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Sirotem Injection works by blocking tumour cell growth and division. Thereby, it helps treat kidney cancer.
Sirotem Injection may result in immunosuppression, leading to an increased risk of infections. Wash your hands frequently and avoid contact with sick people.
Vaccination may be less effective if taken during treatment with Sirotem Injection. Also, some vaccinations should be avoided during treatment. Therefore, do not have any vaccinations without consulting the doctor.
Fertility may be compromised during treatment with Sirotem Injection. Consult the doctor if you have any concerns.
Alcohol
Consult your doctor
It is not known if alcohol interacts with Sirotem Injection. Please consult the doctor.
Pregnancy
Caution
Sirotem Injection may cause fetal harm when administered to pregnant women. Sirotem Injection should not be used during pregnancy unless clearly necessary. Consult the doctor if you are pregnant, planning for pregnancy, or thinking you may be pregnant.
Breast Feeding
Unsafe
Avoid breastfeeding while using Sirotem Injection and for three weeks after the last dose.
Driving
Not applicable
Sirotem Injection is unlikely to affect your ability to drive.
Liver
Caution
Sirotem Injection is not recommended in patients with liver problems. Consult the doctor if you have/had liver problems.
Kidney
Caution
Please consult the doctor if you have kidney impairment or any concerns regarding this. Your doctor may monitor kidney function while on treatment with this medicine.
Children
Unsafe
Sirotem Injection is not recommended for children below 18 years as effectiveness has not been established.
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About Sirotem Injection
Sirotem Injection belongs to the group of anti-cancer medicines called kinase inhibitors used to treat advanced renal cell carcinoma (a type of cancer that begins in the kidney). It may also be used for previously treated mantle cell lymphoma (a type of cancer affecting the lymph nodes).
Sirotem Injection contains Temsirolimus, which works by blocking the action of abnormal proteins needed for cancer cells to multiply. This helps slow the growth of tumours. Thereby, it helps treat kidney cancer.
In some cases, Sirotem Injection may cause side effects such as diarrhoea, nausea, vomiting, constipation, headache, fever, and decreased appetite. Most of these side effects may not require medical attention and resolve over time. Do not be reluctant to talk with your doctor if any of these side effects persist or worsen.
Consult the doctor if you are pregnant or breastfeeding. Sirotem Injection is not recommended for children below 18 years as the effectiveness has not been established. Keep your doctor informed about your health condition and medications to rule out any side effects/interactions.
Uses of Sirotem Injection
Medicinal Benefits
Sirotem Injection belongs to the group of anti-cancer medicines called kinase inhibitors used to treat advanced renal cell carcinoma (a type of cancer that begins in the kidney). It may also be used for previously treated mantle cell lymphoma (a type of cancer affecting the lymph nodes). Sirotem Injection contains Temsirolimus, a selective inhibitor of the enzyme mTOR (mammalian target of rapamycin) that blocks tumour cell growth and division. Thereby, it helps treat kidney cancer.
Directions for Use
Side Effects of Sirotem Injection
Drug Warnings
Do not use Sirotem Injection if you are allergic to any of its components if you are allergic to sirolimus (immunosuppressant), or if you have mantle cell lymphoma or liver problems. Inform the doctor if you are allergic to or cannot use anti-histamines if you have/had a tumour in the brain or spinal cord, bruising/bleeding problems, infections, inflammation of lungs, liver or kidney problems, high cholesterol levels, diabetes, eye problems, if you are taking anticoagulants if you drink alcohol or are alcoholic if you are due to undergo any vaccination or surgery, or if you are over 65 years of age. Consult the doctor if you are pregnant or breastfeeding. Sirotem Injection is not recommended for children below 18 years as the effectiveness has not been established.
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Habit Forming
Special Advise
Females of reproductive potential and males with partners of reproductive potential must use effective contraception during treatment and for three months after the last dose.
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