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Written By Divya L , PharmaD
Reviewed By Veda Maddala , M Pharmacy
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

GENTAMICIN-0.3% W/V

Manufacturer/Marketer :

Warren Pharmaceuticals Pvt Ltd

Consume Type :

EYE/EAR

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTIBIOTICS

Country of origin

India
Other Info - TAM0008

Author Details

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FAQs

TAMIGEN DROPS 5ML consists of Gentamicin, an antibiotic that prevents the synthesis of essential proteins required by bacteria to carry out vital functions. Thus, it treats bacterial infections of the eye and ear.

It is advised to remove your contact lens while administering eye drops. Also, remember to wash your hands before and after administering eye drops to avoid contamination.

If you use other eye ointments/drops along with TAMIGEN DROPS 5ML, it is advised to maintain a gap of at least 5-10 minutes after each administration. Also, use eye drops before applying any ointments.

Avoid the contact of the dropper or tip with fingers, eyes, and eyelids. Topical eye products, when contaminated by patients with eye diseases, bacterial keratitis (an infection of the cornea) and ocular infections (eye infections) may occur, which result in vision loss.

You must maintain at least a 20-30 minutes gap after instilling TAMIGEN DROPS 5ML if you use more than one ear drop formulation.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

Alcohol consumption may worsen the side effects like dizziness; hence please avoid or limit alcohol intake while being treated with TAMIGEN DROPS 5ML.

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Pregnancy

Caution

It is advised to consult your doctor if you plan to conceive or are already pregnant before starting TAMIGEN DROPS 5ML.

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Breast Feeding

Caution

There are limited studies on how TAMIGEN DROPS 5ML affects breastfed infants. Please consult your doctor before using TAMIGEN DROPS 5ML if you are breastfeeding.

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Driving

Caution

TAMIGEN DROPS 5ML may cause side effects like blurry vision or dizziness, affecting your driving ability. Do not drive or operate machinery in such cases. Drive only when you are alert and have clear vision.

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Liver

Caution

Let your doctor know if you have any history of liver diseases or hepatic impairment before starting TAMIGEN DROPS 5ML.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases before starting TAMIGEN DROPS 5ML.

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Children

Caution

TAMIGEN DROPS 5ML should be used for children only when advised by a doctor.

About TAMIGEN DROPS 5ML

TAMIGEN DROPS 5ML is an antibiotic medicine that treats bacterial infections of the eye and ear. It is used to treat infections like conjunctivitis (inflammation of the mucous membrane (conjunctiva) of the eye), keratitis (inflammation of the cornea), keratoconjunctivitis (inflammation of conjunctiva and cornea), blepharitis (inflammation of the eyelids), blepharoconjunctivitis (inflammation of conjunctiva and eyelids), corneal ulcers, and otitis externa (inflammation of the ear).

TAMIGEN DROPS 5ML is composed of Gentamicin, an aminoglycoside antibiotic. It prevents bacteria from synthesising essential proteins required to carry out vital functions. It has broad-spectrum activity against aerobic Gram-positive and Gram-negative bacteria. 

TAMIGEN DROPS 5ML is for external use only. Common side effects of TAMIGEN DROPS 5ML, when used as eye drops, include local sensitivity in the eye, irritation, itching, redness, burning or a stinging sensation at the application site, and blurred vision. Side effects of TAMIGEN DROPS 5ML, when used as ear drops, include local sensitivity in the ear, burning or stinging sensation, itching, skin inflammation, and vestibular disorder/dizziness. These side effects may not occur in every patient using this medication and differ individually. If the side effects persist longer or worsen, please seek a doctor's advice.

Let your doctor know if you are allergic to TAMIGEN DROPS 5ML or any other medications. Please inform your doctor if you have any liver/kidney diseases, myasthenia gravis (muscle weakness), hearing problems, and a perforated eardrum before using TAMIGEN DROPS 5ML. Pregnant and breastfeeding mothers should consult the doctor before starting TAMIGEN DROPS 5ML. This medicine may cause temporary blurred vision; hence drive only when you are alert and have clear vision. Avoid or limit alcohol consumption during the treatment since TAMIGEN DROPS 5ML may cause dizziness. TAMIGEN DROPS 5ML should be used for children only when advised by a doctor.

Uses of TAMIGEN DROPS 5ML

Bacterial infections of the eye and ear.

Medicinal Benefits Mweb

Medicinal Benefits

TAMIGEN DROPS 5ML treats various bacterial infections of the eye and ear. TAMIGEN DROPS 5ML consists of Gentamicin, an antibiotic that prevents the synthesis of essential proteins required by bacteria to carry out vital functions. TAMIGEN DROPS 5ML may also be given as a treatment to prevent infections in the injured eye or ear.

Directions for Use

Eye drops: Tilt your head back and pull your lower eyelid downwards and outwards. Gently squeeze the dropper and instil the eye drops in the eye/eyes. Blink a few times to spread the medication inside your eye.Ear drops: Tilt your head to the side and instil the ear drops inside the ear. Keep your head tilted for a minute to let the drops soak in.

Side Effects of TAMIGEN DROPS 5ML

Eye drops:

  • Local sensitivity in the eye
  • Irritation
  • Itching
  • Redness
  • Burning or a stinging sensation
  • Blurred vision

Ear drops:

  • Local sensitivity in the ear
  • Burning or stinging sensation
  • Itching
  • Skin inflammation
  • Vestibular disorder/dizziness 

Drug Warnings

Inform your doctor if you have any allergic reactions to Gentamicin before starting TAMIGEN DROPS 5ML. Avoid touching the dropper with bare hands or taking it closer to the eyelids/ear while administering since it contaminates the dropper tip and solution. If you wear contact lenses, remove them while administering the medicine into the eye. It is advised to check with your doctor before using TAMIGEN DROPS 5ML if you are pregnant or breastfeeding. Avoid driving or operating machines since the administration of TAMIGEN DROPS 5ML may cause temporary blurred vision for a while. Avoid or limit alcohol consumption during the treatment since TAMIGEN DROPS 5ML may cause dizziness. TAMIGEN DROPS 5ML should be used for children only when advised by a doctor.

Drug-Drug Interactions

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GentamicinColistin
Severe
GentamicinTacrolimus
Severe

Drug-Drug Interactions

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GentamicinColistin
Severe
How does the drug interact with Tamigen Drops 5ml:
Co-administration of Colistin with Tamigen Drops 5ml can increase the levels and risk of Colistin side effects.

How to manage the interaction:
Although there is a possible interaction between Colistin and Tamigen Drops 5ml, you can take these medicines together if prescribed by your doctor. However, if you experience weight gain or loss suddenly, muscle pain, dizziness, or palpitations, call your doctor right away. Do not stop using any medications without a doctor's advice.
GentamicinTacrolimus
Severe
How does the drug interact with Tamigen Drops 5ml:
Taking tacrolimus with Tamigen Drops 5ml may cause kidney problems.

How to manage the interaction:
Although there is a possible interaction, Tamigen Drops 5ml can be taken with tacrolimus if prescribed by the doctor. However, consult the doctor if you experience symptoms of kidney damage such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
GentamicinMivacurium chloride
Severe
How does the drug interact with Tamigen Drops 5ml:
Co-administration of Mivacurium with Tamigen Drops 5ml can make it more effective as a therapy.

How to manage the interaction:
Taking Tamigen Drops 5ml with Mivacurium chloride together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have trouble breathing or feel like you can't breathe at all, it's important to contact a doctor right away. This is especially true if you're having difficulty breathing for a long time. Do not stop using any medications without talking to a doctor.
GentamicinEverolimus
Severe
How does the drug interact with Tamigen Drops 5ml:
Everolimus may cause kidney problems, and combining it with Tamigen Drops 5ml may increase that risk.

How to manage the interaction:
Although there is a possible interaction, Tamigen Drops 5ml can be taken with everolimus if prescribed by the doctor. Consult the doctor if you experience symptoms of kidney damage such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm.
GentamicinFoscarnet
Severe
How does the drug interact with Tamigen Drops 5ml:
Co-administration of Tamigen Drops 5ml with Foscarnet can increase the risk of kidney damage.

How to manage the interaction:
Although taking Tamigen Drops 5ml and Foscarnet together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms, it's important to contact your doctor right away: seizures, an irregular heart rhythm, feeling sick, swelling, sudden weight gain or loss, severe pain in your upper stomach, strong heartbeats, feeling dizzy, or chest pain. Do not stop using any medications without a doctor's advice.
GentamicinBumetanide
Severe
How does the drug interact with Tamigen Drops 5ml:
Taking Tamigen Drops 5ml can cause hearing loss, ringing in the ears, vertigo, and kidney problems, and combining it with bumetanide may increase the risk.

How to manage the interaction:
Although there is a possible interaction, Tamigen Drops 5ml can be taken with bumetanide if prescribed by the doctor. Consult the doctor if you experience hearing loss, ringing in the ears, vertigo, or kidney problems.
GentamicinIopamidol
Severe
How does the drug interact with Tamigen Drops 5ml:
Co-administration of Iopamidol with Tamigen Drops 5ml may increase the risk of kidney problems.

How to manage the interaction:
Co-administration of Tamigen Drops 5ml with Iopamidol can possibly result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on how much you pee. If you notice any changes, like peeing more or less than usual, it's a good idea to let your doctor know right away. These changes could be a sign of problems with your kidneys, diabetes, or other health issues. Other symptoms to watch out for include feeling sick, throwing up, not wanting to eat, gaining or losing weight suddenly, or having trouble breathing. Do not stop using any medications without a doctor's advice.
GentamicinDoxacurium chloride
Severe
How does the drug interact with Tamigen Drops 5ml:
Co-administration of Doxacurium with Tamigen Drops 5ml may increase the risk of side effects.

How to manage the interaction:
There may be a possibility of interaction between Tamigen Drops 5ml and Doxacurium chloride, but it can be taken if prescribed by a doctor. If you have trouble breathing or feel like you can't breathe at all, it's important to contact a doctor right away. This is especially true if you're having difficulty breathing for a long time. Do not discontinue any medications without consulting a doctor.
GentamicinHuman immunoglobulin
Severe
How does the drug interact with Tamigen Drops 5ml:
Co-administration of Human immunoglobulin with Tamigen Drops 5ml may raise the risk of kidney problems.

How to manage the interaction:
Although taking Human immunoglobulin and Tamigen Drops 5ml together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
GentamicinCidofovir
Severe
How does the drug interact with Tamigen Drops 5ml:
Taking Tamigen Drops 5ml with cidofovir can increase the risk of kidney problems.

How to manage the interaction:
Although taking Tamigen Drops 5ml and cidofovir together can possibly cause an interaction, it can be taken if your doctor has suggested it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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GENTAMICIN-0.3% W/VOther symptoms and signs involving the digestive system and abdomen
Severe
GENTAMICIN-0.3% W/VMyasthenia gravis and other myoneural disorders
Severe

Drug-Diseases Interactions

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GENTAMICIN-0.3% W/VOther symptoms and signs involving the digestive system and abdomen
Severe
How does the disease interact with Tamigen Drops 5ml:
Adequate hydration is critical for reducing the risk of oto- and nephrotoxicity associated with aminoglycoside usage. Dehydration should preferably be treated before starting therapy. Fluid status should be continuously maintained in patients who are at risk of dehydration, such as those who have severe and/or prolonged diarrhoea or vomiting. If indications of renal irritation appear during therapy, hydration should be increased as directed, followed by a dose reduction if necessary. If urine flow gradually decreases or azotemia worsens, therapy should be discontinued.

How to manage the interaction:
Dehydration should be corrected prior to initiation of therapy. Fluid status should be monitored closely in patients who may be at risk for dehydration, such as those with severe and/or prolonged diarrhea or vomiting. Therapy should be withdrawn if urinary output decreases progressively or azotemia (elevated levels of urea) increases.
GENTAMICIN-0.3% W/VMyasthenia gravis and other myoneural disorders
Severe
How does the disease interact with Tamigen Drops 5ml:
Aminoglycosides can elicit dose-related neuromuscular blockade and muscle weakness, especially in patients with neuromuscular illness or hypocalcemia, as well as in those undergoing general anaesthesia, neuromuscular blocking medications, or substantial transfusions of citrate-anticoagulated blood. Although neuromuscular blockade caused by aminoglycosides is usually self-limiting, it can occasionally result in respiratory paralysis. The most potent neuromuscular blocking drug in the class is regarded to be neomycin. However, the risk is greatest with large dosages instilled intraperitoneally or intrapleurally, or with fast intravenous administration of parenteral aminoglycosides. In patients with neuromuscular problems (e.g., myasthenia gravis, parkinsonian syndrome, botulism) or hypocalcemia, aminoglycoside therapy should be used with caution. If indications of respiratory paralysis appear during aminoglycoside therapy, the medicine should be stopped and, if necessary, mechanical breathing assistance administered.

How to manage the interaction:
Therapy should be administered cautiously in patients with neuromuscular disorders (e.g., myasthenia gravis, Parkinsonian syndrome, botulism) or hypocalcemia (low calcium levels). The drug should be discontinued and mechanical respiratory assistance provided if needed if signs of respiratory paralysis occur during therapy.
GENTAMICIN-0.3% W/VOther disorders of ear, not elsewhere classified
Severe
How does the disease interact with Tamigen Drops 5ml:
Aminoglycosides can harm the eighth cranial nerve, causing vestibular and/or auditory toxicity. Dizziness, nystagmus, vertigo, ataxia, tinnitus, and varied degrees of hearing impairment are among the symptoms. Following the discontinuation of the medicine, permanent hearing loss, including whole or partial irreversible bilateral deafness, may occur. Therapy with aminoglycosides, especially if extended (> 10 days), should be used with caution in patients with preexisting vestibular and/or auditory impairment, as it may delay or obfuscate the diagnosis of a drug-induced ototoxic impact. Patients should be adequately hydrated, the usual aminoglycoside dosage should not be exceeded, use with other ototoxic agents should be avoided, and peak and trough serum aminoglycoside concentrations should be determined on a regular basis and dosage adjusted to maintain desired levels.

How to manage the interaction:
Therapy should be administered with caution in patients with ototoxicity. The dosage should be reduced or therapy shoule be withdrawn if signs and symptoms of toxicity develop.
GENTAMICIN-0.3% W/VUnspecified kidney failure
Severe
How does the disease interact with Tamigen Drops 5ml:
Aminoglycosides have the potential to be ototoxic and nephrotoxic. Damage to the eighth cranial nerve can cause vestibular and/or auditory toxicities such as dizziness, nystagmus, vertigo, ataxia, tinnitus, and varied degrees of hearing impairment. Tubular necrosis, increases in BUN, nonprotein nitrogen, and serum creatinine concentration, decreases in urine specific gravity and creatinine clearance, proteinuria, and cells or casts in the urine are all signs of nephrotoxicity. Rarely, renal electrolyte wasting can cause hypocalcemia, hypomagnesemia, and hypokalemia, which can be accompanied with paresthesia, tetany, disorientation, and positive Chvostek and Trousseau symptoms. Although aminoglycoside-induced nephrotoxicity is often reversible after treatment withdrawal, mortality from uremia has happened on rare occasions. Patients with renal impairment should be treated with caution and at lower doses of aminoglycosides, as they may be at risk.Drug buildup increases the risk of oto- and nephrotoxicity. Patients should be adequately hydrated, the usual aminoglycoside dosage should not be exceeded, use with other neuro- and nephrotoxic agents should be avoided, and peak and trough serum aminoglycoside concentrations should be determined on a regular basis and dosage adjusted to maintain desired levels. If toxicity develops, renal and eighth cranial nerve function should be constantly monitored, and the dosage lowered or therapy discontinued.

How to manage the interaction:
Therapy should be administered cautiously at reduced dosages in patients with kidney impairment. Patients should be adequately hydrated, the dose should not be exceeded, and use with other neuro- and nephrotoxic agents should be avoided to minimize the risk of toxicity.

Drug-Drug Interactions Checker List

  • ETHACRYNIC ACID
  • FUROSEMIDE
  • AMPHOTERICIN B
  • CICLOSPORIN
  • CISPLATIN

Habit Forming

No

Special Advise

It is advised to contact your doctor if the infection symptoms persist or worsen after two weeks of treatment.

Diet & Lifestyle Advise

Ear infections:

  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Know your allergy triggers, such as pollen, dust and other factors.
  • Avoid getting things like shampoo, soap, and water into the ear as it can cause itching.
  • Do not poke or scratch the ear as it can cause damage to the ear canal, leading to inflammation. The inflamed skin can be infected by bacteria or fungi, which can cause infections in the ear.

Eye infections:

  • Do not rub your eyes even though some ophthalmic drugs make your eye itchy.
  • If you wear contact lenses: Clean and replace contact lenses more often. Never share contact lenses. Always remember to wash your hands before inserting and after removing the contact lens.
  • Avoid staring at the digital screens for longer durations. Rest your eyes every 20 minutes.
  • Avoid or limit the intake of alcohol and caffeine.
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