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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
48 Hrs returnable
COD available

Online payment accepted

Not for online sale
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Whats That

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Composition :

ISONIAZID-100MG

Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTI- TUBERCULOSIS

Country of origin

India

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
Other Info - SOL0027

Author Details

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FAQs

SOLONEX DT 100MG TABLET contains isoniazid, an antibiotic used to treat and prevent tuberculosis. SOLONEX DT 100MG TABLET prevents bacteria from producing mycolic acids, which are required for the formation of cell walls (protective coating). Additionally, SOLONEX DT 100MG TABLET may combine with an enzyme that interferes with bacterial cell metabolism. Bacteria die as a result of the disruption in their metabolism and the lack of a cell wall. As a result, it kills Mycobacterium tuberculosis bacteria that causes tuberculosis (TB) and eliminates the infection.

It is not recommended to take SOLONEX DT 100MG TABLET with food. You are advised to take SOLONEX DT 100MG TABLET on an empty stomach at least 1 hour before a meal or 2 hours after a meal for better absorption.

You are recommended to avoid foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer as they may interact with SOLONEX DT 100MG TABLET and cause adverse effects such as sweating, headache, dizziness, light-headedness, flushing (reddening of the skin), fainting due to low blood pressure, uneven, fast or forceful heartbeat.

Yes, SOLONEX DT 100MG TABLET may cause liver problems in some patients. However, please consult your doctor if you notice symptoms such as yellowing of eyes or skin, dark urine, pale stools, weakness, loss of appetite, nausea or vomiting. Your doctor may monitor your liver function while on treatment with SOLONEX DT 100MG TABLET.

You are advised to consult a doctor before taking phenytoin with SOLONEX DT 100MG TABLET as taking these medicines together may increase the levels of phenytoin in the blood and cause toxic effects. However, if you experience dizziness, vomiting, confusion or nausea, please consult your doctor.

Please do not stop taking SOLONEX DT 100MG TABLET suddenly without consulting your doctor as it may cause withdrawal symptoms such as irritation, nervousness, difficulty in sleeping, headache or having more dreams. Therefore, take SOLONEX DT 100MG TABLET for as long as your doctor has prescribed it, and if you experience any difficulty while taking SOLONEX DT 100MG TABLET, please consult your doctor.

SOLONEX DT 100MG TABLET is not recommended for patients suffering from fits as it may increase the risk of recurring fits. Therefore, it is advised to inform your doctor if you have a history of fits before taking SOLONEX DT 100MG TABLET.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

Avoid alcohol consumption while on treatment with SOLONEX DT 100MG TABLET as it may increase the risk of liver damage. Please consult your doctor in case of any concerns.

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Pregnancy

Safe if prescribed

If you are pregnant, consult your doctor before taking SOLONEX DT 100MG TABLET. Your doctor may prescribe this medicine if only the benefits outweigh the risks.

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Breast Feeding

Safe if prescribed

SOLONEX DT 100MG TABLET is excreted in breast milk in low quantities. If you are breastfeeding, consult your doctor before taking SOLONEX DT 100MG TABLET. Your doctor may prescribe this medicine if only the benefits outweigh the risks.

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Driving

Unsafe

SOLONEX DT 100MG TABLET may cause mental health problems, fits or optic neuritis (swelling of the optic nerve that may cause vision loss) in some people. Therefore, avoid driving if you experience any of these symptoms after taking SOLONEX DT 100MG TABLET.

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Liver

Caution

Take SOLONEX DT 100MG TABLET with caution, especially if you have a history of Liver diseases/conditions. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

Take SOLONEX DT 100MG TABLET with caution, especially if you have a history of Kidney diseases/conditions. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Caution

SOLONEX DT 100MG TABLET is not recommended for children below 3 months of age. However, in children above 3 months, SOLONEX DT 100MG TABLET should be used under medical supervision.

About SOLONEX DT 100MG TABLET

SOLONEX DT 100MG TABLET belongs to the group of medicines called anti-tubercular agents primarily used to treat and prevent tuberculosis (TB). Tuberculosis is an infectious bacterial disease that mainly affects the lungs, but it can also spread to other body parts such as the kidneys, brain, spine, and bone marrow. SOLONEX DT 100MG TABLET does not work against infections caused by the virus.

SOLONEX DT 100MG TABLET contains isoniazid, an antibiotic that works by preventing bacteria from producing mycolic acids, an enzyme required for cell wall formation (protective coating). As a result of the disturbance in their metabolism, bacteria that lack a cell wall die and burst. Thus, SOLONEX DT 100MG TABLET inhibits the spread of infection by acting against the bacteria Mycobacterium tuberculosis, which causes tuberculosis.

Take SOLONEX DT 100MG TABLET as prescribed. Use SOLONEX DT 100MG TABLET for as long as your doctor has prescribed it based on your medical condition. In some cases, you may experience fever, dizziness, nausea, stomach upset, loss of appetite, constipation, tiredness, numbness, or tingling in the feet or hands as side effects of SOLONEX DT 100MG TABLET. Most of these side effects do not require medical attention and gradually resolve over time. However, if any of these side effects persist or worsen, please consult your doctor.

If you are allergic to SOLONEX DT 100MG TABLET or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, please inform your doctor before taking SOLONEX DT 100MG TABLET. SOLONEX DT 100MG TABLET may cause mental health problems, fits, or optic neuritis (swelling of the optic nerve that may cause vision loss) in some people. Therefore, avoid driving if you experience any of these symptoms after taking SOLONEX DT 100MG TABLET.  Avoid foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer while on treatment with SOLONEX DT 100MG TABLET as they might interact with this medicine. If you have fits, diabetes, HIV infection, malnutrition, kidney or liver problems, or have suffered from psychosis (mental disturbances), inform your doctor before taking SOLONEX DT 100MG TABLET.

Uses of SOLONEX DT 100MG TABLET

Tuberculosis (TB)

Medicinal Benefits Mweb

Medicinal Benefits

SOLONEX DT 100MG TABLET contains isoniazid, an antibiotic used to treat and prevent tuberculosis. SOLONEX DT 100MG TABLET prevents bacteria from producing mycolic acids, which are required for the formation of cell walls (protective coating). Additionally, SOLONEX DT 100MG TABLET may combine with an enzyme that interferes with bacterial cell metabolism. Bacteria die as a result of the disruption in their metabolism and the lack of a cell wall. As a result, it kills Mycobacterium tuberculosis bacteria that causes tuberculosis (TB) and eliminates the infection.

Directions for Use

Take SOLONEX DT 100MG TABLET on an empty stomach at least one hour before or two hours after a meal or as advised by your doctor. Do not take it with food. Tablet: Swallow it as a whole with a glass of water. Do not crush, break or chew it.Syrup: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Side Effects of SOLONEX DT 100MG TABLET

  • Fever
  • Dizziness
  • Nausea
  • Stomach upset
  • Loss of appetite
  • Constipation
  • Tiredness
  • Numbness or tingling in the feet or hands

Drug Warnings

If you are known to be allergic to SOLONEX DT 100MG TABLET, please inform your doctor. If you are pregnant or breastfeeding, please inform your doctor before taking SOLONEX DT 100MG TABLET. SOLONEX DT 100MG TABLET may cause mental health problems, fits or optic neuritis (swelling of the optic nerve that may cause vision loss) in some people. Therefore, avoid driving if you experience any of these symptoms after taking SOLONEX DT 100MG TABLET. Avoid foods and drinks containing a high level of tyramine, such as fermented foods, cheese, cured meat, soya, tuna, salmon, mackerel, wine, and beer, while taking SOLONEX DT 100MG TABLET as they might cause drug-food interaction. Avoid alcohol consumption with SOLONEX DT 100MG TABLET as it may cause liver damage. If you have fits, diabetes, HIV infection, malnutrition, kidney or liver problems or have suffered from psychosis (mental disturbances), inform your doctor before taking SOLONEX DT 100MG TABLET.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Solonex Dt 100mg Tablet:
When Solonex Dt 100mg Tablet is taken with Regorafenib, it can increase the levels of Regorafenib leading to side effects.

How to manage the interaction:
Taking Regorafenib with Solonex Dt 100mg Tablet is not recommended, it taken can be taken if prescribed by the doctor.
How does the drug interact with Solonex Dt 100mg Tablet:
When Lovastatin is taken with Solonex Dt 100mg Tablet, can increase the risk of myopathy (muscles problems), including rhabdomyolysis (a condition that causes your muscles to break down, which leads to muscle death).

How to manage the interaction:
Taking Solonex Dt 100mg Tablet with Lovastatin is not recommended but can be taken if a doctor has prescribed it.
IsoniazidLomitapide
Critical
How does the drug interact with Solonex Dt 100mg Tablet:
When Lomitapide is taken with Solonex Dt 100mg Tablet, Solonex Dt 100mg Tablet may increase the blood levels of lomitapide which leads to side effects.

How to manage the interaction:
Taking Solonex Dt 100mg Tablet with Lomitapide is not recommended but can be taken if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, exhaustion, nausea, vomiting, dark urine, light stools, and skin or eye yellowing, decreased hunger, consult the doctor.
How does the drug interact with Solonex Dt 100mg Tablet:
Co-administration of Solonex Dt 100mg Tablet may considerably enhance the blood levels of Tizanidine, which may result in side effects.

How to manage the interaction:
There may be a possibility of interaction between Tizanidine and Solonex Dt 100mg Tablet, but it can be taken if prescribed by a doctor. However, consult a doctor if you experience excessive drowsiness, dizziness, lightheadedness, fainting, and irregular heart rhythm. Do not stop taking any medications without consulting a doctor.
IsoniazidBCG vaccine
Severe
How does the drug interact with Solonex Dt 100mg Tablet:
When BCG vaccine is used with Solonex Dt 100mg Tablet, its effectiveness may be reduced.

How to manage the interaction:
Although there is a possible interaction between Solonex Dt 100mg Tablet and BCG vaccine, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Solonex Dt 100mg Tablet:
Using Phenytoin together with Solonex Dt 100mg Tablet may increase the effects of Phenytoin, which may increase the risk of side effects.

How to manage the interaction:
Although taking Phenytoin and Solonex Dt 100mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience jerky eye movements, slurred speech, loss of balance, shaking, muscle stiffness or weakness, nausea, vomiting, feeling dizzy, fainting, and slow or shallow breathing, consult a doctor immediately. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Solonex Dt 100mg Tablet:
Co-administration of Rifabutin with Solonex Dt 100mg Tablet can increase the risk of liver problems.

How to manage the interaction:
Although taking Rifabutin and Solonex Dt 100mg Tablet together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, a skin rash or itching, appetite loss, nausea, vomiting, or yellowing of the skin or the whites of your eyes, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Solonex Dt 100mg Tablet:
When Halothane is taken with Solonex Dt 100mg Tablet, can increase the side affects of liver.

How to manage the interaction:
Co-administration of Solonex Dt 100mg Tablet with Halothane can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, a skin rash or itching, appetite loss, nausea, vomiting, or yellowing of the skin or the whites of your eyes, consult a doctor right away. Do not stop using any medications without talking to a doctor.
IsoniazidHalofantrine
Severe
How does the drug interact with Solonex Dt 100mg Tablet:
Co-administration of Solonex Dt 100mg Tablet and Halofantrine together can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Solonex Dt 100mg Tablet and Halofantrine together can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Solonex Dt 100mg Tablet:
Using Solonex Dt 100mg Tablet with Teriflunomide can increase the risk and severity of the side effects of the liver.

How to manage the interaction:
Taking Solonex Dt 100mg Tablet with Teriflunomide together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have any of these symptoms, it's important to consult a doctor: Fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, nausea, vomiting, abdominal pain, dark urine, light colored stool, and/or yellowing of the skin or eyes. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • CARBAMAZEPINE
  • THEOPHYLLINE
  • PREDNISOLONE
  • PHENOBARBITAL
  • VALPROIC ACID
  • FLURAZEPAM
  • TRIAZOLAM
  • DIAZEPAM
  • WARFARIN
  • PHENINDIONE
  • PROCAINAMIDE
  • ALFENTANIL
  • MIDAZOLAM
  • HALOPERIDOL
  • CHLORPROMAZINE
  • PARACETAMOL
  • PHENYTOIN
  • KETOCONAZOLE

Habit Forming

No

Special Advise

 

  • Your doctor may advise you to get regular blood tests while taking SOLONEX DT 100MG TABLET to monitor your liver function.
  • Consult a pulmonologist or lung specialist if you have had a bad cough for 3 weeks or longer, chest pain, coughing up blood or sputum from deep inside the lungs.
  • A monthly liver function test is advisable while using SOLONEX DT 100MG TABLET.

 

Diet & Lifestyle Advise

 

  • Pineapple juice might help soothe the symptoms of cough and cold. It also has anti-inflammatory and mucolytic properties.
  • Vitamin C-rich foods such as kiwi, broccoli, and bell pepper help in improving the immune system.
  • Avoid processed and fried foods.
  • Warm ginger tea or warm soup can help in providing relief from a cough.
  • Avoid foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer.
  • Quit smoking and avoid alcohol consumption.

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