apollo
0
Written By ,
Reviewed By Hari Kumar , MBBS
48 Hrs returnable
COD available

Online payment accepted

rxMedicinePrescription drug

Whats That

tooltip

Composition :

SULFASALAZINE-500MG

Manufacturer/Marketer :

Wallace Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

GASTROINTESTINAL AGENTS

Country of origin

INDIA

Manufacturer/Marketer address

Wallace Pharmaceuticals Pvt. Ltd., 3rd Floor, Dempo Trade Centre Bldg., Patto Plaza, EDC Complex, Panaji 403001, Goa, India.
Other Info - SAZ0004

FAQs

Yes, Sazo 500 Tablet is contraindicated in patients with intestinal or urinary obstruction, patients with porphyria (liver disorders), and patients hypersensitive to sulfasalazine, its metabolites, sulfonamides, or salicylates.

Yes, Sazo 500 Tablet is said to affect fertility in males as it can cause a fall in sperm count. However, it is only affected by the time this medicine is taken.

Yes, Sazo 500 Tablet is safe to use in breastfeeding. However, please inform your doctor if the baby is premature or is at risk of jaundice as this medicine might not be advised in such cases.

Yes, Sazo 500 Tablet can affect the blood count but it is rare. There is a decrease in the number of white blood cells (infection-fighting cells). In some cases, the bone marrow might completely stop producing a specific type of white blood cell, this condition is known as agranulocytosis. It occurs within two months of starting this medicine and might be accompanied by symptoms such as fever and rash. This condition resolves within one or two weeks after this medicine is discontinued.

No, Sazo 500 Tablet is a disease-modifying anti-rheumatic drug’ (DMARD) and not a painkiller. So, if you are taking a painkiller before starting this medicine, you can continue taking it along with Sazo 500 Tablet .

No, Sazo 500 Tablet should be taken in the dose and duration as advised by the doctor. If you take it in more than the recommended dose, it might cause unpleasant side-effects. If you think your symptoms are not improving, please consult your doctor.

Sazo 500 Tablet in rare cases may cause blood disorders so your doctor may ask you to have blood count, electrolytes, urea, creatinine, and liver function tests every 3 months for the first year and every 6 months next year onwards.

If well tolerated you should take a prescribed dose of Sazo 500 Tablet while the disease remains in remission. Do not stop taking your medicine unless your doctor tells you to do so.

Sazo 500 Tablet may cause central nervous system adverse effects such as serious psychiatric problems including mania, depression, and psychosis, and these symptoms have been reported to occur only infrequently.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
bannner image

Alcohol

Unsafe

It is not recommended to consume alcohol while taking Sazo 500 Tablet to avoid unpleasant side-effects.

bannner image

Pregnancy

Caution

Sazo 500 Tablet should be recommended in pregnancy only if required. In case, if prescribed to a pregnant woman, it is advised to increase the folate supplementation after consulting your doctor.

bannner image

Breast Feeding

Caution

Sazo 500 Tablet is excreted in breastmilk and is not recommended especially if the baby is premature or is at the risk of jaundice. It might cause kernicterus (excessive levels of bilirubin in the blood) in the new-born.

bannner image

Driving

Safe if prescribed

Sazo 500 Tablet does not affect the ability to drive. However, if you feel drowsy after taking Sazo 500 Tablet , it is advised not to drive.

bannner image

Liver

Unsafe

Sazo 500 Tablet is not recommended to use in patients suffering or having a history of liver diseases. In other people, rarely it can cause hepatitis (inflammation of the liver).

bannner image

Kidney

Unsafe

Sazo 500 Tablet is not recommended to use in patients suffering or having a history of kidney diseases. In other people, rarely it can cause inflammation of the kidneys.

bannner image

Children

Safe if prescribed

Sazo 500 Tablet should be advised in children only if prescribed by a child specialist.

About Sazo 500 Tablet

Sazo 500 Tablet belongs to a class of anti-inflammatory medicines known as ‘aminosalicylates’ and ‘disease-modifying anti-rheumatic drug’ (DMARD) which treats bowel diseases (ulcerative colitis, Crohn's disease), skin-related problems (psoriasis), and chronic joint diseases (rheumatoid arthritis, ankylosing spondylitis) in the children and adults. 

Sazo 500 Tablet works as an inflammation reducer by acting locally, inhibiting the formation of a chemical known as prostaglandins which control pain and inflammation. Together it helps reducing the inflammation of the intestine, skin, and joints. 

Your doctor will advise you on how often you take your tablets based on your medical condition. In some cases, you may experience a sore throat, a fever, unexplained bruising, or ringing in your ears (tinnitus). Most of these side effects of Sazo 500 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, please reach out to your doctor.

Sazo 500 Tablet can also lower your sperm count leading to a temporary decrease in male fertility. In this case, you can speak to your doctor. Your doctor might arrange a blood test before you start taking Sazo 500 Tablet . You can continue taking Sazo 500 Tablet to prevent flares up during the pregnancy. Besides this, your doctor may prescribe additional folic acid supplements during pregnancy because Sazo 500 Tablet may reduce the level of folic acid in your body. Sazo 500 Tablet can be safely taken while you are breastfeeding unless the baby is premature or at risk of jaundice. 

Uses of Sazo 500 Tablet

Ulcerative colitis, Crohn’s disease, Rheumatoid arthritis, Ankylosing spondylitis, Psoriatic arthritis, Juvenile idiopathic arthritis

Medicinal Benefits Mweb

Medicinal Benefits

Sazo 500 Tablet works by reducing the inflammation in the colon. It inhibits the formation of a chemical, prostaglandin which controls inflammation. Together it helps in reducing the inflammation at all the sites like joints, skin, and bowel (intestines) thereby treating a wider range of joint, skin and bowel diseases including ulcerative colitis, Crohn's disease, rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, juvenile idiopathic arthritis. Sazo 500 Tablet is not a pain killer rather it is an anti-inflammatory.

Directions for Use

Sazo 500 Tablet should not be used unless prescribed by a doctor. Always take Sazo 500 Tablet exactly as your doctor told you. Your doctor will advise you on how often to take your tablets on the basis of your medical condition. Swallow Sazo 500 Tablet with a full glass of water. If required tablets can be broken in half to give a smaller dose. It should be taken with food to avoid an upset stomach. It is advised to drink plenty of water while taking Sazo 500 Tablet to prevent the formation of kidney stones.

Side Effects of Sazo 500 Tablet

  • Headache
  • Indigestion
  • Nausea
  • Watery diarrhoea

Drug Warnings

Sazo 500 Tablet treatment is generally considered to be safe during pregnancy, but its usage in pregnant mothers should be discussed with the doctor if planning for pregnancy. This medication should be avoided in breastfeeding mothers as it passes into the milk and causes jaundice and brain problems in infants less than 2 years of age. Tell your doctor if you have an allergy to any other sulpha drugs (sulfonamide antibiotic) as it may cause serious skin allergies like urticaria and stevens johnson’s syndrome. In men, an intake of Sazo 500 Tablet may lower the sperm count, which improves after stopping this medicine. Tell your doctor if you have asthma, wheezing, fever, breathing difficulties, sudden severe skin rash, unusual bleeding, sore throat, fever, unexplained bruising, or any other symptoms of infection. Use of Sazo 500 Tablet may change the colour of your urine, contact lenses, and tears to yellow/orange and even make your skin more sensitive to the sunlight. But, this is normal, harmless, and nothing to worry about. You may low folic acid in pregnancy while taking Sazo 500 Tablet so your doctor might prescribe you iron or folic acid supplements.

Drug-Drug Interactions

verifiedApollotooltip
SulfasalazineCidofovir
Critical
SulfasalazineProcaine
Severe

Drug-Drug Interactions

Login/Sign Up

SulfasalazineCidofovir
Critical
How does the drug interact with Sazo 500 Tablet:
Coadministration of Cidofovir with Sazo 500 Tablet can increase the risk or severity of kidney problems.

How to manage the interaction:
Taking Sazo 500 Tablet with Cidofovir is not recommended, but can be taken together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
SulfasalazineProcaine
Severe
How does the drug interact with Sazo 500 Tablet:
Coadministration of Sazo 500 Tablet with Procaine can increase the risk of methemoglobinemia, (a rare red blood cell condition where the oxygen-carrying capacity decreases).

How to manage the interaction:
Although taking Procaine and Sazo 500 Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
SulfasalazineTeriflunomide
Severe
How does the drug interact with Sazo 500 Tablet:
Coadministration of teriflunomide with Sazo 500 Tablet can increase the risk or severity of side effects.

How to manage the interaction:
Although taking Teriflunomide and Sazo 500 Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as paleness, fatigue, dizziness, lightheadedness, unusual bleeding or bruising, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
SulfasalazineTenofovir alafenamide
Severe
How does the drug interact with Sazo 500 Tablet:
The combined use of Sazo 500 Tablet and Tenofovir alafenamide can increase the risk or severity of of kidney problems.

How to manage the interaction:
Taking Sazo 500 Tablet and tenofovir alafenamide together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
SulfasalazineTenofovir disoproxil
Severe
How does the drug interact with Sazo 500 Tablet:
Coadministration of Sazo 500 Tablet and Tenofovir disoproxil can increase the risk of kidney problems.

How to manage the interaction:
Taking Sazo 500 Tablet and Tenofovir disoproxil together can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
SulfasalazineHuman immunoglobulin
Severe
How does the drug interact with Sazo 500 Tablet:
Coadministration of Human immunoglobulin with Sazo 500 Tablet may increase the risk or severity of kidney problems.

How to manage the interaction:
Co-administration of Human immunoglobulin with Sazo 500 Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
SulfasalazinePrilocaine
Severe
How does the drug interact with Sazo 500 Tablet:
Coadministration of Sazo 500 Tablet with Prilocaine can increase the risk of methemoglobinemia, (a rare red blood cell disorder in which oxygen carrying effectively reduces).

How to manage the interaction:
Although taking Prilocaine and Sazo 500 Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
SulfasalazineDicoumarol
Severe
How does the drug interact with Sazo 500 Tablet:
Using Dicoumarol together with Sazo 500 Tablet may increase the risk or severity of bleeding. The risk increases in patients with a history of liver or kidney disorders.

How to manage the interaction:
There may be a possibility of interaction between Sazo 500 Tablet and Dicoumarol, but it can be taken if prescribed by a doctor. However, if you experience unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness call a doctor. Do not discontinue any medications without consulting a doctor.
SulfasalazineWarfarin
Severe
How does the drug interact with Sazo 500 Tablet:
Coadministration of warfarin with Sazo 500 Tablet can increase the risk of unusual bleeding disorder.

How to manage the interaction:
Although taking Sazo 500 Tablet and warfarin together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you have unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache; and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
SulfasalazineCiclosporin
Severe
How does the drug interact with Sazo 500 Tablet:
Coadministration of Sazo 500 Tablet with ciclosporin may significantly increase the side effects on kidneys.

How to manage the interaction:
Although there is a possible interaction between Sazo 500 Tablet and ciclosporin, they can be taken together if your doctor has prescribed them. In case you experience any unusual side effects, consult a doctor. Do not stop using any medications without first talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

Login/Sign Up

Drug-Drug Interactions Checker List

  • WARFARIN
  • DIGOXIN
  • GLIMEPIRIDE
  • GLYBURIDE
  • GLIPIZIDE
  • METHENAMINE
  • AZATHIOPRINE
  • MERCAPTOPURINE
  • METHOTREXATE
  • ISONIAZID

Habit Forming

No

Special Advise

It is advised to drink plenty of water to prevent the occurrence of kidney stones or crystalloids.

Diet & Lifestyle Advise

  •  It is advised to drink plenty of water to prevent the occurrence of kidney stones.
  •  Take low fibre foods such as white rice, white pasta, bread, egg, fish, tofu, butter, etc. to avoid triggering ulcerative colitis.
  •  Exercise regularly to suppress inflammation in the body.
  •  Manage stress by doing meditation and deep breathing exercises.
  •  Eat smaller meals to avoid pain in the stomach.
  •  Avoid foods that can increase or worsen ulcerative colitis such as milk, milk products, raw fruits and vegetables, beans, spicy foods, popcorn, artificial sweeteners, nuts, seeds, and fatty foods.

Sazo 500 Tablet Substitute

Substitutes safety advice
  • Saaz Tablet 10's

    by Others

    4.73per tablet
  • Salazar Tablet 10's

    by Others

    4.73per tablet
  • Sulseas 500 Tablet 10's

    by Others

    4.73per tablet
  • Sulfalet 500 mg Tablet 10's

    by Others

    4.23per tablet
  • SZN 500 Tablet 10's

    by Others

    4.73per tablet

Have a query?

winter care Floating Button
winter care Floating Button

Recommended for a 30-day course: 6 Strips

Buy Now
Add 6 Strips