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  3. ROLAZIN TABLET

Written By ,
Reviewed By Sunny S , MBBS
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

RANOLAZINE-500MG

Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTIANGINALS

Country of origin

India

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
Other Info - ROL0016

FAQs

The active substance in ROLAZIN TABLET is Ranolazine, which reduces sodium ions flow into the heart muscle cells. This interferes with the activity of special channels on the cell surface called 'sodium-dependent calcium channels through which calcium ions normally enter the cells. This reduces the number of calcium ions that enter the cells. Calcium ions normally cause the heart muscle to contract. By reducing the flow of calcium into the cells, ROLAZIN TABLET is thought to help the heart to relax, improving blood flow to the heart muscle and relieving the symptoms of angina pectoris.

No, ROLAZIN TABLET does not stop acute attacks (sudden attacks) of angina, but ROLAZIN TABLET helps prevent a new attack.

No, alcohol should not be taken with ROLAZIN TABLET as it may lead to unwanted side effects and increase angina attacks.

Yes, smoking (tobacco) decreases the efficacy of ROLAZIN TABLET, especially when taken for angina (chest pain), so it should be avoided while taking ROLAZIN TABLET.

Yes, ROLAZIN TABLET can cause an upset stomach when taken empty stomach. So, to avoid it, ROLAZIN TABLET should be taken with a meal for best results.

Yes, ROLAZIN TABLET can cause drowsiness. If you feel excessively sleepy, please consult your doctor for better advice.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Safe if prescribed

ROLAZIN TABLET does not have any reported interaction; hence, if you experience any difficulty, discuss with your doctor.

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Pregnancy

Unsafe

ROLAZIN TABLET should not be used when pregnancy unless necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing ROLAZIN TABLET.

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Breast Feeding

Unsafe

ROLAZIN TABLET should not be used in nursing mothers. Please consult the doctor if you have any concerns regarding this.

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Driving

Safe if prescribed

ROLAZIN TABLET does not have any reported interaction; hence, in case you experience any difficulty, discuss with your doctor.

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Liver

Caution

ROLAZIN TABLET to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

ROLAZIN TABLET to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Caution

ROLAZIN TABLET is not recommended for children below the age of 18. The safety and effectiveness of ROLAZIN TABLET have not been established in children due to limited testing of this drug on children by competent authorities worldwide.

About ROLAZIN TABLET

ROLAZIN TABLET belongs to the class of anti-anginal medications. It is used alone or with other medicines to treat angina pectoris. Angina pectoris is discomfort in the chest or chest pain, which generally occurs due to coronary artery disease (CAD) when an adequate amount of oxygen and blood is not reaching the heart and its muscles. It can also be due to the blockage of the heart's arteries. It helps prevent any further attack of angina by making the heart work more efficiently, and it is used as an add-on to existing treatment in patients whose disease is not adequately controlled by other medicines for angina pectoris, such as beta-blockers or calcium antagonists, or in patients who cannot take these medicines.

The active substance in ROLAZIN TABLET is Ranolazine, which reduces sodium ions flow into the heart muscle cells. This interferes with the activity of special channels on the cell surface called 'sodium-dependent calcium channels through which calcium ions normally enter the cells. This reduces the number of calcium ions that enter the cells. Calcium ions normally cause the heart muscle to contract. By reducing the flow of calcium into the cells, ROLAZIN TABLET is thought to help the heart to relax, improving blood flow to the heart muscle and relieving the symptoms of angina pectoris.

Your doctor will tell you how to take the ROLAZIN TABLET based on your medical condition. You may sometimes experience constipation, dizziness, headache, or feeling sick. Most of these side effects of ROLAZIN TABLET do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not consume ROLAZIN TABLET if you are allergic to any component in this medicine. ROLAZIN TABLET should not be stopped even if you feel better for the best results as it prevents any future harm. If you stop taking the ROLAZIN TABLET on your own, your chest pain can come back in more severe form. If you plan to get pregnant or are pregnant or breastfeeding, please consult your doctor to avoid any unwanted harm to the baby. Some lifestyle modifications are important for best results when taking ROLAZIN TABLET like smoking cessation, decreasing alcohol intake, eating well, regular exercise, and managing stress. ROLAZIN TABLET should be taken with caution if you have any liver or kidney problems. Also, inform your doctor if you are taking other medications to avoid unwanted side effects or contraindications.

Uses of ROLAZIN TABLET

Angina Pectoris

Medicinal Benefits Mweb

Medicinal Benefits

ROLAZIN TABLET is prescribed for treating angina. ROLAZIN TABLET is an anti-anginal medication used to treat angina pectoris. It reduces sodium ions' flow into the heart muscle cells. This interferes with the activity of special channels on the cell surface called ‘sodium-dependent calcium channels’ through which calcium ions normally enter the cells. This reduces the number of calcium ions that enter the cells. Calcium ions normally cause the heart muscle to contract. By reducing the flow of calcium into the cells, ROLAZIN TABLET is thought to help the heart to relax, improving blood flow to the heart muscle and relieving the symptoms of angina pectoris.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Side Effects of ROLAZIN TABLET

  • Constipation
  • Dizziness
  • Headache
  • Feeling sick

Drug Warnings

ROLAZIN TABLET should be taken with caution in liver/kidney disease, are pregnant, plan to become pregnant, or are breastfeeding, history of heart disease. Also, grapefruit juice should be avoided while taking ROLAZIN TABLET. As a precautionary measure, junk food items from outside and stick to freshly prepared home-cooked meals for a speedy recovery. Do regular exercise to avoid the feeling of heaviness in the abdomen.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Rolazin Tablet:
When Posaconazole is taken with Rolazin Tablet, may significantly increase the blood levels and effects of Rolazin Tablet.

How to manage the interaction:
Although there is an interaction between posaconazole and Rolazin Tablet, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Rolazin Tablet:
Taking Rifabutin and Rolazin Tablet may significantly reduce the blood levels of Rolazin Tablet.

How to manage the interaction:
There may be a possibility of interaction between Rifabutin and Rolazin Tablet, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Rolazin Tablet:
When Rolazin Tablet is taken with rifampicin, it can reduce the blood levels and effects of Rolazin Tablet.

How to manage the interaction:
Although there is an interaction between Rolazin Tablet and rifampicin, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Rolazin Tablet:
When Ceritinib is taken with Rolazin Tablet, may significantly increase the blood levels and effects of Rolazin Tablet.

How to manage the interaction:
Taking Rolazin Tablet with Ceritinib together can possibly result in an interaction, but it can be taken if a doctor has advised it. In case you experience any side effects like lightheadedness, fainting, dizziness, or fast or pounding heartbeats, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Rolazin Tablet:
When Armodafinil is taken with Rolazin Tablet, the metabolism of Rolazin Tablet can be increased when combined with Armodafinil.

How to manage the interaction:
Taking Rolazin Tablet with Armodafinil is not recommended as it can result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Rolazin Tablet:
When Thioridazine is taken with Rolazin Tablet, may significantly increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Rolazin Tablet with Thioridazine together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
RanolazineEnzalutamide
Critical
How does the drug interact with Rolazin Tablet:
Taking Enzalutamide may decrease the blood levels of Rolazin Tablet, which may make Rolazin Tablet less effective.

How to manage the interaction:
Taking Enzalutamide with Rolazin Tablet is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Rolazin Tablet:
When Dexamethasone is taken with Rolazin Tablet, may significantly reduce the blood levels of Rolazin Tablet.

How to manage the interaction:
Co-administration of Rolazin Tablet and Dexamethasone can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Rolazin Tablet:
Taking Ritonavir and Rolazin Tablet may significantly increase the blood levels and effects of Rolazin Tablet.

How to manage the interaction:
Co-administration of Rolazin Tablet with Ritonavir can possibly result in an interaction, but it can be taken if a doctor has advised it. In case you experience any symptoms like feeling lightheaded, fainting, or rapid heartbeats, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Rolazin Tablet:
When Efavirenz is taken with Rolazin Tablet, it can lower the levels of Rolazin Tablet.

How to manage the interaction:
Taking Rolazin Tablet with Efavirenz is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

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RANOLAZINE-500MGGrapefruit and Grapefruit Juice
Severe

Drug-Food Interactions

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RANOLAZINE-500MGGrapefruit and Grapefruit Juice
Severe
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Grapefruit juice can increase the levels of Rolazin Tablet, and high blood levels of food can occasionally cause an irregular heart rhythm that may be serious. Grapefruit and grapefruit juice should be avoided while taking Rolazin Tablet if possible.

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • CLARITHROMYCIN
  • QUINIDINE
  • DOFETILIDE
  • SOTALOL
  • KETOCONAZOLE
  • ITRACONAZOLE

Habit Forming

No

Diet & Lifestyle Advise

  • Maintain a healthy lifestyle by exercising regularly, maintaining weight, and eating a healthy diet.
  • If you suffer from kidney or liver disease, please inform your doctor before taking the ROLAZIN TABLET.
  • Alcohol consumption along with ROLAZIN TABLET should be avoided as it may cause excessive drowsiness and increase muscle pain.
  • As a precautionary measure, junk food items from outside and stick to freshly prepared home-cooked meals for a speedy recovery.

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