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  1. Home
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  3. Tmp 300mg Tablet

Tmp 300mg Tablet, Pack of 1 Tablet
Written By Divya L , PharmaD
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Know More

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Whats That

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Composition :

TRIMETHOPRIM-300MG

Manufacturer/Marketer :

Jagsonpal Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Therapeutic Class

ANTI- BACTERIALS

Country of origin

India
Other Info - TM61360

Author Details

Doctor image

Written By

Divya L

PharmaD

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 8, 2025 | 9:32 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Tmp 300mg Tablet contains 'Trimethoprim,' an antibacterial drug. It inhibits tetrahydrofolic acid formation and prevents the synthesis of bacterial nucleic acids and proteins that carry out bacteria's vital functions.

Tmp 300mg Tablet should be used with proper caution and doctor consultation if you have any anaemia (due to folate deficiency), kidney or liver diseases, diabetes, vitamin deficiency (folate or folic acid), blood disorders like bone marrow suppression and G6PD deficiency (a genetic disorder that causes red blood cells to breakdown), mineral imbalances like high potassium levels (hyperkalaemia) or low levels of sodium in the blood, porphyria (a disorder of skin sensitivity to light), and muscle weakness.

Tmp 300mg Tablet can affect the live vaccines like typhoid vaccine and decrease its effectiveness. Please consult a doctor before you start Tmp 300mg Tablet if you are undergoing any vaccinations.

Take this medication 2-3 hours before or after taking iron supplements, multivitamins, calcium supplements, antacids, and laxatives since these products prevent the absorption of Tmp 300mg Tablet. It is also advised to avoid dairy products like milk, yoghurt, and calcium-enriched juice.

Tmp 300mg Tablet can make your skin more sensitive to the harmful effects of the sunlight. Hence it is advised to use sunscreen and wear protective clothing while using Tmp 300mg Tablet. It is also recommended to avoid tanning booths and sunlamps.

It is recommended to complete the course of Tmp 300mg Tablet even if you feel better as it is an antibiotic, and stopping it midway may lead to recurring infections. Continue taking Tmp 300mg Tablet for as long as your doctor has prescribed to treat your condition effectually.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

Avoid alcohol consumption while taking Tmp 300mg Tablet to prevent unpleasant side-effects, such as fast heartbeats, warmth or redness under your skin, tingly feeling, nausea, and vomiting.

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Pregnancy

Unsafe

Tmp 300mg Tablet is not recommended during pregnancy since it interferes with folic acid formation, which plays a crucial role in developing the unborn baby's brain and spinal cord. Please consult your doctor before taking Tmp 300mg Tablet if you are pregnant or planning to conceive.

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Breast Feeding

Unsafe

Tmp 300mg Tablet is excreted into the breast milk. Please consult your doctor before taking Tmp 300mg Tablet if you are breastfeeding.

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Driving

Caution

It is unknown whether Tmp 300mg Tablet affects your ability to drive and operating machinery. Drive only if you are physically stable and mentally focussed. If you experience dizziness or fatigue after taking Tmp 300mg Tablet, do not drive or operate any machinery.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before taking Tmp 300mg Tablet.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases before taking Tmp 300mg Tablet.

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Children

Unsafe

Tmp 300mg Tablet is not recommended to children below 12 years.

Reference

  1. https://www.medicines.org.uk/emc/files/pil.5925.pdf
  2. https://www.drugs.com/mtm/trimethoprim.html
  3. https://www.webmd.com/drugs/2/drug-4083/trimethoprim-oral/details

About Tmp 300mg Tablet

Tmp 300mg Tablet belongs to the 'antibacterials' class of drugs, primarily used to treat bacterial infections of the ear, urinary tracts like cystitis (inflammation of the bladder) and respiratory tract. Bacterial infection occurs when harmful bacteria grow in the body and causes illness. It can infect any part of the body and multiply very quickly.

Tmp 300mg Tablet contains 'Trimethoprim,' an antibacterial drug. Trimethoprim is a folic acid inhibitor that inhibits tetrahydrofolic acid formation (a folic acid derivative essential for developing proteins and nucleic acids). Thus, Tmp 300mg Tablet prevents the synthesis of bacterial nucleic acids and proteins, which are the primary cursors for carrying out bacteria's vital functions. This process further inhibits bacterial growth.

Like all medicines, Tmp 300mg Tablet also causes side effects, although not everybody gets them. Common side effects of Tmp 300mg Tablet include diarrhoea, nausea, vomiting, stomach upset, loss of appetite, changes in taste, and headache. If any of these effects persist or worsen, seek medical advice promptly.

Brief your medical history to doctor before starting Tmp 300mg Tablet. Do not use Tmp 300mg Tablet while having vaccinations with live bacterial vaccines (typhoid vaccine) since Tmp 300mg Tablet may affect vaccines' activity. Tmp 300mg Tablet can make your skin more sensitive to the sun, hence wear sunscreen when you step out. It is advised to consult your doctor if you are pregnant or breastfeeding before taking Tmp 300mg Tablet.

Uses of Tmp 300mg Tablet

Bacterial infections.

Medicinal Benefits Mweb

Medicinal Benefits

Tmp 300mg Tablet contains 'Trimethoprim,' an antibacterial drug that treats bacterial infections of the ear, urinary tracts like cystitis (inflammation of the bladder), and respiratory tract. It also helps in treating chest infections and acne. Tmp 300mg Tablet is a folic acid inhibitor and inhibits tetrahydrofolic acid formation (a folic acid derivative essential for the formation of proteins and nucleic acids). Thus, Tmp 300mg Tablet prevents the synthesis of bacterial nucleic acids and proteins, which are the primary cursors for carrying out bacteria's vital functions. Tmp 300mg Tablet is also used to prevent the recurrence of urinary tract infections.

Directions for Use

Tablet: Swallow the tablet one hour before or two hours after meals, followed by a glass of water. Do not chew, crush or break it. Do not take it immediately before bed.Solution: Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided with the pack.

Side Effects of Tmp 300mg Tablet

  • Diarrhoea
  • Nausea
  • Vomiting
  • Stomach upset 
  • Loss of appetite 
  • Changes in taste 
  • Headache 

Drug Warnings

Older patients may be more prone to side effects when they have a history of hyperkalemia while using Tmp 300mg Tablet. Please inform your doctor if you are undergoing dialysis treatment since Tmp 300mg Tablet is moderately removed by haemodialysis. Your doctor may schedule the dosage after dialysis. Please undergo an examination to rule out CDAD's chances if you experience diarrhoea following Tmp 300mg Tablet therapy. Let your doctor know if you are undergoing any vaccinations with live bacterial vaccines (like typhoid vaccine) since Tmp 300mg Tablet may affect vaccines' activity. Tmp 300mg Tablet may induce photosensitivity and makes your skin more sensitive to the sun; hence wear sunscreen when you step out. Please seek medical advice if you are pregnant or breastfeeding before taking Tmp 300mg Tablet.

Drug-Drug Interactions Checker List

  • WARFARIN
  • HEPARIN
  • METHOTREXATE
  • REPAGLINIDE
  • PROCAINAMIDE
  • DIGOXIN
  • PYRIMETHAMINE
  • DAPSONE
  • PHENYTOIN
  • RIFAMPICIN
  • SPIRONOLACTONE
  • AMILORIDE

Habit Forming

No

Special Advise

  • Renal, hepatic, and blood function tests are advised during prolonged therapy to rule out any toxicity caused due to overdose of Tmp 300mg Tablet. 
  • Clostridium difficile associated diarrhoea (CDAD) is reported during usage of antibiotics like Trimethoprim. Please see your doctor if you experience prolonged diarrhoea.
  • Monitor your blood sugar levels regularly since Tmp 300mg Tablet may affect your blood glucose levels if you have diabetes.
  • Trimethoprim is moderately removed during dialysis, hence let your doctor know if you are undergoing dialysis treatment so that the dose can be scheduled after the dialysis.

Diet & Lifestyle Advise

  • Include more fibre enriched food in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fibre foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains like whole-grain bread, brown rice should be included in your diet.
  • Eating grapefruit during antibiotics treatment can prevent the body from utilizing Tmp 300mg Tablet properly. So, avoid intake of grapefruit or grapefruit juice with the antibiotic.
  • Avoid intake of alcoholic beverages with Tmp 300mg Tablet as it can make you dehydrated and affect your sleep. This can make more challenging for your body to aid the Tmp 300mg Tablet in fighting off infections.
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
  • Do not walk barefoot at places like gym showers to prevent bacterial infections.

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