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Written By Divya L , PharmaD
Reviewed By Sureshvarma D , MPharma
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Manufacturer/Marketer :

Ar-Ex Laboratories Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Therapeutic Class

ANTIBIOTIC COMBINATION

Country of origin

India

Manufacturer/Marketer address

Arex House, 21, Sitladevi Temple Road, Mahim, Mumbai, India.
Other Info - SAF0427

Author Details

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FAQs

Saf-Pid Tablet 4's consists of three antibiotic drugs, namely Azithromycin, Fluconazole, and Secnidazole. These are effective against various infection-causing microbes by inhibiting their growth. Thus Saf-Pid Tablet 4's helps to treat a variety of vaginal infections.

Saf-Pid Tablet 4's should be used with proper caution and doctor consultation if you have any liver, kidney, gastrointestinal diseases (diarrhoea and colitis, an inflammation of the colon), active infections, allergic conditions, ulcers or blisters, and urination problems.

Do not stop using Saf-Pid Tablet 4's even if you feel better until the doctor's advised course is finished. Your symptoms may improve before the infection is completely cured.

It is not advised to take any antacids containing magnesium or aluminium for up to two hours after using Saf-Pid Tablet 4's since it may interfere with the absorption of Saf-Pid Tablet 4's.

Keep Saf-Pid Tablet 4's in a cool, dry place away from direct sunlight. Dispose of unused medicine and keep it out of sight and reach from children and pets.

Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not double the dose.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

Alcohol consumption, along with Saf-Pid Tablet 4's, may cause flushing, increased heartbeat, nausea, thirst, chest pain, and low blood pressure. It is advised to avoid alcohol intake during the course with Saf-Pid Tablet 4's.

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Pregnancy

Caution

It is better to avoid Saf-Pid Tablet 4's during the first trimester of pregnancy. Please consult your doctor if you are planning to conceive or already pregnant before starting Saf-Pid Tablet 4's.

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Breast Feeding

Caution

Saf-Pid Tablet 4's should be used with caution and only under a doctor's advice if you are a lactating mother. Please seek medical advice for more information.

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Driving

Caution

Saf-Pid Tablet 4's may sometimes cause dizziness or other side effects that may affect your mental ability to drive. Hence do not drive or operate machinery if you are nor mentally alert.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before taking Saf-Pid Tablet 4's. Your doctor may adjust the dosage.

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Kidney

Caution

Caution is recommended if you have any history of kidney diseases before taking Saf-Pid Tablet 4's. Your doctor may adjust the dosage. Saf-Pid Tablet 4's is not recommended in case of severe renal impairment.

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Children

Unsafe

Saf-Pid Tablet 4's is not recommended for children below 12 years of age. Do not give this medicine to your child without medical advice.

About Saf-Pid Tablet 4's

Saf-Pid Tablet 4's belongs to the class of 'antibiotics', primarily used to treat vaginal infections, such as bacterial vaginosis (BV), candidiasis, trichomoniasis, and mixed infections with chlamydia and Neisseria. Bacterial vaginosis is caused by the change in the normal balance of vaginal bacteria. Vaginal yeast infection or Candidiasis is the infection of the vagina and tissues at the opening of the vagina (vulva). Trichomoniasis is a sexually transmitted infection caused by a parasite. Chlamydia is a sexually transmitted infection caused by bacteria. Symptoms of a vaginal infection include itching, odour and abnormal vaginal discharge.

Saf-Pid Tablet 4's comprises three medicines: Azithromycin (antibiotic), Fluconazole (antifungal), and Secnidazole (antibiotic). Azithromycin belongs to the class of 'macrolide antibiotics'. It works by inhibiting bacterial protein synthesis, which inhibits bacterial growth. Fluconazole belongs to the class of 'azole antifungal' agents. It stops the growth of fungi by causing damage and leakage to the fungal cell membrane. Secnidazole is an antibiotic that belongs to the class of 'amoebicides'. It works by stopping the growth of infection-causing bacteria.

Use Saf-Pid Tablet 4's as prescribed by the doctor. Common side effects of Saf-Pid Tablet 4's include taste changes, vomiting, headache, dizziness, stomach pain, nausea, indigestion, diarrhoea, and loss of appetite. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Inform your doctor if you are allergic to Saf-Pid Tablet 4's or any of its components. It is essential to tell your doctor if you use any other azole antifungal agents before using Saf-Pid Tablet 4's. Let your doctor know if you have any liver, kidney, gastrointestinal diseases (diarrhoea and colitis, inflammation of the colon), allergic conditions, ulcers or blisters, and urination problems. Pregnant and breastfeeding women should consult their doctor before starting Saf-Pid Tablet 4's. It is advised to avoid alcohol intake while using Saf-Pid Tablet 4's to prevent any undesirable effects.

Uses of Saf-Pid Tablet 4's

Vaginal infections, bacterial vaginosis (BV), candidiasis, and trichomoniasis. 

Medicinal Benefits Mweb

Medicinal Benefits

Saf-Pid Tablet 4's is used to treat vaginal infections, such as bacterial vaginosis (BV), candidiasis, trichomoniasis, and mixed infections with chlamydia and Neisseria. It comprises three medicines: Azithromycin, Fluconazole, and Secnidazole. Azithromycin is an antibiotic that works by inhibiting bacterial protein synthesis, which further inhibits bacterial growth. Fluconazole is an antifungal drug that stops fungi growth by causing damage and leakage to the fungal cell membrane. Secnidazole is an antibiotic works by stopping the growth of infection-causing bacteria. It effectively treats vaginal infection (bacterial vaginosis).

Directions for Use

Take Saf-Pid Tablet 4's with food as prescribed by your doctor. Swallow Saf-Pid Tablet 4's as a whole with a glass of water, do not chew, break or crush it.

Side Effects of Saf-Pid Tablet 4's

  • Taste changes
  • Vomiting
  • Headache
  • Dizziness
  • Stomach pain
  • Nausea
  • Indigestion
  • Diarrhoea
  • Loss of appetite 

Drug Warnings

Please inform your doctor if you use any prescription, non-prescription medicines, including vitamin and herbal supplements before using Saf-Pid Tablet 4's. Do not use Saf-Pid Tablet 4's if you are allergic to Saf-Pid Tablet 4's or any of its components. Let your doctor know if you have any liver, kidney, gastrointestinal diseases (diarrhea and colitis, an inflammation of the colon), allergic conditions, ulcers or blisters, and urination problems. Saf-Pid Tablet 4's is not recommended in case of severe renal impairment. It is advised to use Saf-Pid Tablet 4's under your doctor's supervision if you use other azole antifungal medicines. It is better to avoid Saf-Pid Tablet 4's during the first trimester of pregnancy. Saf-Pid Tablet 4's should be used with caution and only under a doctor's advice if you are a nursing mother. Do not drive or operate machinery if you experience dizziness or other side effects that may affect your mental ability to drive. Avoid alcohol consumption along with Saf-Pid Tablet 4's to avoid undesirable effects like flushing, increased heartbeat, nausea, thirst, chest pain, and low blood pressure. Do not take any antacids containing magnesium or aluminum for up to two hours after using Saf-Pid Tablet 4's.

Drug-Drug Interactions

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FluconazoleEliglustat
Critical
FluconazoleLomitapide
Critical

Drug-Drug Interactions

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FluconazoleEliglustat
Critical
How does the drug interact with Saf-Pid Tablet:
When Eliglustat and Saf-Pid Tablet are taken together, Saf-Pid Tablet can significantly increase the blood levels of eliglustat.

How to manage the interaction:
Taking Saf-Pid Tablet with Eliglustat together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, slow heart rate, weak pulse, or heart palpitations. Do not discontinue any medications without consulting a doctor.
FluconazoleLomitapide
Critical
How does the drug interact with Saf-Pid Tablet:
When Lomitapide is taken with Saf-Pid Tablet, may increase the blood levels of lomitapide.

How to manage the interaction:
Taking Saf-Pid Tablet with Lomitapide together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, light-colored stools, and yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
FluconazoleAstemizole
Critical
How does the drug interact with Saf-Pid Tablet:
When Astemizole is taken with Saf-Pid Tablet, the body's ability to break down Astemizole may be reduced.

How to manage the interaction:
Taking Saf-Pid Tablet with Astemizole can lead to an interaction, please consult a doctor before taking it. Do not discontinue the medications without of consulting a doctor.
FluconazoleErythromycin
Critical
How does the drug interact with Saf-Pid Tablet:
Taking Saf-Pid Tablet with Erythromycin can increase the risk of heart rhythm problems.

How to manage the interaction:
Taking Saf-Pid Tablet with Erythromycin together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
AzithromycinZiprasidone
Critical
How does the drug interact with Saf-Pid Tablet:
Co-administration of Saf-Pid Tablet with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Ziprasidone and Saf-Pid Tablet but can be taken together if prescribed by a doctor. Contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
FluconazoleDicoumarol
Severe
How does the drug interact with Saf-Pid Tablet:
Taking Saf-Pid Tablet with Dicumarol may increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction, Saf-Pid Tablet can be taken with Dicumarol if prescribed by the doctor. Consult the doctor if you experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue the medications without a doctor's advice.
FluconazoleRuxolitinib
Severe
How does the drug interact with Saf-Pid Tablet:
Co-administration of Ruxolitinib with Saf-Pid Tablet may increase the blood levels of Ruxolitinib.

How to manage the interaction:
Although there is a possible interaction, Saf-Pid Tablet can be taken with Ruxolitinib if prescribed by the doctor. Consult the doctor if you experience signs and symptoms such as paleness, tiredness, dizziness, fainting, unusual bleeding or bruising, fever, chills, sore throat, body aches, or other flu-like symptoms. Do not discontinue the medications without consulting a doctor.
FluconazoleAcetohexamide
Severe
How does the drug interact with Saf-Pid Tablet:
Co-administration of Saf-Pid Tablet with Acetohexamide may increase the blood levels and effects of Acetohexamide and more likely to experience hypoglycemia (low blood glucose levels).

How to manage the interaction:
Although taking Saf-Pid Tablet and Acetohexamide together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you notice any of these symptoms - low blood sugar, headache, dizziness, feeling tired, feeling anxious, confusion, shaking, feeling sick, feeling hungry, weakness, or a fast heartbeat - make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
FluconazoleSimeprevir
Severe
How does the drug interact with Saf-Pid Tablet:
Co-administration of Simeprevir with Saf-Pid Tablet may significantly increase the blood levels of Simeprevir.

How to manage the interaction:
Although there is a possible interaction between Saf-Pid Tablet and Simeprevir, you can take these medicines together if prescribed by a doctor. If you're having a skin rash or sensitivity to light, it's important to let a doctor know right away. Do not discontinue any medications without consulting a doctor.
FluconazoleBrigatinib
Severe
How does the drug interact with Saf-Pid Tablet:
Taking Saf-Pid Tablet with Brigatinib can raise the levels of Brigatinib in the blood, which may increase the risk of side effects.

How to manage the interaction:
Although there is a possible interaction, Saf-Pid Tablet can be taken with Brigatinib if prescribed by the doctor. Consult the prescriber if you experience paleness, fatigue, dizziness, fainting, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, or pain and burning during urination. Do not discontinue the medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • DIGOXIN
  • TRIAZOLAM
  • CYCLOSPORINE
  • TACROLIMUS
  • CARBAMAZEPINE
  • PHENYTOIN
  • RIFAMPICIN
  • RIFABUTIN
  • THEOPHYLLINE
  • ASTEMIZOLE

Habit Forming

No

Special Advise

It is advised to reach out to your doctor if the infection symptoms persist or worsen after two weeks of treatment. 

Diet & Lifestyle Advise

  • Avoid frequent douching to maintain the natural moisture in the vagina.
  • Use mild soap while taking baths and prefer warm baths.
  • Avoid harsh products on your skin.
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
  • Avoid or limit the intake of alcohol and caffeine.

Saf-Pid Tablet 4's Substitute

Substitutes safety advice
  • Fanny Kit Tablet 4's

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    30.00per tablet
  • Canforce 3 Kit Tablet 4's

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    38.70per tablet
  • Amthro SF Kit 4's

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    22.27per tablet
  • Cantras Kit Tablet 4's

    by Others

    28.13per tablet
  • Canfree 3 Kit (1+1+2 Tablet)

    by Others

    29.02per tablet
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