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  3. Samlet 2.5 mg Tablet 5's

Prescription drug
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS

Composition :

LETROZOLE-2.5MG

Manufacturer/Marketer :

Samarth Life Sciences Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Therapeutic Class

CHEMOTHERAPY

Country of origin

India

Manufacturer/Marketer address

Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090.
Other Info - SAM0269

Author Details

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FAQs

Samlet 2.5 mg Tablet 5's works by blocking the aromatase enzyme, which is involved in the production of estrogens. The cancer cells require estrogen for their growth, so by blocking the enzyme Samlet 2.5 mg Tablet 5's prevents the growth of cancer cells. Thereby, Samlet 2.5 mg Tablet 5's helps in slowing down or stopping the growth and/or spreading the tumours to other body parts.

Samlet 2.5 mg Tablet 5's causes dizziness and drowsiness. So, drive only if you are alert and omit driving or operating machinery if you feel dizzy or drowsy.

High blood pressure could be a side-effect of Samlet 2.5 mg Tablet 5's. Regularly monitor blood pressure levels while taking Samlet 2.5 mg Tablet 5's. Consult your doctor if you regularly notice high blood pressure levels.

Do not stop taking Samlet 2.5 mg Tablet 5's on your own. You are advised to take Samlet 2.5 mg Tablet 5's for as long as your doctor has prescribed it for you depending on your medical condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Samlet 2.5 mg Tablet 5's.

Samlet 2.5 mg Tablet 5's may cause osteoporosis (bone thinning) due to the reduction of estrogen in the body. Regular bone density tests may help you monitor osteoporosis. Contact your doctor if you observe any sign of tendon pain or swelling while taking Samlet 2.5 mg Tablet 5's.

Disclaimer

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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Samlet 2.5 mg Tablet 5's to avoid unpleasant side effects. Alcohol intake, along with Samlet 2.5 mg Tablet 5's, may cause increased drowsiness.

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Pregnancy

Unsafe

Samlet 2.5 mg Tablet 5's is pregnancy category D medicine so, should not be taken during pregnancy.

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Breast Feeding

Unsafe

Samlet 2.5 mg Tablet 5's should not be taken during breastfeeding as it passes into the breastmilk and may harm the nursing baby.

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Driving

Caution

Samlet 2.5 mg Tablet 5's may cause dizziness and drowsiness, do not drive or operate heavy machinery if you feel dizzy.

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Liver

Safe if prescribed

It is safe to take Samlet 2.5 mg Tablet 5's if prescribed. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Safe if prescribed

It is safe to take Samlet 2.5 mg Tablet 5's if prescribed. Please consult your doctor if you have kidney impairment or any concerns regarding this. No dosage adjustment is required for kidney patients with creatinine clearance greater than 10 mL/min.

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Children

Unsafe

Samlet 2.5 mg Tablet 5's should not be used by children, as the efficacy and safety have not been established.

About Samlet 2.5 mg Tablet 5's

Samlet 2.5 mg Tablet 5's belongs to the group of anti-cancer medicines called aromatase inhibitors used to treat breast cancer in women who have gone through menopause (cessation of menses periods). Breast cancer is a type of cancer that develops in breast cells stimulated by the female sex hormone known as estrogen.
 
Samlet 2.5 mg Tablet 5's contains 'Letrozole' that works by blocking the aromatase enzyme, which is involved in the production of the estrogen hormone. The cancer cells require estrogen for their growth. Hence, by blocking the aromatase enzyme, Samlet 2.5 mg Tablet 5's prevents the growth of cancer cells. Thereby Samlet 2.5 mg Tablet 5's helps in preventing or stopping the growth of spreading the tumours (cancer cells) to other body parts.

You are advised to take Samlet 2.5 mg Tablet 5's for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, Samlet 2.5 mg Tablet 5's may cause certain common side-effects such as hypercholesterolemia (increased cholesterol levels), tiredness, weakness, increased sweating, feeling unwell, pain in joints, and hot flushes (feeling of warmth). Do not be reluctant to talk with your doctor if you experience any of these side-effects persistently.
 
Avoid taking Samlet 2.5 mg Tablet 5's if you are pregnant or breastfeeding. Samlet 2.5 mg Tablet 5's may cause drowsiness and dizziness, so drive only if you are alert. Samlet 2.5 mg Tablet 5's should not be given to children as safety has not been established. Avoid consuming alcohol along with Samlet 2.5 mg Tablet 5's as it could lead to increased drowsiness and dizziness. Inform your doctor about your health condition and medications to rule out any side-effects.

Uses of Samlet 2.5 mg Tablet 5's

Breast cancer

Medicinal Benefits Mweb

Medicinal Benefits

Samlet 2.5 mg Tablet 5's belongs to the group of anti-cancer medicines called aromatase inhibitors. Samlet 2.5 mg Tablet 5's is used to treat breast cancer in women who have gone through menopause (cessation of periods). Samlet 2.5 mg Tablet 5's works by blocking the aromatase enzyme, which is involved in the production of estrogens. The cancer cells require estrogen for their growth, so by blocking the enzyme Samlet 2.5 mg Tablet 5's prevents the growth of cancer cells. Thereby, Samlet 2.5 mg Tablet 5's helps in slowing down or stopping the growth and/or spreading the tumours to other body parts.

Directions for Use

Take Samlet 2.5 mg Tablet 5's with or without food. Swallow Samlet 2.5 mg Tablet 5's as a whole with a glass of water; do not chew or break it. Take Samlet 2.5 mg Tablet 5's at the same time every day.

Side Effects of Samlet 2.5 mg Tablet 5's

  • Hypercholesterolemia (increased cholesterol levels)
  • Tiredness
  • Weakness
  • Increased sweating
  • Feeling unwell
  • Pain in joints
  • Hot flushes (feeling of warmth)

Drug Warnings

Do not take Samlet 2.5 mg Tablet 5's if you are allergic to any of its contents, if you have not yet gone through menopause (still get your periods). Talk to your doctor before taking Samlet 2.5 mg Tablet 5's if you have osteoporosis (thinning of bones), bone fractures, severe liver or kidney disease. Samlet 2.5 mg Tablet 5's may cause inflammation in tendons or tendon injury; contact your doctor if you observe any sign of tendon pain or swelling while taking Samlet 2.5 mg Tablet 5's. Avoid taking Samlet 2.5 mg Tablet 5's if you are pregnant or breastfeeding. Samlet 2.5 mg Tablet 5's may cause drowsiness and dizziness, so drive only if you are alert. Samlet 2.5 mg Tablet 5's should not be given to children as safety has not been established. Avoid consuming alcohol along with Samlet 2.5 mg Tablet 5's as it could lead to increased drowsiness and dizziness. Inform your doctor about your health condition and medications before taking Samlet 2.5 mg Tablet 5's to rule out any side-effects. 

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Samlet 2.5 mg Tablet:
Samlet 2.5 mg Tablet may have a negative effect when used with Estradiol, making it less effective in treating your disease.

How to manage the interaction:
Although taking Samlet 2.5 mg Tablet and estradiol together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Samlet 2.5 mg Tablet:
when taken together Samlet 2.5 mg Tablet's function could be blocked by estramustine, which would reduce its ability to effectively treat your illness.

How to manage the interaction:
Although taking Samlet 2.5 mg Tablet and estramustine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Samlet 2.5 mg Tablet:
When taken together ethinyl estradiol may interfere with Samlet 2.5 mg Tablet's activity and make it less effective in treating the condition.

How to manage the interaction:
Although taking Samlet 2.5 mg Tablet and ethinylestradiol together can result in an interaction, it can be taken if a doctor has prescribed it. Do not stop using any medications without a doctor's advice.
LetrozoleDiethylstilbestrol
Severe
How does the drug interact with Samlet 2.5 mg Tablet:
Co-administration of Samlet 2.5 mg Tablet may have an effect when used with Diethylstilbestrol, making it less effective in treating your disease.

How to manage the interaction:
Although taking Samlet 2.5 mg Tablet and diethylstilbestrol together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
LetrozoleConjugated Estrogens
Severe
How does the drug interact with Samlet 2.5 mg Tablet:
Coadministration of Conjugated estrogens with Samlet 2.5 mg Tablet may reduce the effect of Samlet 2.5 mg Tablet.

How to manage the interaction:
Although taking Conjugated estrogen and Samlet 2.5 mg Tablet together can result in an interaction, it can be taken together if prescribed by a doctor. Do not stop using any medications without consulting a doctor.
How does the drug interact with Samlet 2.5 mg Tablet:
Co-administration of Samlet 2.5 mg Tablet and Citalopram may raise the risk of a serious irregular heartbeat.

How to manage the interaction:
Although taking Samlet 2.5 mg Tablet and Citalopram together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, rapid heartbeat, you should consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Samlet 2.5 mg Tablet:
Coadministration of thalidomide and Samlet 2.5 mg Tablet may increase the risk of blood clots.

How to manage the interaction:
Although taking Samlet 2.5 mg Tablet and thalidomide together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience symptoms such as chest pain, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness, or swelling in an arm or leg, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Samlet 2.5 mg Tablet:
Co-administration of Desogestrel together with Samlet 2.5 mg Tablet may decrease the effects of Samlet 2.5 mg Tablet.

How to manage the interaction:
Although taking Samlet 2.5 mg Tablet and Desogestrel together can result in an interaction, it can be taken if a doctor has prescribed it. Without consulting a doctor, never stop taking any medications.
LetrozoleEstrone
Severe
How does the drug interact with Samlet 2.5 mg Tablet:
When taken together Samlet 2.5 mg Tablet's function could be blocked by estrone, which would reduce its ability to effectively treat your illness.

How to manage the interaction:
Although taking Samlet 2.5 mg Tablet and estrone together can possibly result in an interaction, it can be taken if your doctor has prescribed it. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • CITALOPRAM
  • ESCITALOPRAM
  • TAMOXIFEN

Habit Forming

No

Special Advise

  • Your doctor may advise you to regularly measure bone density before, during and after the treatment as Samlet 2.5 mg Tablet 5's may cause bone thinning due to reduction of estrogens in the body.
  • Samlet 2.5 mg Tablet 5's should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Samlet 2.5 mg Tablet 5's.

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs and spices in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep; rest well.

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