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  1. Home
  2. Medicine

  3. Solprate CR 500 mg Tablet 10's

Solprate CR 500 mg Tablet 10's, Pack of 10 TabletS
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
Know More

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Whats That

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Composition :

SODIUM VALPROATE-333MG + VALPROIC ACID-145MG

Manufacturer/Marketer :

Solvate Laboratories Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTICONVULSANT

Country of origin

India

Manufacturer/Marketer address

Solvate Laboratories Pvt.Ltd., C-57, IIIrd Floor, Vikas Marg, Preet Vihar, Delhi-110092
Other Info - SOL0178

Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Sunny S

Reviewed By

Sunny S

MBBS

Last Updated

Jul 8, 2025 | 9:32 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Solprate Cr 500Mg Tablet decreases the excessive and abnormal nerve activity in the brain. Solprate Cr 500Mg Tablet increases the amount of a chemical substance called GABA, this helps in blocking the nerve transmission across the brain and provides a calming effect. Thereby helps in controlling seizures.

Do not discontinue Solprate Cr 500Mg Tablet without consulting your doctor. To treat your condition effectually, continue taking Solprate Cr 500Mg Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Solprate Cr 500Mg Tablet; your doctor will reduce the dose gradually to avoid worsening of seizures.

Solprate Cr 500Mg Tablet may cause thrombocytopenia (low levels of platelets). This might increase the risk of bleeding and bruising. Be cautious while using sharp objects. Consult your doctor if you notice unexplained bleeding or bruising.

Solprate Cr 500Mg Tablet may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a proper diet and exercising regularly.

Solprate Cr 500Mg Tablet may increase the effect of aspirin when taken together. Please consult your doctor before taking Solprate Cr 500Mg Tablet with aspirin to avoid unpleasant side-effects. Solprate Cr 500Mg Tablet and aspirin should not be given together to children below 3 years as it could lead to liver intoxication.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Solprate Cr 500Mg Tablet as it may increase the risk of seizures.

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Pregnancy

Unsafe

Solprate Cr 500Mg Tablet belongs to pregnancy category D. Avoid taking Solprate Cr 500Mg Tablet if you are pregnant unless prescribed by a doctor, as it could lead to serious birth defects.

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Breast Feeding

Caution

Solprate Cr 500Mg Tablet may pass into breastmilk. Consult your doctor before taking Solprate Cr 500Mg Tablet if you are breastfeeding.

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Driving

Unsafe

Solprate Cr 500Mg Tablet causes dizziness, sleepiness and drowsiness. Do not drive or operate machinery unless you are alert.

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Liver

Unsafe

Solprate Cr 500Mg Tablet should not be used if you have liver problems or your family has a history of liver problems. Please consult your doctor if you have any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Solprate Cr 500Mg Tablet can be given to children if prescribed by the doctor. The dose will be adjusted by the doctor depending upon the child's body weight.

Product Substitutes

Reference

  1. https://db.cbg-meb.nl/mri/pil/nlh-0678-001.pdf
  2. https://medlineplus.gov/druginfo/meds/a682412.html
  3. https://smauk.org.uk/Valproic-acid-and-Sodium-valproate
  4. https://www.drugs.com/drug-interactions/valproic-acid,valproate-sodium.html

About Solprate Cr 500Mg Tablet

Solprate Cr 500Mg Tablet belongs to a group of medicines called 'anticonvulsants' or 'anti-epileptics' primarily used to treat epilepsy/seizures/fits. Additionally, Solprate Cr 500Mg Tablet is also used to treat mood disorders and migraine. Epilepsy is a sudden rush of electricity in the brain. In patients with seizures, the typical brain electrical pattern is disrupted by sudden bursts of electrical impulse that affect an individual's consciousness, movements or sensations.
­ 
Solprate Cr 500Mg Tablet is a combination of two drugs, namely: Sodium valproate and Valproic acid. Solprate Cr 500Mg Tablet works by decreasing the excessive and abnormal nerve activity in the brain. Thereby helps in controlling seizures. Solprate Cr 500Mg Tablet increases the amount of a chemical substance called GABA, this helps block the nerve transmission across the brain and provides a calming effect.
 
You are advised to take Solprate Cr 500Mg Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as headache, sleepiness, drowsiness, impaired coordination, apathy (lack of interest), irregular periods and weight gain. Talk to your doctor if you experience these side-effects persistently.
 
Do not take Solprate Cr 500Mg Tablet if you are pregnant, as it could cause serious congenital disabilities. If you are of child-bearing age, use effective contraception while taking Solprate Cr 500Mg Tablet. Consult your doctor before taking Solprate Cr 500Mg Tablet if you are breastfeeding. Solprate Cr 500Mg Tablet causes drowsiness and dizziness, so avoid driving unless you are alert. Avoid consuming alcohol along with Solprate Cr 500Mg Tablet as it could lead to an increased risk of seizures. Care should be taken while giving Solprate Cr 500Mg Tablet to children below 3 years as there is a higher risk of liver intoxication during the first 6 months of treatment.

Uses of Solprate Cr 500Mg Tablet

Epilepsy, Mood disorder, Migraine

Medicinal Benefits Mweb

Medicinal Benefits

Solprate Cr 500Mg Tablet is a combination of two drugs, namely: Sodium valproate and Valproic acid. Solprate Cr 500Mg Tablet is used to treat epilepsy/seizures/fits, mood disorders and to prevent migraine headaches. Solprate Cr 500Mg Tablet decreases the excessive and abnormal nerve activity in the brain, thereby controlling seizures. Solprate Cr 500Mg Tablet is used to treat certain forms of epilepsy such as petit mal epilepsy (short-term unconsciousness due to disorder in the brain), myoclonic seizures (sudden muscle contractions) and grand mal epilepsy (severe muscle contractions which lead to unconsciousness). Solprate Cr 500Mg Tablet may also be used to treat epilepsy which does not sufficiently respond to other anticonvulsant drugs, such as epilepsy which is not associated with movements and epilepsy with symptoms affecting perception and deliberate movements. Solprate Cr 500Mg Tablet is used to treat both partial seizures (affects only a part of the brain) and generalised seizures (affects the entire brain).

Directions for Use

Take Solprate Cr 500Mg Tablet with or 1hour prior food. Swallow Solprate Cr 500Mg Tablet a whole with a glass of water, do not chew, or break it.

Side Effects of Solprate Cr 500Mg Tablet

  • Headache
  • Nausea
  • Vomiting
  • Diarrhoea
  • Sleepiness
  • Drowsiness
  • Impaired coordination
  • Apathy (lack of interest)
  • Hair loss
  • Irregular periods
  • Weight gain

Drug Warnings

Do not take Solprate Cr 500Mg Tablet if you are allergic to any of its contents, if you have/ had liver problems, porphyria (blood disorder) or if you are susceptible to bleeding. Inform your doctor if you have inflammation-like diseases, bone marrow damage or kidney problems. Talk to your doctor if you experience weakness, loss of appetite, lack of interest, recurrence or worsening of seizures, prolonged bleeding or abdominal pain while taking Solprate Cr 500Mg Tablet. Consult your doctor immediately if you experience suicidal tendencies while taking Solprate Cr 500Mg Tablet. Please do not stop taking Solprate Cr 500Mg Tablet without consulting your doctor to avoid the worsening of seizures. Do not take Solprate Cr 500Mg Tablet if you are pregnant, as it could cause serious birth defects. If you are of child-bearing age, use effective contraception while taking Solprate Cr 500Mg Tablet. Consult your doctor before taking Solprate Cr 500Mg Tablet if you are breastfeeding. Solprate Cr 500Mg Tablet causes drowsiness and dizziness, so avoid driving unless you are alert. Avoid consuming alcohol along with Solprate Cr 500Mg Tablet as it could lead to increased risk of seizures. Care should be taken while giving Solprate Cr 500Mg Tablet to children below 3 years as there is a higher risk of liver intoxication during the first 6 months of treatment.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • PHENOBARBITAL
  • PHENYTOIN
  • PRIMIDONE
  • CARBAMAZEPINE
  • LAMOTRIGINE
  • FELBAMATE
  • ZIDOVUDINE
  • AMITRIPTYLINE
  • SERTRALINE
  • QUETIAPINE
  • OLANZAPINE
  • RISPERIDONE
  • LEVONORGESTREL
  • MEFLOQUINE
  • CIMETIDINE
  • IMIPENEM
  • MEROPENEM
  • ERYTHROMYCIN
  • CHOLESTYRAMINE
  • CLONAZEPAM
  • DIAZEPAM

Habit Forming

No

Special Advise

  • Regular monitoring of blood count is advised while taking Solprate Cr 500Mg Tablet as it may cause spontaneous bleeding or bruising.
  • Inform your doctor that you are taking Solprate Cr 500Mg Tablet if you are due to have any surgery or dental intervention.
  • Consult your doctor if you experience irregular periods while taking Solprate Cr 500Mg Tablet.
  • If you are of child-bearing age, use effective contraception while taking Solprate Cr 500Mg Tablet.

Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps in utilising fat instead of glucose for the generation of energy.
  • Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Exercising regularly helps in maintaining weight and improving overall health. 
  • Rest well, and get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.
  • Have a seizure response plan; this helps those around you know what to do.
  • Prepare your living area; small changes may help in reducing the risk of physical injury during a seizure.
  • Understand what triggers seizures and try reducing or avoiding them.
  • Please pay attention to overall health as it can help in reducing seizure activity.
  • Install an alarm or emergency device to get assistance during a seizure attack.

Solprate Cr 500Mg Tablet Substitute

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