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  3. Spironot-F Tablet 10's

Spironot-F Tablet 10's, Pack of 10 TabletS
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
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Composition :

FUROSEMIDE-20MG + SPIRONOLACTONE-50MG

Manufacturer/Marketer :

Care Formulations Lab

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Spironot-F Tablet

Spironot-F Tablet belongs to a class of medicine called 'diuretics' (water pills) which helps to remove excess water from the body. Besides this, it also maintains the level of potassium in the bloodstream and prevents hypertension (high blood pressure due to oedema (fluid retention). Oedema or fluid overload is associated with pulmonary hypertension (high blood pressure in the lung) or heart failure (irregular heart pumping). Leg swelling is the main characteristic of oedema, which may be accompanied by shortness of breath, chest pain (angina), abnormal heart rhythms (arrhythmia) and swelling in other areas of the hands or abdomen.

It is a short-acting diuretic prescribed for the treatment of resistant oedema (fluid overload) associated with pulmonary hypertension (high blood pressure in the lungs), heart failure and hepatic cirrhosis (chronic liver damage). Spironot-F Tablet works by increasing the amount of urine that is passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Thus, it helps to lower high blood pressure, reducing the chances of heart attack, stroke or angina (chest pain) in future.

You can take Spironot-F Tablet with food or without food. It should be swallowed whole with a glass of water. Do not chew, crush, or break it. Your doctor will advise you how often you take Spironot-F Tablet based on your medical condition. Sometimes, you may experience low blood pressure (hypotension), dehydration, electrolyte disturbances (potassium and sodium), headache, nausea, or dizziness. Most of these side effects of Spironot-F Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking Spironot-F Tablet  of your own as doing so may raise your blood pressure, thereby increasing the risk of getting heart diseases and stroke. Inform your doctor if you are suffering from any kidney, liver or heart disease. If you are pregnant or breastfeeding, please tell your doctor so that the dosage of Spironot-F Tablet can be prescribed accordingly. Please tell your doctor if you are taking any other medicines or are allergic to Spironot-F Tablet . Reducing the amount of table salt (sodium chloride) in your food often relieves the swelling of the body.

Uses of Spironot-F Tablet

Oedema (fluid overload), Hypertension (high blood pressure).

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

When you take Spironot-F Tablet , it helps in losing out excess fluids from the body by increasing the production of urine. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Thus, it helps to lower high blood pressure, reducing the chances of heart attack or stroke. In addition, this relieves oedema and helps you carry out your daily activities more efficiently.

Storage

Keep Spironot-F Tablet out of the sight and reach of children.

Drug Warnings

Spironot-F Tablet should not be given to the people allergic to Spironot-F Tablet , have low blood pressure (less than 90 mm of Hg), have had a heart attack, kidney disease (with creatinine clearance less than 30 mL/min), liver disease, pregnant women, or planning to get pregnant and breastfeeding women. Besides this, it is contraindicated in low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart), and aortic stenosis (heart valve problem). Spironot-F Tablet can pass into breast milk, but its effect on the baby is not known, so it is better to tell your doctor if you are taking Spironot-F Tablet and breastfeeding. Spironot-F Tablet may cause vocal changes so special attention must be given to the patients using Spironot-F Tablet and whose voice is significant for their work (like actors, singers, or teachers). Hypovolaemia or dehydration with electrolyte and acid-base disturbances must be corrected before using Spironot-F Tablet .

Drug-Drug Interactions

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SpironolactoneEplerenone
Critical
SpironolactoneAmiloride
Critical

Drug-Drug Interactions

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SpironolactoneEplerenone
Critical
How does the drug interact with Spironot-F Tablet:
Combining Eplerenone with Spiranolactone may significantly increase potassium levels in the blood which can lead to kidney issues and irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Spironot-F Tablet and eplerenone, it is not recommended as it can lead to an interaction. You can take these medicines if prescribed by a doctor. Consult a doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or an irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
SpironolactoneAmiloride
Critical
How does the drug interact with Spironot-F Tablet:
Coadministration of Amiloride with Spironot-F Tablet may increase potassium levels in the blood.

How to manage the interaction:
Taking Amiloride with Spironot-F Tablet is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop taking any medication without doctor's advice.
FurosemideZiprasidone
Critical
How does the drug interact with Spironot-F Tablet:
Taking Ziprasidone with Spironot-F Tablet can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Ziprasidone with Spironot-F Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, weakness, tiredness, drowsiness, confusion, muscle pain, cramps, dizziness, nausea, or vomiting. Do not discontinue any medications without consulting a doctor.
SpironolactoneFosinopril
Severe
How does the drug interact with Spironot-F Tablet:
Using fosinopril together with Spironot-F Tablet may cause hyperkalemia (increase the levels of potassium in your blood).

How to manage the interaction:
Taking Fosinopril with Spironot-F Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feeling of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop taking any medication without doctor's advise.
SpironolactoneLithium
Severe
How does the drug interact with Spironot-F Tablet:
Taking lithium and Spironot-F Tablet may increase blood levels of lithium.

How to manage the interaction:
Although taking Spironot-F Tablet and lithium together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as loose stools, vomiting, drowsiness, shaking, thirst, lack of coordination, or muscle weakness. Do not stop using any medications without consulting doctor.
SpironolactoneCandesartan
Severe
How does the drug interact with Spironot-F Tablet:
Taking Spironot-F Tablet with candesartan may increase potassium levels in the blood.

How to manage the interaction:
Although taking Spironot-F Tablet and candesartan together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without consulting doctor.
SpironolactoneEdoxaban
Severe
How does the drug interact with Spironot-F Tablet:
Taking Spironot-F Tablet and Edoxaban may increase the blood levels of edoxaban. This can increase the risk of bleeding complications.

How to manage the interaction:
Although taking Spironot-F Tablet and edoxaban together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience any unusual bleeding or bruising, or have other signs and symptoms of bleeding such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop using any medications without consulting doctor.
SpironolactoneCaptopril
Severe
How does the drug interact with Spironot-F Tablet:
Combining Spironot-F Tablet with Captopril may significantly increase potassium levels in the blood which can lead to kidney issues and irregular heart rhythm.

How to manage the interaction:
Taking Captopril with Spironot-F Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop taking any medication without doctor's advise.
SpironolactonePotassium chloride
Severe
How does the drug interact with Spironot-F Tablet:
Taking Spironot-F Tablet with Potassium chloride may increase potassium levels in the blood which can lead to kidney problems and abnormal heart rhythm.

How to manage the interaction:
Taking Potassium chloride with Spironot-F Tablet can possibly result in an interaction, it can be taken if a doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feeling of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop taking any medication without doctor's advise.
SpironolactoneValsartan
Severe
How does the drug interact with Spironot-F Tablet:
Using Spironot-F Tablet together with valsartan may increase potassium levels in the blood.

How to manage the interaction:
Although taking Spironot-F Tablet and valsartan together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor immediately if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Consume antioxidant-rich food. Blueberries, cherries, tomatoes, squash, and bell peppers are high in antioxidants.
  • Eat natural diuretic foods. Asparagus, beets, green beans, grapes, onion, leafy greens, pineapple, leeks, pumpkin, and garlic are all-natural diuretic foods.
  • Use healthy cooking oils like soybean, olive, canola, and coconut oil.
  • You should avoid refined foods such as white bread, spaghetti, sugar, and red meat.
  • Reduce or eliminate Trans fatty acids, which are found in commercially baked items such as cookies, cakes, crackers, French fries, onion rings, doughnuts, and processed foods.
  • Avoid consumption of too much salt or salty food.
  • Keep your weight under control with a BMI of 19.5-24.9.
  • Regular physical activity or exercise like walking improves your blood flow.
  • When possible, elevate your legs or the swollen area on a chair or pillows.
  • Avoid standing or sitting for extended periods of time.
  • Avoid chronic stress as it can raise your blood pressure.
  • Spend time with your loved ones to cope with stress and practice mindfulness techniques.
  • Quitting smoking and alcohol consumption is the best strategy to lower the risk of many health complications.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Sunny S

Reviewed By

Sunny S

MBBS

Last Updated

Jul 8, 2025 | 9:29 AM IST

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

It is a medical term for fluid retention or overload. Due to oedema, the legs, hands and other body parts start swelling increasing blood pressure. If it does not subside, please consult your doctor immediately.

No, you are advised to inform your doctor and monitor your blood pressure for at least two weeks before stopping the medicine. Depending upon your current blood pressure readings, there is a possibility your doctor may lower your medicine dosage and not recommend to discontinue it.

A good rule is to drink enough fluid so that you're not thirsty for long periods.

The main side effect of Spironot-F Tablet is peeing more often than normal. Most people need to pee about 30 minutes after taking Spironot-F Tablet , and again within a few hours. Do not take Spironot-F Tablet before going to bed or you may have to wake in the night to go for the urination frequently.

You should closely monitor your blood pressure, renal function and electrolytes within 4-6 weeks of commencing therapy. Besides this, frequent checks of the potassium level are required in patients with kidney failure and with creatinine clearance below 60 ml/min per.

Loop-acting diuretics, Potassium-sparing diuretics and Thiazide diuretics are three types of diuretics available for the treatment of oedema (fluid overload).

Yes, anything that increases the production of urine is known as 'Diuretic'. Green tea contains a little amount of caffeine and has a diuretic effect that increases the volume of urine formation. Drinking too much green tea increases your urge to urinate.

If your leg (foot, ankle) or any other body's part swelling, you need to visit any physician or cardiologist who could perform an ultrasound examination of your leg veins and an ultrasound of your heart (echocardiogram-ECG).

Drug-Drug Interactions Checker List

  • LITHIUM
  • RISPERIDONE
  • LEVOTHYROXINE SODIUM
  • ASPIRIN
  • IBUPROFEN
  • SILDENAFIL
  • METOPROLOL
  • RAMIPRIL
  • HYDROCHLOROTHIAZIDE
  • ATORVASTATIN
  • CARBAMAZEPINE
  • PHENOBARBITAL

Special Advise

  • Treatment with Spironot-F Tablet requires regular monitoring of serum potassium, sodium, and creatinine level.

Disease/Condition Glossary

Oedema: Oedema, also known as fluid overload, occurs due to the build-up of fluid in spaces between the cells. Oedema can result from a variety of factors. Some oedema reasons are caused by your lifestyle, while an underlying medical problem causes others. Shortness of breath, chest pain (angina), abnormal heart rhythms (arrhythmia), and swelling in hands or abdominal areas are the symptoms of oedema.

Hypertension: It is a chronic condition when blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Blood pressure is the measurement of the force that our heart uses to pump blood to all parts of the body. Raised blood pressure can cause chest pain (angina) and heart attack (when blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor or sphygmomanometer. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is the pressure when your heart is at the resting stage between heartbeats. If your blood pressure is 140/90 mm of Hg, it means the systolic pressure is 140 mm of Hg and diastolic pressure is 90 mm of Hg. Ideal blood pressure is around 120/80 mm of Hg.

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