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Written By Veda Maddala , M Pharmacy
Reviewed By Sunny S , MBBS

Composition :

SELEGILINE-5MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

Oral

Return Policy :

Not Returnable

Therapeutic Class

[ANTIPARKINSON AGENTS]

Country of origin

India

Manufacturer/Marketer address

Bajaj Pharmaceuticals, 256, Sisona, Bhagwanpur Roorkee, Distt. Haridwar (Uttrakhand), India
Other Info - SE93759

Author Details

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FAQs

Selerin 5mg Tablet contains Selegiline, an antiparkinson agent that works by inhibiting the action of monoamine oxidase-B enzyme that naturally breaks down dopamine. Thereby, increases dopamine in the brain and restores its levels. Thus, improves the symptoms of Parkinson’s disease.

You recommend avoiding tyramine rich foods such as broad beans, Bovril, mature cheese, fermented soya bean products or yeast extracts as it may cause severe high blood pressure.

Selerin 5mg Tablet may cause low blood pressure in some patients, especially while standing up suddenly from a sitting or lying down position and cause symptoms such as dizziness, sweating, nausea or fainting. Hence, to avoid orthostatic hypotension, you are recommended to get up slowly after lying down or sitting.

Selerin 5mg Tablet is not recommended for glaucoma (damage of optic nerve that is essential for good vision) patients as it may increase the fluid pressure inside the eye. However, regular monitoring of pressure in the eyes is recommended while on treatment with Selerin 5mg Tablet.

You are recommended to avoid taking Selerin 5mg Tablet with escitalopram as it may lead to a severe condition called ‘serotonin syndrome’ and cause symptoms such as blurred vision, stomach cramps, diarrhoea, hallucination, extreme changes in blood pressure, confusion, excessive sweating, increased heart rate, fever, shivering or shaking, tremor, incoordination, muscle spasm or stiffness. However, please consult a doctor before taking Selerin 5mg Tablet with other medicines.

No, Selerin 5mg Tablet does not cure Parkinson’s disease. Selerin 5mg Tablet is only used to reduce the symptoms of Parkinson’s disease.

Selerin 5mg Tablet should not be used with pain killers like meperidine, tramadol, methadone, propoxyphene and cough syrups containing dextromethorphan. Using together can cause severe side effects and can worsen your present condition.

Disclaimer

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Alcohol

Safe if prescribed

Avoid consumption of alcohol with Selerin 5mg Tablet as it may increase the risk of adverse effects such as drowsiness, dizziness or difficulty in concentrating.

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Pregnancy

Consult your doctor

Selerin 5mg Tablet is a Category C pregnancy drug and is usually not recommended for pregnant women. Please consult a doctor if you are pregnant as Selerin 5mg Tablet is given to pregnant women only if the doctor thinks benefits outweigh risks.

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Breast Feeding

Consult your doctor

Selerin 5mg Tablet is not recommended for breastfeeding mothers. However, please consult a doctor before taking Selerin 5mg Tablet if you are a breastfeeding mother.

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Driving

Safe if prescribed

Selerin 5mg Tablet may cause drowsiness or dizziness and make you fall asleep suddenly. It is an offence to drive if Selerin 5mg Tablet affects you. Therefore, avoid driving if you feel drowsy or dizzy after taking Selerin 5mg Tablet.

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Liver

Consult your doctor

Take Selerin 5mg Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Consult your doctor

Take Selerin 5mg Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Safe if prescribed

Selerin 5mg Tablet is not recommended for children as the safety and efficacy were not established.

About Selerin 5mg Tablet

Selerin 5mg Tablet belongs to a class of antiparkinson drugs called monoamine oxidase-B inhibitors used in the treatment of Parkinson’s disease. Parkinson’s disease is a central nervous system disorder that affects movement. It causes stiffness, shaking, difficulty in walking, coordination and balance. In Parkinson’s patients, there is a decrease in dopamine (a chemical messenger that is important for movement control) levels as the nerve cells that produce dopamine begin to die.

Selerin 5mg Tablet contains Selegiline that works by inhibiting the action of an enzyme called monoamine oxidase-B that naturally breaks down dopamine. Thereby, increases the level of dopamine and restores its level in the brain thereby improving the symptoms of Parkinson’s disease.

Take Selerin 5mg Tablet with or without food as advised by your doctor and swallow whole with a glass of water. Do not crush, chew or break it. Your doctor will advise you how often you take Selerin 5mg Tablet based on your medical condition. Some people may experience a sore mouth, swollen gums, loss of balance, difficulty in controlling movements, headache, dizziness, nausea, sleep disorders, mouth ulcers or constipation. Most of these side effects of Selerin 5mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Selerin 5mg Tablet or any other medicines, please tell your doctor. Avoid taking Selerin 5mg Tablet if you are pregnant or breastfeeding and consult a doctor. Selerin 5mg Tablet is not recommended for children. If you are about to undergo any surgery, please inform your doctor that you are taking Selerin 5mg Tablet as it may interact with certain medicines used as a part of general anaesthesia. Avoid taking Selerin 5mg Tablet if you have stomach or duodenal ulcers, angina (chest pain), high blood pressure, major heart or blood vessel problems, hyperthyroidism (overactive thyroid gland), fast or irregular heartbeat, narrow-angle glaucoma, pheochromocytoma (tumour of the adrenal gland), prostatic adenoma (tumour of prostate gland), schizophrenia, advanced dementia (loss of memory and other thinking abilities). If you have sleep problems, anxiety, a history of stomach ulcers, kidney or liver problems, any unusual urges like excessive gambling or increased sexual behaviour, inform your doctor before taking Selerin 5mg Tablet.

Uses of Selerin 5mg Tablet

Parkinson’s disease

Medicinal Benefits Mweb

Key Benefits

Selerin 5mg Tablet is an antiparkinson agent that is used in the treatment of Parkinson’s disease. In Parkinson’s patients, the nerve cells that produce dopamine (a chemical messenger that is important for movement control) begin to die. So, there is a decrease in dopamine levels. Selerin 5mg Tablet works by inhibiting the action of the monoamine oxidase-B enzyme that naturally breaks down dopamine. Thereby, increases dopamine in the brain and restores its levels. Thus, it improves the symptoms of Parkinson’s disease. Selerin 5mg Tablet can be used alone or in combination with other medicines such as levodopa to reduce uncontrolled movements.

Directions for Use

Take Selerin 5mg Tablet as advised by the doctor. Swallow it as a whole with a glass of water. Do not crush, break or chew it.

Side Effects of Selerin 5mg Tablet

  • Sore mouth
  • Swollen gums
  • Loss of balance
  • Difficulty in controlling movements
  • Headache
  • Dizziness
  • Nausea
  • Sleep disorders
  • Mouth ulcers
  • Constipation

Drug Warnings

If you are known to be allergic to Selerin 5mg Tablet or any other medicines, please tell your doctor. Avoid taking Selerin 5mg Tablet if you are pregnant or breastfeeding and consult a doctor. Selerin 5mg Tablet is not recommended for children. If you are about to undergo any surgery, please inform your doctor that you are taking Selerin 5mg Tablet as it may interact with certain medicines used as a part of general anaesthesia. Avoid taking Selerin 5mg Tablet if you have stomach or duodenal ulcers, angina (chest pain), high blood pressure, major heart or blood vessel problems, hyperthyroidism (overactive thyroid gland), fast or irregular heartbeat, narrow-angle glaucoma, pheochromocytoma (tumour of the adrenal gland), prostatic adenoma (tumour of the prostate gland), schizophrenia, advanced dementia (loss of memory and other thinking abilities). If you have sleep problems, anxiety, a history of stomach ulcers, kidney or liver problems, unusual urges like excessive gambling or increased sexual behaviour, inform your doctor before taking Selerin 5mg Tablet.

Drug-Drug Interactions Checker List

  • RASAGILINE
  • LEVODOPA
  • DOPAMINE
  • AMANTADINE
  • ESCITALOPRAM
  • CITALOPRAM
  • FLUVOXAMINE
  • FLUOXETINE
  • SERTRALINE
  • PAROXETINE
  • PROTRIPTYLINE
  • AMITRIPTYLINE
  • VENLAFAXINE
  • DULOXETINE
  • PETHIDINE
  • TRAMADOL
  • CODEINE
  • MEPERIDINE
  • LINEZOLID
  • SUMATRIPTAN
  • ZOLMITRIPTAN
  • RIZATRIPTAN
  • DIGITALIS
  • CLONAZEPAM
  • IBUPROFEN
  • NARATRIPTAN
  • ALTRETAMINE

Habit Forming

No

Special Advise

  • Selerin 5mg Tablet may cause abnormalities in certain laboratory test results such as liver function tests and blood tests. Therefore, inform your doctor or lab technician that you are on treatment with Selerin 5mg Tablet before undergoing any tests.
  • Selerin 5mg Tablet should not be used at daily doses of more than 2.5 mg/day due to the risks associated with a change in the amount of chemical messenger in the brain called a neurotransmitter. 
  • Selerin 5mg Tablet is contraindicated for use with medicine containing meperidine, as serious reactions have been experienced in patients taking both medications together. 

Diet & Lifestyle Advise

  • Avoid intake of tyramine rich foods such as broad beans, Bovril, mature cheese, fermented soya bean products or yeast extracts.
  • Eat more fibre rich foods to ease constipation.
  • Drink plenty of water to avoid headaches due to dehydration.
  • Avoid consumption of alcohol as it may increase drowsiness.

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