Safepraz Plus Capsule is a combination medication used to treat gastro-oesophageal reflux disease (GERD), indigestion, duodenal ulcers, erosive oesophagitis (acid-related damage to the lining of the oesophagus), infections caused by Helicobacter pylori when given along with an antibiotic, and Zollinger-Ellison syndrome. The stomach is usually protected from acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets eroded, which leads to complications like GERD, acidity, and peptic ulcers.

Safepraz Plus Capsule contains Pantoprazole and Cinitapride. Pantoprazole works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of stomach acid. Cinitapride increases the pressure of the inferior oesophageal sphincter, thereby preventing the back-flow of food and acid from the stomach into the mouth. Together, Safepraz Plus Capsule helps in preventing acid reflux, thereby providing relief from acidity and heartburn. 

You are advised to take Safepraz Plus Capsule for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as headache, flatulence, stomach pain, constipation, and diarrhoea. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Consult your doctor if you are pregnant or breastfeeding. Safepraz Plus Capsule may cause dizziness, so drive only if you are alert. Safepraz Plus Capsule should not be given to children as safety has not been established. Avoid consuming alcohol along with Safepraz Plus Capsule as it could lead to increased drowsiness and can elevate the production of stomach acid. Keep your doctor informed about all the medicines and your health condition to rule out any side-effects.

Safepraz Plus Capsule is a combination medicine used to treat gastro-oesophageal reflux disease (GERD), indigestion, duodenal ulcers, erosive oesophagitis (acid-related damage to the lining of the oesophagus), infections caused by Helicobacter pylori when given along with an antibiotic, and Zollinger-Ellison syndrome. Safepraz Plus Capsule is a combination of two drugs, namely: Pantoprazole and Cinitapride. Pantoprazole is a proton pump inhibitor which works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid. Cinitapride is a gastro-prokinetic agent which increases the pressure of the inferior oesophageal sphincter, thereby preventing the back-flow of food and acid from the stomach into the mouth. Together, Safepraz Plus Capsule helps in preventing acid reflux, thereby providing relief from acidity. Safepraz Plus Capsule increases gastrointestinal motility by enhancing the strength of contractions without disrupting their rhythm, thereby helps in treating indigestion.

Do not take Safepraz Plus Capsule if you are allergic to any of its contents. Inform your doctor before taking Safepraz Plus Capsule if you have severe liver or kidney problems; if you are due to have Chromogranin A test. Consult your doctor if you experience unexplained weight loss, stomach pain, indigestion, vomit food or blood, or if you pass black stools. On long-term treatment, Safepraz Plus Capsule may cause osteoporosis, hypomagnesemia (low levels of magnesium), and may reduce the absorption of vitamin B12. Consult your doctor if you are pregnant or breastfeeding. Safepraz Plus Capsule may cause dizziness, so drive only if you are alert. Safepraz Plus Capsule should not be given to children as safety has not been established. Avoid consuming alcohol along with Safepraz Plus Capsule as it could lead to increased drowsiness and can elevate the production of stomach acid. Keep your doctor informed about all the medicines and your health condition to rule out any side-effects.

• Inform your doctor before taking Safepraz Plus Capsule  if you are due to have Chromogranin A test.
• Regular monitoring of magnesium and vitamin B12 levels is advised if you are on long-term treatment with Safepraz Plus Capsule .
• Your doctor may recommend calcium and vitamin supplements if you are on long-term treatment with Safepraz Plus Capsule .