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Written By Veda Maddala , M Pharmacy
Reviewed By Sunny S , MBBS
48 Hrs returnable
COD available

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Composition :

ITRACONAZOLE-200MG

Manufacturer/Marketer :

Glenmark Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTIFUNGALS

Country of origin

India

Manufacturer/Marketer address

Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai – 400 026.
Other Info - SYN0236

Author Details

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FAQs

You are not recommended to take Syntran 200 Capsule with simvastatin as co-administration of these two medicines may cause muscle weakness, unexplained muscle pain or tenderness, dark coloured urine, fever or flu symptoms. However, please consult a doctor before using Syntran 200 Capsule with other medicines.

No, Syntran 200 Capsule is not recommended for use during pregnancy as it may cause harm to the fetus. Also, it is advised to use effective contraceptive measures while taking Syntran 200 Capsule and after 2 months of stopping treatment with Syntran 200 Capsule . However, please inform your doctor if you are pregnant, planning for pregnancy or breastfeeding before taking Syntran 200 Capsule .

Syntran 200 Capsule may cause temporary or permanent hearing loss in some people. It is not necessary for everyone taking Syntran 200 Capsule to experience this adverse effect. However, if you notice any changes in hearing, stop taking Syntran 200 Capsule and consult a doctor immediately.

You are advised to take antacids (drugs used to reduce acid in the stomach) such as omeprazole, pantoprazole and esomeprazole at least 1 hour before or 2 hours after taking Syntran 200 Capsule as co-administration of these medicines at the same time may reduce the effectiveness of Syntran 200 Capsule because antacids decrease the absorption and blood levels of Syntran 200 Capsule . However, please consult a doctor before taking other medicines with Syntran 200 Capsule .

Yes, fungal infection is a contagious skin condition which spreads from one person to another through direct skin to skin contact or by contact with contaminated soil or surfaces and infected animals. Therefore, it is recommended to avoid close direct contact until the infection is clear and avoid sharing things with the infected person as it can also spread the infection.

You are not recommended to stop taking Syntran 200 Capsule without consulting your doctor as it may cause recurring infection. Therefore, take Syntran 200 Capsule for as long as your doctor has prescribed it, and if you experience any difficulty while taking Syntran 200 Capsule , please consult your doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

Avoid consumption of alcohol with Syntran 200 Capsule as it may increase the risk of liver problems and other adverse effects.

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Pregnancy

Unsafe

Syntran 200 Capsule is category C pregnancy drug and is unsafe for pregnant women as it may cause harm to the unborn baby. Therefore, inform your doctor if you are pregnant or planning for pregnancy before taking Syntran 200 Capsule .

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Breast Feeding

Caution

Syntran 200 Capsule is excreted in human milk and may harm the baby. Therefore, Syntran 200 Capsule is given to breastfeeding mothers only if doctor thinks benefits are greater than risks.

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Driving

Caution

Syntran 200 Capsule may cause dizziness, hearing loss, double or blurred vision in some people. Therefore, drive only if you alert after taking Syntran 200 Capsule .

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Liver

Caution

Take Syntran 200 Capsule with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Syntran 200 Capsule with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Syntran 200 Capsule is not recommended for children below 12 years as the safety and effectiveness were not established.

About Syntran 200 Capsule

Syntran 200 Capsule belongs to a class of drugs called antifungals used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. Fungal infection is a disease in which a fungus attacks the tissue and causes infection. Fungal infections may be contagious (spread from one person to another).

Syntran 200 Capsule contains Itraconazole, an antifungal that works by inhibiting the production of ergosterol (a main component of cell membranes of fungi). Thereby, weakens and damages the fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, causes the main components of fungal cells to leak out and kill fungi and clear the fungal infection.

Take Syntran 200 Capsule as prescribed. Your doctor will advise you on how often you take Syntran 200 Capsule based on your medical condition. Some people may experience nausea, headache, diarrhoea, tiredness, cough, cold, throat pain, back pain and stomach pain. Most of these side effects of Syntran 200 Capsule do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Syntran 200 Capsule or any other medicines, please tell your doctor. Syntran 200 Capsule is a pregnancy category C drug and may cause harm to the unborn baby. However, if you are pregnant, planning for pregnancy or a nursing mother, it is advised to consult a doctor before using Syntran 200 Capsule . Do not take Syntran 200 Capsule if you have or had heart failure as it may cause severe life-threatening adverse effects. If you have kidney, liver, heart or lung problems, inform your doctor before taking Syntran 200 Capsule . Avoid taking fentanyl (a strong opioid narcotic medicine) with Syntran 200 Capsule as it may cause severe breathing problems and can even lead to death. If you experience numbness or tingling in your hands or feet, stop taking Syntran 200 Capsule and consult your doctor immediately as they might be symptoms of nerve damage.

Uses of Syntran 200 Capsule

Fungal infections

Medicinal Benefits Mweb

Medicinal Benefits

Syntran 200 Capsule is an antifungal used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. The fungal cell membranes are essential for their survival as they prevent the entry of unwanted substances into the cells and stops the leakage of cell contents. Syntran 200 Capsule inhibits the production of ergosterol (a main component of cell membranes of fungi). Thereby, weakens and damages the fungal cell membranes causing the main components of fungal cells to leak out. Thus, kills fungi and clears the fungal infection.

Directions for Use

Tablet: Take it with food to avoid stomach upset or as advised by the doctor. Swallow the whole tablet with a glass of water. Do not break, crush or chew it. If you are taking any stomach acid suppressor or have achlorhydria (stomach does not produce hydrochloric acid), take Syntran 200 Capsule with cola. Oral suspension: Shake the bottle well before use and take it on an empty stomach at least 1 or 2 hours before meals as prescribed by your doctor with a measuring cup or spoon provided.

Side Effects of Syntran 200 Capsule

  • Nausea
  • Headache
  • Diarrhoea
  • Tiredness
  • Cough
  • Cold
  • Throat pain
  • Back pain
  • Stomach pain

Drug Warnings

If you are known to be allergic to Syntran 200 Capsule or any other medicines, please tell your doctor. Syntran 200 Capsule is a pregnancy category C drug and may cause harm to the unborn baby. However, if you are pregnant, planning for pregnancy, or are a nursing mother, it is advised to consult a doctor before using Syntran 200 Capsule . Avoid taking fentanyl (a strong opioid pain killer narcotic medicine) with Syntran 200 Capsule , as it may cause severe breathing problems and can even lead to death. Do not take Syntran 200 Capsule if you had heart failure as it may cause severe life-threatening adverse effects. If you experience a yellow colour change of your eyes or skin, dark coloured urine, stomach pain, pale stools, loss of appetite, unusual tiredness, vomiting or nausea, stop taking Syntran 200 Capsule and consult a doctor immediately as they might be symptoms of liver failure. If you have kidney, liver, heart, or lung problems, inform your doctor before taking Syntran 200 Capsule .

Drug-Drug Interactions

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ItraconazoleEplerenone
Critical
ItraconazoleFelodipine
Critical

Drug-Drug Interactions

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ItraconazoleEplerenone
Critical
How does the drug interact with Syntran 200 Capsule:
The blood levels and effects of eplerenone may be greatly increased when combined with Syntran 200 Capsule.

How to manage the interaction:
Although there is a possible interaction between Eplerenone and Syntran 200 Capsule, it is not recommended; they can be taken if prescribed by a doctor. Consult a doctor if you have complications such as hyperkalemia (high blood potassium), which in extreme circumstances can result in kidney problems, muscle paralysis, and an irregular heartbeat. Without first consulting your doctor, never stop taking medicines.
ItraconazoleFelodipine
Critical
How does the drug interact with Syntran 200 Capsule:
The blood levels and effects of felodipine may be considerably increased by taking Syntran 200 Capsule together with felodipine.

How to manage the interaction:
Although there is a possible interaction between felodipine and Syntran 200 Capsule, they can be taken if prescribed by a doctor. Consult a physician if you have an irregular heartbeat, Edema (accumulation of fluid in hands or legs), or abnormally low blood pressure. Without first consulting a doctor, never stop taking medicines.
ItraconazoleSilodosin
Critical
How does the drug interact with Syntran 200 Capsule:
Coadministration of Syntran 200 Capsule with Silodosin can increase the blood levels and effects of Silodosin, which may lead to side effects including extremely low blood pressure and increased heart rate.

How to manage the interaction:
Taking Syntran 200 Capsule with Silodosin together is not recommended as it can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, or heart palpitation. Do not discontinue any medications without consulting a doctor.
ItraconazoleTicagrelor
Critical
How does the drug interact with Syntran 200 Capsule:
The blood levels and effects of ticagrelor may be greatly increased when combined with Syntran 200 Capsule.

How to manage the interaction:
Syntran 200 Capsule and ticagrelor may interact, however if prescribed by a physician, they can be used together. While receiving therapy, you should consult a doctor if you develop any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Without consulting a doctor, never stop taking any medication.
ItraconazoleColchicine
Critical
How does the drug interact with Syntran 200 Capsule:
Coadministration of colchicine with Syntran 200 Capsule may increase the blood levels of colchicine, increasing the risk of serious side effects.

How to manage the interaction:
Colchicine with Syntran 200 Capsule can be taken if prescribed by a doctor, despite the possibility of an interaction. However, contact a doctor if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet. Do not stop using any medications without first talking to your doctor.
ItraconazoleSolifenacin
Critical
How does the drug interact with Syntran 200 Capsule:
The blood levels and effects of solifenacin may be greatly increased when combined with Syntran 200 Capsule.

How to manage the interaction:
Solifenacin and Syntran 200 Capsule may interact, however, if recommended by a physician, they are safe to consume. Consult a doctor if you feel sleepy, or uneasy, have an irregular heartbeat, have blurry vision, have trouble urinating, have a dry mouth, a headache, have digestive problems, or have constipation. Without consulting a doctor, never stop taking any medication.
ItraconazoleCisapride
Critical
How does the drug interact with Syntran 200 Capsule:
The blood level of Cisapride may be significantly raised by combining Cisapride with Syntran 200 Capsule.

How to manage the interaction:
Despite the possibility of an interaction when cisapride and Syntran 200 Capsule are combined, they can be taken if a doctor prescribes them. Consult a doctor if you develop any side symptoms, such as fainting, lightheadedness, dizziness, or rapid or pounding heartbeats. Without consulting a doctor, never stop taking any medication. Note: Cisapride is no longer available in the market.
ItraconazoleErgotamine
Critical
How does the drug interact with Syntran 200 Capsule:
The blood levels and effects of ergotamine may be greatly increased when combined with Syntran 200 Capsule.

How to manage the interaction:
Ergotamine and Syntran 200 Capsule may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you experience a severe headache, shortness of breath, blurred vision, confusion, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of the fingers or toes, pale or cold skin, or chest pain or tightness. Without first consulting your doctor, never stop taking medicines.
ItraconazoleNisoldipine
Critical
How does the drug interact with Syntran 200 Capsule:
The blood levels and effects of nisoldipine may be greatly increased when used with Syntran 200 Capsule.

How to manage the interaction:
Nisoldipine and Syntran 200 Capsule may interact, but if prescribed by a doctor, they can be used together. Consult a physician if you have symptoms that include an irregular heartbeat, accumulation of fluid in legs or hands, or abnormally low blood pressure. Without consulting a doctor, never stop taking any medication.
ItraconazoleMethylergometrine
Critical
How does the drug interact with Syntran 200 Capsule:
Co-administration of Methylergometrine and Syntran 200 Capsule may increase the blood levels of Methylergometrine.

How to manage the interaction:
Methylergometrine and Syntran 200 Capsule may interact, but if prescribed by a doctor, they can be used together. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

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ITRACONAZOLE-200MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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ITRACONAZOLE-200MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consuming Grapefruit, Grapefruit juice with Syntran 200 Capsule may impair the absorption of Syntran 200 Capsule, resulting in decreased antifungal effects. Avoid consuming Grapefruit and grapefruit juice with Syntran 200 Capsule.

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • ESOMEPRAZOLE
  • OMEPRAZOLE
  • PANTOPRAZOLE
  • FLUTICASONE
  • BUDESONIDE
  • HYDROCODONE
  • WARFARIN
  • SIMVASTATIN
  • TERFENADINE
  • ALPRAZOLAM

Habit Forming

No

Special Advise

  • Regular blood tests are recommended before and while taking Syntran 200 Capsule to monitor liver functioning especially if you have any liver problems.

Diet & Lifestyle Advise

  • Regularly change your socks and wash your feet. Avoid shoes that make your feet sweaty and hot.
  • In wet places such as changing rooms and gym showers, don’t walk on barefoot to prevent fungal infections.
  • Do not scratch the affected area of skin as it can spread the infection to other body parts.
  • Avoid sharing towels, combs, bedsheets, shoes or socks with others.
  • Wash your bed sheets and towels regularly.

Syntran 200 Capsule Substitute

Substitutes safety advice
  • Itracip 200 mg Capsule 10's

    by Others

    24.75per tablet
  • Candiforce-200 Capsule 10's

    by Others

    22.28per tablet
  • Canditral 200 Capsule 10's

    by Others

    22.28per tablet
  • Itaspor 200 Capsule 10's

    by AYUR

    22.28per tablet
  • Itralase 200 Capsules 10's

    by AYUR

    22.28per tablet
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