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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Composition :

CERITINIB-150MG

Manufacturer/Marketer :

Novartis India Ltd

Consume Type :

Oral

Expires on or after :

Return Policy :

Not Returnable

Therapeutic Class

Other Info - SPE0179

FAQs

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About Spexib Capsule

Uses of Spexib Capsule

Medicinal Benefits Mweb

Key Benefits

Directions for Use

Side Effects of Spexib Capsule

Drug Warnings

Drug-Drug Interactions

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CeritinibLomitapide
Critical

Drug-Drug Interactions

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CeritinibLomitapide
Critical
How does the drug interact with Spexib 150 mg Capsule:
Taking lomitapide with Spexib 150 mg Capsule may significantly increase the blood levels of lomitapide.

How to manage the interaction:
Although there is a interaction between Spexib 150 mg Capsule with lomitapide, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, dark colored urine, light colored stools, and yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Spexib 150 mg Capsule:
Taking Spexib 150 mg Capsule with phenytoin may significantly reduce the blood levels and effectiveness of Spexib 150 mg Capsule.

How to manage the interaction:
Taking Phenytoin with Spexib 150 mg Capsule is not recommended as it can cause an interaction, it can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Spexib 150 mg Capsule:
Combining Spexib 150 mg Capsule with Thioridazine can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Spexib 150 mg Capsule with Thioridazine is not recommended as it can lead to an interaction; it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Spexib 150 mg Capsule:
Taking Spexib 150 mg Capsule with isavuconazole may significantly increase the blood levels of isavuconazole.

How to manage the interaction:
Taking Isavuconazole with Spexib 150 mg Capsule is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loose stools, yellow discoloration of skin and eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Spexib 150 mg Capsule:
Combining Spexib 150 mg Capsule and Simvastatin can increase the blood levels and effects of Simvastatin. This can increase the risk of side effects such as liver damage and rhabdomyolysis( involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Spexib 150 mg Capsule and Simvastatin together is not recommended as it can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark-coloured urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
CeritinibConivaptan
Critical
How does the drug interact with Spexib 150 mg Capsule:
Taking conivaptan with Spexib 150 mg Capsule can significantly increase the blood levels and effects of conivaptan.

How to manage the interaction:
Taking Spexib 150 mg Capsule with Conivaptan is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience difficulty swallowing, speaking, muscle weakness, controlling body movements, confusion, mood changes, and seizures(fits). Do not discontinue any medications without consulting a doctor.
How does the drug interact with Spexib 150 mg Capsule:
Taking Spexib 150 mg Capsule with Pimozide may increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Pimozide with Spexib 150 mg Capsule is not recommended as it can lead to an interaction; it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
CeritinibSaquinavir
Critical
How does the drug interact with Spexib 150 mg Capsule:
Taking Spexib 150 mg Capsule with Saquinavir may increase the risk of irregular heart rhythm and side effects.

How to manage the interaction:
Taking Spexib 150 mg Capsule with Saquinavir is not recommended as it can lead to an interaction; it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Spexib 150 mg Capsule:
Co-administration of Spexib 150 mg Capsule and Silodosin together can increase the effect of Silodosin and increase the risk for side effects.

How to manage the interaction:
Taking Silodosin and Spexib 150 mg Capsule together is not recommended as it can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, or heart palpitation. Do not discontinue any medications without consulting a doctor.
CeritinibVenetoclax
Critical
How does the drug interact with Spexib 150 mg Capsule:
Taking Spexib 150 mg Capsule with Venetoclax may increase the risk of side effects.

How to manage the interaction:
Taking Spexib 150 mg Capsule with Venetoclax is not recommended as it can lead to an interaction; it can be taken if advised by your doctor. However, if you experience any symptoms like nausea; vomiting; diarrhea; weakness; and pain while urinating, consult the doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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