so that more cyclic GMP is available for the blood vessels inside the lungs. This leads to relaxation or widening of those vessels. Relaxing and widening the blood vessels in the lungs decreases the pulmonary blood pressure to the heart and improves its function. This reduces blood pressure in the lungs, which generally results in the ability to be more active.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Side Effects of Rioteph 0.5mg Tablet

  • Headache
  • Upset stomach
  • Dizziness
  • Nausea
  • Diarrhoea
  • Low blood pressure
  • Vomiting
  • Anaemia
  • Gastroesophageal reflux (known as GERD or heartburn)
  • Constipation

Drug Warnings

Inform your doctor if you have had an allergic reaction to Rioteph 0.5mg Tablet or any ingredients in it. Let your doctor know if you have any liver disease, kidney disease, heart failure, heart valve problem or history of a heart attack. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. You must closely monitor your blood pressure if you have ever had a stroke, or heart attack or currently taking other blood pressure-lowering pills. Keep your doctor informed about your health condition and all the medicines you take before taking Rioteph 0.5mg Tablet to rule out any side effects. Complete the course strictly as suggested by the doctor, even if you feel better, to avoid disease recurrence. Do not drive or operate machinery since Rioteph 0.5mg Tablet may cause side effects like dizziness and weakness, affecting your ability to concentrate and drive. Avoid consumption of alcohol with Rioteph 0.5mg Tablet as it may increase the risk of low blood pressure. Rioteph 0.5mg Tablet is not recommended in patients younger than 18 years of age.

Drug-Drug Interactions

verifiedApollotooltip
RiociguatIsosorbide dinitrate
Critical
RiociguatTheophylline
Critical

Drug-Drug Interactions

Login/Sign Up

RiociguatIsosorbide dinitrate
Critical
How does the drug interact with Rioteph 0.5mg Tablet:
Taking Rioteph 0.5mg Tablet with Isosorbide dinitrate may lead to excessively low blood pressure.

How to manage the interaction:
Taking Isosorbide dinitrate with Rioteph 0.5mg Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, priapism in males (persistent and painful erection unrelated to sexual activity). Do not discontinue any medications without consulting a doctor.
RiociguatTheophylline
Critical
How does the drug interact with Rioteph 0.5mg Tablet:
Co-administration of Theophylline with Rioteph 0.5mg Tablet can increase the risk of low blood pressure.

How to manage the interaction:
Taking Theophylline with Rioteph 0.5mg Tablet is not recommended but can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, lightheadedness, fainting, flushing (a sudden reddening of the face), headache, and nasal congestion (stuffy nose). Do not discontinue any medications without consulting a doctor.
RiociguatAvanafil
Critical
How does the drug interact with Rioteph 0.5mg Tablet:
Taking Avanafil with Rioteph 0.5mg Tablet may significantly lower blood pressure.

How to manage the interaction:
Taking Rioteph 0.5mg Tablet with Avanafil is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience dizziness, lightheadedness, fainting, flushing, headache, and nasal congestion Do not discontinue any medications without consulting a doctor.
RiociguatDipyridamole
Critical
How does the drug interact with Rioteph 0.5mg Tablet:
Taking Dipyridamole with Rioteph 0.5mg Tablet may lower blood pressure.

How to manage the interaction:
Taking Dipyridamole with Rioteph 0.5mg Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience dizziness, lightheadedness, fainting, flushing, headache, and nasal congestion Do not discontinue any medications without consulting a doctor.
RiociguatIsosorbide mononitrate
Critical
How does the drug interact with Rioteph 0.5mg Tablet:
Taking Rioteph 0.5mg Tablet with Isosorbide mononitrate can cause low blood pressure.

How to manage the interaction:
Taking Isosorbide mononitrate with Rioteph 0.5mg Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, priapism in males (persistent and painful erection unrelated to sexual activity). Do not discontinue any medications without consulting a doctor.
RiociguatTadalafil
Critical
How does the drug interact with Rioteph 0.5mg Tablet:
Taking Tadalafil with Rioteph 0.5mg Tablet may increase the risk or severity of lower the blood pressure.

How to manage the interaction:
Taking Rioteph 0.5mg Tablet with Tadalafil is generally not recommended as it can lead to an interaction, but it can be taken together if prescribed by a doctor. However, if you experience dizziness, headache, and nasal congestion consult a doctor. Do not discontinue any medications without consulting a doctor.
RiociguatAmyl nitrite
Critical
How does the drug interact with Rioteph 0.5mg Tablet:
Using Amyl Nitrite with Rioteph 0.5mg Tablet may cause excessively low blood pressure.

How to manage the interaction:
Taking Amyl nitrite with Rioteph 0.5mg Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience dizziness, lightheadedness, fainting, flushing, headache, and nasal congestion. Do not discontinue any medications without consulting a doctor.
RiociguatAminophylline
Critical
How does the drug interact with Rioteph 0.5mg Tablet:
Coadministration of Aminophylline with Rioteph 0.5mg Tablet may significantly lower your blood pressure.

How to manage the interaction:
Taking Aminophylline with Rioteph 0.5mg Tablet can cause an interaction, however, it can be taken only if a doctor has advised it. If you experience dizziness, lightheadedness, shortness of breath, fainting, flushing, headache, and nasal congestion, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RiociguatNitroprusside
Critical
How does the drug interact with Rioteph 0.5mg Tablet:
Coadministration of Nitroprusside with Rioteph 0.5mg Tablet can increase the risk of low blood pressure.

How to manage the interaction:
Taking Nitroprusside with Rioteph 0.5mg Tablet is avoided, but it can be taken when prescribed by your doctor. However, contact your doctor immediately if you experience any side effects such as dizziness, lightheadedness, headache, and nasal congestion. Do not discontinue any medications without consulting a doctor.
RiociguatSildenafil
Critical
How does the drug interact with Rioteph 0.5mg Tablet:
Co-administration of Sildenafil with Rioteph 0.5mg Tablet may lower the blood pressure.

How to manage the interaction:
Taking Rioteph 0.5mg Tablet and Sildenafil together is generally avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, flushing, headache, and nasal congestion, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

Login/Sign Up

Drug-Drug Interactions Checker List

  • SPIRONOLACTONE
  • MANNITOL
  • SOTALOL

Habit Forming

No

Special Advise

  • Keep a check on your daily blood pressure, and if you notice any fluctuations, please consult a doctor.
  • Your doctor may ask you to undergo blood and urine tests if you suffer from vomiting or dehydration.
  • If you have diabetes, using Rioteph 0.5mg Tablet may affect your blood sugar levels. Inform your doctor so that you may adjust your diabetes medication accordingly.
  • Your dietician may prescribe you a suitable exercise program and diet to manage your blood pressure.
  • Your doctor may also suggest liver function tests since the Rioteph 0.5mg Tablet may cause a change in liver enzymes.
  • may adjust your diabetes medication

Diet & Lifestyle Advise

  • Reduce sodium intake in your diet to maintain your blood pressure.
  • Eat natural and healthy foods by cutting down on high-sodium processed foods.
  • Lose those extra pounds since being obese can be a risk factor for hypertension.
  • Exercise regularly to maintain good heart health.
  • Avoid smoking and alcohol intake.
  • Chronic stress may also cause high blood pressure. Therefore, avoid stress triggers and make time to relax and do activities you enjoy.
  • Try to include heart-healthy omega-3 fatty acids-containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil and coconut oil to lower your elevated blood pressure.

Rioteph 0.5mg Tablet Substitute

Substitutes safety advice

Have a query?

Buy best Cardiology products by