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  3. Tagrisso 80Mg Tablet 10'S

Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Composition :

OSIMERTINIB-80MG

Manufacturer/Marketer :

Astra Zeneca Pharma India Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Tagrisso 80Mg Tablet

Tagrisso 80Mg Tablet belongs to a class of protein kinase inhibitors primarily used to manage or treat lung cancer. Lung cancer is a disease that causes malignant (cancer) cells to grow in lung tissues.

Tagrisso 80Mg Tablet contains Osimertinib, which blocks proteins on cancer cells that encourage cancer growth. Thus, it reduces or stops the progression of advanced cancer.

To treat your condition effectually, continue using Tagrisso 80Mg Tablet for as long as your doctor has prescribed it. The most common adverse reactions are diarrhoea, rash, dry skin, nail toxicity, stomatitis (inflammation of the oral mucosa), fatigue (feeling overtired), decreased appetite, and low blood cell counts. You should talk to your doctor if you persistently experience these side effects.

Before taking the Tagrisso 80Mg Tablet , inform your doctor about all your allergic or hypersensitivity reactions to medicines or food. Tagrisso 80Mg Tablet can cause fetal harm when administered to a pregnant woman. It is critical not to become pregnant or get pregnant while undergoing therapy and for several months after the treatment. Using effective contraceptive methods is recommended while on therapy with Tagrisso 80Mg Tablet . Contact your doctor immediately if you or your partner becomes pregnant while undergoing therapy. Breastfeeding is usually not advised during this treatment. Alcohol should be avoided during treatment with this medicine. Safety and effectiveness in children have not been established.

Uses of Tagrisso 80Mg Tablet

Lung Cancer

Directions for Use

Tagrisso 80Mg Tablet should be swallowed as a whole with a glass of water. Do not crush, chew, or break the tablets. The doctor determines the dose and duration of the treatment based on your health condition.

Medicinal Benefits

Tagrisso 80Mg Tablet contains Osimertinib, which belongs to a class of protein kinase inhibitors primarily used to manage or treat lung cancer. Osimertinib blocks proteins in cancer cells that encourage the cancer to grow. Osimertinib can temporarily reduce or stop the progression of advanced cancer. Following surgery, Osimertinib may help prevent the cancer from returning.

Storage

Store in a cool and dry place away from sunlight
Side effects of Tagrisso 80Mg Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
  • Apply moisturizer immediately after showering or bathing.
  • Use a moisturizer containing lanolin, petroleum jelly, glycerine, hyaluronic acid or jojoba oil.
  • Do not use hot water for bathing. Instead use warm water and limit showers and bath to 5 to 10 minutes.
  • Apply a sunscreen with SPF-30 or higher.
  • Avoid harsh soaps, detergents and perfumes.
  • Do not scratch or rub the skin.
  • Drink adequate water to prevent dehydration.
  • Wear pants, full sleeves and a wide-brimmed hat while going out in the sun.
  • Soak the infected nail in warm water for 10 to 20 minutes, a few times a day.
  • Apply topical antibiotic ointment as advised by the doctor.
  • Avoid irritants and excessive moisture.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
  • Consult a hematologist or doctor to identify the cause of thrombocytopenia (Decreased Platelet Count) and plan treatment.
  • Foods rich in vitamins B12, C, folate, and iron may help boost platelet count.
  • Avoid heavy lifting, bending, or straining to reduce bleeding risk.
  • Stay hydrated by drinking plenty of water to help prevent bleeding.
  • Avoid alcohol and tobacco to prevent lowering platelet count and reduce bleeding risk.
  • Regular blood tests help monitor platelet count and detect any changes.

Drug Warnings

Before taking the Tagrisso 80Mg Tablet , inform your doctor about all your medical conditions, sensitivities, and medications you are using. Exposure of an unborn child to this medication could cause birth defects, so you should not become pregnant or father a child while on this medication. Effective birth control is required throughout treatment and at least six weeks after treatment for women and four months after treatment for males. You should not breastfeed while taking this medication for two weeks after your last dose. Unless the doctor suggests, do not use any other medicine, including herbal or vitamin supplements. In rare cases, Tagrisso 80Mg Tablet therapy may lead to Interstitial lung disease (ILD)/Pneumonitis. Dyspnea, cough, and fever are the symptoms which may be indicative of ILD. If these symptoms worsen, contact your doctor right away. If ILD is confirmed, your doctor will discontinue the Tagrisso 80Mg Tablet therapy.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Tagrisso 80Mg Tablet:
Tagrisso 80Mg Tablet's blood levels may rise if itraconazole and Tagrisso 80Mg Tablet are taken together.

How to manage the interaction:
Tagrisso 80Mg Tablet and itraconazole may interact, but if a doctor prescribes them, you can still use them. If you develop vomiting, diarrhoea, mouth sores, lightheadedness, fainting, shortness of breath, swelling, or a racing heart, contact a doctor. Never discontinue taking a medication without consulting a doctor.
How does the drug interact with Tagrisso 80Mg Tablet:
Coadministration of Amiodarone together with Tagrisso 80Mg Tablet may raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Even though Amiodarone and Tagrisso 80Mg Tablet interact, they can be used if prescribed by a doctor. If you have cardiac problems or electrolyte imbalances, you may be at greater risk. If you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, get medical attention. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tagrisso 80Mg Tablet:
Using Tagrisso 80Mg Tablet with Adenosine can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Adenosine with Tagrisso 80Mg Tablet together can result in an interaction, but it can be taken if your doctor has advised it. It's important to keep an eye on your qt interval. If you experience shortness of breath, palpitations, chest discomfort, or dizziness, contact a doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Tagrisso 80Mg Tablet:
Using Tagrisso 80Mg Tablet together with lenvatinib can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is an interaction between lenvatinib and Tagrisso 80Mg Tablet, they can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tagrisso 80Mg Tablet:
Using Moxifloxacin together with Tagrisso 80Mg Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although taking Moxifloxacin and Tagrisso 80Mg Tablet together can cause an interaction, it can be taken if a doctor has suggested it. If you experience - a fast or irregular heartbeat, dizziness, or difficulty breathing - make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Tagrisso 80Mg Tablet:
Use of atomoxetine with Tagrisso 80Mg Tablet can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Although taking Atomoxetine and Tagrisso 80Mg Tablet together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Tagrisso 80Mg Tablet:
Co-administration of Tagrisso 80Mg Tablet and Haloperidol can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Tagrisso 80Mg Tablet with Haloperidol can lead to an interaction, it can be taken when your doctor advises. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Tagrisso 80Mg Tablet:
Taking Abiraterone with Tagrisso 80Mg Tablet can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Abiraterone with Tagrisso 80Mg Tablet together can result in an interaction; it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or a rapid heartbeat. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tagrisso 80Mg Tablet:
Taking Tagrisso 80Mg Tablet with Cladribine can increase the risk of developing serious infections.

How to manage the interaction:
Although there is a possible interaction between Cladribine and Tagrisso 80Mg Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Tagrisso 80Mg Tablet:
When Tagrisso 80Mg Tablet is taken with Infliximab, it can increase the risk or severity of developing serious infections.

How to manage the interaction:
Taking Infliximab with Tagrisso 80Mg Tablet together can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you pee, it's important to contact a doctor right away. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • After your treatment begins, several dietary adjustments can help you control side effects.
  • Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
  • Plant-based proteins are among the greatest meals during chemotherapy or other cancer treatments. They have the highest concentrations of vitamins and minerals, such as nuts, seeds, beans and legumes.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugars.

Habit Forming

No

Therapeutic Class

KINASE INHIBITORS

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Tagrisso 80Mg Tablet contains Osimertinib, a protein kinase inhibitor that works by blocking the abnormal protein which can cause uncontrolled cell growth and cancer; thus, it slows or stops cancer growth.

While taking Tagrisso 80Mg Tablet , visit your doctor at all the appointments to ensure treatment works. Regular monitoring of blood and lipid tests and weight checks are required. An effective way of contraception should be used by both men and women while taking the Tagrisso 80Mg Tablet .

This medicine may reduce the quantity of platelets in your blood significantly. Platelets are cells that aid in the clotting of blood. If your platelet count is low, you may bruise or bleed easily. Inform your doctor if you experience any unexplained bruises or bleeding. You may require a drip to receive more platelets. This is referred to as a platelet transfusion.

Tagrisso 80Mg Tablet may cause infertility. Discuss with your doctor all the risks of taking this medication.

Drug-Drug Interactions Checker List

  • AMPRENAVIR
  • ATAZANAVIR
  • EFAVIRENZ
  • ERYTHROMYCIN
  • GATIFLOXACIN
  • ESCITALOPRAM
  • FINGOLIMOD
  • HALOTHANE
  • TYPHOID VACCINE LIVE
  • SMALLPOX VACCINE
  • ROTAVIRUS VACCINE
  • QUINIDINE

Special Advise

  • Keep all appointments with your doctor and the laboratory. Your doctor will order certain tests to check your body's response to Tagrisso 80Mg Tablet .
  • Pregnancy testing is recommended prior to starting treatment with Tagrisso 80Mg Tablet .

Disease/Condition Glossary

Lung cancer: Lung cancer is one of the most common and serious types of cancer. Lung cancer is a disease that causes malignant (cancer) cells to grow in lung tissues. Primary lung cancer is cancer that begins in the lungs. Secondary lung cancer is cancer that spreads to the lungs from elsewhere in the body. There are usually no signs or symptoms in the early stages of lung cancer. Still, many people experience symptoms such as a chronic cough, coughing up blood, persistent dyspnea, unexplained tiredness and weight loss, and an ache or pain when breathing or coughing.

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