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Drug-Drug Interactions
CalcitriolParicalcitol
Severe
CalcitriolDihydrotachysterol
Severe
Drug-Drug Interactions
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CalcitriolParicalcitol
Severe
How does the drug interact with Rocaltrol 0.25 mcg Capsule:
Co-administration of Paricalcitol and Rocaltrol 0.25 mcg Capsule are forms of vitamin D, and taking too much vitamin D may lead to toxic effects related to excessive calcium levels in the blood and urine.
How to manage the interaction:
Concomitant use of Paricalcitol with Rocaltrol 0.25 mcg Capsule can lead to an interaction, it can be taken if advised by a doctor. Consult the prescriber if you experience symptoms of vitamin D intoxication such as weakness, fatigue, headache, vertigo, drowsiness, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, metallic taste, muscle pain, bone pain, muscle incoordination, and low muscle tone. Do not discontinue the medication without consulting a doctor.
Co-administration of Paricalcitol and Rocaltrol 0.25 mcg Capsule are forms of vitamin D, and taking too much vitamin D may lead to toxic effects related to excessive calcium levels in the blood and urine.
How to manage the interaction:
Concomitant use of Paricalcitol with Rocaltrol 0.25 mcg Capsule can lead to an interaction, it can be taken if advised by a doctor. Consult the prescriber if you experience symptoms of vitamin D intoxication such as weakness, fatigue, headache, vertigo, drowsiness, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, metallic taste, muscle pain, bone pain, muscle incoordination, and low muscle tone. Do not discontinue the medication without consulting a doctor.
CalcitriolDihydrotachysterol
Severe
How does the drug interact with Rocaltrol 0.25 mcg Capsule:
Co-administration of Rocaltrol 0.25 mcg Capsule with Dihydrotachysterol can increase the risk of adverse effects.
How to manage the interaction:
Co-administration of Dihydrotachysterol with Rocaltrol 0.25 mcg Capsule can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, throwing up, constipation, dry mouth, strange taste in your mouth, muscle or bone pain, trouble coordinating movements, weak muscles, peeing a lot, feeling very thirsty, losing weight, eye infection, sensitivity to light, itching, or a higher body temperature - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
Co-administration of Rocaltrol 0.25 mcg Capsule with Dihydrotachysterol can increase the risk of adverse effects.
How to manage the interaction:
Co-administration of Dihydrotachysterol with Rocaltrol 0.25 mcg Capsule can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, throwing up, constipation, dry mouth, strange taste in your mouth, muscle or bone pain, trouble coordinating movements, weak muscles, peeing a lot, feeling very thirsty, losing weight, eye infection, sensitivity to light, itching, or a higher body temperature - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Rocaltrol 0.25 mcg Capsule:
Co-administration of Orlistat with Rocaltrol 0.25 mcg Capsule may reduce the levels of Rocaltrol 0.25 mcg Capsule which can lead to low treatment outcomes.
How to manage the interaction:
Although there is an interaction, Rocaltrol 0.25 mcg Capsule can be taken with Orlistat when prescribed by the doctor. Do not discontinue any medications without consulting a doctor.
Co-administration of Orlistat with Rocaltrol 0.25 mcg Capsule may reduce the levels of Rocaltrol 0.25 mcg Capsule which can lead to low treatment outcomes.
How to manage the interaction:
Although there is an interaction, Rocaltrol 0.25 mcg Capsule can be taken with Orlistat when prescribed by the doctor. Do not discontinue any medications without consulting a doctor.
CalcitriolMetolazone
Severe
How does the drug interact with Rocaltrol 0.25 mcg Capsule:
Co-administration of Metolazone with Rocaltrol 0.25 mcg Capsule can cause blood calcium levels to become too high.
How to manage the interaction:
Although there is an interaction, Rocaltrol 0.25 mcg Capsule can be taken with metolazone if prescribed by the doctor. Consult the doctor if you experience symptoms such as dizziness, drowsiness, weakness, lethargy, headache, nausea, vomiting, or seizures. Do not discontinue the medication without consulting a doctor.
Co-administration of Metolazone with Rocaltrol 0.25 mcg Capsule can cause blood calcium levels to become too high.
How to manage the interaction:
Although there is an interaction, Rocaltrol 0.25 mcg Capsule can be taken with metolazone if prescribed by the doctor. Consult the doctor if you experience symptoms such as dizziness, drowsiness, weakness, lethargy, headache, nausea, vomiting, or seizures. Do not discontinue the medication without consulting a doctor.
CalcitriolDigitoxin
Severe
How does the drug interact with Rocaltrol 0.25 mcg Capsule:
Co-administration of Rocaltrol 0.25 mcg Capsule with Digitoxin may increase the risk or severity of digitoxin toxicity and irregular heart rhythm.
How to manage the interaction:
Although there is an interaction, Rocaltrol 0.25 mcg Capsule can be taken with Digitoxin if prescribed by the doctor. Consult the prescriber if you experience symptoms that could indicate high blood calcium, such as weakness, fatigue, headache, dizziness, drowsiness, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, a metallic taste in the mouth, bone or muscle pain, incoordination, frequent urination, and weight loss. Also, seek medical attention if you experience symptoms of digitoxin toxicity, such as blurred vision, slow pulse, or irregular heartbeats. Do not discontinue the medication without consulting a doctor.
Co-administration of Rocaltrol 0.25 mcg Capsule with Digitoxin may increase the risk or severity of digitoxin toxicity and irregular heart rhythm.
How to manage the interaction:
Although there is an interaction, Rocaltrol 0.25 mcg Capsule can be taken with Digitoxin if prescribed by the doctor. Consult the prescriber if you experience symptoms that could indicate high blood calcium, such as weakness, fatigue, headache, dizziness, drowsiness, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, a metallic taste in the mouth, bone or muscle pain, incoordination, frequent urination, and weight loss. Also, seek medical attention if you experience symptoms of digitoxin toxicity, such as blurred vision, slow pulse, or irregular heartbeats. Do not discontinue the medication without consulting a doctor.
CalcitriolBurosumab
Severe
How does the drug interact with Rocaltrol 0.25 mcg Capsule:
Co-administration of Rocaltrol 0.25 mcg Capsule and Burosumab may cause increases in phosphorus and vitamin D levels in the blood, which may lead to an increased risk of kidney stones.
How to manage the interaction:
There may be a possibility of interaction between Rocaltrol 0.25 mcg Capsule and Burosumab, but it can be taken if prescribed by a doctor. If you have any of these symptoms like kidney stones, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice. Do not discontinue the medication without consulting a doctor.
Co-administration of Rocaltrol 0.25 mcg Capsule and Burosumab may cause increases in phosphorus and vitamin D levels in the blood, which may lead to an increased risk of kidney stones.
How to manage the interaction:
There may be a possibility of interaction between Rocaltrol 0.25 mcg Capsule and Burosumab, but it can be taken if prescribed by a doctor. If you have any of these symptoms like kidney stones, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice. Do not discontinue the medication without consulting a doctor.
Severe
How does the drug interact with Rocaltrol 0.25 mcg Capsule:
Co-administration of Isoniazid with Rocaltrol 0.25 mcg Capsule may decrease the effects of Rocaltrol 0.25 mcg Capsule.
How to manage the interaction:
Although there is an interaction, Rocaltrol 0.25 mcg Capsule can be taken with isoniazid if prescribed by the doctor. Do not stop using any medications without talking to a doctor. Do not discontinue the medication without consulting a doctor.
Co-administration of Isoniazid with Rocaltrol 0.25 mcg Capsule may decrease the effects of Rocaltrol 0.25 mcg Capsule.
How to manage the interaction:
Although there is an interaction, Rocaltrol 0.25 mcg Capsule can be taken with isoniazid if prescribed by the doctor. Do not stop using any medications without talking to a doctor. Do not discontinue the medication without consulting a doctor.
Severe
How does the drug interact with Rocaltrol 0.25 mcg Capsule:
Co-administration of Rocaltrol 0.25 mcg Capsule with Carbamazepine may decrease the effects of Rocaltrol 0.25 mcg Capsule.
How to manage the interaction:
Although there is an interaction, Rocaltrol 0.25 mcg Capsule can be taken with Carbamazepine if prescribed by the doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
Co-administration of Rocaltrol 0.25 mcg Capsule with Carbamazepine may decrease the effects of Rocaltrol 0.25 mcg Capsule.
How to manage the interaction:
Although there is an interaction, Rocaltrol 0.25 mcg Capsule can be taken with Carbamazepine if prescribed by the doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
CalcitriolRifapentine
Severe
How does the drug interact with Rocaltrol 0.25 mcg Capsule:
Co-administration of Rifapentine with Rocaltrol 0.25 mcg Capsule may decrease the effects of Rocaltrol 0.25 mcg Capsule.
How to manage the interaction:
Although there is an interaction, Rocaltrol 0.25 mcg Capsule can be taken with Rifapentine if prescribed by the doctor. The doctor may recommend dose adjustment or special tests to use both medicines safely. Do not discontinue the medication without consulting a doctor.
Co-administration of Rifapentine with Rocaltrol 0.25 mcg Capsule may decrease the effects of Rocaltrol 0.25 mcg Capsule.
How to manage the interaction:
Although there is an interaction, Rocaltrol 0.25 mcg Capsule can be taken with Rifapentine if prescribed by the doctor. The doctor may recommend dose adjustment or special tests to use both medicines safely. Do not discontinue the medication without consulting a doctor.
CalcitriolFosphenytoin
Severe
How does the drug interact with Rocaltrol 0.25 mcg Capsule:
Taking Rocaltrol 0.25 mcg Capsule with Fosphenytoin can reduce the levels and efficacy of Rocaltrol 0.25 mcg Capsule.
How to manage the interaction:
Taking Rocaltrol 0.25 mcg Capsule with Fosphenytoin together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any symptoms of sudden dizziness, weakness, chest pain or pressure, abnormal body movements, uncontrollable eye movements, itching, burning, or tingling sensation, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice. Do not discontinue the medication without consulting a doctor.
Taking Rocaltrol 0.25 mcg Capsule with Fosphenytoin can reduce the levels and efficacy of Rocaltrol 0.25 mcg Capsule.
How to manage the interaction:
Taking Rocaltrol 0.25 mcg Capsule with Fosphenytoin together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any symptoms of sudden dizziness, weakness, chest pain or pressure, abnormal body movements, uncontrollable eye movements, itching, burning, or tingling sensation, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice. Do not discontinue the medication without consulting a doctor.
Drug-Food Interactions
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.
Drug-Food Interactions
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Drug-Diseases Interactions
CALCITRIOL-0.25MCGOther cardiac arrhythmias
Severe
CALCITRIOL-0.25MCGDisorders of mineral metabolism
Severe
Drug-Diseases Interactions
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CALCITRIOL-0.25MCGOther cardiac arrhythmias
Severe
How does the disease interact with Rocaltrol 0.25 mcg Capsule:
Vitamin D analogues work to raise serum calcium levels and can make arrhythmias worse, especially in people on cardiac glycosides.
How to manage the interaction:
Rocaltrol 0.25 mcg Capsule increases serum calcium concentrations and may worsen arrhythmia, particularly in patients receiving cardiac glycosides. Rocaltrol 0.25 mcg Capsule should be administered cautiously in patients with arrhythmia. Monitoring of serum electrolyte concentrations and cardiac function is advised.
Vitamin D analogues work to raise serum calcium levels and can make arrhythmias worse, especially in people on cardiac glycosides.
How to manage the interaction:
Rocaltrol 0.25 mcg Capsule increases serum calcium concentrations and may worsen arrhythmia, particularly in patients receiving cardiac glycosides. Rocaltrol 0.25 mcg Capsule should be administered cautiously in patients with arrhythmia. Monitoring of serum electrolyte concentrations and cardiac function is advised.
CALCITRIOL-0.25MCGDisorders of mineral metabolism
Severe
How does the disease interact with Rocaltrol 0.25 mcg Capsule:
The use of vitamin D analogues like calciferol and ergocalciferol in individuals with hypercalcemia, malabsorption syndrome, or signs of vitamin D toxicity is not advised.
How to manage the interaction:
Serum electrolyte concentration should be corrected prior to therapy and monitored during therapy with Rocaltrol 0.25 mcg Capsule.
The use of vitamin D analogues like calciferol and ergocalciferol in individuals with hypercalcemia, malabsorption syndrome, or signs of vitamin D toxicity is not advised.
How to manage the interaction:
Serum electrolyte concentration should be corrected prior to therapy and monitored during therapy with Rocaltrol 0.25 mcg Capsule.
CALCITRIOL-0.25MCGOther disorders of kidney and ureter, not elsewhere classified
Severe
How does the disease interact with Rocaltrol 0.25 mcg Capsule:
Renal biotransformation of ergocalciferol, cholecalciferol, and calcifediol occurs during metabolic activation. Certain vitamin D analogues' therapeutic and metabolic effects may be affected by renal impairment.
How to manage the interaction:
Renal impairment can alter metabolic and therapeutic activity of certain vitamin D analogs. Alternative vitamin D analogs may be considered in patients with compromised renal function.
Renal biotransformation of ergocalciferol, cholecalciferol, and calcifediol occurs during metabolic activation. Certain vitamin D analogues' therapeutic and metabolic effects may be affected by renal impairment.
How to manage the interaction:
Renal impairment can alter metabolic and therapeutic activity of certain vitamin D analogs. Alternative vitamin D analogs may be considered in patients with compromised renal function.
CALCITRIOL-0.25MCGDependence on enabling machines and devices, not elsewhere classified
Moderate
How does the disease interact with Rocaltrol 0.25 mcg Capsule:
In order to maintain proper phosphorus levels and prevent ectopic calcification in individuals with renal impairment, vigilance should be exercised because Rocaltrol 0.25 mcg Capsule increases inorganic phosphate levels in serum.
How to manage the interaction:
Caution is advised in patients with kidney impairment to maintain adequate phosphorus levels and avoid ectopic calcification.
In order to maintain proper phosphorus levels and prevent ectopic calcification in individuals with renal impairment, vigilance should be exercised because Rocaltrol 0.25 mcg Capsule increases inorganic phosphate levels in serum.
How to manage the interaction:
Caution is advised in patients with kidney impairment to maintain adequate phosphorus levels and avoid ectopic calcification.
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