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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Hari Kumar , MBBS
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

TOFACITINIB-11MG

Manufacturer/Marketer :

Goddres Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTIRHEUMATICS, DISEASE MODIFYING ANTIRHEUMATIC DRUGS (DMARDs)

Country of origin

India

Manufacturer/Marketer address

Unit No.304, A Wing, Western Edge Ii, Near Western Express Highway, Borivali (East), Mumbai 400066.
Other Info - TOF0100

Author Details

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FAQs

Tofagod-11 ER Tablet works by blocking Janus kinase enzyme, thereby lowers inflammation and symptoms associated with rheumatoid and psoriatic arthritis.

Hypertension/high blood pressure could be a side-effect of Tofagod-11 ER Tablet . Consult your doctor before taking Tofagod-11 ER Tablet if you have high blood pressure or if you are taking anti-hypertensive medicines.

Diarrhoea might be a side-effect of Tofagod-11 ER Tablet . Eat non-spicy meals and drink plenty of fluids to prevent dehydration if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Tofagod-11 ER Tablet might impair fertility in females of reproductive potential. It is not known if the effect is reversible. Therefore, talk to a doctor before starting Tofagod-11 ER Tablet if you are trying to become pregnant or if you have any concerns regarding this.

Tofagod-11 ER Tablet affects the immune system and might lower the ability of the immune system to fight infections. Inform your doctor if you have an active infection, if you have a condition that increases the chance of having infections, if you are taking immunosuppressants, medicines that affect the immune system or corticosteroids.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

It is not known if alcohol interacts with Tofagod-11 ER Tablet , so please consult a doctor.

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Pregnancy

Unsafe

Tofagod-11 ER Tablet must not be taken during pregnancy. If you are a woman of child-bearing potential, use effective contraception during the treatment with Tofagod-11 ER Tablet and for 4 weeks after discontinuation.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Tofagod-11 ER Tablet . Please consult a doctor if you have any concerns.

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Driving

Safe if prescribed

Tofagod-11 ER Tablet generally does not affect your ability to drive. However, drive or operate machinery only if you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this. Tofagod-11 ER Tablet is not recommended for patients with severe liver problems.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Tofagod-11 ER Tablet is not recommended for children below 18 years as safety and effectiveness were not established.

About Tofagod-11 ER Tablet

Tofagod-11 ER Tablet belongs to a group of medicines called Janus kinase inhibitors used to treat rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. Rheumatoid arthritis is an auto-immune disease (the body's immune system attacks its tissue) which leads to joint pain and damage. Psoriatic arthritis is an inflammatory condition of the joints, often associated with psoriasis. Ulcerative colitis is an inflammatory disease of the large intestine.
 
Tofagod-11 ER Tablet contains 'Tofacitinib' which works by blocking the Janus kinase enzyme, thereby lowering inflammation and symptoms associated with rheumatoid and psoriatic arthritis. 
 
In some cases, you may experience common side-effects such as diarrhoea, headache, upper respiratory tract infection, cold, nausea, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Inform your doctor if you have an active infection, if you have a condition that increases the chance of having infections, if you are taking immunosuppressants, medicines that affect the immune system or corticosteroids. Avoid taking Tofagod-11 ER Tablet if you are pregnant or breastfeeding. Tofagod-11 ER Tablet is not recommended for children below 18 years as safety and effectiveness have not been established. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Tofagod-11 ER Tablet

Rheumatoid arthritis, Psoriatic arthritis, Ulcerative colitis.

Medicinal Benefits Mweb

Medicinal Benefits

Tofagod-11 ER Tablet belongs to a group of medicines called Janus kinase inhibitors used to treat rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. Tofagod-11 ER Tablet works by blocking Janus kinase enzyme, thereby lowering inflammation and symptoms associated with rheumatoid and psoriatic arthritis. Tofagod-11 ER Tablet is indicated for patients with moderate to severe rheumatic arthritis, and psoriatic arthritis who have had intolerance or inadequate response to methotrexate or DMARDs (Disease-Modifying Anti-Rheumatic Drugs).

Directions for Use

Swallow Tofagod-11 ER Tablet as a whole with a glass of water; do not chew or break it.

Side Effects of Tofagod-11 ER Tablet

  • Headache
  • Diarrhoea
  • Vomiting
  • Nausea
  • Upper respiratory tract infection
  • Cold
  • High blood pressure

Drug Warnings

Do not take Tofagod-11 ER Tablet if you are allergic to any of its components; if you have a severe infection, bloodstream infection, active tuberculosis, or if you have severe liver problems such as cirrhosis. Avoid taking Tofagod-11 ER Tablet if you are pregnant or breastfeeding. Inform your doctor if you have an infection, symptoms of infection, a condition that increases chances of infection, are taking any medicines that affect the immune system; have or had a history of tuberculosis, or were in close contact with someone who has/had tuberculosis; chronic lung disease, liver problems, hepatitis B/C, cancer, are at a high risk of developing skin cancer, inflammation/ulcers of the large intestine, kidney problems, planning to get vaccinated, heart problems, high cholesterol, high blood pressure, heart attack, diabetes, or blood clotting problems. If your white blood cell count or red blood cell count is low, avoid taking Tofagod-11 ER Tablet . Tofagod-11 ER Tablet is not recommended for children below 18 years as safety and effectiveness have not been established. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Drug-Drug Interactions

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TofacitinibCisplatin
Severe
TofacitinibFluorouracil
Severe

Drug-Drug Interactions

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TofacitinibCisplatin
Severe
How does the drug interact with Tofagod-11 ER Tablet:
Taking Tofagod-11 ER Tablet with cisplatin may increase the risk of serious infection.

How to manage the interaction:
Although there is a possible interaction between Tofagod-11 ER Tablet and Cisplatin, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting your doctor.
TofacitinibFluorouracil
Severe
How does the drug interact with Tofagod-11 ER Tablet:
Using Tofagod-11 ER Tablet together with fluorouracil may increase the risk of serious infections.

How to manage the interaction:
Although there is a interaction between Tofagod-11 ER Tablet and fluorouracil but can be taken if advised by a doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting doctor.
TofacitinibBoceprevir
Severe
How does the drug interact with Tofagod-11 ER Tablet:
Taking Tofagod-11 ER Tablet with Boceprevir may increases the blood levels of Tofagod-11 ER Tablet which increases risk of side effects.

How to manage the interaction:
There may be a possibility of interaction between Tofagod-11 ER Tablet and Boceprevir, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience fatigue, dizziness, fainting, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting your doctor.
TofacitinibDactinomycin
Severe
How does the drug interact with Tofagod-11 ER Tablet:
Taking Tofagod-11 ER Tablet with Dactinomycin may increase the risk of serious infection.

How to manage the interaction:
Taking Dactinomycin with Tofagod-11 ER Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you experience any complications, infections, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, or pain or burning when you pee, make sure to call your doctor right away. Do not stop using any medications without first talking to your doctor.
TofacitinibIfosfamide
Severe
How does the drug interact with Tofagod-11 ER Tablet:
Taking Ifosfamide with Tofagod-11 ER Tablet may increase the risk of serious infection.

How to manage the interaction:
Taking Tofagod-11 ER Tablet with Ifosfamide together can possibly result in an interaction, but it can be taken if your doctor has advised it. It is important to keep a close eye on your condition. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
TofacitinibAtazanavir
Severe
How does the drug interact with Tofagod-11 ER Tablet:
Taking Tofagod-11 ER Tablet with atazanavir may increase the blood levels of Tofagod-11 ER Tablet. This may lead to cause severe infections.

How to manage the interaction:
Co-administration of Tofagod-11 ER Tablet with Atazanavir can possibly result in an interaction, but it can be taken if your doctor has advised it. However consult your doctor if you experience fatigue, dizziness, fainting, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without talking to your doctor.
TofacitinibPosaconazole
Severe
How does the drug interact with Tofagod-11 ER Tablet:
Posaconazole can raise the levels of Tofagod-11 ER Tablet in the bloodstream. You may experience increased side effects, including low blood cell counts, anemia, severe infections, and elevated blood lipid levels.

How to manage the interaction:
Although using Posaconazole and Tofagod-11 ER Tablet together can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact your doctor if you experience any side effects of Tofagod-11 ER Tablet, such as exhaustion, dizziness, fainting, fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop taking any medications without consulting a doctor.
TofacitinibVoriconazole
Severe
How does the drug interact with Tofagod-11 ER Tablet:
When Tofagod-11 ER Tablet is taken with Voriconazole may increase the risk of side effects.

How to manage the interaction:
Although taking Voriconazole and Tofagod-11 ER Tablet together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience dizziness, fever, shortness of breath, and pain or burning during urination, contact a doctor right away. Do not discontinue any medications without consulting a doctor.
TofacitinibPaclitaxel
Severe
How does the drug interact with Tofagod-11 ER Tablet:
Taking Tofagod-11 ER Tablet with Paclitaxel may increase the risk of infection.

How to manage the interaction:
Although taking Paclitaxel and Tofagod-11 ER Tablet together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
TofacitinibDacarbazine
Severe
How does the drug interact with Tofagod-11 ER Tablet:
Taking Dacarbazine with Tofagod-11 ER Tablet may increase the risk of serious infection.

How to manage the interaction:
There may be a possibility of interaction between Dacarbazine and Tofagod-11 ER Tablet, but it can be taken if prescribed by a doctor. If you have any of these symptoms - infection, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain or burning during urination - contact your doctor right away. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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TOFACITINIB-11MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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TOFACITINIB-11MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit, Grapefruit Juice

How to manage the interaction:
Consuming grapefruit products while taking Tofagod-11 ER Tablet can increase the risk of side effects. Avoid consuming grapefruit products while being treated with Tofagod-11 ER Tablet, as it can lead to an interaction.

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • RIFAMPICIN
  • FLUCONAZOLE
  • KETOCONAZOLE
  • AZATHIOPRINE
  • MERCAPTOPURINE
  • CYCLOSPORINE
  • TACROLIMUS
  • PREDNISONE

Habit Forming

No

Special Advise

  • Your doctor may advise you to get a blood test done before starting treatment with Tofagod-11 ER Tablet , after 4-8weeks of treatment and then every three months to determine your blood cell count.
  • Your doctor might advise regular tests to determine blood cholesterol levels and liver functioning.
  • Inform your doctor if you notice painful blisters on the skin or if you experience breathing difficulties.
  • If you are a woman of child-bearing potential, use effective contraception during the treatment with Tofagod-11 ER Tablet and for 4 weeks after discontinuation.

Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep, as resting the muscles can help in reducing inflammation and swelling.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

Tofagod-11 ER Tablet Substitute

Substitutes safety advice
  • Tofashine XR 11 mg Tablet 10's

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    85.50per tablet
  • Tfct-Nib OD 11 Tablet 10's

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    78.17per tablet
  • Aztofa XR 11 mg Tablet 10's

    by Others

    85.50per tablet
  • Tofadoz-11 XR Tablet 10's

    by Others

    64.17per tablet
  • Exnib Od 11 mg Tablet 15's

    by Others

    67.50per tablet
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