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Synmega 250mg/125mg Tablet is used to treat bacterial infections. It contains Ampicillin and Sulbactam. Ampicillin reduces the infection by inhibiting bacterial growth. It disrupts the formation of the cell wall (outer layer), which is essential for bacteria's survival. Sulbactam inhibits the action of beta-lactamase, an enzyme produced by bacteria to destroy antibiotics (ampicillin).
People allergic to penicillin should not take Synmega 250mg/125mg Tablet as they may develop cross-sensitivity (sensitivity to drugs with similar structures). Synmega 250mg/125mg Tablet contains ampicillin, which has a similar structure to that of penicillin.
You are recommended to avoid taking Synmega 250mg/125mg Tablet if you have infectious mononucleosis (viral infection with a sore throat and fever) and colitis (inflammation of the intestine), as Synmega 250mg/125mg Tablet worsens these conditions.
Synmega 250mg/125mg Tablet may decrease the effectiveness of oral contraceptives. Therefore, discuss with your doctor about other non-hormonal contraceptives such as condoms, diaphragms, etc.
Alcohol
Caution
It is not known whether the Synmega 250mg/125mg Tablet may interact with alcohol.
Pregnancy
Caution
Synmega 250mg/125mg Tablet should be used in pregnancy only if clinically needed and when the benefits outweigh the risks.
Breast Feeding
Caution
Synmega 250mg/125mg Tablet may pass into breast milk in small amounts. So, it should be used with caution in breastfeeding.
Driving
Caution
It is not known whether Synmega 250mg/125mg Tablet can affect your driving ability. Avoid driving if you experience any undesirable effects that affect your alertness.
Liver
Caution
Synmega 250mg/125mg Tablet should be used with caution in patients with liver diseases as it may affect liver function. Your doctor may adjust the dose if required based on your condition.
Kidney
Caution
Synmega 250mg/125mg Tablet should be used with caution in patients with kidney diseases as it may cause nephrotoxicity (damage to the kidney). Your doctor may adjust the dose if required based on your condition.
Children
Caution
Synmega 250mg/125mg Tablet should be used in children only if clinically needed. The dose is based on the age, body weight and medical history of your child.
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About Synmega 250mg/125mg Tablet
Synmega 250mg/125mg Tablet belongs to the group of medications called ‘antibiotics’ used to treat bacterial infections. Bacterial infections are caused by the multiplication of harmful bacteria inside or on the body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. Symptoms of bacterial infection vary depending on the organ affected by bacteria.
Synmega 250mg/125mg Tablet contains Ampicillin and Sulbactam. Ampicillin is a penicillin antibiotic. It has bactericidal action (kills bacteria). It works by preventing the formation of the cell wall (the outer protective layer of bacteria, which is essential for its survival) by preventing protein synthesis. Sulbactam is a beta-lactamase inhibitor. It broadens the spectrum of antibacterial activity by inhibiting the action of beta-lactamase, an enzyme produced by bacteria that can destroy antibiotics. Synmega 250mg/125mg Tablet is recommended for only bacterial infections and doesn’t treat viral infections.
Take this medicine exactly as prescribed by the doctor. The common side effects of Synmega 250mg/125mg Tablet are nausea, vomiting, headache, stomach pain and diarrhoea. These side effects are usually mild and temporary. However, if any of these side effects persist or get worse, inform your doctor immediately.
It is not recommended to take Synmega 250mg/125mg Tablet if you are allergic to penicillin, any other antibiotics, or the contents of Synmega 250mg/125mg Tablet. Synmega 250mg/125mg Tablet should not be given to people with infectious mononucleosis (viral infection with a sore throat and fever) and colitis (inflammation of the intestine). It should be used with caution in patients with kidney impairment. Do not discontinue or abruptly stop the medication, as it may lead to antibiotic resistance, a condition in which bacteria become resistant to antibiotics. Synmega 250mg/125mg Tablet should be used with caution in children, pregnant women, breastfeeding mothers and elderly people. It is not known whether Synmega 250mg/125mg Tablet can interact with alcohol or may affect your ability to drive. So, please discuss with your doctor the possible risks and benefits before taking this medicine.
Uses of Synmega 250mg/125mg Tablet
Medicinal Benefits
Synmega 250mg/125mg Tablet contains Ampicillin and Sulbactam. Ampicillin is a penicillin antibiotic that treats the infection by killing the bacteria. Sulbactam is a beta-lactamase (an enzyme produced by bacteria that can destroy antibiotics) inhibitor and prevents the destruction of ampicillin from the bacteria. Synmega 250mg/125mg Tablet has broad-spectrum activity and is effective against both gram-positive and gram-negative bacteria. It is used to treat bacterial infections such as skin infections, gynaecological infections and intra-abdominal infections.
Directions for Use
Side Effects of Synmega 250mg/125mg Tablet
Drug Warnings
If you notice watery and bloody stools with or without stomach cramps and fever, inform your doctor immediately as Synmega 250mg/125mg Tablet may cause diarrhoea, like many antibiotics. This condition usually resolves after the discontinuation of treatment. However, some patients may experience this condition even after two or more months after the antibiotic treatment. In addition, the severity of diarrhoea may range from mild conditions to severe colitis (inflammation of the intestine). Do not discontinue or abruptly stop the medication, as it may lead to antibiotic resistance, a condition in which bacteria become resistant to antibiotics. Synmega 250mg/125mg Tablet should not be used in patients with mononucleosis (viral infection with a sore throat and fever), as this medicine causes a skin rash. Synmega 250mg/125mg Tablet may cause superinfection (an additional infection that occurs with other microbes) on prolonged use. So, please do not use it for longer periods than your doctor intended.
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